Sex-specific increase in susceptibility to metabolic syndrome in adult offspring after prenatal ethanol exposure with post-weaning high-fat diet.

abstract：:Many experimental techniques rely on specific recognition and stringent binding of proteins by antibodies. This can readily be achieved by introducing an epitope tag. We employed an approach that uses a relative lack of evolutionary conservation to inform epitope tag site selection, followed by integration of the tag-...

journal_title：Scientific reports

authors： Burg L,Zhang K,Bonawitz T,Grajevskaja V,Bellipanni G,Waring R,Balciunas D

更新日期：2016-11-28 00:00:00

abstract：:Common features of immune-metabolic and inflammatory diseases such as metabolic syndrome, diabetes, obesity and cardiovascular diseases are an altered gut microbiota composition and a systemic pro-inflammatory state. We demonstrate that active immunization against the outer membrane protein of bacteria present in the ...

journal_title：Scientific reports

authors： Saita D,Ferrarese R,Foglieni C,Esposito A,Canu T,Perani L,Ceresola ER,Visconti L,Burioni R,Clementi M,Canducci F

更新日期：2016-07-07 00:00:00

abstract：:Transition Metal Dichalcogenides (TMDs) are one of the most studied two-dimensional materials in the last 5-10 years due to their extremely interesting layer dependent properties. Despite the presence of vast research work on TMDs, the complex relation between the electro-chemical and physical properties make them the...

journal_title：Scientific reports

authors： Ghatak K,Kang KN,Yang EH,Datta D

更新日期：2020-02-03 00:00:00

abstract：:Kuding tea is implicated in alleviating metabolic disorders in traditional Chinese medicine. However, the role of Ilex latifolia Thunb (kuding tea), one of the large leaf kuding tea species, in the prevention of the development of obesity remains to be determined. We show here that 7-week-old male mice treated with an...

journal_title：Scientific reports

authors： Wu H,Chen YL,Yu Y,Zang J,Wu Y,He Z

更新日期：2017-11-07 00:00:00

abstract：:The theoretical optimal olfactory search strategy is to move cross-wind. Empirical evidence supporting wind-associated directionality among carnivores, however, is sparse. We examined satellite-linked telemetry movement data of adult female polar bears (Ursus maritimus) from Hudson Bay, Canada, in relation to modelled...

journal_title：Scientific reports

authors： Togunov RR,Derocher AE,Lunn NJ

更新日期：2017-04-12 00:00:00

abstract：:The regular rise and fall of the sun resulted in the development of 24-h rhythms in virtually all organisms. In an evolutionary heartbeat, humans have taken control of their light environment with electric light. Humans are highly sensitive to light, yet most people now use light until bedtime. We evaluated the impact...

journal_title：Scientific reports

authors： Cain SW,McGlashan EM,Vidafar P,Mustafovska J,Curran SPN,Wang X,Mohamed A,Kalavally V,Phillips AJK

更新日期：2020-11-05 00:00:00

abstract：:Antibiotic-resistant bacterial infections are a substantial source of morbidity and mortality and have a common reservoir in inpatient settings. Transferring patients between facilities could be a mechanism for the spread of these infections. We wanted to assess whether a network of hospitals, linked by inpatient tran...

journal_title：Scientific reports

authors： Fernández-Gracia J,Onnela JP,Barnett ML,Eguíluz VM,Christakis NA

更新日期：2017-06-07 00:00:00

abstract：:Bone is the most common site of metastasis in metastatic castration-resistant prostate cancer (mCRPC), which is associated with pain and skeletal events. Radium-223 dichloride (Xofigo) is an alpha-emitting radioactive isotope that can specifically target bone lesions. Herein, we report the results of a retrospective a...

journal_title：Scientific reports

authors： Rizzini EL,Dionisi V,Ghedini P,Morganti AG,Fanti S,Monari F

更新日期：2020-04-21 00:00:00

abstract：:At 50 kg in estimated weight, the extinct Siamogale melilutra is larger than all living otters, and ranks among the largest fossil otters. The biomechanical capability of S. melilutra jaws as related to their large size is unknown but crucial to reconstructing the species' potentially unique ecological niche. Here we ...

journal_title：Scientific reports

authors： Tseng ZJ,Su DF,Wang X,White SC,Ji X

更新日期：2017-11-09 00:00:00

abstract：:Electrochemical biosensors have been studied intensively for several decades. Numerous sensing concepts and related interface architectures have been developed. However, all such architectures suffer a trade-off: simple architectures favour usability, whereas complex architectures favour better performance. To overcom...

journal_title：Scientific reports

authors： Zhu X,Feng C,Ye Z,Chen Y,Li G

更新日期：2014-02-25 00:00:00

abstract：:Anopheles gambiae and Aedes aegypti are perhaps the best studied mosquito species and important carriers of human malaria and arbovirus, respectively. Mosquitoes have daily rhythms in behaviors and show a wide range of activity patterns. Although Anopheles is known to be principally nocturnal and Aedes principally diu...

