Abstract：
AIM:To evaluate the risk of urinary tract infections (UTI) in subjects with newly diagnosed type 2 diabetes mellitus (T2DM). METHODS:Subjects aged ≥18years and diagnosed with T2DM between 1/1/10 and 12/31/10 were identified using the MarketScan® databases, which are representative of the commercially insured US population and those with both Medicare and supplemental coverage. The index date was the first T2DM diagnosis date in 2010 (date randomly selected for those without T2DM). Subjects without T2DM were matched (1:1) by index date, age, gender, urban/rural location, and region. All subjects had continuous enrollment for 12 months before (baseline) and after (follow-up) the index date. UTI diagnosis was defined using ICD-9-CM codes. Measurements of glycemic control and body weight were not available. An adjusted logistic regression model assessed the likelihood of UTI. RESULTS:A total of 89,790 matched pairs were selected. During follow-up, a UTI diagnosis was more common in subjects with T2DM than without T2DM (9.4% vs. 5.7%; p<0.0001). Recurrence of UTI was also more likely with T2DM (1.6% vs. 0.6%; p<0.0001). In a logistic regression, subjects with T2DM had a greater likelihood of UTI during follow up (adjusted odds ratio [OR]=1.54 [95% CI: 1.47-1.60]). This relationship remained after stratifying by gender. CONCLUSION:Subjects with T2DM were more likely to experience a UTI and recurrent UTIs than subjects without T2DM during follow-up.
journal_name
J Diabetes Complicationsjournal_title
Journal of diabetes and its complicationsauthors
Fu AZ,Iglay K,Qiu Y,Engel S,Shankar R,Brodovicz Kdoi
10.1016/j.jdiacomp.2014.06.009subject
Has Abstractpub_date
2014-11-01 00:00:00pages
805-10issue
6eissn
1056-8727issn
1873-460Xpii
S1056-8727(14)00189-5journal_volume
28pub_type
杂志文章abstract：:Radial pulse spectrum has been shown to correlate with coronary stenosis in patients with type 2 diabetes mellitus (T2DM). In academia, it has not been demonstrated that the radial artery pulse spectrum is an independent risk factor for major adverse cardiovascular events (MACE), including myocardial infarction, strok...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/j.jdiacomp.2018.10.009
更新日期：2019-02-01 00:00:00
abstract：AIMS:The Haptoglobin (HP) 2-2 genotype increases cardiovascular diabetes complication incidence. In type 1 diabetes, HP 2-2 also predicts declining kidney function and end-stage renal disease. We investigated whether HP 2-2 predisposes to cardio-renal mortality, while considering other causes of death as competing risk...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/j.jdiacomp.2015.11.011
更新日期：2016-03-01 00:00:00
abstract：OBJECTIVE:Type 1 diabetes (T1DM) is a pro-inflammatory state characterized by high C-reactive protein (CRP) levels. However, there is a paucity of data examining the role of CRP in promoting the pro-inflammatory state of diabetes. Thus, we examined the pro-inflammatory effects of human CRP using spontaneously diabetic ...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/j.jdiacomp.2012.03.020
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to compare the prevalence of diabetes-related comorbidities in Asian Americans to the prevalence in other racial and ethnic groups in the United States using data from the 2001 Behavioral Risk Factor Surveillance System (BRFSS). METHODS:The BRFSS is a population-based telephone surv...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/j.jdiacomp.2004.08.003
更新日期：2005-03-01 00:00:00
abstract：AIMS:To investigate the effect of a single nucleotide polymorphism (SNP) in transmembrane protein 182 (TMEM182) on the risk of having central obesity and the related phenotype. METHODS:In total, 2141 subjects with central obesity (n = 827) and normal controls (n = 1314) were included. The most strongly associated SNPs...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/j.jdiacomp.2020.107732
更新日期：2020-12-01 00:00:00
abstract：OBJECTIVE:Increased arterial stiffness is a marker of atherosclerosis and is recognised early in the course of type 2 diabetes mellitus (T2DM). Matrix metalloproteinases (MMP) and their tissue inhibitors (TIMP) are a family of proteolytic enzymes which are essential for the structure and function of large arteries. In ...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/j.jdiacomp.2008.10.004
更新日期：2010-01-01 00:00:00
abstract：AIMS:To investigate about serum PCT, IL-6 and IL-8 levels and how they are affected by the treatment in diabetic foot patients. METHODS:Fifty patients' blood samples were taken to study ESR and CRP, IL-6, IL-8 and PCT before and at the 14th day of the treatment. RESULTS:The pretreatment results of the 50 patients sho...
