Hemodynamic effect of norepinephrine and serotonin with and without indomethacin.

Abstract:

:Injections of serotonin (5-HT) into the aortic arch of rats caused greater reductions of blood pressure (BP) and less increases in renal vascular resistance (RVR) than that into jugular veins, in contrast to norepinephrine (NE) which tended to cause larger increases in BP and RVR by the intra-aortic route. Indomethacin (INDO) enhanced renal vasoconstrictor responses to NE, but did not affect those of 5-HT. These data support a central nervous system (CNS) hypotensive effect of 5-HT not shared by NE, and a less interaction with vasodilator prostaglandins for 5-HT, when compared with NE.

journal_name

Chin Med J (Engl)

journal_title

Chinese medical journal

authors

Ding XR,Stier C Jr,Harold I

subject

Has Abstract

pub_date

1989-06-01 00:00:00

pages

461-3

issue

6

eissn

0366-6999

issn

2542-5641

journal_volume

102

pub_type

杂志文章
  • Local tissue hypoxia and formation of nasal polyps.

    abstract:OBJECTIVE:To explore the response of nasal mucosa epithelial cells to hypoxia in terms of formation of nasal polyps (NP). METHODS:Epithelial cells of NP and inferior turbinate (IT) were cultured serum-free under normal oxygen and hypoxic circumstances with stimulation of IL-1 beta and TNF alpha. The vascular endotheli...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Jiang S,Dong Z,Zhu D,Yang Z

    更新日期:2003-02-01 00:00:00

  • Plasma neutrophil-gelatinase-associated lipocalin and cystatin C could early diagnose contrast-induced acute kidney injury in patients with renal insufficiency undergoing an elective percutaneous coronary intervention.

    abstract:BACKGROUND:Contrast induced acute kidney injury (CIAKI) is an important complication in the use of iodinated contrast media (CM). Our study was to evaluate the neutrophil gelatinase-associated lipocalin (NGAL) and cystatin C for early diagnosis of CIAKI. METHODS:The patients with established or suspected coronary arte...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Liu XL,Wang ZJ,Yang Q,Yu M,Shen H,Nie B,Han HY,Gao F,Zhou YJ

    更新日期:2012-03-01 00:00:00

  • Role of Whole-exome Sequencing in Phenotype Classification and Clinical Treatment of Pediatric Restrictive Cardiomyopathy.

    abstract:BACKGROUND:Restrictive cardiomyopathy (RCM) is the least common cardiomyopathy in which the walls are rigid and the heart is restricted from stretching and filling properly. Cardiac troponin I (cTnI) mutation-caused myofibril Ca2+ hypersensitivity has been shown to be associated with impaired diastolic function. This s...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.219150

    authors: Ding WH,Han L,Xiao YY,Mo Y,Yang J,Wang XF,Jin M

    更新日期:2017-12-05 00:00:00

  • Immunohistochemical study in dural arteriovenous fistula and possible role of ephrin-B2 for development of dural arteriovenous fistula.

    abstract:BACKGROUND:Although there were several clinical and experimental studies discussing the pathogenesis of dural arteriovenous fistula (DAVF), the pathological process leading to intracranial DAVF so far remains unknown. In this study, we investigated the expression of vascular growth factors in order to elucidate the pos...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Tirakotai W,Bian LG,Bertalanffy H,Siegfried B,Sure U

    更新日期:2004-12-01 00:00:00

  • Clinical significance of co-expression of VEGF-C and VEGFR-3 in non-small cell lung cancer.

    abstract:OBJECTIVE:To investigate the relationship between vascular endothelial growth factor C (VEGF-C) expression, VEGFR-3 expression, lymphangiogenesis and angiogenesis in human non-small cell lung cancer (NSCLC). METHODS:Seventy-six NSCLC samples were stained for VEGF-C, VEGFR-3 and CD34 with immunohistochemical methods. A...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Li Q,Dong X,Gu W,Qiu X,Wang E

    更新日期:2003-05-01 00:00:00

  • Anisodamine inhibits acetylcholine-induced endothelium-dependent relaxation of canine femoral artery.

    abstract::The effects of anisodamine on acetylcholine-induced endothelium-dependent relaxation were studied in organ chambers and under bioassay conditions. In organ chamber experiments, both acetylcholine and bradykinin induced an endothelium-dependent relaxation of norepinephrine-contracted canine femoral arteries in a concen...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Guo HY,Loren RR,Vanhutte PM

    更新日期:1992-08-01 00:00:00

  • Viral shedding in Chinese young adults with mild 2009 H1N1 influenza.

