Decrease of laminin-511 in the basement membrane due to photoaging reduces epidermal stem/progenitor cells.

abstract：:Mycoplasma pneumoniae infection is conventionally diagnosed using serum antibody testing, microbial culture, and genetic testing. Recently, immunochromatography-based rapid mycoplasma antigen test kits have been developed and commercialised for rapid diagnosis of M. pneumoniae infection. However, as these kits do not ...

journal_title：Scientific reports

authors： Namkoong H,Yamazaki M,Ishizaki M,Endo I,Harada N,Aramaki M,Tanaka Y,Kaburagi S,Ichikawa M,Ohata T,Sakaguchi S,Saito F,Nakao A,Yuki H,Mitamura K

更新日期：2018-01-23 00:00:00

abstract：:The PRL phosphatases are oncogenic when overexpressed but their in vivo biological function is less well understood. Previous gene deletion study revealed a role for PRL2 in spermatogenesis. We report here the first knockout mice lacking PRL1, the most related homolog of PRL2. We found that loss of PRL1 does not affec...

journal_title：Scientific reports

authors： Bai Y,Zhou HM,Zhang L,Dong Y,Zeng Q,Shou W,Zhang ZY

更新日期：2016-09-26 00:00:00

abstract：:Tumor aggressiveness is usually associated with metastasis. MDA-MB 231, a triple-negative breast cancer (TNBC), is an aggressive type of breast cancer and associated with early metastasis. The Rho/ROCK pathway is a key regulator of cell motility involving cytoskeleton regulation through stabilization of actin filament...

journal_title：Scientific reports

authors： Guerra FS,Oliveira RG,Fraga CAM,Mermelstein CDS,Fernandes PD

更新日期：2017-10-20 00:00:00

abstract：:The dissolution of ferrihydrite induced by low molar mass (LMM) organics is an important process that provides bioavailable iron for organisms. Here, ATR-FTIR analysis was combined with characterization of ferrihydrite nanoparticles and kinetic modeling to investigate the roles of different oxalate surface complex spe...

journal_title：Scientific reports

authors： Li F,Koopal L,Tan W

更新日期：2018-02-01 00:00:00

abstract：:Understanding virulence is vital for the development of novel therapeutics to target infections with community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA), which cause an ongoing epidemic in the United States and are on a global rise. However, what defines virulence particularly of global CA-MRSA ...

journal_title：Scientific reports

authors： Li M,Dai Y,Zhu Y,Fu CL,Tan VY,Wang Y,Wang X,Hong X,Liu Q,Li T,Qin J,Ma X,Fang J,Otto M

更新日期：2016-06-14 00:00:00

abstract：:This study shows that DKK-1, a member of the Dickkopf family and a regulator of the Wnt pathways, represents a novel target of statins which, through the inhibition of HMG-CoA reductase and of non-steroidal isoprenoid intermediates, exert extra-beneficial effect in preventing atherosclerosis beyond their effect on the...

journal_title：Scientific reports

authors： Pontremoli M,Brioschi M,Baetta R,Ghilardi S,Banfi C

更新日期：2018-11-12 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Xu S,Fan S,Fang S,Lang X,Wang Y,Chen J

更新日期：2020-05-26 00:00:00

abstract：:Oil repellent surface have lots of practical applications in many fields. Current oil repellent coating may suffer from limited liquid repellency to oils or environmental risks. In this work, we report an eco-friendly 'green' processes for preparing oil-repellent surface using a renewable and environmentally benign bi...

journal_title：Scientific reports

authors： Xu LP,Han D,Wu X,Zhang Q,Zhang X,Wang S

更新日期：2016-11-29 00:00:00

abstract：:Chemical purity of RNA samples is important for high-precision studies of RNA folding and catalytic behavior, but photodamage accrued during ultraviolet (UV) shadowing steps of sample preparation can reduce this purity. Here, we report the quantitation of UV-induced damage by using reverse transcription and single-nuc...

journal_title：Scientific reports

authors： Kladwang W,Hum J,Das R

更新日期：2012-01-01 00:00:00

abstract：:Discovered in 1813, the conoscopic interference pattern observed due to light propagating through a crystal, kept between crossed polarizers, shows isochromates and isogyres, respectively containing information about the dynamic and geometric phase acquired by the beam. We propose and demonstrate a closed-fringe Fouri...

journal_title：Scientific reports

authors： Samlan CT,Naik DN,Viswanathan NK

更新日期：2016-09-14 00:00:00

abstract：:Patients with liver cirrhosis are susceptible to infections with high short-term mortalities. One CD97-related EGF-TM7 molecule, EMR2 (EGF-like molecule containing mucin-like hormone receptor 2), had been shown to regulate human neutrophil function, potentiate systemic inflammation. Nevertheless, EMR2 could also suppr...

