Stable clonal expansion of the T-cell receptor V beta 6, V beta 17 and V beta 19 T cells in a cGVHD case using genescan analysis.

abstract：BACKGROUND:Tenofovir disoproxil (TDF) is a promising salvage therapy for patients with chronic hepatitis B (CHB) who failed regimens of other nucleoside analogues (NAs). In this study, we aimed to investigate the clinical efficacy and safety of TDF monotherapy in Chinese CHB patients with genotypic resistance. METHODS...

journal_title：Chinese medical journal

authors： Zhou J,Liu YY,Lian JS,Pan LF,Yang JL,Huang JR

更新日期：2017-04-20 00:00:00

abstract：BACKGROUND:Alpha 2A adrenergic receptor (AR) is a subtype of α2 AR belonging to G protein-coupled receptors, and exerts a variety of biological effects. Recent studies have demonstrated that the α2A AR activation was closely related with inflammatory reaction. The present study aimed to investigate the influence of α2A...

journal_title：Chinese medical journal

authors： Lin Y,Zhu X,Yao WZ,Yang YL,A LT,Chen L

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Acute lung injury (ALI) is a serious and common condition for which there are currently no specific strategies for treatment. Recent studies have suggested that bone marrow-derived multipotent mesenchymal stem cells (MSCs) may have therapeutic applications in multiple clinical disorders. We explored the biol...

journal_title：Chinese medical journal

authors： Liang ZX,Sun JP,Wang P,Tian Q,Yang Z,Chen LA

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Although breast-conserving surgery is one of the standard treatments for breast cancer, few studies have assessed its recent implementation in China. We aimed to clarify the current real-world status of breast-conserving surgery in China. METHODS:This cross-sectional survey relied on data collected by the C...

journal_title：Chinese medical journal

authors： Yu LX,Shi P,Tian XS,Yu ZG,Chinese Society of Breast Surgery.

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:This prospective, randomized, controlled study was designed to investigate the effects of a diabetes specific formula (Diason low energy: 313.8 kJ/100 ml), compared with a standard formula, on insulin sensitivity, serum C peptide, serum lipids and free fatty acid (FFA) in type 2 diabetics. METHODS:In total ...

journal_title：Chinese medical journal

authors： Li YX,Zeng JB,Yu K,Sun Q,Liu QY,Qin W,Zhang Q,Yu JC,Wang H

更新日期：2008-04-20 00:00:00

abstract：BACKGROUND:In many studies, obstructive sleep apnea (OSA) has been shown to be an independent risk factor for cardiovascular disease. Conversely, there are few reports establishing possible relation between OSA and venous thromboembolism (VTE). In this study, the aim is to evaluate OSA via polysomnography in patients w...

journal_title：Chinese medical journal

authors： Kezban OS,Ali NA,Umran T,Talha D,Ege GB,Peri A,Leyla YA,Hasan S

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Primary percutaneous coronary intervention (PCI) has been identified as the first therapeutic option for patients with acute ST-segment elevation myocardial infarction (STEMI). The strategy of transferring patient to a PCI center was recently recommended for those with acute STEMI who were present to PCI inc...

journal_title：Chinese medical journal

authors： Zhang Q,Zhang RY,Qiu JP,Zhang JF,Wang XL,Jiang L,Liao ML,Zhang JS,Hu J,Yang ZK,Shen WF

更新日期：2008-03-20 00:00:00

abstract：BACKGROUND:Previous studies suggested that zinc level was related to a certain diabetic microvascular complication. However, the relationship between zinc level and all the microvascular complications in type 2 diabetic patients remains unknown. The purpose of this study was to analyze the relationship between zinc lev...

journal_title：Chinese medical journal

authors： Luo YY,Zhao J,Han XY,Zhou XH,Wu J,Ji LN

更新日期：2015-12-20 00:00:00

abstract：BACKGROUND:Acute lung injury (ALI) and end-stage acute respiratory distress syndrome (ARDS) were among the most common causes of death in intensive care units. The activation of an inflammatory response and the damage of pulmonary epithelium and endotheliumwerethe hallmark of ALI/ARDS. Recent studies had demonstrated t...

journal_title：Chinese medical journal

authors： Xu YL,Liu YL,Wang Q,Li G,Lü XD,Kong B

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Receptor activator of nuclear factor kappa B (NF-κB) ligand (RANKL) and osteoprotegerin (OPG) have been recently shown to play important roles in bone resorption. The aim of this study was to investigate the possible association between the expression of bone resorption regulators (RANKL and OPG) and inflamm...

