A mortise-tenon joint in the transmembrane domain modulates autotransporter assembly into bacterial outer membranes.

abstract：:Transmission-blocking interventions aim to reduce the prevalence of infection in endemic communities by targeting Plasmodium within the insect host. Although many studies have reported the successful reduction of infection in the mosquito vector, direct evidence that there is an onward reduction in infection in the ve...

journal_title：Nature communications

authors： Blagborough AM,Churcher TS,Upton LM,Ghani AC,Gething PW,Sinden RE

更新日期：2013-01-01 00:00:00

abstract：:Physical properties of multi-orbital materials depend not only on the strength of the effective interactions among the valence electrons but also on their type. Strong correlations are caused by either Mott physics that captures the Coulomb repulsion among charges, or Hund physics that aligns the spins in different or...

journal_title：Nature communications

authors： Deng X,Stadler KM,Haule K,Weichselbaum A,von Delft J,Kotliar G

更新日期：2019-06-20 00:00:00

abstract：:Processing of interleukin RNAs must be tightly controlled during the immune response. Here we report that a subnuclear body called the interleukin-6 and -10 splicing activating compartment (InSAC) is a nuclear site of cytokine RNA production and stability. Tat-activating regulatory DNA-binding protein-43 (TDP-43) acts...

journal_title：Nature communications

authors： Lee S,Lee TA,Lee E,Kang S,Park A,Kim SW,Park HJ,Yoon JH,Ha SJ,Park T,Lee JS,Cheon JH,Park B

更新日期：2015-01-05 00:00:00

abstract：:Chromosomal rearrangements are essential events in the pathogenesis of both malignant and nonmalignant disorders, yet the factors affecting their formation are incompletely understood. Here we develop a zinc-finger nuclease translocation reporter and screen for factors that modulate rearrangements in human cells. We i...

journal_title：Nature communications

authors： Day TA,Layer JV,Cleary JP,Guha S,Stevenson KE,Tivey T,Kim S,Schinzel AC,Izzo F,Doench J,Root DE,Hahn WC,Price BD,Weinstock DM

更新日期：2017-04-27 00:00:00

abstract：:Metal-organic frameworks (MOFs) are well known for their tunable structure and porosity. Many studies have shown they are promising for various important applications, for which their performance can be further enhanced by encapsulating functional species, such as luminescent guest molecules, within the frameworks. Al...

journal_title：Nature communications

authors： Sun CY,Wang XL,Zhang X,Qin C,Li P,Su ZM,Zhu DX,Shan GG,Shao KZ,Wu H,Li J

更新日期：2013-01-01 00:00:00

abstract：:Self-assembly of small molecules in water to form nanofibres, besides generating sophisticated biomaterials, promises a simple system inside cells for regulating cellular processes. But lack of a convenient approach for studying the self-assembly of small molecules inside cells hinders the development of such systems....

journal_title：Nature communications

authors： Gao Y,Shi J,Yuan D,Xu B

更新日期：2012-01-01 00:00:00

abstract：:RNAs contain post-transcriptional modifications, which fulfill a variety of functions in translation, secondary structure stabilization and cellular stress survival. Here, 2-methylthiocytidine (ms2C) is identified in tRNA of E. coli and P. aeruginosa using NAIL-MS (nucleic acid isotope labeling coupled mass spectromet...

journal_title：Nature communications

authors： Reichle VF,Petrov DP,Weber V,Jung K,Kellner S

更新日期：2019-12-06 00:00:00

abstract：:The separation of immiscible liquids has significant implications for magma evolution and the formation of magmatic ore deposits. We combine high-resolution imaging and electron probe microanalysis with the first use of atom probe tomography on tholeiitic basaltic glass from Hawaii, the Snake River Plain, and Iceland,...

journal_title：Nature communications

authors： Honour VC,Holness MB,Charlier B,Piazolo SC,Namur O,Prosa TJ,Martin I,Helz RT,Maclennan J,Jean MM

