Meta-signature LncRNAs serve as novel biomarkers for colorectal cancer: integrated bioinformatics analysis, experimental validation and diagnostic evaluation.

abstract：:Stimulated by a recent experiment observing successfully two superconducting states with even- and odd-number of electrons in a nanowire topological superconductor as expected from the existence of two end Majorana quasiparticles (MQs) [Albrecht et al., Nature 531, 206 (2016)], we propose a way to manipulate Majorana ...

journal_title：Scientific reports

authors： Wang Z,Huang WC,Liang QF,Hu X

更新日期：2018-05-21 00:00:00

abstract：:The Asian citrus psyllid (ACP; Diaphorina citri) is the vector of Candidatus Liberibacter asiaticus (CLas) that is associated with the devastating Huanglongbing (HLB; citrus greening disease). This pest of Asian origin has spread into the Americas and more recently into a few countries in East Africa. During recent su...

journal_title：Scientific reports

authors： Oke AO,Oladigbolu AA,Kunta M,Alabi OJ,Sétamou M

更新日期：2020-06-10 00:00:00

abstract：:One of the health hazards of PM2.5 exposure is to induce pulmonary inflammatory responses. In our previous study, we demonstrated that exposing both the immortalized and primary human bronchial epithelial cells to PM2.5 results in a significant upregulation of VEGF production, a typical signaling event to trigger chro...

journal_title：Scientific reports

authors： Xu H,Xu X,Wang H,Qimuge A,Liu S,Chen Y,Zhang C,Hu M,Song L

更新日期：2019-11-12 00:00:00

abstract：:The behavior of diatomic molecular solids under pressure have attracted great interest and been extensively studied. Under ambient pressure, the structure of bromine is known to be a molecular phase (phase I). With increasing pressure, it transforms into an incommensurate phase (phase V) before eventually to a monoato...

journal_title：Scientific reports

authors： Wu M,Tse JS,Pan Y

更新日期：2016-05-09 00:00:00

abstract：:Numerous essential metal elements (EMEs) are necessary to maintain the proper function of human body. In this case-control study, we investigated the associations of 11 EMEs [Calcium (Ca), potassium (K), magnesium (Mg), sodium (Na), manganese (Mn), selenium (Se), cobalt (Co), Molybdenum (Mo), copper (Cu), zinc (Zn), a...

journal_title：Scientific reports

authors： Ma J,Yan L,Guo T,Yang S,Liu Y,Xie Q,Ni D,Wang J

更新日期：2020-07-03 00:00:00

abstract：:The metabolic impact of circulating fatty acids (FAs) in patients requiring hemodialysis (HD) is unknown. We investigated the associations between plasma triglyceride (TG) FAs and markers of inflammation, insulin resistance, nutritional status and body composition. Plasma TG-FAs were measured using gas chromatography ...

journal_title：Scientific reports

authors： Khor BH,Sahathevan S,Sualeheen A,Ali MSM,Narayanan SS,Chinna K,Gafor AHA,Goh BL,Ahmad G,Morad Z,Daud ZAM,Khosla P,Sundram K,Karupaiah T,PaTCH Investigators.

更新日期：2021-01-14 00:00:00

abstract：:Mesenchymal stem cells (MSC) are osteoblasts progenitors and a variety of studies suggest that they may play an important role for the health in the field of bone regeneration. Magnesium supplementation is gaining importance as adjuvant treatment to improve osteogenesis, although the mechanisms involving this process ...

journal_title：Scientific reports

authors： Díaz-Tocados JM,Herencia C,Martínez-Moreno JM,Montes de Oca A,Rodríguez-Ortiz ME,Vergara N,Blanco A,Steppan S,Almadén Y,Rodríguez M,Muñoz-Castañeda JR

更新日期：2017-08-10 00:00:00

abstract：:Anopheles gambiae and Aedes aegypti are perhaps the best studied mosquito species and important carriers of human malaria and arbovirus, respectively. Mosquitoes have daily rhythms in behaviors and show a wide range of activity patterns. Although Anopheles is known to be principally nocturnal and Aedes principally diu...

journal_title：Scientific reports

authors： Araujo MDS,Guo F,Rosbash M

更新日期：2020-03-19 00:00:00

abstract：:Rheumatoid arthritis (RA) patients have been observed to be at a lower risk of developing Alzheimer's Disease (AD). Clinical trials have showed no relationship between nonsteroidal anti-inflammatory drug (NSAID) use and AD. The aim of this study was to establish if there is a causal link between RA and AD. A systemati...

