Usefulness of 11C-methionine-positron emission tomography for the diagnosis of progressive multifocal leukoencephalopathy.

abstract：:Prolonged clinico-immunological observation of 85 patients with definite multiple sclerosis (MS) was performed in order to elucidate the connections between the clinical and immune state. A battery of immunological investigations was performed, including estimation of T-cell subpopulations in blood and cerebrospinal f...

journal_title：Journal of neurology

authors： Gusev EI,Demina TL,Boiko AN,Pinegin BV

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Protein Z (PZ), a vitamin Kdependent protein, plays a role in inhibiting coagulation. Its plasma level or PZ gene polymorphisms have been discussed as risk factors for stroke with conflicting results reported between various studies. Only one of these polymorphisms was studied in a cohort of pati...

journal_title：Journal of neurology

authors： Le Cam-Duchez V,Bagan-Triquenot A,Barbay V,Mihout B,Borg JY

更新日期：2008-10-01 00:00:00

abstract：:A total of 15 patients affected by idiopathic dystonia (7 with generalized and 8 with focal or segmental dystonia) were subjected to therapy with bromocriptine at low doses, pimozide and trihexyphenidyl. The symptoms were evaluated by giving a progressive score in relation to the intensity of the dystonic symptom to e...

journal_title：Journal of neurology

authors： Girotti F,Scigliano G,Nardocci N,Angelini L,Broggi G,Giovannini P,Caraceni T

更新日期：1982-01-01 00:00:00

abstract：:Left-handedness is most often genetic, but may also follow early, localised damage to the developing brain. This so-called "pathological" left-handedness syndrome is often associated with right hemisphere speech dominance. To find out whether verbal laterality or handedness were affected by congenital, intracranial ar...

journal_title：Journal of neurology

authors： Wester K,Hugdahl K

更新日期：2003-01-01 00:00:00

abstract：:Acid maltase deficiency is described in non-identical adult twins. The onset of the disease can be traced into late infancy; the clinical picture is one of severe muscular dystrophy; respiratory insuficiency was the cause of death in one case. The autopsy showed the central nervous system, heart and liver to be spared...

journal_title：Journal of neurology

authors： Martin JJ,de Barsy T,den Tandt WR

更新日期：1976-08-06 00:00:00

abstract：BACKGROUND AND PURPOSE:Parkinson's disease (PD) is a neurodegenerative disorder characterized by deposition of intraneural inclusion bodies in the brain as well as the enteric nervous system. Emerging concepts regarding the brain-gut axis have been proposed for neurological disorders. Thus, the present study investigat...

journal_title：Journal of neurology

authors： Kim YJ,Lee CM,Kim S,Jang JW,Lee SY,Lee SH

更新日期：2020-02-01 00:00:00

abstract：:We wanted to determine the neurocognitive profile of adult patients with moyamoya disease prior to neurosurgical intervention. The experience of three United States medical centers, Columbia University, University of Illinois at Chicago, and the University of Texas Southwestern Medical Center at Dallas, were combined....

journal_title：Journal of neurology

authors： Festa JR,Schwarz LR,Pliskin N,Cullum CM,Lacritz L,Charbel FT,Mathews D,Starke RM,Connolly ES,Marshall RS,Lazar RM

更新日期：2010-05-01 00:00:00

abstract：:The association of pathology and neurological deficit with quality of life (QoL) in multiple sclerosis (MS) is not fully understood. In this study, magnetic resonance imaging (MRI) measures of pathology--T1 and T2 lesion volume and ratio; active T2 lesion number; global and regional brain volume and atrophy; magnetiza...

journal_title：Journal of neurology

authors： Hayton T,Furby J,Smith KJ,Altmann DR,Brenner R,Chataway J,Hunter K,Tozer DJ,Miller DH,Kapoor R

更新日期：2012-02-01 00:00:00

abstract：:The long-duration response (LDR) to levodopa is an important component of the therapeutic response to the drug in Parkinson's disease (PD). Some characteristics are peculiar: it is independent from peripheral pharmacokinetics of levodopa, but it is dependent on the intervals between doses and on the size of each dose....

journal_title：Journal of neurology

authors： Zappia M,Nicoletti A

更新日期：2010-11-01 00:00:00

abstract：:Recently, a frequent prion protein gene (PRNP) polymorphism consisting of a methionine (M) for valine (V) substitution at codon 129 has been associated with cognitive impairment in elderly individuals. Down syndrome (DS) is associated with mental retardation and development of Alzheimer-like brain abnormalities. In th...

journal_title：Journal of neurology

authors： Del Bo R,Comi GP,Giorda R,Crimi M,Locatelli F,Martinelli-Boneschi F,Pozzoli U,Castelli E,Bresolin N,Scarlato G

