Hypomagnesemia is linked to low serum HDL-cholesterol irrespective of serum glucose values.

Abstract:

:Hypomagnesemia is common in diabetic subjects, and is especially common in poorly controlled diabetes, suggesting that diabetes low serum magnesium status is osmotic diuresis-dependent. To assess the relationship between serum magnesium and HDL-cholesterol concentration adjusted by serum glucose values. We assessed the serum magnesium levels of 50 controlled (HbA(1c)7.5% and FPG>/=126 mg/dl) type II diabetic patients, 40 subjects with impaired fasting glucose (IFG) (FPG>/=110 mg/dl and <126 mg/dl) and 190 healthy volunteers (FPG<110 mg/dl). Healthy volunteers were required to have normal blood pressure and normal laboratory tests. Subjects in the groups included were matched by age and body mass index (BMI). The average of diabetes duration was of 11.4+/-6.6, and 10.9+/-6.2 years, P=NS, for the controlled and non-controlled diabetic patients, respectively. Thirty (60.0%) controlled diabetic subjects, 58 (52. 7%) non-controlled diabetic patients, 21 (52.5%) subjects with IFG, and 39 (20.5%) healthy volunteers had serum magnesium levels

authors

Guerrero-Romero F,Rodríguez-Morán M

doi

10.1016/s1056-8727(00)00127-6

keywords:

subject

Has Abstract

pub_date

2000-09-01 00:00:00

pages

272-6

issue

5

eissn

1056-8727

issn

1873-460X

pii

S1056-8727(00)00127-6

journal_volume

14

pub_type

杂志文章
  • The 1h post glucose value best predicts future dysglycemia among normal glucose tolerance subjects.

    abstract:AIM:To analyse the OGTT glycemic parameters - fasting, 1h and 2h plasma glucose values singly and in various combinations; with respect to their prediction of future dysglycemia in subjects with normal glucose tolerance (NGT). METHODS:Electronic medical records of individuals who underwent an OGTT between 1991 and 201...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2017.07.017

    authors: Sai Prasanna N,Amutha A,Pramodkumar TA,Anjana RM,Venkatesan U,Priya M,Pradeepa R,Mohan V

    更新日期:2017-11-01 00:00:00

  • Active- and placebo-controlled dose-finding study to assess the efficacy, safety, and tolerability of multiple doses of ipragliflozin in patients with type 2 diabetes mellitus.

    abstract:AIM:To evaluate the efficacy, safety, and tolerability of multiple doses of ipragliflozin. This novel selective inhibitor of sodium glucose co-transporter 2 is in clinical development for the treatment of patients with type 2 diabetes mellitus (T2DM). METHODS:In a 12-week, multicenter, double-blind, randomized, active...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.jdiacomp.2012.11.005

    authors: Fonseca VA,Ferrannini E,Wilding JP,Wilpshaar W,Dhanjal P,Ball G,Klasen S

    更新日期:2013-05-01 00:00:00

  • Patients with type 2 diabetes having higher glomerular filtration rate showed rapid renal function decline followed by impaired glomerular filtration rate: Japan Diabetes Complications Study.

    abstract:AIMS:The Japan Diabetes Complications Study (JDCS), a nation-wide, multicenter, prospective study of patients with type 2 diabetes, reported that hemoglobin A1c (HbA1c), systolic blood pressure, and smoking were risk factors for the onset of macroalbuminuria. This study explored the risk factors for glomerular filtrati...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.jdiacomp.2016.06.020

    authors: Moriya T,Tanaka S,Sone H,Ishibashi S,Matsunaga S,Ohashi Y,Akanuma Y,Haneda M,Katayama S

    更新日期:2017-02-01 00:00:00

  • Mean platelet volume in Type 2 diabetic patients.

