Abstract:
:A total of 15 patients affected by idiopathic dystonia (7 with generalized and 8 with focal or segmental dystonia) were subjected to therapy with bromocriptine at low doses, pimozide and trihexyphenidyl. The symptoms were evaluated by giving a progressive score in relation to the intensity of the dystonic symptom to each of the body segments involved by the dystonia. Bromocriptine did not significantly modify the dystonia. Pimozide showed a slight nonsignificant improvement of the dystonic symptoms. Trihexyphenidyl was effective in the generalized dystonias, in agreement with previous reports in the literature. The variation in the pharmacological results could be due to the diversity of the dystonic syndromes, which comprise cases that are different in age at onset, site of dystonic symptoms, and evolution.
journal_name
J Neuroljournal_title
Journal of neurologyauthors
Girotti F,Scigliano G,Nardocci N,Angelini L,Broggi G,Giovannini P,Caraceni Tdoi
10.1007/BF00313391subject
Has Abstractpub_date
1982-01-01 00:00:00pages
239-47issue
4eissn
0340-5354issn
1432-1459journal_volume
227pub_type
杂志文章abstract:BACKGROUND AND PURPOSE:Stratification of patients with transient ischemic attack (TIA) or ischemic stroke (IS) by risk of recurrent stroke can contribute to optimized secondary prevention. We therefore aimed to assess cardiovascular risk factor profiles of consecutive patients hospitalized with TIA/IS to stratify the r...
journal_title:Journal of neurology
pub_type: 杂志文章
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更新日期:2007-11-01 00:00:00
abstract::Intravenous immunoglobulins (IVIg) are effective for treating chronic inflammatory demyelinating polyneuropathy (CIDP), although treatment needs are variable and need to be individualized. Dose and frequency requirements are not currently predictable in advance. In Guillain-Barré syndrome, IVIg interpatient pharmacoki...
journal_title:Journal of neurology
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更新日期:2013-08-01 00:00:00
abstract::We describe three patients in whom an isolated sixth nerve palsy was the only clinical symptom or sign of multiple sclerosis (MS). Data were collected prospectively over 6 years on these three patients, who showed no other signs of brainstem dysfunction or prior symptoms; in addition. Retrospective analysis of all pat...
journal_title:Journal of neurology
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更新日期:2000-09-01 00:00:00
abstract::Sensory trick may relieve dystonic symptoms in patients with idiopathic cervical dystonia (CD). We investigated the patterns of brain functional MRI (fMRI) during resting state, sensory trick simulation and sensory trick imagination in CD patients both with and without an effective sensory trick. We recruited 17 CD pa...
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abstract:BACKGROUND:Recently, therapeutic attempts to control motor choreatic hyperkinesia of Huntington's disease (HD) by means of pallidal deep brain stimulation (Gp-DBS) were successful. With respect to the clinical effects of Gp-DBS in juvenile hypokinetic-rigid HD (jHD; Westphal variant), only one single-case has been repo...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/s00415-018-8880-1
更新日期:2018-07-01 00:00:00
abstract::Neuropsychological deficits and the relationship to brain pathology were examined in 13 primary progressive (PP) and 12 secondary progressive (SP) multiple sclerosis patients with a similar duration of the progressive phase and comparable physical disability. A battery of neuropsychological tests to assess attention, ...
journal_title:Journal of neurology
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doi:10.1007/pl00007804
更新日期:2000-02-01 00:00:00
abstract::Three cases of Fahr's syndrome are described. All patients had disturbances of calcium metabolism and had had a meningoencephalitis in childhood. It is suggested that gliovascular changes, induced by cerebral inflammation, can later facilitate the occurrence of calcification of the striopallidodentate system when abno...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313985
更新日期:1986-02-01 00:00:00
abstract::The occurrence of spontaneous internal carotid or vertebral artery dissection after childbirth remains rare. To our knowledge, seven cases of arterial dissection in the postpartum period have been described in the literature as single case reports. We report four additional cases of internal carotid and vertebral arte...
journal_title:Journal of neurology
pub_type: 杂志文章,评审
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更新日期:1999-08-01 00:00:00
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更新日期:2010-05-01 00:00:00
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更新日期:2006-02-01 00:00:00
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journal_title:Journal of neurology
pub_type: 杂志文章
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更新日期:2001-06-01 00:00:00
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journal_title:Journal of neurology
pub_type: 杂志文章
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更新日期:2016-03-01 00:00:00
abstract::A 73-year-old woman presented with multifocal cerebral dysfunction of 1 month's duration. Cranial CT scanning revealed unusual widespread abnormalities. Brain biopsy showed amyloid angiopathy affecting vessels in the meninges and cerebral cortex, with associated granulomatous angiitis. There was no clinical evidence o...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314491
更新日期:1988-09-01 00:00:00
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journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313718
更新日期:1984-01-01 00:00:00
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journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314606
更新日期:1975-06-09 00:00:00
abstract::A general scheme of analysis for the investigation of minute calcification is presented. After low temperature ashing, the samples are subjected to chemical, structural and morphological study, using atomic absorption spectrometry, infrared spectrometry, X-ray diffraction and scanning electron microscopy. Details abou...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00312479
更新日期:1977-06-13 00:00:00
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journal_title:Journal of neurology
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doi:10.1007/s00415-020-09830-3
更新日期:2020-08-01 00:00:00
abstract::Collective evidence supports the notion that multiple sclerosis is principally an autoimmune disease. Much of it stems from models of experimental autoimmune encephalomyelitis, generated by inoculation of animals with central nervous system antigens such as MBP, PLP, S100 and MOG or peptides thereof. Different ways of...