更新日期：2003-06-01 00:00:00

abstract：:We examined 199 consecutive patients who underwent 220 liver transplantations, to define the type, frequency and aetiology of posttransplant neurological complications and their prognostic value. We found neurological complications in 63 patients (32%), mostly involving the central nervous system. The most frequent co...

journal_title：Journal of neurology

authors： Guarino M,Stracciari A,Pazzaglia P,Sterzi R,Santilli I,Donato F,D'Alessandro R

更新日期：1996-02-01 00:00:00

abstract：:The last 5 years have seen rapid progress in Parkinson’s disease (PD) genetics, with the publication of a series of large-scale genome wide association studies for PD, and evaluation of the roles of the LRRK2 and GBA genes in the aetiology of PD. We are beginning to develop a coherent picture of the interplay of Mende...

journal_title：Journal of neurology

authors： Lubbe S,Morris HR

更新日期：2014-02-01 00:00:00

abstract：:Four patients from three unrelated families, with clinical and electrophysiological findings compatible with the diagnosis of hereditary motor and sensory neuropathy, are presented. The molecular analysis showed that the affected individuals were homozygous for the mutation in the X25 gene, characteristic of Friedreic...

journal_title：Journal of neurology

authors： Panas M,Kalfakis N,Karadima G,Davaki P,Vassilopoulos D

更新日期：2002-11-01 00:00:00

abstract：:The neutrotrophins stimulate survival and differentiation of a range of target neurons. A wealth of evidence suggests that central cholinergic neurons depend on nerve growth factor (NGF) for trophic support. Grafts of NGF-producing cells rescue axotomized basal forebrain cholinergic neurons and reduce cholinergic cell...

journal_title：Journal of neurology

authors： Ebendal T,Lönnerberg P,Pei G,Kylberg A,Kullander K,Persson H,Olson L

更新日期：1994-12-01 00:00:00

abstract：:The objective of the study was to identify differences in treatment strategies for anti-NMDA receptor encephalitis based on specialty of treating physicians, geographic location, and years in practice. We conducted an anonymous worldwide electronic survey through the Practice Current section of Neurology® Clinical Pra...

journal_title：Journal of neurology

authors： Bartolini L,Muscal E

更新日期：2017-04-01 00:00:00

abstract：:Clinical diagnosis of amyotrophic lateral sclerosis (ALS) in patients presenting with cramps and fasciculations may not be evident at the first consultation. Sequential reviews, clinical and neurophysiological, form an important part of clinical practice in such cases. Recent attempts to delineate a more benign group ...

journal_title：Journal of neurology

authors： Singh V,Gibson J,McLean B,Boggild M,Silver N,White R

更新日期：2011-04-01 00:00:00

abstract：:The seasonal occurrence of relapses was analysed retrospectively in a group of 53 patients with treated dermatomyositis (DM) or polymyositis (PM). In DM, the incidence of both myositic and cutaneous relapses was highest in summer whereas in the PM group relapses was more evenly distributed throughout the seasons but l...

journal_title：Journal of neurology

authors： Phillips BA,Zilko PJ,Garlepp MJ,Mastaglia FL

更新日期：2002-04-01 00:00:00

abstract：:Small retrospective case series suggest that decompressive hemicraniectomy can be life saving in patients with cerebral venous thrombosis (CVT) and impending brain herniation. Prospective studies of consecutive cases are lacking. Thus, a single centre, prospective study was performed. In 2006 we adapted our protocol f...

journal_title：Journal of neurology

authors： Zuurbier SM,Coutinho JM,Majoie CB,Coert BA,van den Munckhof P,Stam J

更新日期：2012-06-01 00:00:00

abstract：:Horizontal eye-movement responses of four patients with Alzheimer-type dementia were recorded using the infrared oculographic technique. Abnormally frequent saccadic intrusions occurred during the fixation and slow, smooth pursuit tasks in all four patients. Saccadic intrusions have previously been reported in the lit...

journal_title：Journal of neurology

authors： Jones A,Friedland RP,Koss B,Stark L,Thompkins-Ober BA

更新日期：1983-01-01 00:00:00

abstract：:Acanthocytosis occurs because of ultrastructural abnormalities of the erythrocyte membranous skeleton resulting in reduced membrane fluidity. At least three hereditary neurological conditions are associated with it, although as yet the pathogenesis of the neurological features is unknown. In abetalipoproteinaemia, an ...

journal_title：Journal of neurology

authors： Stevenson VL,Hardie RJ

更新日期：2001-02-01 00:00:00

abstract：:This study aimed at identifying gender-specific differences in stroke knowledge, stroke risk perception and the educational effects of a multimodal educational intervention. We performed computer-assisted telephone surveys among an average sample of 500 members of the general public (44.0% male, 56.0% female), before ...