    abstract:BACKGROUND:Altered platelet morphology and function have been reported in patients with diabetes mellitus. They are likely to be associated with the pathological processes and increased risk of vascular disease seen in these patients. We aimed to determine the mean platelet volume (MPV) in diabetics compared to nondiab...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/S1056-8727(02)00282-9

    authors: Hekimsoy Z,Payzin B,Ornek T,Kandoğan G

    更新日期:2004-05-01 00:00:00

  • Renal effects of contrast media in diabetic patients undergoing diagnostic or interventional coronary angiography.

    abstract:BACKGROUND:The use of safe iodinated contrast media (CM) to prevent contrast-induced nephropathy (CIN) is an important consideration among renally impaired diabetic patients during coronary angiography. HYPOTHESIS:Diabetic patients with normal or mild renal dysfunction are less likely to receive renal protective measu...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jdiacomp.2006.11.002

    authors: Hardiek KJ,Katholi RE,Robbs RS,Katholi CE

    更新日期:2008-05-01 00:00:00

  • Brain-derived neurotrophic factor correlated with muscle strength in subjects undergoing stationary bicycle exercise training.

    abstract:AIMS:Several central nervous disorders are associated with metabolic syndrome (MetS) and type 2 diabetes. Reduction in brain-derived neurotrophic factor (BDNF) is involved in the mechanism of central nervous dysfunction. BDNF is up-regulated after exercise, but it is not known whether increased BDNF is related to incre...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2015.01.014

    authors: Tsai SW,Chan YC,Liang F,Hsu CY,Lee IT

    更新日期:2015-04-01 00:00:00

  • Prostaglandins and diabetic nephropathy.

    abstract::Abnormalities of renal prostaglandins (PGs) contribute to the pathogenesis of diabetic nephropathy through changes in renal hemodynamics. Our recent studies have demonstrated that urinary excretion ratio of 6-keto-PGF1 alpha (6KF) to TXB2 is decreased in patients with non-insulin-dependent diabetes mellitus (NIDDM). I...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/1056-8727(95)80035-d

    authors: Umeda F,Kuroki T,Nawata H

    更新日期:1995-10-01 00:00:00

  • MiR-126 overexpression inhibits high glucose-induced migration and tube formation of rhesus macaque choroid-retinal endothelial cells by obstructing VEGFA and PIK3R2.

    abstract:AIM:The aims of this study are to investigate the relative regulation between miR-126 and VEGF/PI3K/AKT signaling pathway in retinal vascular endothelial cells. METHODS:Rhesus macaque choroid-retinal endothelial cell line (RF/6A) cells were cultured in high glucose to imitate the conditions occurring in DR. First, we ...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2016.12.004

    authors: Yang WZ,Yang J,Xue LP,Xiao LB,Li Y

    更新日期:2017-04-01 00:00:00

  • Gestational diabetes: differences between the current international diagnostic criteria and implications of switching to IADPSG.

    abstract:AIMS:To highlight the differences between eight international expert panel diagnostic criteria (either current or outdated but in use) for the diagnosis of gestational diabetes mellitus (GDM) and implications of switching to the International Association of Diabetes in Pregnancy Study Groups (IADPSG) criterion. METHOD...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2015.03.006

    authors: Agarwal MM,Dhatt GS,Othman Y

    更新日期:2015-05-01 00:00:00

  • The change in one-hour postload plasma glucose levels, and an analysis of its related factors in abdominally obese Han Chinese men with normal glucose tolerance.

    abstract:OBJECTIVE:This study was to observe the difference in one-hour postload plasma glucose levels and analyze its related factors in abdominally obese men with normal glucose tolerance (NGT). DESIGN:This case-control study included 36 abdominally obese men (waist circumference ≥90 cm) and 31 non-abdominally obese men (wai...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2012.05.022

    authors: Qin CM,Wang R,Yin FZ,Liu B,Ma CM,Lu Q

    更新日期:2012-11-01 00:00:00

  • Cognitive functioning among patients with diabetic foot.

    abstract:AIMS:Using diabetic foot (DF) as an indicator of severe diabetes, we aimed to investigate the cognitive profile of DF patients and the relations between cognitive functioning and both diabetes complications and comorbidities. METHODS:Dementia-free patients with DF aged 30-90 (n=153) were assessed through medical recor...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2014.07.005

    authors: Marseglia A,Xu W,Rizzuto D,Ferrari C,Whisstock C,Brocco E,Fratiglioni L,Crepaldi G,Maggi S

