Abstract:
OBJECTIVES:We had for aim to determine the characteristics of carbapenemase-producing enterobacteria (CPE) carriers and to assess the economic impact of isolation measures leading to loss of activity (closed beds, prolonged hospital stays) and additional personnel hours. PATIENTS AND METHODS:We conducted a retrospective study for 2years (2012/2013), in a French general hospital, focusing on CPE carriers with clinical case description. The costs were estimated by comparing the activity of concerned units (excluding the ICU) during periods with CPE carriers or contacts, during the same periods of the year (n-1), plus additional hours and rectal swabs. RESULTS:Sixteen EPC carriers were identified: 10 men and 6 women, 65±10years of age. Seven patients acquired EPC in hospital during 2 outbreaks in 2012. Four patients presented with an infection (peritonitis, catheter infection, and 2 cases of obstructive pyelonephritis) with a favorable outcome. The median length of stay was 21days [4,150]. Six patients died, 1 death was indirectly due to CPE because of inappropriate empiric antibiotic therapy. A decrease in activity was observed compared to the previous year with an estimated 547,303€ loss. The 1779 additional hours cost 63,870€, and 716 screening samples cost 30,931€. The total additional cost was estimated at 642,104€ for the institution. CONCLUSIONS:Specialized teams for CPE carriers and isolation of contact patients, required to avoid/control epidemics, have an important additional cost. An appreciation of their support is needed, as well as participation of rehabilitation units.
journal_name
Med Mal Infectjournal_title
Medecine et maladies infectieusesauthors
Daroukh A,Delaunay C,Bigot S,Ceci JM,Siddhoun N,Bukreyeva I,Raisin J,Porcheret H,Maisonneuve L,Bouldouyre MAdoi
10.1016/j.medmal.2014.06.004subject
Has Abstractpub_date
2014-07-01 00:00:00pages
321-6issue
7eissn
0399-077Xissn
1769-6690pii
S0399-077X(14)00155-3journal_volume
44pub_type
杂志文章abstract:OBJECTIVES:Errors are frequently made in the prescription of antiretroviral medication for hospitalized HIV-infected patients. We had for aim to evaluate the prescription of antiretroviral drug regimens at hospital admission and the impact of a strategy implemented to prevent errors. METHODS:HIV-infected patients mana...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2013.07.006
更新日期:2013-09-01 00:00:00
abstract:INTRODUCTION:The aim of our study was to determine the epidemiological profile and the antibiotics susceptibility of bacteria identified in blood culture in the intensive care unit, to improve empirical antibiotherapy. MATERIAL AND METHOD:A retrospective study was made over a four-year period (2002-2005) in the intens...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2007.10.006
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Monkeypox is a zoonosis caused by an Orthopoxvirus of the Poxviridae family. Human infections are often severe and are a public health problem. PATIENTS AND METHOD:We conducted a monkeypox outbreak investigation of suspected case patients in five villages of the Alindao-Mingala Health District following blo...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2018.02.010
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVE:To assess the proportion of patients meeting the 2010 SPILF-AFSSAPS guiding criteria for Streptococcuspneumoniae in patients consulting at the emergency departments of four French university hospitals for acute community-acquired pneumonia (CAP) suspicion. PATIENTS AND METHODS:The PACSCAN study prospectively...