journal_title：Journal of diabetes and its complications
pub_type： 临床试验,杂志文章
doi：10.1016/j.jdiacomp.2012.03.018
更新日期：2012-05-01 00:00:00
abstract：AIMS:Compare performances of diabetes risk scores and glycated hemoglobin (HbA1c) to estimate the risk of incident type 2 diabetes mellitus (T2DM) in Northeast Germany. METHODS:We studied 2916 subjects (20 to 81years) from the Study of Health in Pomerania (SHIP) in a 5-year follow-up period. Diabetes risk scores inclu...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/j.jdiacomp.2017.07.016
更新日期：2017-11-01 00:00:00
abstract：AIMS:To estimate prevalence and incidence of auto-immune thyroid disease and thyroid auto-antibodies in an unselected cohort of patients with DM1, including stratification by age, gender and duration of diabetes. METHODS:Patients with T1D visiting our outpatient clinic between 1995 and 2011 were included. We calculate...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/j.jdiacomp.2015.12.027
更新日期：2016-04-01 00:00:00
abstract：AIM:To evaluate the efficacy, safety, and tolerability of multiple doses of ipragliflozin. This novel selective inhibitor of sodium glucose co-transporter 2 is in clinical development for the treatment of patients with type 2 diabetes mellitus (T2DM). METHODS:In a 12-week, multicenter, double-blind, randomized, active...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.jdiacomp.2012.11.005
更新日期：2013-05-01 00:00:00
abstract：:Recommended low-density lipoprotein cholesterol (LDL-C) levels for patients with documented cardiovascular disease (CVD) are <100mg/dL (2.6mmol/l) with further reduction to <70mg/dL (1.8mmol/l) for higher-risk patients. High-intensity statin treatment may halt the progression as well as stabilize and induce regression...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章,评审
doi：10.1016/j.jdiacomp.2014.10.004
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVES:The objectives of this study were to evaluate and to compare the glycemic control of various antidiabetic agents and the role of homocysteine in type 2 diabetes mellitus. RESEARCH DESIGN AND METHODS:Two hundred forty patients with type 2 diabetes mellitus, divided into Groups 1-6 (n=40), received glipizide,...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/j.jdiacomp.2006.09.001
更新日期：2008-03-01 00:00:00
abstract：OBJECTIVE:This study aimed to determine the prevalence of type 2 diabetes mellitus (DM) and impaired fasting glycemia (IFG), identify their associated factors, determine how the prevalence of type 2 DM has changed over 10 years, and assess the awareness and state of control of diabetes in Jordan. METHODS:Data were ana...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/j.jdiacomp.2007.01.004
更新日期：2008-09-01 00:00:00
abstract：:Paecilomyces is a saprophytic soil fungus that is an uncommon human pathogen. We report a diabetic patient who developed an upper lobe pulmonary infection due to Paecilomyces varioti. This pneumonia responded poorly to oral imidazole therapy with ketoconazole. Eventual treatment of the chronic infiltrating process req...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/1056-8727(92)90027-i
更新日期：1992-04-01 00:00:00
abstract：:Although higher levels of hemoglobin A1c (HbA1c) and blood pressure precede the development of nephropathy in Type 1 diabetes (T1DM), the relationship between glycemic control and cardiovascular factors early in the course of diabetes is not clear. We conducted a retrospective study from clinic data for a 1-year perio...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/S1056-8727(03)00031-X
更新日期：2004-07-01 00:00:00
abstract：INTRODUCTION:Diabetic polyneuropathy aetiology is based on oxidative stress generation due to production of reactive oxygen species. Ubiquinone is reduced to ubiquinol and redistributed into lipoproteins, possibly to protect them from oxidation. AIMS:To evaluate the impact of oral ubiquinone in diabetic polyneuropathy...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jdiacomp.2012.04.004
更新日期：2012-07-01 00:00:00
abstract：AIMS:The cardiovascular risk factors and diabetic complications are related to coronary atherosclerosis. However, the evaluation of the prevalence of coronary atherosclerosis based on their accumulation remains to be determined. METHODS:247 consecutive Chinese subjects with type 2 diabetes but without history of coron...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/j.jdiacomp.2015.12.019
更新日期：2016-04-01 00:00:00
abstract：OBJECTIVE:The aim of this study is to investigate the relationship between plasma NH2-terminal pro-brain natriuretic peptide (NT-proBNP) levels and diabetic nephropathy in type 2 diabetic patients. METHODS:The records of 983 patients with type 2 diabetes hospitalized in the Endocrinology and Metabolism Department of P...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/j.jdiacomp.2016.01.017
更新日期：2016-05-01 00:00:00