    更新日期:2014-11-01 00:00:00

  • Elevated serum KL-6 concentrations in patients with diabetes mellitus.

    abstract::To clarify the influence of blood glucose level or diabetes mellitus on serum KL-6, a mucin-like glycoprotein, concentrations, they were measured against 176 diabetic subjects, including receiving insulin (INS) group (n=54), oral antidiabetics (OAD) group (n=78), and diet and exercise (D&E) group (n=44). Serum KL-6 co...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/s1056-8727(01)00220-3

    authors: Takahashi T,Takamura K,Sakaue S,Ishii J,Yokouchi H,Nasuhara Y

    更新日期:2002-09-01 00:00:00

  • The effect of radial pulse spectrum on the risk of major adverse cardiovascular events in patients with type 2 diabetes.

    abstract::Radial pulse spectrum has been shown to correlate with coronary stenosis in patients with type 2 diabetes mellitus (T2DM). In academia, it has not been demonstrated that the radial artery pulse spectrum is an independent risk factor for major adverse cardiovascular events (MACE), including myocardial infarction, strok...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2018.10.009

    authors: Chang CW,Liao KM,Chang YT,Wang SH,Chen YC,Wang GC

    更新日期:2019-02-01 00:00:00

  • Albuminuria in normals and essential hypertension.

    abstract::The prevalence and determinants of urinary albumin excretion rate (AER) were assessed in lean and overweight normotensive subjects (NT) and patients with essential hypertension (EH). In NT and EH, the presence of overweight was associated with a significant exacerbation of AER. In the normotensive population, AER was ...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/1056-8727(94)90032-9

    authors: Mimran A,Ribstein J,DuCailar G,Halimi JM

    更新日期:1994-07-01 00:00:00

  • The effect of ubiquinone in diabetic polyneuropathy: a randomized double-blind placebo-controlled study.

    abstract:INTRODUCTION:Diabetic polyneuropathy aetiology is based on oxidative stress generation due to production of reactive oxygen species. Ubiquinone is reduced to ubiquinol and redistributed into lipoproteins, possibly to protect them from oxidation. AIMS:To evaluate the impact of oral ubiquinone in diabetic polyneuropathy...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jdiacomp.2012.04.004

    authors: Hernández-Ojeda J,Cardona-Muñoz EG,Román-Pintos LM,Troyo-Sanromán R,Ortiz-Lazareno PC,Cárdenas-Meza MA,Pascoe-González S,Miranda-Díaz AG

    更新日期:2012-07-01 00:00:00

  • Paecilomyces varioti pneumonia in a patient with diabetes mellitus.

    abstract::Paecilomyces is a saprophytic soil fungus that is an uncommon human pathogen. We report a diabetic patient who developed an upper lobe pulmonary infection due to Paecilomyces varioti. This pneumonia responded poorly to oral imidazole therapy with ketoconazole. Eventual treatment of the chronic infiltrating process req...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/1056-8727(92)90027-i

    authors: Byrd RP Jr,Roy TM,Fields CL,Lynch JA

    更新日期:1992-04-01 00:00:00

  • Peroxisome proliferator-activated receptor gamma polymorphism Pro12Ala is associated with nephropathy in type 2 diabetes.

    abstract:AIM:One putative determinant of diabetic nephropathy is the Pro12Ala (P12A) polymorphism in the gene encoding peroxisome proliferator-activated receptor gamma (PPARgamma). Previous research has found a "protective" role for the A12 allele in association with type 2 diabetes, atherosclerosis, and measures of kidney dama...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2006.02.006

    authors: Pollex RL,Mamakeesick M,Zinman B,Harris SB,Hegele RA,Hanley AJ

    更新日期:2007-05-01 00:00:00

  • Albuminuria rather than glomerular filtration rate is associated with vascular endothelial function in patients with type 2 diabetes.

