Abstract：
:The seasonal occurrence of relapses was analysed retrospectively in a group of 53 patients with treated dermatomyositis (DM) or polymyositis (PM). In DM, the incidence of both myositic and cutaneous relapses was highest in summer whereas in the PM group relapses was more evenly distributed throughout the seasons but lowest in summer. The present findings suggest that environmental factors such as intercurrent infections and light exposure may be involved in reactivating the disease process and causing relapses in DM but less so in PM. Further prospective studies are needed to assess the role of environmental factors in the initiation and reactivation of the inflammatory myopathies.
journal_name
J Neuroljournal_title
Journal of neurologyauthors
Phillips BA,Zilko PJ,Garlepp MJ,Mastaglia FLdoi
10.1007/s004150200036keywords:
subject
Has Abstractpub_date
2002-04-01 00:00:00pages
441-4issue
4eissn
0340-5354issn
1432-1459journal_volume
249pub_type
杂志文章abstract：:A complex neurological syndrome, which rapidly appeared in a 54-year-old woman, created strong diagnostic difficulties. In fact, while the carotid-angiography was negative and CSF not significant, the scintigraphy suggested a multifocal metastatic or infarctual pathology. The CT scan easily allowed us to resolve the d...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/BF00313384
更新日期：1981-01-01 00:00:00
abstract：:A 57-year-old male was repeatedly admitted to hospital because of complex neurological symptoms, including radicular pain, disturbance of micturition, seizures, and severely impaired mental state. The diagnosis was encephalomyeloradiculitis possibly of viral origin, and treatment with immunosuppressants was initiated....
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/BF00314303
更新日期：1988-01-01 00:00:00
abstract：:Gait variability has potential utility as a predictive measure of dysfunction in Parkinson's disease (PD). Current understanding implicates non-dopaminergic pathways. This study investigated the explanatory characteristics of gait variability in PD on and off medication under single and dual task conditions. Fifty peo...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-010-5789-8
更新日期：2011-04-01 00:00:00
abstract：:Movement-associated cortical potentials (MP) associated with thumb-opposition or fist-clenching were studied in 20 patients with unilateral cerebral lesions and in 8 healthy subjects. MP was abnormal in 16 patients. The most frequent abnormality was an attenuation of the N component or readiness potential, recorded on...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/BF00312541
更新日期：1975-07-02 00:00:00
abstract：:REM sleep behavior disorder (RBD) is known to be observed more frequently in patients with an α-synucleinopathy such as Parkinson's disease (PD) than in the general population. The precise prevalence of RBD in Japanese PD patients is not known. Therefore, we investigated the prevalence and the clinical characteristics...
journal_title：Journal of neurology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00415-011-6386-1
更新日期：2012-08-01 00:00:00
abstract：BACKGROUND:Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that still lacks reliable diagnostic biomarkers. This study aims to evaluate the diagnostic and prognostic potential of CSF total Tau (t-Tau), phospho-Tau (p-Tau) and p-Tau/t-Tau ratio in ALS patients using CSF neurofilament light (NFL)...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-018-9008-3
更新日期：2018-10-01 00:00:00
abstract：:Our knowledge of the vestibular sensory system, its functional significance for gaze and posture stabilization, and its capability to ensure accurate spatial orientation perception and spatial navigation has greatly benefitted from experimental approaches using a variety of vertebrate species. This review summarizes t...