abstract：AIMS:Using psychological and quality of life assessment tools, we prospectively studied changes in health-related quality of life and emotional well-being in patients who had commenced GLP-1 analogue therapy (exenatide) and compared them with new insulin starters. METHODS:Two matched groups of patients with type 2 dia...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/j.jdiacomp.2011.03.002
更新日期：2011-07-01 00:00:00
abstract：OBJECTIVE:MicroRNAs (miRNAs) have emerged as promising regulators of diabetes mellitus (DM)-induced angiogenic dysfunction in endothelial cells (ECs), but information vis-à-vis the functional roles of distinct miRNAs remain surprisingly scarce. The current study was designed to elucidate the expression and function of ...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/j.jdiacomp.2019.02.001
更新日期：2019-05-01 00:00:00
abstract：:We have previously reported that high glucose stimulates osteopontin (OPN) expression through protein kinase C-dependent pathway, as well as the hexosamine pathway, in cultured rat aortic smooth muscle cells (SMC). The finding prompted us to study in vivo expression of OPN in diabetes mellitus. In the present study, w...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/s1056-8727(01)00189-1
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND:Glomerular hyperfiltration is not able to be detected in clinical practice. We assessed whether hyperfiltration is associated with albuminuria progression among Indigenous Australians at high risk of diabetes and kidney disease to determine its role in kidney disease progression. METHODS:Longitudinal observ...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/j.jdiacomp.2019.02.005
更新日期：2019-05-01 00:00:00
abstract：:Incretin based therapies such as dipeptidyl peptidase-4 inhibitors (DPP-4i) and glucagon-like peptide-1 receptor agonists (GLP-1Ra) are increasingly used for the treatment of Type 2 diabetes mellitus. In clinical practice and in previously performed clinical trials, these agents are often used in combination with othe...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章,meta分析
doi：10.1016/j.jdiacomp.2016.08.018
更新日期：2018-01-01 00:00:00
abstract：:Tolrestat is a well tolerated nonhydantoin aldose reductase inhibitor that has been reported to improve nerve conduction in diabetic animals and humans. Its effects on nerve biochemistry and structure have not been studied in patients with diabetic neuropathy. Patients with advanced diabetic neuropathy treated with lo...
journal_title：Journal of diabetes and its complications
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/1056-8727(93)90041-v
更新日期：1993-07-01 00:00:00
abstract：:Vasomotion, the spontaneous rhythmic contraction exhibited by small arteries and arterioles is dysregulated in patients with diabetic neuropathy. We examined the relationship between Charcot arthropathy and vasomotion at the dorsum of the foot. We studied nine diabetic patients with clinically diagnosed neuropathy and...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/s1056-8727(97)00080-9
更新日期：1998-05-01 00:00:00
abstract：AIM:To evaluate the use of the FINDRISC score in an overweight and obese population to predict glucose status. METHODS:In 651 overweight/obese subjects (M/F: 193/458, age 43±13 y, BMI 38.2±6.1kg/m(2)) glucose status was tested using OGTT and HbA1c. Furthermore, the FINDRISC questionnaire and CT visceral fat (VAT) and ...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/j.jdiacomp.2016.05.004
更新日期：2016-08-01 00:00:00
abstract：AIM:To assess the contribution of β-cell dysfunction and insulin resistance to type 2 diabetes (T2D) in obese and non-obese Chinese people. METHODS:In this cross-sectional study, we recruited 1384 newly diagnosed T2D patients and 1712 healthy controls. Insulin resistance was estimated by homeostasis model assessment o...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/j.jdiacomp.2016.03.001
更新日期：2016-07-01 00:00:00
abstract：AIMS:The Diabetes Complications Severity Index (DCSI) converts diagnostic codes and laboratory results into a 14-level metric quantifying the long-term effects of diabetes on seven body systems. Adoption of the International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) necessitates tran...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/j.jdiacomp.2017.02.018
更新日期：2017-06-01 00:00:00
abstract：:Hypomagnesemia is common in diabetic subjects, and is especially common in poorly controlled diabetes, suggesting that diabetes low serum magnesium status is osmotic diuresis-dependent. To assess the relationship between serum magnesium and HDL-cholesterol concentration adjusted by serum glucose values. We assessed th...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/s1056-8727(00)00127-6
更新日期：2000-09-01 00:00:00
abstract：:The primary aims of this study have been to explore the diagnostic and prognostic significance of Tissue Doppler parameters (TDI), global longitudinal strain (GLS), and blood pressure (BP) pattern in normotensive diabetic patients. METHODS:The study consisted of 121 diabetic patients and 41 healthy subjects. Conventi...
journal_title：Journal of diabetes and its complications
pub_type： 杂志文章
doi：10.1016/j.jdiacomp.2017.07.022
更新日期：2018-01-01 00:00:00