journal_title：Scientific reports

authors： Araujo MDS,Guo F,Rosbash M

更新日期：2020-03-19 00:00:00

abstract：:Aerosols impact clear-sky surface irradiance () through the effects of scattering and absorption. Linear or nonlinear relationships between aerosol optical depth (τa) and have been established to describe the aerosol direct radiative effect on (ADRE). However, considerable uncertainties remain associated with ADRE due...

journal_title：Scientific reports

authors： Xia X

更新日期：2015-09-23 00:00:00

abstract：:We investigated the mechanism with which humans estimate numerical averages. Participants were presented with 4, 8 or 16 (two-digit) numbers, serially and rapidly (2 numerals/second) and were instructed to convey the sequence average. As predicted by a dual, but not a single-component account, we found a non-monotonic...

journal_title：Scientific reports

authors： Brezis N,Bronfman ZZ,Usher M

更新日期：2015-06-04 00:00:00

abstract：:In this study we measured the degrees to which the Schottky barrier heights (SBHs) are lowered in ZnO nanowire (NW) devices under illumination with UV light. We measured the I-V characteristics of ZnO nanowire devices to confirm that ZnO is an n-type semiconductor and that the on/off ratio is approximately 10(4). From...

journal_title：Scientific reports

authors： Lu MY,Lu MP,You SJ,Chen CW,Wang YJ

更新日期：2015-10-12 00:00:00

abstract：:Adverse maternal environments, such as diabetes and obesity, impair placental mitochondrial function, which affects fetal development and offspring long-term health. The underlying mechanisms and effective interventions to abrogate such effect remain unclear. Our previous studies demonstrated impaired mitochondrial bi...

journal_title：Scientific reports

authors： Jiang S,Teague AM,Tryggestad JB,Jensen ME,Chernausek SD

更新日期：2020-05-20 00:00:00

abstract：:Comparative genomic studies in primates have the potential to reveal the genetic and mechanistic basis for human specific traits. These studies may also help us better understand inter-species phenotypic differences that are clinically relevant. Unfortunately, the obvious limitation on sample collection and experiment...

journal_title：Scientific reports

authors： Pavlovic BJ,Blake LE,Roux J,Chavarria C,Gilad Y

更新日期：2018-10-17 00:00:00

abstract：:The Maxwellian near-eye displays have attracted growing interest in various applications. By using a confined pupil, a Maxwellian display presents an all-in-focus image to the viewer where the image formed on the retina is independent of the optical power of the eye. Despite being a promising technique, current Maxwel...

journal_title：Scientific reports

authors： Chang C,Cui W,Park J,Gao L

更新日期：2019-12-10 00:00:00

abstract：:Environmental cycles often influence the presence of animals, creating patterns at different temporal scales, which may mean that their effects overlap and/or interact. Interactions between diel and seasonal cycles have been reported to influence fish behaviour but little is known about such interactions in marine top...

journal_title：Scientific reports

authors： Fernandez-Betelu O,Graham IM,Cornulier T,Thompson PM

更新日期：2019-02-22 00:00:00

abstract：:Jellyfish stingings are currently raising serious public health concerns around the world. Hence, the search for an effective first aid reagent for the envenomation has been the goal of many investigators in the field. There have been a few previous reports of in vivo as well as in vivo studies suggesting the metallop...

journal_title：Scientific reports

authors： Hwang DH,Lee H,Choudhary I,Kang C,Chae J,Kim E

更新日期：2020-10-29 00:00:00

abstract：:For infants with acute progressive hydrocephalus, invasive drainage of cerebrospinal fluid (CSF) is performed until a ventriculo-peritoneal shunt can be inserted. Surrogate markers of intracranial pressure (ICP) may help optimise the timing of invasive procedures. To assess whether RI with/without fontanel compression...

journal_title：Scientific reports

authors： Yoshizuka T,Kinoshita M,Iwata S,Tsuda K,Kato T,Saikusa M,Shindou R,Hara N,Harada E,Takashima S,Takeshige N,Saitoh S,Yamashita Y,Iwata O

更新日期：2018-08-07 00:00:00

abstract：:Ehrlichia chaffeensis, a tick-transmitted rickettsial bacterium, is the causative agent of human monocytic ehrlichiosis. Biochemical characterization of this and other related Rickettsiales remains a major challenge, as they require a host cell for their replication. We investigated the use of an axenic medium for E. ...