journal_title：Journal of neurology
pub_type： 杂志文章,评审
doi：10.1007/s00415-015-7909-y
更新日期：2016-04-01 00:00:00
abstract：:Production of reactive oxygen species after cerebral blood flow disruption may enhance tissue damage through multiple molecular pathways. Changes in nitric oxide (NO) metabolism and oxidative stress status were investigated in 47 patients with ischemic stroke by measuring plasma nitric oxide (NO) and peroxynitrite (ON...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-007-0700-y
更新日期：2008-01-01 00:00:00
abstract：:Stavudine (2',3'-didehydro-3'deoxythymidine) is a pyrimidine analogue that may be of great value in combination antiretroviral therapy (ART) for treating patients infected with human immunodeficiency virus type 1 (HIV-1). We assessed potential neurotoxic side effects by comparing peripheral nerve function in patients ...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s004150050336
更新日期：1999-03-01 00:00:00
abstract：:This study aimed to elucidate the natural history of senile myoclonic epilepsy, a type of myoclonic epilepsy associated with Alzheimer's disease in adult Down syndrome patients. Twelve Down syndrome patients over the age of 40 years with myoclonic epilepsy and Alzheimer's disease underwent clinical, neuropsychological...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-014-7376-x
更新日期：2014-08-01 00:00:00
abstract：:Prolonged clinico-immunological observation of 85 patients with definite multiple sclerosis (MS) was performed in order to elucidate the connections between the clinical and immune state. A battery of immunological investigations was performed, including estimation of T-cell subpopulations in blood and cerebrospinal f...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/BF00919713
更新日期：1994-07-01 00:00:00
abstract：OBJECTIVE:To determine the response to treatment and the long-term outcome of patients with the antisynthetase syndrome associated with anti-Jo-1-antibodies. PATIENTS AND METHODS:A total of 12 patients with histologically proven myositis and anti-Jo-1-autoantibodies were evaluated over a mean follow-up period of 66.4 ...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-004-0449-5
更新日期：2004-07-01 00:00:00
abstract：:Oculomotor dysfunction in Parkinson's disease (PD) is mainly characterized by a fragmentation of memory-guided gaze shifts (target is reached by several hypometric saccades). Since this phenomenon can also be observed in normal subjects, we scrutinized its pathophysiological significance in PD patients. We recorded ho...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-002-0691-7
更新日期：2002-06-01 00:00:00
abstract：:Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are often clinically confused with each other. Moreover, the discrepancy between clinical and pathological diagnoses of CBD and PSP are still controversial. We report here two atypical cases of PSP and CBD. A 73-year old woman was admitted with r...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-005-0718-y
更新日期：2005-06-01 00:00:00
abstract：:Several studies have reported infection as a possible risk factor for cervical artery dissection (CAD). We retrospectively analyzed several inflammatory parameters of CAD patients with the aim of detecting differences between spontaneous (n = 25) and traumatic (n = 18) CAD. In this case-control study, we observed sign...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-006-0109-z
更新日期：2006-06-01 00:00:00
abstract：:Corticobasal degeneration (CBD) was first described by Rebeiz et al. in 1967, and was called corticodentatonigral degeneration with neuronal achromasia [1]. Since then, our knowledge of the clinical features and underlying tau pathology has grown tremendously. Clinical antemortem diagnosis of CBD pathology remains cha...
journal_title：Journal of neurology
pub_type： 历史文章,杂志文章
doi：10.1007/s00415-017-8644-3
更新日期：2018-02-01 00:00:00
abstract：:A total of 15 patients affected by idiopathic dystonia (7 with generalized and 8 with focal or segmental dystonia) were subjected to therapy with bromocriptine at low doses, pimozide and trihexyphenidyl. The symptoms were evaluated by giving a progressive score in relation to the intensity of the dystonic symptom to e...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/BF00313391
更新日期：1982-01-01 00:00:00
abstract：:The number of dementia patients requesting euthanasia in the Netherlands has increased over the past five years. The issue is highly controversial. In this contribution we discuss some of the main arguments: the nature of suffering, the voluntariness of the request and the role of the physician. We argue that society ...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-016-8095-2
更新日期：2016-07-01 00:00:00