journal_title：Scientific reports

authors： Policicchio S,Ahmad AN,Powell JF,Proitsi P

更新日期：2017-10-09 00:00:00

abstract：:China has one of the highest rates of cesarean sections in the world. However, limited epidemiological studies have evaluated the risk factors for cesarean section among Chinese women. Thus, the aim of this cohort study was to investigate the associations between pre-pregnancy BMI, gestational weight gain (GWG) and th...

journal_title：Scientific reports

authors： Xiong C,Zhou A,Cao Z,Zhang Y,Qiu L,Yao C,Wang Y,Zhang B

更新日期：2016-11-22 00:00:00

abstract：:Here, we present a fast mix-and-measure immunoassay for the specific semiquantitative detection of His-tagged proteins, for example in E. coli cell lysate. The assay is based on Förster resonance energy transfer (FRET) between a lanthanide dye-labeled low-affinity His-peptide and an acceptor-labeled anti-His-tag antib...

journal_title：Scientific reports

authors： Kreisig T,Prasse AA,Zscharnack K,Volke D,Zuchner T

更新日期：2014-07-08 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Ravanbakhsh H,Bao G,Mongeau L

更新日期：2020-03-24 00:00:00

abstract：:Muscle differentiation is a complex process in which muscle progenitor cells undergo determination and eventually cellular fusion. This process is heavily regulated by such master transcription factors as MYOD and members of the MEF2 family. Here, we show that the transcription factor ZNF148 plays a direct role in hum...

journal_title：Scientific reports

authors： Bakke J,Wright WC,Zamora AE,Ong SS,Wang YM,Hoyer JD,Brewer CT,Thomas PG,Chen T

更新日期：2017-08-15 00:00:00

abstract：:Iron overload is associated with various pathological changes which contribute to heart failure. Here, we examined mechanisms via which iron alters cardiomyocyte insulin sensitivity. Treatment of primary adult and neonatal cardiomyocytes as well as H9c2 cells with iron decreased insulin sensitivity determined via West...

journal_title：Scientific reports

authors： Sung HK,Song E,Jahng JWS,Pantopoulos K,Sweeney G

更新日期：2019-03-15 00:00:00

abstract：:Next generation sequencing has disrupted genetic testing, allowing far more scope in the tests applied. The appropriate sections of the genome to be tested can now be readily selected, from single mutations to whole-genome sequencing. One product offering within this spectrum are focused exomes, targeting ~5,000 genes...

journal_title：Scientific reports

authors： Pengelly RJ,Ward D,Hunt D,Mattocks C,Ennis S

更新日期：2020-02-24 00:00:00

abstract：:Through the use of the technique of time-of-flight mass spectroscopy, we obtain strong-field ionization yields for randomly oriented 1,2-dichloroethylene (1,2-DCE) (C2H2Cl2) and 2-butene (C4H8). We are interested in studying the effect of conformal structure in strong-field ionization and, in particular, the role of m...

journal_title：Scientific reports

authors： Zigo S,Le AT,Timilsina P,Trallero-Herrero CA

更新日期：2017-02-10 00:00:00

abstract：:We recently reported that R-spondin 2 (Rspo2), a secreted activator of Wnt/β-catenin signaling, promotes acetylcholine receptor (AChR) clustering and neuromuscular junction (NMJ) formation via its receptor, Lgr5. Rspo2 is expressed highly in spinal motor neurons (SMNs) and marginally in the skeletal muscle, but the or...

journal_title：Scientific reports

authors： Li J,Ito M,Ohkawara B,Masuda A,Ohno K

更新日期：2018-09-11 00:00:00

abstract：:The small intestine plays an essential role in the health and well-being of animals. Previous studies have shown that Lactobacillus has a protective effect on intestinal morphology, intestinal epithelium integrity and appropriate maturation of gut-associated tissues. Here, gene expression in jejunum tissue of weaned p...

journal_title：Scientific reports

authors： Zhang D,Shang T,Huang Y,Wang S,Liu H,Wang J,Wang Y,Ji H,Zhang R

更新日期：2017-11-17 00:00:00

abstract：:Fine-motor impairment (FMI) is progressively expressed in early Parkinson's Disease (PD) patients and is now known to be evident in the immediate prodromal stage of the condition. The clinical techniques for detecting FMI may not be robust enough and here, we show that the subtle FMI of early PD patients can be effect...

journal_title：Scientific reports

authors： Iakovakis D,Chaudhuri KR,Klingelhoefer L,Bostantjopoulou S,Katsarou Z,Trivedi D,Reichmann H,Hadjidimitriou S,Charisis V,Hadjileontiadis LJ

更新日期：2020-07-28 00:00:00

abstract：:SerpinB3 has been recently described as an early marker of liver carcinogenesis, but the potential mechanistic role of this serpin in tumor development is still poorly understood. Overexpression of Myc often correlates with more aggressive tumour forms, supporting its involvement in carcinogenesis. Yes-associated prot...