journal_title:Medecine et maladies infectieuses
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doi:10.1016/j.medmal.2020.09.004
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abstract:BACKGROUND:The extended-release formulation of clarithromycin (CLA-ER) allows using this macrolide as a single daily dose. The purpose of this study was to evaluate the efficacy and safety of the CLA-ER formulation (500 mgx2) vs telithromycin (TELI) (400 mgx2) as a short course 5-day treatment, once a day, in patients ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.medmal.2005.07.002
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:This study had for aim to describe the clinical aspects and favoring factors of mucosal Leishmaniasis in an Amazonian population of 30,000 habitants in Guajara-Mirim (Rondonia-Brazil). MATERIAL AND METHOD:A descriptive study was made of 16 patients with mucosal Leishmaniasis among 170 patients infected by L...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2007.03.012
更新日期:2007-06-01 00:00:00
abstract:INTRODUCTION:An increase of syphilis cases has been recorded in the past few decades, especially among HIV-infected patients. These patients often present with concomitant primary and secondary lesions or extensive presentations of syphilis. OBJECTIVE:Our goal was to compare alternative regimens to the recommended pen...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2011.10.003
更新日期:2012-01-01 00:00:00
abstract::This review concerning the major lower respiratory tract pathogens in France has for aim to describe the epidemiology of resistance to beta-lactams, macrolides, ketolides, and fluoroquinolones especially in Streptococcus pneumoniae and Haemophilus influenzae. It should also provide new insights on the mechanisms of ac...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2006.05.015
更新日期:2006-11-01 00:00:00
abstract:INTRODUCTION:Persistent high-risk HPV (HR-HPV) infection is associated with a greater risk of cervical cancer. PATIENTS AND METHODS:Statistical data on the prevalence of HR-HPV infections in the Algerian population is lacking. We conducted a prospective study of 300 women aged between 25 and 50 years, screened for cer...
journal_title:Medecine et maladies infectieuses
pub_type: 临床试验,杂志文章
doi:10.1016/j.medmal.2017.05.013
更新日期:2017-11-01 00:00:00
abstract::Treatment indications for tuberculosis-infection depend on each case, but also on public health policy in each country. This policy usually made at the national level depends on tuberculosis epidemiology of the population concerned and on the country's socio-economic level of development, and more especially of its he...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:
更新日期:2004-08-01 00:00:00
abstract::We report a fatal case of Chromobacterium violaceum septicemia in a 42-year-old farm worker living in the French West Indies. The bacteria found in the muddy soil and the stagnant water of tropical and subtropical regions is rarely a source of human infection. ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2006.08.004
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:This study had for aim to assess pneumococcal vaccination rates in hospitalized patients. DESIGN:A prospective study was carried out in two medical wards of the Nice University Hospital, France. Patients were included from December 31, 2007 to February 12, 2008. RESULTS:Hundred and thirty-seven patients, ag...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2009.12.004
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVES:The main objective of this study was to compare the efficacy of three regimens of malaria prevention during pregnancy for the reduction of anemia between the first and third antenatal consultations. The first treatment arm was the classical weekly chemoprophylaxis with chloroquine; the other two were the int...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.medmal.2007.10.012
更新日期:2008-04-01 00:00:00
abstract:INTRODUCTION:No therapy has yet proven effective in COVID-19. Tocilizumab (TCZ) in patients with severe COVID-19 could be an effective treatment. METHOD:We conducted a retrospective case-control study in the Nord Franche-Comté Hospital, France. We compared the outcome of patients treated with TCZ and patients without ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2020.05.001
更新日期:2020-08-01 00:00:00
abstract::For the next decade, COPD will become the third cause of mortality in the world. COPD is mainly due to cigarette smoking and presents different levels of severity according to people, probably linked to environmental and genetic factors, which are not well documented. Recent publications pointed out bacterial bronchia...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2005.12.006
更新日期:2006-05-01 00:00:00
abstract::Any person travelling in countries where yellow fever (YF) is endemic and without presenting contra-indication for the vaccination against YF may be vaccinated. This vaccination can very rarely induce a potentially lethal neurotropic or viscerotropic disease. In severely immunodeficient patients, the vaccination is co...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2008.06.031