journal_title：Chinese medical journal

authors： Fan R,Sun B,Zhang CF,Lü YL,Xuan W,Wang QQ,Yin XZ

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Atypical meningioma is one of the rare subtypes of meningioma, which is lacking of optimal consensus on treatment strategies. This study aimed to investigate the radical treatment strategies to improve the long-term outcome of recurrent atypical meningiomas. METHODS:The prognostic factors including the age ...

journal_title：Chinese medical journal

authors： Li F,Lai ZP,Lin JK,Zhu G,Feng H

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:To investigate the expressions of hypothalamic arginine vasopressin (AVP) mRNA, renal AVP V2 receptor mRNA, and AVP-dependent aquaporin-2 (AQP2) mRNA in rats with adriamycin-induced nephrotic syndrome. Effects of Chinese herb Astragalus membranaceus (AM) were also tested. METHODS:Sprague-Dawley rats with fou...

journal_title：Chinese medical journal

authors： Ma J,Fan S,Chen J,Gu Y,Lin S

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between angiotensin-converting enzyme (ACE) gene insertion/deletion polymorphism and the clinico-pathological manifestations in patients with immunoglobulin nephropathy (IgAN). METHODS:A flanking primer pair and an insertion-specific primer pair were used to perform two polyme...

journal_title：Chinese medical journal

authors： Chen X,Liu S,Ye Y,Xu Q

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Neutrophil/lymphocyte ratio (NLR) has been proposed as a novel marker of systemic inflammation and oxidative stress. The objective of this study was to ascertain the relationship between levels of NLR and recurrence of lone atrial fibrillation (AF) after catheter ablation. METHODS:A total of 379 lone AF pat...

journal_title：Chinese medical journal

authors： Guo X,Zhang S,Yan X,Chen Y,Yu R,Long D,Sang C,Du X,Dong J,Ma C

更新日期：2014-01-01 00:00:00

abstract：:The recurrent rate of herpes simplex keratitis (HSK) was 4.17% after penetrating keratoplasty (PKP) was performed in 216 patients with HSK; the mean period of follow-up was 6.5 years. Immunohistochemical technique showed that HSV-1 antigens were present in the corneal stroma of rabbit eyes up to 45 days after primary ...

journal_title：Chinese medical journal

authors： Xie LX,Dong XG,Kaufman HE

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:The expression of TES, a novel tumor suppressor gene, is found to be down-regulated in the left anterior descending aorta of patients with coronary artery disease (CAD) compared with non-CAD subjects. This study aimed to investigate the expression of TES during the development of atherosclerosis in rabbits. ...

journal_title：Chinese medical journal

authors： Zhang Y,Yuan M,Li HM,Lao M,Xu Z,Li GP

更新日期：2015-06-20 00:00:00

abstract：OBJECTIVE:To summarize the recent findings on the epidemiology of medically important, opportunistic invasive fungal infections (IFIs) in China and discuss the relevant social, economical reasons and medical factors. DATA SOURCES:We performed a comprehensive search of both English and Chinese literatures of opportunis...

journal_title：Chinese medical journal

authors： Liao Y,Chen M,Hartmann T,Yang RY,Liao WQ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:C-arm-based flat-panel detector cone-beam computed tomography (CBCT) venography has never been used in the management of iliac vein compression syndrome (IVCS). This study aimed to determine the technical feasibility and safety of CBCT venography in the diagnosis of IVCS compared with conventional venography...

journal_title：Chinese medical journal

authors： Wang CM,Zhang WL,Li X

更新日期：2020-08-26 00:00:00

abstract：BACKGROUND:Muscle fibers overlying the intramyocardial segment of an epicardial coronary artery are termed myocardial bridging (MB). Variable prevalence of MB has been described at autopsy and angiographic series with small and large sample size studies. In addition, no similar study was reported in Chinese population....

journal_title：Chinese medical journal

authors： Li JJ,Shang ZL,Yao M,Li J,Yang YJ,Chen JL,Qiao SB,Ma WH,Qin XW,Liu HB,Wu YJ,Yuan JQ,Chen J,You SJ,Dai J,Xu B,Xia R,Gao RL

更新日期：2008-03-05 00:00:00

abstract：OBJECTIVE:To evaluate the use of oxygen in neonates in the past, present and future. DATA SOURCES:The data are mainly from Pubmed with relevant published articles from the 1940s to the present with some information gathered from web searches. STUDY SELECTION:Studies evaluating the use of oxygen in premature and term ...