journal_title：Scientific reports

authors： Eedunuri VK,Zhang Y,Cheng C,Chen L,Liu H,Omsland A,Boyle D,Ganta RR

更新日期：2018-06-18 00:00:00

abstract：:The aim of this study is to explore the differentially expressed lncRNAs, which may have potential biological function and diagnostic value in colorectal cancer (CRC). Through integrated data mining, we finally identified nine differentially expressed lncRNAs and their potential mRNA targets. After a series of bioinfo...

journal_title：Scientific reports

authors： Dai M,Chen X,Mo S,Li J,Huang Z,Huang S,Xu J,He B,Zou Y,Chen J,Dai S

更新日期：2017-04-13 00:00:00

abstract：:The Notch signaling network determines stemness in various tissues and targeting signaling activity in malignant brain cancers by gamma-secretase inhibitors (GSI) has shown promising preclinical success. However, the clinical translation remains challenging due to severe toxicity side effects and emergence of therapy ...

journal_title：Scientific reports

authors： Herrera-Rios D,Li G,Khan D,Tsiampali J,Nickel AC,Aretz P,Hewera M,Suwala AK,Jiang T,Steiger HJ,Kamp MA,Muhammad S,Hänggi D,Maciaczyk J,Zhang W,Kahlert UD

更新日期：2020-10-01 00:00:00

abstract：:Split bull's eye (SBE) antennas exhibit much larger extraordinary optical transmission and strong polarization dependence rather than bull's eye (BE) antennas in the infrared range due to the introduced sub-wavelength slit. Here, we demonstrate a dual-split bull's eye (DSBE) antenna, which consists of two sub-waveleng...

journal_title：Scientific reports

authors： Yang M,Ren FF,Pu L,Xiao L,Sheng Y,Wang J,Lu H,Zheng Y,Shi Y

更新日期：2016-12-19 00:00:00

abstract：:Use of human induced pluripotent stem cells (h-iPSCs) for bone tissue engineering is most appealing, because h-iPSCs are an inexhaustible source of osteocompetent cells. The present study investigated the contribution of undifferentiated h-iPSCs and elucidated aspects of the underlying mechanism(s) of the involvement ...

journal_title：Scientific reports

authors： Oudina K,Paquet J,Moya A,Massourides E,Bensidhoum M,Larochette N,Deschepper M,Pinset C,Petite H

更新日期：2018-11-20 00:00:00

abstract：:Fat character is an important index in duck culture that linked to local flavor, feed cost and fat intake for costumers. Since the regulation networks in duck lipid metabolism had not been reported very clearly, we aimed to explore the potential miRNA-mRNA pairs and their regulatory roles in duck lipid metabolism. Her...

journal_title：Scientific reports

authors： He J,Wang W,Lu L,Tian Y,Niu D,Ren J,Dong L,Sun S,Zhao Y,Chen L,Shen J,Li X

更新日期：2016-06-08 00:00:00

abstract：:We report the impact of anti-urothelial autoantibody (AUAb) on urinary bladder phenotype in BALB/c mice deficient of the FcγRIIb and PD-1. AUAb was present in serum samples from approximately half of the double-knockout (DKO) mice, as detected by immunofluorescence and immunoblots for urothelial proteins including uro...

journal_title：Scientific reports

authors： Sugino Y,Nishikawa N,Yoshimura K,Kuno S,Hayashi Y,Yoshimura N,Okazaki T,Kanematsu A,Ogawa O

更新日期：2012-01-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is an important risk factor for the development of type 2 diabetes mellitus. Interferon gamma-induced protein 10 (IP-10), a proinflammatory chemokine, plays a crucial role in inflammatory diseases. This cross-sectional pilot study investigated whether circulating IP-10 is assoc...

journal_title：Scientific reports

authors： Chang CC,Wu CL,Su WW,Shih KL,Tarng DC,Chou CT,Chen TY,Kor CT,Wu HM

更新日期：2015-05-11 00:00:00

abstract：:If the components of a battery, including electrodes, separator, electrolyte and the current collectors can be designed as paints and applied sequentially to build a complete battery, on any arbitrary surface, it would have significant impact on the design, implementation and integration of energy storage devices. Her...

journal_title：Scientific reports

authors： Singh N,Galande C,Miranda A,Mathkar A,Gao W,Reddy AL,Vlad A,Ajayan PM

更新日期：2012-01-01 00:00:00

abstract：:The balance between ovarian folliculogenesis and follicular atresia is critical for female fertility and is strictly regulated by a complex network of neuroendocrine and intra-ovarian signals. Despite the numerous functions executed by granulosa cells (GCs) in ovarian physiology, the role of multifunctional proteins a...

journal_title：Scientific reports

authors： Arcos A,de Paola M,Gianetti D,Acuña D,Velásquez ZD,Miró MP,Toro G,Hinrichsen B,Muñoz RI,Lin Y,Mardones GA,Ehrenfeld P,Rivera FJ,Michaut MA,Batiz LF

更新日期：2017-09-18 00:00:00