    abstract:BACKGROUND:The duration of viral shedding and the transmission of 2009 H1N1 influenza among individuals, especially among the younger population with mild illness, are not well understood now. The aim of this study was to determine the viral shedding of the young adult patients with mild 2009 H1N1 influenza in China. ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Jia N,Gao Y,Suo JJ,Xie LJ,Yan ZQ,Xing YB,He L,Liu YX

    更新日期:2011-05-01 00:00:00

  • The effect of platyspondyly and pubertal growth spurt on the stature of patients with beta-thalassaemia major.

    abstract:OBJECTIVE:To study the effect of the body proportion and pubertal growth spurt on the stature of children with beta-thalassaemia major. METHODS:The height, sitting height, upper to lower segment (U:L) ratio and pubertal development were determined in 71 Chinese children (38 girls and 33 boys) with beta-thalassaemia. T...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Low CK,Kwan YW,Cheung PT,Li MC,Ha SY,Lau YL,Karlberg J

    更新日期:1998-08-01 00:00:00

  • Human LINE1 endonuclease domain as a putative target of SARS-associated autoantibodies involved in the pathogenesis of severe acute respiratory syndrome.

    abstract:BACKGROUND:Severe acute respiratory syndrome (SARS) is a disease with a mortality of 9.56%. Although SARS is etiologically linked to a new coronavirus (SARS-CoV) and functional cell receptor has been identified, the pathogenesis of the virus infection is largely unclear. METHODS:The clinical specimens were processed a...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: He WP,Shu CL,Li BA,Zhao J,Cheng Y

    更新日期:2008-04-05 00:00:00

  • Pancreatic and duodenal homeobox-1 in pancreatic ductal adenocarcinoma and diabetes mellitus.

    abstract::Diabetes mellitus and pancreatic ductal adenocarcinoma are two common diseases worldwidely which are both derived from different components of pancreas. The pancreatic and duodenal homeobox-1 (PDX1) is an essential transcription factor for the early development of pancreas that is required for the differentiation of a...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,评审

    doi:10.1097/CM9.0000000000000628

    authors: Tang ZC,Chu Y,Tan YY,Li J,Gao S

    更新日期:2020-02-05 00:00:00

  • Impact of Baseline Bleeding Risk on Efficacy and Safety of Ticagrelor versus Clopidogrel in Chinese Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention.

    abstract:Background:There was still conflict on the antithrombotic advantage of ticagrelor versus clopidogrel among East Asian population with acute coronary syndrome (ACS). We considered that the baseline bleeding risk might be an undetected key factor that significantly affected the efficacy of ticagrelor. Methods:A total of...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.239306

    authors: Wang HY,Li Y,Xu XM,Li J,Han YL

    更新日期:2018-09-05 00:00:00

  • Safety and efficacy of a novel technique in the use of fractional flow reserve in complex coronary artery lesions.

    abstract:BACKGROUND:Fractional flow reserve (FFR) has become an increasingly important index when making decisions with respect to revascularization of coronary artery stenosis. However, the pressure guidewire used in obtaining FFR measurements is difficult to control and manipulate in certain complex coronary artery lesions, r...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.152664

    authors: He WM,Li CL,Sun Y,Zhou Z,Mai YF

    更新日期:2015-03-20 00:00:00

  • Effect of etomidate on voltage-dependent potassium currents in rat isolated hippocampal pyramidal neurons.

    abstract:BACKGROUND:Previous studies demonstrated general anesthetics affect potassium ion channels, which may be one of the mechanisms of general anesthesia. Because the effect of etomidate on potassium channels in rat hippocampus which is involved in memory function has not been studied, we investigated the effects of etomida...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Tan HY,Sun LN,Wang XL,Ye TH

    更新日期:2010-03-20 00:00:00

  • Unexpected positive cultures including isolation of Propionibacterium acnes in revision shoulder arthroplasty.

    abstract:OBJECTIVE:Little information is available to guide treatment strategies regarding patients with unexpected positive cultures (UPC), including Propionibacterium acnes (PA), without overt signs of infection in revision shoulder arthroplasty (RSA). The purpose of our study was to analyze the prevalence, clinical meaning, ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,评审

    doi:

    authors: Kim SJ,Kim JH

    更新日期:2014-01-01 00:00:00

  • Combined use of extended-release niacin and atorvastatin: safety and effects on lipid modification.

