LKB1 loss at transcriptional level promotes tumor malignancy and poor patient outcomes in colorectal cancer.

abstract：BACKGROUND:The purpose of this study was to determine whether routine biologic tumor markers can predict lymph node status. The authors attempted to discover whether predictors of axillary lymph node metastasis based on biologic characteristic of primary breast cancers exist. METHODS:Eight hundred and fifty-one patien...

journal_title：Annals of surgical oncology

authors： Velanovich V,Szymanski W

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Carefully selected patients with noncolorectal, nonneuroendocrine (NCNN) liver metastases may benefit from hepatic resection. The incidence of occult unresectable disease and the possible benefits of staging laparoscopy in these patients are not known. METHODS:From December 1997 to July 2000, staging laparo...

journal_title：Annals of surgical oncology

authors： D'Angelica M,Jarnagin W,Dematteo R,Conlon K,Blumgart LH,Fong Y

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Granulomatous mastitis is an uncommon chronic inflammatory breast condition that is characterized by granulomatous inflammation. Granulomatous mastitis presents a challenging clinical scenario, because it can mimic carcinoma. The etiology and optimal treatment remain unclear. We report our experience with gr...

journal_title：Annals of surgical oncology

authors： Joseph KA,Luu X,Mor A

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:The usefulness of enteral nutrition via a nasointestinal tube for patients who develop postoperative pancreatic fistula (POPF) after miscellaneous pancreatectomy procedures has been reported. However, no clear evidence regarding whether oral intake is possible during management of POPF after pancreatoduodene...

journal_title：Annals of surgical oncology

authors： Fujii T,Nakao A,Murotani K,Okamura Y,Ishigure K,Hatsuno T,Sakai M,Yamada S,Kanda M,Sugimoto H,Nomoto S,Takeda S,Morita S,Kodera Y

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:In 2003, the American Joint Committee on Cancer (AJCC) initiated the 6th edition staging criteria, including pN0(i+) and pN1mi categories for breast cancer. However, the clinical significance of these categories is debated in the literature. METHODS:A prospective registry was used to identify patients stage...

journal_title：Annals of surgical oncology

authors： Pugliese MS,Beatty JD,Tickman RJ,Allison KH,Atwood MK,Szymonifka J,Arthurs ZM,Huynh PP,Dawson JH

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Although pancreatic cancer is the fourth leading cause of cancer death, few studies have evaluated population-based trends in diagnosis, management, and outcome. METHODS:We used the Surveillance, Epidemiology, and End Results (SEER) registry to evaluate treatment trends and outcomes for patients 18 or older...

journal_title：Annals of surgical oncology

authors： Baxter NN,Whitson BA,Tuttle TM

更新日期：2007-04-01 00:00:00

abstract：:Many examples highlight the power of gene expression profiles, or signatures, to provide an understanding of biological phenotypes. This is best seen in the context of cancer, where expression signatures have tremendous power to identify new cancer subtypes and to predict clinical outcomes. Gene expression profiles ha...

journal_title：Annals of surgical oncology

authors： Stevenson M,Potti A

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:The aim of this study was to report the incidence of lung cancer in patients with hematological malignancy (HM), as well as patient characteristics and outcome. METHODS:We investigated 1503 consecutive patients treated for HM and 1208 patients who underwent surgical resection for lung cancer. RESULTS:Lung can...

journal_title：Annals of surgical oncology

authors： Shoji F,Yamazaki K,Kouso H,Mori R,Takase K,Okamura S,Takeo S

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Magnetic resonance cholangiopancreatography (MRCP) is a new noninvasive diagnostic method for pancreaticobiliary (PB) imaging without endoscopy, sedation, or iodinated contrast. The purpose of this study was to evaluate the ability of MRCP to depict pancreatic and biliary ductal anatomy compared to that of e...

journal_title：Annals of surgical oncology

authors： Feldman DR,Kulling DP,Kay CL,Cole DJ,Cunningham JT,Hawes RH,Tarnasky PR,Cotton PB,Baron PL

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:Breast cancers (BCs) diagnosed after a recent pregnancy display features associated with poor prognosis, including hormone receptor negativity, but other tumor markers have not been examined. We sought to define the tumor marker profile of these cancers, including HER-2 and p53 expression, and examine the ti...

journal_title：Annals of surgical oncology

authors： Pilewskie M,Gorodinsky P,Fought A,Hansen N,Bethke K,Jeruss J,Scholtens D,Khan SA

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Accelerated partial breast irradiation (APBI) has gained widespread interest as a means of improving the convenience and availability of breast conserving radiotherapy. Intraoperative radiation therapy (IORT) is an APBI technique that delivers breast radiotherapy as a single dose at the time of partial maste...

