Wide distribution of homologs of Escherichia coli Kdp K+-ATPase among gram-negative bacteria.

Abstract:

:We used Southern blotting to screen a variety of bacterial genes for homology to the kdp genes of Escherichia coli, genes that encode an ATP-driven K+ transport system. We found that most enterobacteria have sequences homologous to those of the three kdp structural genes and the kdpD regulatory gene. A number of distantly related species, including some cyanobacteria, have sequences homologous to those of the structural genes but not the regulatory gene. In all cases only a single region of homology was found. These results suggest that ATP-driven transport systems similar to the Kdp system in structure and regulation are found in many enteric organisms. In other gram-negative organisms, the ATPase is more divergent, retaining good homology at the DNA level only to the highly conserved phosphorylated subunit of the ATPase.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Walderhaug MO,Litwack ED,Epstein W

doi

10.1128/jb.171.2.1192-1195.1989

subject

Has Abstract

pub_date

1989-02-01 00:00:00

pages

1192-5

issue

2

eissn

0021-9193

issn

1098-5530

journal_volume

171

pub_type

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