    abstract:BACKGROUND:Cholesterol-lowering therapy with statins has been reported to reduce the morbidity and mortality of cardiovascular diseases. This study aimed to investigate the effects of combined application of extended-release niacin and atorvastatin on lipid profile modification and the risks of adverse events in patien...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Sang ZC,Wang F,Zhou Q,Li YH,Li YG,Wang HP,Chen SY

    更新日期:2009-07-20 00:00:00

  • Serum isoforms of creatine kinase MM isoenzyme in acute myocardial infarction.

    abstract::Using the electrophoretic method, the changes in the catalytic activities of three CK-MM isoforms in multiple sequential serum samples of 12 patients with acute myocardial infarction (AMI) were monitored for 3 days after the onset of chest pain. In post-AMI period, MM3 reached a peak (518.6 U/L) first, on the average ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Yang XS,Meng QY

    更新日期:1993-06-01 00:00:00

  • Icariin associated with exercise therapy is an effective treatment for postmenopausal osteoporosis.

    abstract:BACKGROUND:There are no conclusive studies evaluating the interaction between icariin and exercise for treatment of osteoporosis; the efficacy and safety of this treatment combination remains to be evaluated. The purpose of this study was to investigate the effects of icariin treatment combined with exercise therapy on...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Liu M,Zhong C,He RX,Chen LF

    更新日期:2012-05-01 00:00:00

  • Aerosolized Amikacin as Adjunctive Therapy of Ventilator-associated Pneumonia Caused by Multidrug-resistant Gram-negative Bacteria: A Single-center Randomized Controlled Trial.

    abstract:BACKGROUND:Aerosolized amikacin (AA) is a current option for the management of ventilator-associated pneumonia (VAP) caused by multidrug-resistant Gram-negative bacteria (MDR-GNB), as it is reported that AA could increase the alveolar level of the drug without increasing systemic toxicity. This study aimed to evaluate ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,随机对照试验

    doi:10.4103/0366-6999.205846

    authors: Liu C,Zhang YT,Peng ZY,Zhou Q,Hu B,Zhou H,Li JG

    更新日期:2017-05-20 00:00:00

  • Diagnostic Value of Sensitive Biomarkers for Early Kidney Damage in Diabetic Patients with Normoalbuminuria.

    abstract:: ...

    journal_title:Chinese medical journal

    pub_type: 信件

    doi:10.4103/0366-6999.246080

    authors: Zhang D,Han QX,Wu MH,Shen WJ,Yang XL,Guo J,Pan SK,Liu ZS,Tang L,Cai GY,Chen XM,Zhu HY

    更新日期:2018-12-05 00:00:00

  • Procalcitonin could be a reliable marker in differential diagnosis of post-implantation syndrome and infection after percutaneous endovascular aortic repair.

    abstract:BACKGROUND:Thoracic endovascular aortic repair (TEVAR) is an emerging treatment modality, which has been rapidly embraced by clinicians treating thoracic aortic disease. However, the clinical manifestations of systemic inflammatory response after TEVAR as post-implantation syndrome (PIS) resemble the perioperative infe...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Xue L,Luo S,Luo J,Liu Z,Gu M,Kang H,Yang F,Nie B,Liu Y,Huang W,Xie N,He P,Dong H,Ni Z,Fan R,Chen J

    更新日期:2014-01-01 00:00:00

  • Crush stenting in treating coronary bifurcate lesions: paclitaxel eluting stents versus sirolimus eluting stents.

    abstract:BACKGROUND:Because no data regarding the comparison of crush stenting with paclitaxel (PES) or sirolimus eluting stents (SES) for coronary bifurcate lesions have been reported, we compared the clinical outcomes of these two types of stents. METHODS:Two hundred and thirty patients with 242 bifurcate lesions were enroll...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Chen SL,Zhang JJ,Ye F,Chen YD,Zhu ZS,Lin S,Tian NL,Liu ZZ,Fang WY,Sun XW,Hu DY,Kwan TW

    更新日期:2008-03-20 00:00:00

  • Stable clonal expansion of the T-cell receptor V beta 6, V beta 17 and V beta 19 T cells in a cGVHD case using genescan analysis.

    abstract:OBJECTIVE:To investigate the distribution and clonality of the T-cell receptor (TCR) V beta repertoire in chronic graft versus host disease (cGVHD). METHODS:The complementarity determining region 3 (CDR3) of the TCR beta gene with 24 variable regions was amplified in peripheral blood mononuclear cells drawn from one c...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Li Y,Du X,Xu M,Zhang T,Yang L,Chen S