journal_title：Scientific reports

authors： Turato C,Cannito S,Simonato D,Villano G,Morello E,Terrin L,Quarta S,Biasiolo A,Ruvoletto M,Martini A,Fasolato S,Zanus G,Cillo U,Gatta A,Parola M,Pontisso P

更新日期：2015-12-04 00:00:00

abstract：:Nitric oxide (NO) is an important signalling molecule involved in haemostasis. NO, present as endogenous S-nitrosothiols, is released by cysteine through a transnitrosation reaction. To exploit this mechanism, cysteine was immobilised onto the different carboxylated polyethylene terephthalate (PET) surfaces using 1-st...

journal_title：Scientific reports

authors： Ramachandran B,Muthuvijayan V

更新日期：2019-11-13 00:00:00

abstract：:Epithelial-mesenchymal transition (EMT) plays an important role in tumor invasion and metastasis. A comprehensive, bioinformatics analysis of CCLE and TCGA datasets of seven tumor types allowed us to identify a novel pan-cancer EMT-associated gene expression signature consisting of 16 epithelial and 4 mesenchymal stat...

journal_title：Scientific reports

authors： Rokavec M,Kaller M,Horst D,Hermeking H

更新日期：2017-07-05 00:00:00

abstract：:Toxins are believed to play a crucial role in Burkholderia pseudomallei pathogenicity, however to date, only a few have been identified. The discovery of additional toxic molecules is limited by the lack of a sensitive indicator of B. pseudomallei toxicity. Previously, from a whole genome transcriptome analysis of B. ...

journal_title：Scientific reports

authors： Wong RR,Kong C,Lee SH,Nathan S

更新日期：2016-06-07 00:00:00

abstract：:We present herein the use of nanoporous anodic alumina (NAA) as a suitable support to implement "molecular gates" for sensing applications. In our design, a NAA support is loaded with a fluorescent reporter (rhodamine B) and functionalized with a short single-stranded DNA. Then pores are blocked by the subsequent hybr...

journal_title：Scientific reports

authors： Ribes À,Xifré-Pérez E,Aznar E,Sancenón F,Pardo T,Marsal LF,Martínez-Máñez R

更新日期：2016-12-07 00:00:00

abstract：:Genetic alterations identified in adjacent normal appearing tissue in bladder cancer patients are indicative of a field disease. Here we assessed normal urothelium transformation and intra-tumour heterogeneity (ITH) in four patients with bladder cancer. Exome sequencing identified private acquired mutations in a lymph...

journal_title：Scientific reports

authors： Thomsen MBH,Nordentoft I,Lamy P,Vang S,Reinert L,Mapendano CK,Høyer S,Ørntoft TF,Jensen JB,Dyrskjøt L

更新日期：2017-09-15 00:00:00

abstract：:Patient misidentification in imaging examinations has become a serious problem in clinical settings. Such misidentification could be prevented if patient characteristics such as sex, age, and body weight could be predicted based on an image of the patient, with an alert issued when a mismatch between the predicted and...

journal_title：Scientific reports

authors： Kawauchi K,Hirata K,Katoh C,Ichikawa S,Manabe O,Kobayashi K,Watanabe S,Furuya S,Shiga T

更新日期：2019-05-10 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Wang Z,Wang H,Tzvetanov T,Zhou Y

更新日期：2019-05-23 00:00:00

abstract：:The analysis of equine electrocardiographic (ECG) recordings is complicated by the absence of agreed abnormality classification criteria. We explore the applicability of several complexity analysis methods for characterization of non-linear aspects of electrocardiographic recordings. We here show that complexity estim...

journal_title：Scientific reports

authors： Alexeenko V,Fraser JA,Dolgoborodov A,Bowen M,Huang CL,Marr CM,Jeevaratnam K

更新日期：2019-02-22 00:00:00

abstract：:Carbon fiber-synthetic foam core sandwich composites are widely used for many structural applications due to their superior mechanical performance and low weight. Unfortunately these structures typically have very poor acoustic performance. There is increasingly growing demand in mitigating this noise issue in sandwic...

journal_title：Scientific reports

authors： Sargianis J,Kim HI,Suhr J

更新日期：2012-01-01 00:00:00

abstract：:Animals are capable of using visual cues to find the correct route during navigation. These visual cues, which contain spatial information on the direction towards the goal point, are perceived either allocentrically or egocentrically. In this study, we examined how navigating with these two types of visual cues affec...

journal_title：Scientific reports

authors： Chun J,Kim Y,Choi JW,Kim D,Jo S

更新日期：2019-04-23 00:00:00