Abstract：
:Dementia is reversible in a minority of patients, and these should be diagnosed but without subjecting the majority with irreversible disease to an excessive set of investigations. Should a battery of ancillary investigations be performed routinely in dementia? Or can these tests be carried out as clinically indicated? Three arguments are important to answer this question. (a) Reversible dementia is rare: about 1% of cases. (b) If the clinical criteria for diagnosing primary degenerative disease are used consistently, the results of investigations can be predicted with sufficient accuracy, except those of blood tests. (c) Treatment of reversible dementia has the best results in its most frequent causes: depression and drug intoxication; however, treatment of medical and surgical causes of dementia may also be effective. Based on these three considerations, we propose the following guideline in the setting of a memory clinic: to perform blood tests in every patient with dementia, but also to perform other tests, such as electroencephalography (EEG) and computed tomography (CT), as clinically indicated.
journal_name
J Neuroljournal_title
Journal of neurologyauthors
van Crevel H,van Gool WA,Walstra GJdoi
10.1007/s004150050311keywords:
subject
Has Abstractpub_date
1999-02-01 00:00:00pages
73-8issue
2eissn
0340-5354issn
1432-1459journal_volume
246pub_type
杂志文章,评审abstract：:This observational study examined the outcome of two different therapeutic strategies in the treatment of chronic neuropathic pain by including pregabalin (PGB) as mono- or add-on therapy in one of two treatment options. Patients with a pain score of > or =4, refractory to usual care for neuropathic pain for at least ...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-010-5504-9
更新日期：2010-08-01 00:00:00
abstract：OBJECTIVE:Patients with classic ataxia-telangiectasia (A-T) generally die in the second or third decade of life. Clinical descriptions of A-T tend to focus on the symptoms at presentation. However, during the course of the disease, other symptoms and complications emerge. As long-term survivors with classic A-T develop...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-019-09641-1
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abstract：OBJECTIVE:To report the clinical features and long-term outcome of 22 newly diagnosed paraneoplastic patients with GABAB receptor antibodies (GABABR-Abs). METHODS:Retrospective clinical study of CSF-confirmed cases of GABABR-Abs encephalitis. RESULTS:We identified 22 patients (4 female) with GABABR-Abs, with a median...
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pub_type： 杂志文章
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更新日期：2019-01-01 00:00:00
abstract：:Recent years have seen substantial news and updates in the genetics and diagnosis of schwannomas, even a new hereditary disease with schwannomas; Schwannomatosis has been defined. These developments have consequently led to better evaluation of the incidence of schwannomas. Although there has also been progress in the...
journal_title：Journal of neurology
pub_type： 杂志文章,评审
doi：10.1007/s00415-006-0347-0
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abstract：:It is now 10 years since the first report of mutations in the presenilin genes that were deterministic for familial autosomal dominant Alzheimer's disease. The most common of these mutations occurs in the presenilin-1 gene (PSEN1) located on chromosome 14. In the ensuing decade, more than 100 PSEN1 mutations have been...
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doi：10.1007/s00415-005-0019-5
更新日期：2006-02-01 00:00:00
abstract：:Postpartum lower limb motor and/or sensory deficit is an uncommon obstetrical complication. We aimed to identify its incidence, etiology, and precipitating factors, as well as the neurological prognosis by retrospectively analyzing the successive neurological evaluations, electrophysiological, and MRI data from all th...
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pub_type： 杂志文章
doi：10.1007/s00415-016-8388-5
更新日期：2017-03-01 00:00:00
abstract：:Migraine is a common and disabling nervous system disease with a significant genetic predisposition. The sex hormones play an important role in the pathogenesis of migraine. However, the conclusions of the previous genetic relation studies are conflicting. The aim of this study is to determine whether variants in gene...
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pub_type： 杂志文章
doi：10.1007/s00415-016-8321-y
更新日期：2017-01-01 00:00:00
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journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-020-10279-7
更新日期：2020-10-22 00:00:00
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pub_type： 杂志文章
doi：10.1007/s00415-018-8979-4
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pub_type： 杂志文章,meta分析,评审
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journal_title：Journal of neurology
pub_type： 杂志文章,评审
doi：10.1007/s00415-008-4002-9
更新日期：2008-08-01 00:00:00
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journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-009-0034-z
更新日期：2009-03-01 00:00:00
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journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/BF00319737
更新日期：1991-08-01 00:00:00
abstract：: ...
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pub_type： 信件
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更新日期：2018-12-01 00:00:00
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journal_title：Journal of neurology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00415-010-5768-0
更新日期：2011-03-01 00:00:00
abstract：INTRODUCTION:Two population-based studies of neuromyelitis optica (NMO) in non-white populations provided prevalence rates of 0.32 and 3.1 per 100,000 population. OBJECTIVE:To estimate NMO prevalence in the multiethnic Cuban population by nation-wide case ascertainment. METHODS:The study was conducted from October 1,...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-009-0009-0
更新日期：2009-01-01 00:00:00
abstract：:Spastic paraplegia type 7 (SPG7) is an autosomal recessive form of hereditary spastic paraparesis (ARHSP) caused by mutations in paraplegin, a subunit of an ATP-dependent AAA-protease located within the inner mitochondrial membrane. We have identified a novel paraplegin mutation, c.1047insC, in a non-consanguineous No...
journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-008-0858-y
更新日期：2008-08-01 00:00:00
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journal_title：Journal of neurology
pub_type： 杂志文章
doi：10.1007/s00415-019-09508-5
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journal_title：Journal of neurology
pub_type： 杂志文章,评审
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journal_title：Journal of neurology
pub_type： 杂志文章,评审
doi：10.1007/s004150050205
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pub_type： 临床试验,杂志文章
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journal_title：Journal of neurology
pub_type： 杂志文章
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journal_title：Journal of neurology
pub_type： 杂志文章
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更新日期：2016-06-01 00:00:00
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journal_title：Journal of neurology
pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Journal of neurology
pub_type： 杂志文章
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更新日期：1996-07-01 00:00:00
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