journal_title:Journal of neurology
pub_type: 杂志文章,评审
doi:10.1007/s00415-005-5006-3
更新日期:2005-11-01 00:00:00
abstract::Behçet's disease is a multisystem inflammatory disorder with unknown aetiology. It is a disease of young adults with a more severe course in males subjects. Its prevalence is high in the Mediterranean basin and Japan and has been linked with human leucocyte antigen B5 (HLA-B5) in those countries. According to the diag...
journal_title:Journal of neurology
pub_type: 杂志文章,评审
doi:10.1007/s004150050205
更新日期:1998-04-01 00:00:00
abstract::Among the hereditary cerebellar ataxias (CAs), there are at least 36 different forms of autosomal dominant cerebellar ataxia (ADCAs), 20 autosomal recessive cerebellar ataxias (ARCAs), two X-linked ataxias, and several forms of ataxia associated with mitochondrial defects. Despite the steady increase in the number of ...
journal_title:Journal of neurology
pub_type: 杂志文章,评审
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更新日期:2014-09-01 00:00:00
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journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/s00415-004-0272-z
更新日期:2004-01-01 00:00:00
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journal_title:Journal of neurology
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doi:10.1007/s00415-010-5780-4
更新日期:2011-03-01 00:00:00
abstract::Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a common autoimmune encephalitis presenting with psychosis, dyskinesias, autonomic dysfunction and seizures. The underlying autoantibodies against the NR1 subunit are directly pathogenic by disrupting synaptic NMDAR currents. However, antibody titers correlate...
journal_title:Journal of neurology
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abstract::The type and frequency of neurological manifestations of Behçet's disease (BD) vary with ethnicity. We analyzed the neurological manifestations of BD in Japanese patients. All patients undergoing treatment at one of the two Yokohama City University hospitals from July 1991 to December 2007 and who fulfilled the Japane...
journal_title:Journal of neurology
pub_type: 杂志文章,多中心研究
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更新日期:2010-06-01 00:00:00
abstract::Muscle samples obtained in patients with different neuromuscular diseases were stored at 0 degree C for periods of 6-12h and were subsequently frozen for histochemical processing. Compared to reference samples which had been immediately frozen, the individual test sections displayed different degrees of swelling of th...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313934
更新日期:1984-01-01 00:00:00
abstract::Polysomnography (PSG) is considered the gold standard for diagnosis of non-rapid eye movement (NREM) parasomnias, however its diagnostic yield has been rarely reported. We aimed to assess the diagnostic value of polysomnography in different categories of patients with suspected NREM parasomnia and define variables tha...
journal_title:Journal of neurology
pub_type: 杂志文章
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更新日期:2015-02-01 00:00:00
abstract::The effects of left- and right-sided hemispheric brain infarction on variability in circadian blood pressure and cardiovascular measures were investigated in 35 patients to test for asymmetry of the sympathetic consequences of stroke. No significant differences regarding age, size of infarction or extent and frequency...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00878874
更新日期:1995-05-01 00:00:00
abstract::The United Nations High Commissioner for Refugees (UNHCR) recognizes 43.7 million forcibly displaced persons and asylum seekers due to conflict and persecution worldwide. Neurological disorders have rarely been described in displaced persons but likely pose a significant burden of disease. We describe the disease spec...
journal_title:Journal of neurology
pub_type: 杂志文章
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更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Multiple sclerosis (MS) is an autoimmune, demyelinating disease of the central nervous system. The treatment of MS has always been a focus of neurological research. To date, the US Food and Drug Administration has approved 15 medications for modifying the course of multiple sclerosis. In this study, we exami...
journal_title:Journal of neurology
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更新日期:2020-12-01 00:00:00
abstract::Isolated floccular infarction is extremely rare, and impairments of the vestibulo-ocular reflex (VOR) have not been explored in humans with isolated floccular lesions. The purpose of this study was to examine and report selective impairment of VOR in response to high acceleration using head impulse in a patient with i...
journal_title:Journal of neurology
pub_type: 杂志文章
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更新日期:2013-06-01 00:00:00