journal_title：Scientific reports

authors： Huang CH,Jeng WJ,Ho YP,Teng W,Hsieh YC,Chen WT,Chen YC,Lin HH,Sheen IS,Lin CY

更新日期：2016-12-01 00:00:00

abstract：:Droplet microfluidics has attracted significant interests in functional microcapsule synthesis, pharmaceuticals, fine chemicals, cosmetics and biomedical research. The low variability of performing chemical reactions inside droplets could benefit from improved homogeneity and reproducibility. Therefore, accurate and c...

journal_title：Scientific reports

authors： Zhu X,Su S,Fu M,Liu J,Zhu L,Yang W,Jing G,Guo Y

更新日期：2018-07-02 00:00:00

abstract：:Methicillin-resistant Staphylococcus aureus (MRSA), are the most frequent cause of sepsis, which urgently demanding new drugs for treating infection. Two homologous insect CSαβ peptides-DLP2 and DLP4 from Hermetia illucens were firstly expressed in Pichia pastoris, with the yields of 873.5 and 801.3 mg/l, respectively...

journal_title：Scientific reports

authors： Li Z,Mao R,Teng D,Hao Y,Chen H,Wang X,Wang X,Yang N,Wang J

更新日期：2017-09-21 00:00:00

abstract：:As we move, perceptual stability is crucial to successfully interact with our environment. Notably, the brain must update the locations of objects in space using extra-retinal signals. The vestibular system is a strong candidate as a source of information for spatial updating as it senses head motion. The ability to u...

journal_title：Scientific reports

authors： Mackrous I,Carriot J,Simoneau M

更新日期：2019-08-01 00:00:00

abstract：:Clinical trials have recently demonstrated the effectiveness of Pre-Exposure Prophylaxis (PrEP) in preventing HIV infection. Consequently, PrEP may soon be used for epidemic control. We model the dynamic interactions that will occur between treatment programs and potential PrEP interventions in resource-constrained co...

journal_title：Scientific reports

authors： Supervie V,Barrett M,Kahn JS,Musuka G,Moeti TL,Busang L,Blower S

更新日期：2011-01-01 00:00:00

abstract：:Soil microbial communities directly affect soil functionality through their roles in the cycling of soil nutrients and carbon storage. Microbial communities vary substantially in space and time, between soil types and under different land management. The mechanisms that control the spatial distributions of soil microb...

journal_title：Scientific reports

authors： Xue PP,Carrillo Y,Pino V,Minasny B,McBratney AB

更新日期：2018-08-06 00:00:00

abstract：:The empirical research on the public goods game (PGG) indicates that both institutional rewards and institutional punishment can curb free-riding and that the punishment effect is stronger than the reward effect. Self-regarding models that are based on Nash equilibrium (NE) strategies or evolutionary game dynamics cor...

journal_title：Scientific reports

authors： Dong Y,Zhang B,Tao Y

更新日期：2016-06-24 00:00:00

abstract：:Tumor-associated immune response plays a critical role in cancer pathogenesis. This study evaluated clinical implications of T cell cytokines and regulatory T cells (Tregs) in HCC patients treated with TACE. Whole blood was obtained for analysis of T cell cytokines (IL-1β, IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12p70...

journal_title：Scientific reports

authors： Lee HL,Jang JW,Lee SW,Yoo SH,Kwon JH,Nam SW,Bae SH,Choi JY,Han NI,Yoon SK

更新日期：2019-03-01 00:00:00

abstract：:Lithium vanadium phosphate (Li3V2(PO4)3, LVP)/reduced graphene oxide (rGO) composite is prepared with a rheological method followed by heat treatment. The size and interface of LVP particles, two important merits for a cathode material, can be effectively tuned by the rGO in the composite, which plays as surfactant to...

journal_title：Scientific reports

authors： Zhu X,Yan Z,Wu W,Zeng W,Du Y,Zhong Y,Zhai H,Ji H,Zhu Y

更新日期：2014-08-29 00:00:00

abstract：:The dynamic structure of proteins is essential for their functions and may include large conformational transitions which can be studied by molecular dynamics (MD) simulations. However, details of these transitions are difficult to automatically track. To facilitate their analysis, we developed two scores of correlati...