    更新日期:2001-05-01 00:00:00

  • Mandibular functional reconstruction using internal distraction osteogenesis.

    abstract:OBJECTIVE:To study the potential and advantages of internal distraction osteogenesis in mandibular functional reconstruction. METHODS:Three types of mandibular distractors were used in eight patients with various mandibular defects due to tumor or cyst resection. The average age of the patients was 31.5 years old (age...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wang X,Lin Y,Yi B,Wang X,Liang C,Li Z

    更新日期:2002-12-01 00:00:00

  • Somatosensory evoked potentials in patients with cerebral hemorrhage and infarct. Correlation with CT, clinical data and their prognostic significance on limb function.

    abstract::Somatosensory evoked potentials (SEP) arising from median nerve stimulation were recorded in 102 patients with unilateral cerebral hemorrhage or infarct located in basal ganglion, internal capsule, thalamus or cerebral lobe. Of them 42 cases were followed up and reexamined with SEPs. Three types of SEPs were observed:...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Lu ZN,Yu SZ

    更新日期:1993-01-01 00:00:00

  • Effect of gynostemma pentaphyllum mak on carcinomatous conversions of golden hamster cheek pouches induced by dimethylbenzanthracene: a histological study.

    abstract:OBJECTIVE:To evaluate the effect of gynostemma pentaphyllum mak (GP) on carcinomatous conversions of leukoplasia of the golden hamster cheek pouch induced by dimethylbenzanthracene (DMBA). METHODS:284 golden hamsters, ranging from 4 to 8 weeks of age, 80 to 100 grams in weight were randomly divided into three groups: ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhou Z,Wang Y,Zhou Y,Zhang S

    更新日期:1998-09-01 00:00:00

  • Involvement of membrane glycophorins in human erythrocytes invaded by Plasmodium falciparum.

    abstract::The extent of participation and changes of glycophorins (GPs) and membrane proteins in the merozite-human erythrocyte interaction during the invasion of Plasmodium falciparum (Pf) were studied by immunoblotting techniques. Polyclonal antisera to alpha GP and to its C-terminal fragment (residues 82-131) as well as M an...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Liu JF,Lu YQ,Roth EF Jr,Nagel RL,Blumenfeld OO

    更新日期:1993-04-01 00:00:00

  • Early and long-term results of combined cardiac surgery and neoplastic resection in patients with concomitant severe heart disease and neoplasms.

    abstract:BACKGROUND:It is a surgical dilemma when patients present with both severe heart disease and neoplasms. The best surgical treatment remains controversial. This study aimed to analyze the early and long-term results of simultaneous surgical treatment of severe heart disease and neoplasms. METHODS:We reviewed the clinic...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Fu Q,Li QZ,Liang DG,Ruan XH,Wang ZX,Wei MX

    更新日期:2011-07-05 00:00:00

  • Microsurgical treatment of Nelson's syndrome.

    abstract:OBJECTIVE:To discuss the etiology, diagnostic criteria and treatment of Nelson's syndrome. METHODS:Twenty-three patients with Nelson's syndrome who were treated in our department over the last 19 years were analyzed retrospectively. Removal of adenoma by the transsphenoidal approach was done in 21 patients and by tran...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Xing B,Ren Z,Su C,Wang R,Yang Y,Hu Y

    更新日期:2002-08-01 00:00:00

  • Thin-section computed tomography detects long-term pulmonary sequelae 3 years after novel influenza A virus-associated pneumonia.

    abstract:BACKGROUND:The aim of this research was to evaluate long-term pulmonary sequelae on paired inspiration-expiration thin-section computed tomography (CT) scans 3 years after influenza A (H1N1) virus-associated pneumonia, and to analyze the affecting factors on pulmonary fibrosis. METHODS:Twenty-four patients hospitalize...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.154285

    authors: Xing ZH,Sun X,Xu L,Wu Q,Li L,Wu XJ,Shao XG,Zhao XQ,Wang JH,Ma LY,Wang K

    更新日期:2015-04-05 00:00:00

  • Performance and comparison of assessment models to predict 30-day mortality in patients with hospital-acquired pneumonia.

    abstract:BACKGROUND:Hospital-acquired pneumonia (HAP) is the most common hospital-acquired infection in China with substantial morbidity and mortality. But no specific risk assessment model has been well validated in patients with HAP. The aim of this study was to investigate the published risk assessment models that could pote...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.1097/CM9.0000000000001252

    authors: Wen JN,Li N,Guo CX,Shen N,He B

    更新日期:2020-12-03 00:00:00