journal_title：Journal of neurology

authors： Marx JJ,Klawitter B,Faldum A,Eicke BM,Haertle B,Dieterich M,Nedelmann M

更新日期：2010-03-01 00:00:00

abstract：:Sensory trick may relieve dystonic symptoms in patients with idiopathic cervical dystonia (CD). We investigated the patterns of brain functional MRI (fMRI) during resting state, sensory trick simulation and sensory trick imagination in CD patients both with and without an effective sensory trick. We recruited 17 CD pa...

journal_title：Journal of neurology

authors： Sarasso E,Agosta F,Piramide N,Bianchi F,Butera C,Gatti R,Amadio S,Del Carro U,Filippi M

更新日期：2020-04-01 00:00:00

abstract：:We report two adult Japanese sisters with L-2-hydroxy-glutaric aciduria (acidemia), both of whom were much older (aged 57, 47 years old) than previously reported patients (from neonate to 44 years old), and who presented with differing severity. Magnetic resonance imaging revealed typical subcortical white matter lesi...

journal_title：Journal of neurology

authors： Fujitake J,Ishikawa Y,Fujii H,Nishimura K,Hayakawa K,Inoue F,Terada N,Okochi M,Tatsuoka Y

更新日期：1999-05-01 00:00:00

abstract：:The cause of idiopathic intracranial hypertension (IIH) remains unknown, and no consensus exists on how patients should be monitored and treated. Acetazolamide is a common treatment but has never been examined in a randomised controlled trial. The objectives of this pilot trial are to prospectively evaluate the use of...

journal_title：Journal of neurology

authors： Ball AK,Howman A,Wheatley K,Burdon MA,Matthews T,Jacks AS,Lawden M,Sivaguru A,Furmston A,Howell S,Sharrack B,Davies MB,Sinclair AJ,Clarke CE

更新日期：2011-05-01 00:00:00

abstract：:We investigated the muscle strength and motor unit (MU) territory of five patients with postpolio syndrome (PPS), six stable patients with prior poliomyelitis, and five healthy volunteers. The MU territory was assessed by measuring amplitudes of motor unit potentials (MUPs) recorded by the macro EMG technique. The inv...

journal_title：Journal of neurology

authors： Ivanyi B,Ongerboer de Visser BW,Nelemans PJ,de Visser M

更新日期：1994-12-01 00:00:00

abstract：:We report a rare association of spinocerebellar ataxia and motor neuron disease (MND) in a woman with genetically confirmed SCA2 who subsequently developed a rapidly progressive and fatal form of MND. Considering the rarity of these two neurological conditions, it is interesting to note that the concomitant occurrence...

journal_title：Journal of neurology

authors： Nanetti L,Fancellu R,Tomasello C,Gellera C,Pareyson D,Mariotti C

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Adequate cerebral blood flow (CBF) is mainly governed by neurovascular coupling (NC) which adapts local CBF to underlying cortical activity,and cerebral autoregulation (CA)that tends to maintain constant CBF despite changes in arterial blood pressure (BP). Since it was suggested that resistance vessels play ...

journal_title：Journal of neurology

authors： Azevedo E,Rosengarten B,Santos R,Freitas J,Kaps M

更新日期：2007-02-01 00:00:00

abstract：:Dementia is reversible in a minority of patients, and these should be diagnosed but without subjecting the majority with irreversible disease to an excessive set of investigations. Should a battery of ancillary investigations be performed routinely in dementia? Or can these tests be carried out as clinically indicated...

journal_title：Journal of neurology

authors： van Crevel H,van Gool WA,Walstra GJ

更新日期：1999-02-01 00:00:00

abstract：:Little is known about the pattern of subacute cognitive domain impairments after ischaemic stroke, nor the temporal evolution of such impairments. Our objective was to investigate the pattern of cognitive impairment in different neuropsychological domains up to a year after ischaemic stroke. We included prospectively ...

journal_title：Journal of neurology

authors： Hurford R,Charidimou A,Fox Z,Cipolotti L,Werring DJ

更新日期：2013-01-01 00:00:00

abstract：:Hearing deficits associated with cognitive impairment have attracted much recent interest, motivated by emerging evidence that impaired hearing is a risk factor for cognitive decline. However, dementia and hearing impairment present immense challenges in their own right, and their intersection in the auditory brain re...

journal_title：Journal of neurology

authors： Hardy CJ,Marshall CR,Golden HL,Clark CN,Mummery CJ,Griffiths TD,Bamiou DE,Warren JD

更新日期：2016-11-01 00:00:00