journal_title：Annals of surgical oncology

authors： Ollila DW,Klauber-DeMore N,Tesche LJ,Kuzmiak CM,Pavic D,Goyal LK,Lian J,Chang S,Livasy CA,Sherron RF,Sartor CI

更新日期：2007-02-01 00:00:00

abstract：PURPOSE:With the exception of papillary and follicular thyroid cancer, malignant cancers of the thyroid, parathyroid, adrenal, and endocrine pancreas are uncommon. These rare malignancies present a challenge to both the clinician and patient, because few data exist on their incidence or survival. We analyzed the incide...

journal_title：Annals of surgical oncology

authors： James BC,Aschebrook-Kilfoy B,Cipriani N,Kaplan EL,Angelos P,Grogan RH

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Detection of cancer micrometastases is required for improvement of cancer therapy. The aim of this study was to establish a rapid and practical genetic assay to detect micrometastasis in gastric cancer and to assess its clinical significance with respect to prognosis. METHODS:A novel RNA amplification syste...

journal_title：Annals of surgical oncology

authors： Ishii T,Fujiwara Y,Ohnaka S,Hayashi T,Taniguchi H,Takiguchi S,Yasuda T,Yano M,Monden M

更新日期：2004-08-01 00:00:00

abstract：PURPOSE:The volume of surgical procedures performed by hospitals and surgeons has a strong influence on outcomes for a number of surgeries. We examined the influence of surgeon and hospital case volume on morbidity, mortality, and resource utilization for women with endometrial cancer undergoing laparoscopic hysterecto...

journal_title：Annals of surgical oncology

authors： Wright JD,Hershman DL,Burke WM,Lu YS,Neugut AI,Lewin SN,Herzog TJ

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The benefit of completion lymph node dissection (CLND) in melanoma patients with a positive sentinel lymph node (SLN) remains unknown. METHODS:We identified patients with a positive SLN from 1994 to 2012. Patient and tumor characteristics, reasons for not undergoing CLND, patterns of recurrence, and melanom...

journal_title：Annals of surgical oncology

authors： Bamboat ZM,Konstantinidis IT,Kuk D,Ariyan CE,Brady MS,Coit DG

更新日期：2014-09-01 00:00:00

abstract：: ...

journal_title：Annals of surgical oncology

authors： Turaga KK,Clark Gamblin T,Richard Alexander H,Edwards R,Bartlett DL

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:The combination of neoadjuvant radiochemotherapy and parenchyma-preserving sleeve resection for lung cancer remains controversial because of potentially increased rate of anastomotic breakdown. We analyzed the effects of applying a decellularized human dermis transplant seeded with autologous fibroblasts in ...

journal_title：Annals of surgical oncology

authors： Roessner E,Vitacolonna M,Schulmeister A,Pilz L,Tsagogiorgas C,Brockmann M,Hohenberger P

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Although an age cutoff of 45 years has often been adopted to stratify cancer risk in papillary thyroid carcinoma (PTC), both cancer-specific survival (CSS) and disease-specific survival (DFS) continue to worsen beyond this cutoff. This study aimed to determine whether advanced age (i.e., >60 years) at diagno...

journal_title：Annals of surgical oncology

authors： Lang BH,Lo CY,Wong KP,Wan KY

更新日期：2015-02-01 00:00:00

abstract：PURPOSE:Despite advances in therapy for the treatment of metastatic colorectal cancer, many patients die of hepatic disease. Current immunotherapeutic strategies are likely limited by inhibitory signals from the tumor. To successfully eliminate tumor deposits within an organ, an appropriate immunologic milieu to amplif...

journal_title：Annals of surgical oncology

authors： Olino K,Wada S,Edil BH,Pan X,Meckel K,Weber W,Slansky J,Tamada K,Lauer P,Brockstedt D,Pardoll D,Schulick R,Yoshimura K

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Current mammographic technology has resulted in increased detection of ductal carcinoma in situ (DCIS). It is necessary to assess which patients presenting with DCIS are good candidates for breast conservation and which of these patients should receive adjuvant radiation. METHODS:We accrued clinical data fo...

journal_title：Annals of surgical oncology

authors： Fish EB,Chapman JA,Miller NA,Link MA,Fishell E,Wright B,McCready DR,Hiraki GY,Ross TM,Hanna WM,Lickley HL

