Abstract：
:The effects on lipid and glucose metabolism of a hazelnut skin extract (FIBEROX™) administrated during 8 weeks (HFD-FBX8w group) or during the last 4 weeks of the study (HFD-FBX4w group) to Golden Syrian hamsters fed a high-fat diet (HFD) for 8 weeks were investigated. FIBEROX™ consumption reversed the increase in total and LDL plasma cholesterol induced by the HFD feeding in both HFD-FBX groups and decreased the circulating levels of free fatty acids and triglycerides in the HFD-FBX4w animals. The higher excretion of bile acids found in the faeces of both groups of hamsters fed the FIBEROX™ suggests that this mechanism is involved in the cholesterol-lowering effects of the extract. Furthermore, FIBEROX™ intake sharply decreased the lithocholic/deoxycholic bile acid faecal ratio, a risk factor for colon cancer, in both HFD-FBX groups. In conclusion, the consumption of FIBEROX™ improves different risk factors associated with cardiovascular disease and colon cancer.
journal_name
Food Chemjournal_title
Food chemistryauthors
Caimari A,Puiggròs F,Suárez M,Crescenti A,Laos S,Ruiz JA,Alonso V,Moragas J,Del Bas JM,Arola Ldoi
10.1016/j.foodchem.2014.06.072subject
Has Abstractpub_date
2015-01-15 00:00:00pages
138-44eissn
0308-8146issn
1873-7072pii
S0308-8146(14)00958-3journal_volume
167pub_type
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