    abstract:AIMS:Albuminuria and reduced glomerular filtration rate (GFR) are manifestations of diabetic kidney disease and are both shown to be associated with cardiovascular outcomes. However, the differential association of albuminuria and reduced GFR with endothelial dysfunction, an early feature of atherosclerotic vascular da...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2020.107702

    authors: Kakutani Y,Morioka T,Mori K,Yamazaki Y,Ochi A,Kurajoh M,Fukumoto S,Shioi A,Shoji T,Inaba M,Emoto M

    更新日期:2020-12-01 00:00:00

  • The Haptoglobin genotype predicts cardio-renal mortality in type 1 diabetes.

    abstract:AIMS:The Haptoglobin (HP) 2-2 genotype increases cardiovascular diabetes complication incidence. In type 1 diabetes, HP 2-2 also predicts declining kidney function and end-stage renal disease. We investigated whether HP 2-2 predisposes to cardio-renal mortality, while considering other causes of death as competing risk...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2015.11.011

    authors: Costacou T,Orchard TJ

    更新日期:2016-03-01 00:00:00

  • Polymorphisms of myo-inositol oxygenase gene are associated with Type 1 diabetes mellitus.

    abstract::Myo-inositol oxygenase (MIOX) is the first and rate-limiting enzyme in myo-inositol (MI) metabolism pathway. The increase in MIOX enzyme activity is in proportion to serum glucose concentrations and may be responsible for the MI depletion found in the diabetic complications. The aim was to investigate whether single n...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2009.09.005

    authors: Yang B,Hodgkinson A,Millward BA,Demaine AG

    更新日期:2010-11-01 00:00:00

  • Toll-like receptors 2 and 4 mediate hyperglycemia induced macrovascular aortic endothelial cell inflammation and perturbation of the endothelial glycocalyx.

    abstract:OBJECTIVES:Hyperglycemia-induced inflammation is central to the vascular complications in diabetes. Toll-like receptors (TLRs) are key players in regulating inflammatory responses. There are sparse data on the role of TLR2 and TLR4 in regulating human macrovascular aortic endothelial cells (HMAECs) inflammation and gly...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2016.01.014

    authors: Pahwa R,Nallasamy P,Jialal I

    更新日期:2016-05-01 00:00:00

  • Oxidative stress pathway genes and chronic renal insufficiency in Asian Indians with Type 2 diabetes.

    abstract:BACKGROUND:There are significant regional variations in prevalence of diabetes and diabetic chronic renal insufficiency (CRI) in India. Oxidative stress plays an important role in the development of diabetic complications. To determine the importance of the polymorphisms in the genes involved in maintenance of cellular...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2007.10.003

    authors: Tiwari AK,Prasad P,B K T,Kumar KM,Ammini AC,Gupta A,Gupta R

    更新日期:2009-03-01 00:00:00

  • Renal pathological implications in type 2 diabetes mellitus patients with renal involvement.

    abstract:AIMS:To investigate the renal pathological implications in type 2 diabetes mellitus patients with renal involvement. METHODS:A total of 328 type 2 diabetes mellitus (T2DM) patients with renal involvement who underwent a renal biopsy and received follow-up for at least one year were recruited in our study. The patients...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2016.10.024

    authors: Li L,Zhang X,Li Z,Zhang R,Guo R,Yin Q,Yang L,Yue R,Su B,Huang S,Xu H,He C,Liu F

    更新日期:2017-01-01 00:00:00

  • Markers of endothelial dysfunction in hyperglycaemic Asian Indian subjects.

    abstract:OBJECTIVE:The aims of this study were the following: (1). to determine the levels of endothelin-1(ET1), soluble adhesion molecules like intracellular adhesion molecule-1 (sICAM-1), and vascular cell adhesion molecule-1 (sVCAM-1) in different stages of glucose intolerance and to identify a suitable marker of endothelial...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/S1056-8727(03)00037-0

    authors: Viswanathan V,Snehalatha C,Nair MB,Ramachandran A

    更新日期:2004-01-01 00:00:00

  • Vulvovaginitis and balanitis in patients with diabetes treated with dapagliflozin.