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:The optimal tumor-free margin width remains controversial and may be inappropriate to investigate without considering differences in the underlying tumor biology. METHODS:R1 resection was defined as margin clearance less than 1 mm. R0 resection was further divided into 3 groups: 1-4, 5-9, and ≥10 mm. The im...

journal_title：Annals of surgical oncology

authors： Margonis GA,Sasaki K,Andreatos N,Kim Y,Merath K,Wagner D,Wilson A,Buettner S,Amini N,Antoniou E,Pawlik TM

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The anti-tumor effects of three mouse mammary tumors transfected to express interleukin (IL) 2 or 4 were evaluated. METHODS:Three immunologically different tumors were used: DA3, EMT6, and 410. All three cell lines were successfully transfected using high efficiency viral vectors. Wild-type or transfected t...

journal_title：Annals of surgical oncology

authors： Matory YL,Chen M,Goedegebuure PS,Eberlein TJ

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:We present an alternative access technique to facilitate preperitoneoscopic (extraperitoneal laparoscopic) approach for radical prostatectomy, herniorrhaphy, and other pelvic procedures. METHODS:A 0 degrees telescope was mounted into a Visiport Optical Trocar (Visiport), and via a periumbilical incision it ...

journal_title：Annals of surgical oncology

authors： Tai HC,Lai MK,Chueh SC,Chen SC,Hsieh MH,Yu HJ

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:The goal of this study is to report the safety and efficacy of pancreatic resection for isolated metastatic cancers from nonpancreatic primary disease. METHODS:We retrospectively identified patients from a single institution's prospectively gathered pancreaticobiliary database from 1970 to 2007 who underwen...

journal_title：Annals of surgical oncology

authors： Reddy S,Edil BH,Cameron JL,Pawlik TM,Herman JM,Gilson MM,Campbell KA,Schulick RD,Ahuja N,Wolfgang CL

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVES:Atypical protein kinase C iota (aPKC-iota) and its associated intracellular molecules, E-cadherin and beta-catenin, are important for cell polarization in tumorigenesis and progression. Expression of aPKC-iota, P-aPKC-iota (activated aPKC-iota), E-cadherin, and beta-catenin in hepatocellular carcinoma (HCC) ...

journal_title：Annals of surgical oncology

authors： Du GS,Wang JM,Lu JX,Li Q,Ma CQ,Du JT,Zou SQ

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Sarcopenia influences overall survival (OS) and tumor progression in non-small cell lung cancer (NSCLC) patients. However, the impact of postoperative complications and the outcome of limited surgery have not been highlighted. Therefore, the aim of this study is to elucidate the prognostic impact of sarcopen...

journal_title：Annals of surgical oncology

authors： Shinohara S,Otsuki R,Kobayashi K,Sugaya M,Matsuo M,Nakagawa M

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:As increased focus is placed on quality of care in surgery, readmission is an increasingly important metric by which hospital and surgeon quality is measured. For complex pancreatic surgery, we hypothesized that increased pancreaticoduodenectomy (PD) volume may mitigate readmission rates. METHODS:The Univer...

journal_title：Annals of surgical oncology

authors： Sutton JM,Wilson GC,Wima K,Hoehn RS,Cutler Quillin R 3rd,Hanseman DJ,Paquette IM,Sussman JJ,Ahmad SA,Shah SA,Abbott DE

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:There is a continuous interest in the literature concerning the management and survival after treatment of local recurrence in sarcomas because it is one of the most common types of recurrence. DESIGN:We retrospectively reviewed 93 patients treated for local recurrence from soft-tissue sarcoma. METHODS:We ...

journal_title：Annals of surgical oncology

authors： Karakousis CP,Proimakis C,Rao U,Velez AF,Driscoll DL

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Preliminary data indicate that tyrosine kinase inhibitors (TKIs) function through rearranged during transfection (RET) in breast cancer. However, TKIs are not specific and can block several receptor tyrosine kinases (RTKs). This study used cell lines and primary breast cancer specimens to determine factors a...

journal_title：Annals of surgical oncology

authors： Spanheimer PM,Lorenzen AW,De Andrade JP,Kulak MV,Carr JC,Woodfield GW,Sugg SL,Weigel RJ

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The transcription factor NF-E2-related factor 2 (Nrf2) was originally identified to be a critical regulator of intracellular antioxidants and phase II detoxification enzymes. Recent studies have shown that high Nrf2 expression gives cancer cells an advantage for survival from anticancer chemotherapy and radi...

journal_title：Annals of surgical oncology

authors： Kawasaki Y,Okumura H,Uchikado Y,Kita Y,Sasaki K,Owaki T,Ishigami S,Natsugoe S

更新日期：2014-07-01 00:00:00