更新日期：2019-10-23 00:00:00

abstract：:Optical tracking is often combined with conventional flat panel solar cells to maximize electrical power generation over the course of a day. However, conventional trackers are complex and often require costly and cumbersome structural components to support system weight. Here we use kirigami (the art of paper cutting...

journal_title：Nature communications

authors： Lamoureux A,Lee K,Shlian M,Forrest SR,Shtein M

更新日期：2015-09-08 00:00:00

abstract：:Rotational invariance strongly constrains the viscosity tensor of classical fluids. When this symmetry is broken in anisotropic materials a wide array of novel phenomena become possible. We explore electron fluid behaviors arising from the most general viscosity tensors in two and three dimensions, constrained only th...

journal_title：Nature communications

authors： Varnavides G,Jermyn AS,Anikeeva P,Felser C,Narang P

更新日期：2020-09-18 00:00:00

abstract：:The Lyme disease agent, Borrelia burgdorferi, colonizes the gut of the tick Ixodes scapularis, which transmits the pathogen to vertebrate hosts including humans. Here we show that B. burgdorferi colonization increases the expression of several tick gut genes including pixr, encoding a secreted gut protein with a Reele...

journal_title：Nature communications

authors： Narasimhan S,Schuijt TJ,Abraham NM,Rajeevan N,Coumou J,Graham M,Robson A,Wu MJ,Daffre S,Hovius JW,Fikrig E

更新日期：2017-08-04 00:00:00

abstract：:One of the main reasons why nonlinear-optical signal processing (regeneration, logic, etc.) has not yet become a practical alternative to electronic processing is that the all-optical elements with nonlinear input-output relationship have remained inherently single-channel devices (just like their electronic counterpa...

journal_title：Nature communications

authors： Li L,Patki PG,Kwon YB,Stelmakh V,Campbell BD,Annamalai M,Lakoba TI,Vasilyev M

更新日期：2017-10-12 00:00:00

abstract：:In the original version of this Article, the legend in the upper panel of Figure 2 incorrectly read 'paternal imprinting' and should have read 'maternal imprinting'. This has been corrected in both the PDF and HTML versions of the Article. ...

journal_title：Nature communications

authors： Zeng Y,Amador C,Xia C,Marioni R,Sproul D,Walker RM,Morris SW,Bretherick A,Canela-Xandri O,Boutin TS,Clark DW,Campbell A,Rawlik K,Hayward C,Nagy R,Tenesa A,Porteous DJ,Wilson JF,Deary IJ,Evans KL,McIntosh AM,Nava

更新日期：2019-05-01 00:00:00

abstract：:For many stochastic processes, the probability [Formula: see text] of not-having reached a target in unbounded space up to time [Formula: see text] follows a slow algebraic decay at long times, [Formula: see text]. This is typically the case of symmetric compact (i.e. recurrent) random walks. While the persistence exp...

journal_title：Nature communications

authors： Levernier N,Dolgushev M,Bénichou O,Voituriez R,Guérin T

更新日期：2019-07-05 00:00:00

abstract：:The Aharonov-Bohm effect is one of the most intriguing phenomena in both classical and quantum physics, and associates with a number of important and fundamental issues in quantum mechanics. The Aharonov-Bohm effects of charged particles have been experimentally demonstrated and found applications in various fields. R...

journal_title：Nature communications

authors： Li E,Eggleton BJ,Fang K,Fan S

更新日期：2014-01-01 00:00:00

abstract：:The advent of super-resolution imaging (SRI) has created a need for optimized labelling strategies. We present a new method relying on fluorophore-conjugated monomeric streptavidin (mSA) to label membrane proteins carrying a short, enzymatically biotinylated tag, compatible with SRI techniques including uPAINT, STED a...

journal_title：Nature communications

authors： Chamma I,Letellier M,Butler C,Tessier B,Lim KH,Gauthereau I,Choquet D,Sibarita JB,Park S,Sainlos M,Thoumine O