abstract：:We investigated the muscle strength and motor unit (MU) territory of five patients with postpolio syndrome (PPS), six stable patients with prior poliomyelitis, and five healthy volunteers. The MU territory was assessed by measuring amplitudes of motor unit potentials (MUPs) recorded by the macro EMG technique. The inv...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/BF00920572
更新日期：1994-12-01 00:00:00
abstract：:The effect of furosemide (Lasix) therapy on a standardized experimental cerebral edema, induced in rats by applying a cooling stamp to the right side of the skull over the right coronal suture by means of a stereotactic instrument, was examined. The hemispherically separated water and electrolyte contents of the brain...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/BF00705536
更新日期：1979-05-02 00:00:00
abstract：:Sexuality in patients with amyotrophic lateral sclerosis (ALS) has received little attention so far. Although sexual function is not directly affected by the disease process, several patients have reported problems within their sexual relationship. We performed a questionnaire survey to ascertain the extent and clinic...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-004-0351-1
更新日期：2004-04-01 00:00:00
abstract：:Elevated intracranial intravenous pressure is not routinely measured in clinical practice. Indirect evidence of increased venous pressure is reflected in the size change of the cerebral sinuses and the presence of venous infarctions. The purpose of this study is to evaluate the role of brain perfusion venous time-dens...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-011-5955-7
更新日期：2011-08-01 00:00:00
abstract：:A 15-year-old boy with Tourette's syndrome exhibited severe involuntary self-mutilatory behavior. While clonidine effectively controlled the motor and phonic tics, it failed to ameliorate the self-mutilatory behavior. Administration of oxycodone (50 mg/day) combined with clonidine produced a dramatic reduction in the ...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/BF00314429
更新日期：1986-06-01 00:00:00
abstract：:The International Cooperative Ataxia Rating Scale (ICARS) is a 100-point semiquantitative scale designed primarily to assess cerebellar dysfunction. However, little is known of the metric properties of this scale. We assessed the ICARS by rating the severity of cerebellar dysfunction in 27 patients with spinocerebella...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-006-0310-0
更新日期：2007-06-01 00:00:00
abstract：:Postpartum lower limb motor and/or sensory deficit is an uncommon obstetrical complication. We aimed to identify its incidence, etiology, and precipitating factors, as well as the neurological prognosis by retrospectively analyzing the successive neurological evaluations, electrophysiological, and MRI data from all th...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-016-8388-5
更新日期：2017-03-01 00:00:00
abstract：:This review summarizes topical papers from the fields of neuro-ophthalmology and neuro-otology published from August 2013 to February 2015. The main findings are: (1) diagnostic criteria for pseudotumor cerebri have been updated, and the Idiopathic Intracranial Hypertension Treatment Trial evaluated the efficacy of ac...
journal_title：Journal of neurology
pub_type： 杂志文章,评审
doi：10.1007/s00415-015-7825-1
更新日期：2015-12-01 00:00:00
abstract：:Fifteen patients with Sneddon's syndrome presenting since 1979 were re-examined. After a neurological examination, an orienting test of mental ability as well as an electroencephalogram were performed in all patients. In 10 of the 15 patients computed tomography of the brain was performed, too. Preceding reports and t...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/BF00314215
更新日期：1989-01-01 00:00:00
abstract：OBJECTIVE:To identify factors that impact on the ability of patients with multiple sclerosis (MS) to remain in work in order to make recommendations for future clinical management. METHODS:Cross-sectional studies using qualitative (phase one) and quantitative (phase two) methods. In phase one, 62 patients were intervi...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-005-0765-4
更新日期：2005-08-01 00:00:00
abstract：:It is now 10 years since the first report of mutations in the presenilin genes that were deterministic for familial autosomal dominant Alzheimer's disease. The most common of these mutations occurs in the presenilin-1 gene (PSEN1) located on chromosome 14. In the ensuing decade, more than 100 PSEN1 mutations have been...
journal_title：Journal of neurology
pub_type： 杂志文章,评审
doi：10.1007/s00415-005-0019-5
更新日期：2006-02-01 00:00:00
abstract：OBJECTIVE:Spinal and bulbar muscular atrophy (SBMA) is caused by an abnormal expansion of the CAG repeat in the androgen receptor gene. This study aimed to systematically phenotype a German SBMA cohort (n = 80) based on laboratory markers for neuromuscular, metabolic, and endocrine status, and thus provide a basis for ...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-018-8790-2
更新日期：2018-05-01 00:00:00