journal_title：Chinese medical journal

authors： Dennery PA

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To evaluate mice as experimental animals for Chlamydia pneumoniae (C. pneumoniae) infection and investigate the pathogenesis of C. pneumoniae derived pneumonitis. METHODS:Icr mice were inoculated with the C. pneumoniae strain, CWL-029, either intranasally or intravenously. After a single dose inoculation, mi...

journal_title：Chinese medical journal

authors： Shi Y,Yin J,Zhan H,Feng G,Zhang X,Su X,Song Y,Xia X,Zhou X,Shen P

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Sinus of Valsalva aneurysm (SVA) is a rare anomaly and few large or long-term series are well established. This study was designed to review 33-year surgical experience of SVA in one center. METHODS:From August 1980 to December 2013, patients with SVA underwent surgical repair were retrospectively studied. ...

journal_title：Chinese medical journal

authors： Yan F,Abudureheman M,Huo Q,Shabiti A,Zhu T,Liu Z

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Pulsed radiofrequency (PRF) application to the dorsal root ganglia can reduce neuropathic pain (NP) in animal models, but the effect of PRF on damaged peripheral nerves has not been examined. We investigated the effect of PRF to the rat sciatic nerve (SN) on pain-related behavior and SN ultrastructure follow...

journal_title：Chinese medical journal

authors： Li DY,Meng L,Ji N,Luo F

更新日期：2015-02-20 00:00:00

abstract：BACKGROUND:Irritable bowel syndrome (IBS) is reported associated with the alteration of gut microbial composition termed as dysbiosis. However, the pathogenic mechanism of IBS remains unclear, while the studies of Chinese individuals are scarce. This study aimed to understand the concept of dysbiosis among patients wit...

journal_title：Chinese medical journal

authors： Wang Z,Xu CM,Liu YX,Wang XQ,Zhang L,Li M,Zhu SW,Xie ZJ,Wang PH,Duan LP,Zhu HQ

更新日期：2019-04-20 00:00:00

abstract：BACKGROUND:Coronary heart diseases (CHD) have been identified as one of topmost diseases affecting the Chinese population. However, depression in CHD has not been reported and there are limited high quality empirical studies in China focused on the prevalence of the comorbidity. This study aimed to estimate the pooled ...

journal_title：Chinese medical journal

authors： Ren Y,Yang H,Browning C,Thomas S,Liu M

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Chimerism analysis is an important tool for the surveillance of post-transplant engraftment. It offers the possibility of identifying impending graft rejection and recurrence of underlying malignant or non-malignant disease. Here we investigated the quantitative chimerism kinetics of 21 relapsed leukemia pat...

journal_title：Chinese medical journal

authors： Qin XY,Li GX,Qin YZ,Wang Y,Wang FR,Liu DH,Xu LP,Chen H,Han W,Wang JZ,Zhang XH,Li JL,Li LD,Liu KY,Huang XJ

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To explore the mechanism of cisplatin resistance and its reversion in human ovarian cancer. MATERIALS AND METHODS:A cisplatin resistant cell subline of SKOV3, SKOV3/cp, was established, and a xenograft mice model of human ovarian cancer was established by microencapsulation technology. Various biochemical ch...

journal_title：Chinese medical journal

authors： Liang Z,Bian D

更新日期：1996-05-01 00:00:00

abstract：:Temporary arterial occlusion during intracranial aneurysm surgery is a safe and effective modality. It is not only an emergency measure for controlling aneurysmal bleeding, but also a helpful means for accurate and meticulous dissection and clipping of an intracranial aneurysm with the advantage of minimizing the chan...

journal_title：Chinese medical journal

authors： Zhou LF,Li SQ,Yang ML

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:The importance of heart rate as secondary prevention strategies for patients with coronary artery disease (CAD) is emphasized by multiple guidelines. However, limited information is available on the heart rate distribution and the change patterns of resting heart rate when initiating beta-blocker therapy amo...

journal_title：Chinese medical journal

authors： Zhao YX,Li YP,Gao F,Ma HY,Wang ZJ,Han HY,Shen H,Zhou YJ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Although there are several drugs and drug combinations for the treatment of Pneumocystis carinii (P. carinii) pneumonia, all drugs have the toxicity as well as low efficacy. Iron chelators have been proposed as a source of new drugs for combating these infections. We hypothesized that iron chelators would su...

journal_title：Chinese medical journal

authors： Ye B,Zheng YQ,Wu WH,Zhang J

更新日期：2004-11-01 00:00:00