更新日期：2016-03-16 00:00:00

abstract：:Solar-driven photocatalysis has attracted significant attention in water splitting, CO2 reduction and organic synthesis. The syntheses of valuable azo- and azoxyaromatic dyes via selective photoreduction of nitroaromatic compounds have been realised using supported plasmonic metal nanoparticles at elevated temperature...

journal_title：Nature communications

authors： Dai Y,Li C,Shen Y,Lim T,Xu J,Li Y,Niemantsverdriet H,Besenbacher F,Lock N,Su R

更新日期：2018-01-04 00:00:00

abstract：:Bacteria release membrane vesicles (MVs) that play important roles in various biological processes. However, the mechanisms of MV formation in Gram-positive bacteria are unclear, as these cells possess a single cytoplasmic membrane that is surrounded by a thick cell wall. Here we use live cell imaging and electron cry...

journal_title：Nature communications

authors： Toyofuku M,Cárcamo-Oyarce G,Yamamoto T,Eisenstein F,Hsiao CC,Kurosawa M,Gademann K,Pilhofer M,Nomura N,Eberl L

更新日期：2017-09-07 00:00:00

abstract：:An evolutionary account of human language as a neurobiological system must distinguish between human-unique neurocognitive processes supporting language and evolutionarily conserved, domain-general processes that can be traced back to our primate ancestors. Neuroimaging studies across species may determine whether can...

journal_title：Nature communications

authors： Wilson B,Kikuchi Y,Sun L,Hunter D,Dick F,Smith K,Thiele A,Griffiths TD,Marslen-Wilson WD,Petkov CI

更新日期：2015-11-17 00:00:00

abstract：:Human pre-implantation embryonic development involves extensive changes in chromatin structure and transcriptional activity. Here, we report on LiCAT-seq, a technique that enables simultaneous profiling of chromatin accessibility and gene expression with ultra-low input of cells, and map the chromatin accessibility an...

journal_title：Nature communications

authors： Liu L,Leng L,Liu C,Lu C,Yuan Y,Wu L,Gong F,Zhang S,Wei X,Wang M,Zhao L,Hu L,Wang J,Yang H,Zhu S,Chen F,Lu G,Shang Z,Lin G

更新日期：2019-01-21 00:00:00

abstract：:The COVID-19 epidemic hit Italy particularly hard, yielding the implementation of strict national lockdown rules. Previous modelling studies at the national level overlooked the fact that Italy is divided into administrative regions which can independently oversee their own share of the Italian National Health Service...

journal_title：Nature communications

authors： Della Rossa F,Salzano D,Di Meglio A,De Lellis F,Coraggio M,Calabrese C,Guarino A,Cardona-Rivera R,De Lellis P,Liuzza D,Lo Iudice F,Russo G,di Bernardo M

更新日期：2020-10-09 00:00:00

abstract：:Fatty acids (FAs) are essential nutrients, but how they are transported into cells remains unclear. Here, we show that FAs trigger caveolae-dependent CD36 internalization, which in turn delivers FAs into adipocytes. During the process, binding of FAs to CD36 activates its downstream kinase LYN, which phosphorylates DH...

journal_title：Nature communications

authors： Hao JW,Wang J,Guo H,Zhao YY,Sun HH,Li YF,Lai XY,Zhao N,Wang X,Xie C,Hong L,Huang X,Wang HR,Li CB,Liang B,Chen S,Zhao TJ

更新日期：2020-09-21 00:00:00

abstract：:The diversity in our genome is crucial to understanding the demographic history of worldwide populations. However, we have yet to know whether subtle genetic differences within a population can be disentangled, or whether they have an impact on complex traits. Here we apply dimensionality reduction methods (PCA, t-SNE...

journal_title：Nature communications

authors： Sakaue S,Hirata J,Kanai M,Suzuki K,Akiyama M,Lai Too C,Arayssi T,Hammoudeh M,Al Emadi S,Masri BK,Halabi H,Badsha H,Uthman IW,Saxena R,Padyukov L,Hirata M,Matsuda K,Murakami Y,Kamatani Y,Okada Y