journal_title：Scientific reports

authors： Taddese B,Garnier A,Abdi H,Henrion D,Chabbert M

更新日期：2020-09-28 00:00:00

abstract：:This study was intended to determine the efficacy of nivolumab, we evaluated treatment response with respect to PD-1/PD-L1 SNPs among patients with NSCLC. A total of 50 patients with NSCLC were treated with nivolumab and were also evaluated for PD-1/PD-L1 single nucleotide polymorphisms (SNPs) from plasma DNA. We inve...

journal_title：Scientific reports

authors： Nomizo T,Ozasa H,Tsuji T,Funazo T,Yasuda Y,Yoshida H,Yagi Y,Sakamori Y,Nagai H,Hirai T,Kim YH

更新日期：2017-03-23 00:00:00

abstract：:The neural substrates by which speech sounds are perceptually segregated into distinct streams are poorly understood. Here, we recorded high-density scalp event-related potentials (ERPs) while participants were presented with a cyclic pattern of three vowel sounds (/ee/-/ae/-/ee/). Each trial consisted of an adaptatio...

journal_title：Scientific reports

authors： Alain C,Arsenault JS,Garami L,Bidelman GM,Snyder JS

更新日期：2017-01-19 00:00:00

abstract：:Identification of novel photosynthetic proteins is important for understanding and improving photosynthetic efficiency. Synergistically, genome neighborhood can provide additional useful information to identify photosynthetic proteins. We, therefore, expected that applying a computational approach, particularly machin...

journal_title：Scientific reports

authors： Sangphukieo A,Laomettachit T,Ruengjitchatchawalya M

更新日期：2020-04-28 00:00:00

abstract：:This study aimed to quantify arterial volume distensibility in patients with branch retinal vein occlusion (BRVO) in comparison with normal subjects and to investigate factors associated with their differences. 40 normal subjects and 30 BRVO patients were studied. Brachial-ankle pulse wave velocity (baPWV) was measure...

journal_title：Scientific reports

authors： Chen Z,Mao L,Liu C,Blake JR,Zheng D

更新日期：2014-10-20 00:00:00

abstract：:The aim of the current manuscript was to test the applicability of a nanocomposite system of penetration enhancer vesicles (PEVs) within polymeric in situ forming gel network composed of poloxamer and hyaluronic acid for the intranasal delivery of the antiemetic dimenhydrinate (DMH). PEVs were prepared using phospholi...

journal_title：Scientific reports

authors： Barakat SS,Nasr M,Ahmed RF,Badawy SS,Mansour S

更新日期：2017-08-30 00:00:00

abstract：:Bisphenol (BP)A is an endocrine disruptor (ED) widely used in thermal papers. Regulatory restrictions have been established to prevent risks for human health, leading to BPA substitution by structural analogues, like BPS and BPF. We previously demonstrated that oral perinatal exposure to BPA had long-term consequences...

journal_title：Scientific reports

authors： Malaisé Y,Lencina C,Cartier C,Olier M,Ménard S,Guzylack-Piriou L

更新日期：2021-01-18 00:00:00

abstract：:Herein, we propose a new strategy of maskless lithographic approach to fabricate micro/nano-porous structures by phase separation of polystyrene (PS)/Polyethylene glycol (PEG) immiscible polymer blend. Its simple process only involves a spin coating of polymer blend followed by a development with deionized water rinse...

journal_title：Scientific reports

authors： Guo X,Liu L,Zhuang Z,Chen X,Ni M,Li Y,Cui Y,Zhan P,Yuan C,Ge H,Wang Z,Chen Y

更新日期：2015-10-30 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Liu H,Lv P,Zhu Y,Wu H,Zhang K,Xu F,Zheng L,Zhao J

更新日期：2020-09-09 00:00:00

abstract：:Many tissues exhibit subatmospheric interstitial pressures under normal physiologic conditions. The mechanisms by which the lymphatic system extracts fluid from these tissues against the overall pressure gradient are unknown. We address this important physiologic issue by combining experimental measurements of contrac...

journal_title：Scientific reports

authors： Jamalian S,Jafarnejad M,Zawieja SD,Bertram CD,Gashev AA,Zawieja DC,Davis MJ,Moore JE Jr

更新日期：2017-09-21 00:00:00

abstract：:Metabolic images from Positron Emission Tomography (PET) are used routinely for diagnosis, follow-up or treatment planning purposes of cancer patients. In this study we aimed at determining if radiomic features extracted from 18F-Fluoro Deoxy Glucose (FDG) PET images could mirror tumor transcriptomics. In this study w...

journal_title：Scientific reports

authors： Tixier F,Cheze-le-Rest C,Schick U,Simon B,Dufour X,Key S,Pradier O,Aubry M,Hatt M,Corcos L,Visvikis D

更新日期：2020-03-27 00:00:00