更新日期:2008-10-01 00:00:00
abstract:INTRODUCTION:Acinetobacter baumannii is a ubiquitous pathogen resistant to desiccation and responsible for healthcare-associated infections (HAI), especially in intensive care units (ICU) where it is responsible for 5-10% of HAIs. An A. baumannii outbreak occurred in the ICU of the University Hospital of Angers, France...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2017.06.003
更新日期:2017-10-01 00:00:00
abstract::Cet article a du être retiré conformément à la ligne de conduite d'Elsevier concernant le retrait d'articles. Vous pouvez consulter le site (http://www.elsevier.com/locate/withdrawalpolicy) pour de plus amples renseignements. L'éditeur vous prie d'accepter ses excuses pour ce désagrément. ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2008.11.009
更新日期:2008-12-27 00:00:00
abstract:UNLABELLED:Self-medication with antibiotics is all the more disturbing in developing countries where this type of medication is easily available, and often without any prescription. OBJECTIVES:The authors wanted to assess and describe self-medication with antibiotics and identify the factors and public perception asso...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2009.10.002
更新日期:2010-06-01 00:00:00
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journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2016.06.004
更新日期:2016-10-01 00:00:00
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journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2016.02.002
更新日期:2016-05-01 00:00:00
abstract::Less than 20% of African adolescents aged 10-19 years are aware of their HIV status, whereas HIV screening remains the gateway to care and while AIDS has become the leading cause of death among adolescents in Sub-Saharan Africa. According to the UNAIDS target, scalable HIV testing strategies specific to various age gr...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2020.07.007
更新日期:2020-11-01 00:00:00
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journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,多中心研究
doi:10.1016/j.medmal.2010.06.007
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:This retrospective study was undertaken to assess epidemiological and clinical aspects as well as outcome of tetanus cases in patients over 28 days of age, so as to issue recommendations. PATIENTS AND METHODS:This study included patients admitted to the Fann teaching hospital in Dakar from 2001 to 2003. Age,...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2004.11.003
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate the adequacy and the conformity of prescriptions of new systemic antifungal drugs to guidelines and scientific data. PATIENTS AND METHODS:Each prescription of liposomal amphotericin B (lip Amb), voriconazole, and caspofungin made between May 2003 and May 2004 in a teach...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2007.05.009
更新日期:2007-12-01 00:00:00
abstract:UNLABELLED:Rabies is responsible for 50,000 deaths per year worldwide. Mainland France has been officially freed from rabies in non-flying animals since 2001. METHOD:We wanted to provide an update on the French situation, using published data, and describe possible options since official guidelines are lacking. RESUL...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,评审
doi:10.1016/j.medmal.2014.05.002
更新日期:2014-07-01 00:00:00
abstract:INTRODUCTION:Varicella occurring in healthy adults may extend to the lungs. Diagnosing this complication is sometimes difficult because of the discrepancy between imaging and clinical presentation usually reported in this affection. METHOD:The authors report the result of a retrospective study on 106 immunocompetent p...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2008.09.025
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:Our objective was to estimate the case fatality rates of Zaire, Sudan, and Bundibugyo Ebola species, responsible for sometimes-lethal hemorrhagic fevers. METHODS:We performed a meta-analysis of World Health Organization data on outbreaks of infections due to theses species. RESULTS:Twenty outbreaks, includi...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章,meta分析
doi:10.1016/j.medmal.2014.08.005
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:To study the efficacy and safety of micafungin for prophylaxis of invasive fungal infections in patients undergoing induction chemotherapy for acute myeloid leukemia. PATIENTS AND METHODS:A prospective observational single-center study of 41 patients from the hematology department between May 2012 and April ...
journal_title:Medecine et maladies infectieuses
pub_type: 杂志文章
doi:10.1016/j.medmal.2016.03.008
更新日期:2016-06-01 00:00:00
abstract::Lyme borreliosis is transmitted en France by the tick Ixodes ricinus, endemic in metropolitan France. In the absence of vaccine licensed for use in humans, primary prevention mostly relies on mechanical protection (clothes covering most parts of the body) that may be completed by chemical protection (repulsives). Seco...
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pub_type: 杂志文章,实务指引,评审
doi:10.1016/j.medmal.2019.04.381
更新日期:2019-08-01 00:00:00