    abstract:BACKGROUND:Vulvovaginitis, balanitis, and related genital infections are common in patients with type 2 diabetes. Glucosuria, which is an outcome of treatment with sodium glucose cotransporter 2 (SGLT2) inhibitors, is among the possible causes. Dapagliflozin, an SGLT2 inhibitor with demonstrated glycemic benefits in pa...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.jdiacomp.2013.04.012

    authors: Johnsson KM,Ptaszynska A,Schmitz B,Sugg J,Parikh SJ,List JF

    更新日期:2013-09-01 00:00:00

  • Potential role of E4orf1 protein in aging-associated impairment in glycemic control.

    abstract::Aging constitutes a major risk factor for the development of type-2 diabetes (T2D) where glucose tolerance declines with age, resulting in a high prevalence of T2D and impaired glucose tolerance in the elderly population. Currently more than half of the 20 million U.S. adults with T2D are above the age of 60, and the ...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章,评审

    doi:10.1016/j.jdiacomp.2018.11.006

    authors: Gamage S,Reddy PH,Dhurandhar NV,Hegde V

    更新日期:2019-03-01 00:00:00

  • Soluble vascular cell adhesion molecule-1 and soluble E-selectin are associated with micro- and macrovascular complications in Type 1 diabetic patients.

    abstract:OBJECTIVE:There are no large studies in Type 1 diabetic patients that have examined the relation between soluble adhesion molecules and micro- and macrovascular outcomes, although the risks of such complications are high. Therefore, the main objective is to examine the relationship between soluble (s) vascular cell adh...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2005.06.005

    authors: Soedamah-Muthu SS,Chaturvedi N,Schalkwijk CG,Stehouwer CD,Ebeling P,Fuller JH,EURODIAB Prospective Complications Study group.

    更新日期:2006-05-01 00:00:00

  • Long-term treatment with metformin in type 2 diabetes and methylmalonic acid: Post hoc analysis of a randomized controlled 4.3year trial.

    abstract:AIMS:Metformin treatment is associated with a decrease of serum vitamin B12, but whether this reflects tissue B12 deficiency is controversial. We studied the effects of metformin on serum levels of methylmalonic acid (MMA), a biomarker for tissue B12 deficiency, and on onset or progression of neuropathy. METHODS:In th...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2017.11.001

    authors: Out M,Kooy A,Lehert P,Schalkwijk CA,Stehouwer CDA

    更新日期:2018-02-01 00:00:00

  • Is hyperfiltration associated with higher urine albumin-to-creatinine ratio at follow up among Indigenous Australians? The eGFR follow-up study.

    abstract:BACKGROUND:Glomerular hyperfiltration is not able to be detected in clinical practice. We assessed whether hyperfiltration is associated with albuminuria progression among Indigenous Australians at high risk of diabetes and kidney disease to determine its role in kidney disease progression. METHODS:Longitudinal observ...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2019.02.005

    authors: Ekinci EI,Barr ELM,Barzi F,Hughes JT,Lawton PD,Jones GRD,Hoy W,Cass A,Thomas M,Sinha A,Jerums G,O'Dea K,MacIsaac RJ,Maple-Brown LJ

    更新日期:2019-05-01 00:00:00

  • Effects of a synthetic retinoid on skin structure, matrix metalloproteinases, and procollagen in healthy and high-risk subjects with diabetes.

    abstract:BACKGROUND:In diabetes, foot ulceration may result from increased skin fragility. Retinoids can reverse some diabetes-induced deficits of skin structure and function, but their clinical utility is limited by skin irritation. The effects of diabetes and MDI 301, a nonirritating synthetic retinoid, and retinoic acid have...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2011.10.002

    authors: Zeng W,Tahrani A,Shakher J,Varani J,Hughes S,Dubb K,Stevens MJ

    更新日期:2011-11-01 00:00:00