更新日期：2020-03-26 00:00:00

abstract：:Adult stem cells commonly give rise to transit-amplifying progenitors, whose progeny differentiate into distinct cell types. It is unclear if stem cell niche signals coordinate fate decisions within the progenitor pool. Here we use quantitative analysis of Wnt, Hh, and Notch signalling reporters and the cell fate mark...

journal_title：Nature communications

authors： Dai W,Peterson A,Kenney T,Burrous H,Montell DJ

更新日期：2017-11-01 00:00:00

abstract：:Two-dimensional atomic crystals, such as two-dimensional oxides, have attracted much attention in energy storage because nearly all of the atoms can be exposed to the electrolyte and involved in redox reactions. However, current strategies are largely limited to intrinsically layered compounds. Here we report a genera...

journal_title：Nature communications

authors： Xiao X,Song H,Lin S,Zhou Y,Zhan X,Hu Z,Zhang Q,Sun J,Yang B,Li T,Jiao L,Zhou J,Tang J,Gogotsi Y

更新日期：2016-04-22 00:00:00

abstract：:Irreversible phase transformation of layered structure into spinel structure is considered detrimental for most of the layered structure cathode materials. Here we report that this presumably irreversible phase transformation can be rendered to be reversible in sodium birnessite (NaxMnO2·yH2O) as a basic structural un...

journal_title：Nature communications

authors： Jo MR,Kim Y,Yang J,Jeong M,Song K,Kim YI,Lim JM,Cho M,Shim JH,Kim YM,Yoon WS,Kang YM

更新日期：2019-09-02 00:00:00

abstract：:Acetylene hydrochlorination is an important coal-based technology for the industrial production of vinyl chloride, however it is plagued by the toxicity of the mercury chloride catalyst. Therefore extensive efforts have been made to explore alternative catalysts with various metals. Here we report that a nanocomposite...

journal_title：Nature communications

authors： Li X,Pan X,Yu L,Ren P,Wu X,Sun L,Jiao F,Bao X

更新日期：2014-04-22 00:00:00

abstract：:Wnt signaling is critical for directing epithelial gland development within the uterine lining to ensure successful gestation in adults. Wnt-dependent, Lgr5-expressing stem/progenitor cells are essential for the development of glandular epithelia in the intestine and stomach, but their existence in the developing repr...

journal_title：Nature communications

authors： Seishima R,Leung C,Yada S,Murad KBA,Tan LT,Hajamohideen A,Tan SH,Itoh H,Murakami K,Ishida Y,Nakamizo S,Yoshikawa Y,Wong E,Barker N

更新日期：2019-11-26 00:00:00

abstract：:Pulmonary carcinoids are rare neuroendocrine tumours of the lung. The molecular alterations underlying the pathogenesis of these tumours have not been systematically studied so far. Here we perform gene copy number analysis (n=54), genome/exome (n=44) and transcriptome (n=69) sequencing of pulmonary carcinoids and obs...

journal_title：Nature communications

authors： Fernandez-Cuesta L,Peifer M,Lu X,Sun R,Ozretić L,Seidal D,Zander T,Leenders F,George J,Müller C,Dahmen I,Pinther B,Bosco G,Konrad K,Altmüller J,Nürnberg P,Achter V,Lang U,Schneider PM,Bogus M,Soltermann A,Brustu

更新日期：2014-03-27 00:00:00

abstract：:Non-symmorphic chiral topological crystals host exotic multifold fermions, and their associated Fermi arcs helically wrap around and expand throughout the Brillouin zone between the high-symmetry center and surface-corner momenta. However, Fermi-arc splitting and realization of the theoretically proposed maximal Chern...

journal_title：Nature communications

authors： Yao M,Manna K,Yang Q,Fedorov A,Voroshnin V,Valentin Schwarze B,Hornung J,Chattopadhyay S,Sun Z,Guin SN,Wosnitza J,Borrmann H,Shekhar C,Kumar N,Fink J,Sun Y,Felser C

更新日期：2020-04-27 00:00:00