Observation after a positive sentinel lymph node biopsy in patients with melanoma.

abstract：BACKGROUND:To improve the poor prognosis of patients with advanced incurable gastric cancer, intensive chemotherapy combined with radical surgery was used. PATIENTS AND METHODS:Thirty patients with incurable gastric cancer were treated with a combination of 5-fluorouracil (370 mg/m2) and leucovorin (30 mg/person), giv...

journal_title：Annals of surgical oncology

authors： Nakajima T,Ota K,Ishihara S,Oyama S,Nishi M,Ohashi Y,Yanagisawa A

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Distal pancreatectomy with celiac axis resection (DP-CAR) is a treatment option for selected patients with pancreatic cancer involving the celiac axis. A recent multicenter European study reported a 90-day mortality rate of 16%, highlighting the importance of patient selection. The authors constructed a risk...

journal_title：Annals of surgical oncology

authors： Klompmaker S,Peters NA,van Hilst J,Bassi C,Boggi U,Busch OR,Niesen W,Van Gulik TM,Javed AA,Kleeff J,Kawai M,Lesurtel M,Lombardo C,Moser AJ,Okada KI,Popescu I,Prasad R,Salvia R,Sauvanet A,Sturesson C,Weiss MJ,Zeh

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Health care reform places primary care (PC) physicians in an increasingly significant role for breast cancer screening and diagnosis. This study assessed the adequacy of traditional PC resident training to prepare physicians for this front-line role. METHODS:Sixty-eight primary care residents, representing ...

journal_title：Annals of surgical oncology

authors： Chalabian J,Formenti S,Russell C,Pearce J,Dunnington G

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Histologic grade, TNM stage, and Nottingham Prognostic Index are traditional prognostic tools for breast cancer. "IHC-molecular" classification of breast cancer can also identify patients at different recurrence risks and provides insight into cancer therapy. However, cancers in each group are heterogeneous....

journal_title：Annals of surgical oncology

authors： Ni YB,Tsang JY,Chan SK,Tse GM

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Genetic and epigenetic alterations during development of pancreatic ductal adenocarcinomas (PDAC) are well known. Genetic and epigenetic data were correlated with tumor biology to find specific alterations responsible for invasion and metastasis in pancreatic ductal adenocarcinomas. METHODS:A total of 16 hu...

journal_title：Annals of surgical oncology

authors： Mees ST,Mardin WA,Sielker S,Willscher E,Senninger N,Schleicher C,Colombo-Benkmann M,Haier J

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Understanding the natural progression of untreated gastric cancer is critical for determining the disease prognosis as well as treatment options and timing. The aim of this study is to analyze the natural history of gastric cancer. PATIENTS AND METHODS:We included patients with gastric cancer who had not re...

journal_title：Annals of surgical oncology

authors： Oh SY,Lee JH,Lee HJ,Kim TH,Huh YJ,Ahn HS,Suh YS,Kong SH,Kim GH,Ahn SJ,Kim SH,Choi Y,Yang HK

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:With the recent development of molecular markers, it has become possible to characterize colorectal carcinomas beyond clinical and histologic aspects. When considered together with tumor stage, molecular markers will allow us further insight into individual tumor biologies and prognoses. PURPOSE:To investig...

journal_title：Annals of surgical oncology

authors： Kang H,Min BS,Lee KY,Kim NK,Kim SN,Choi J,Kim H

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The relation of dialysis to tumor recurrence in patients with upper tract urothelial cancer (UTUC) is unknown; however, a limited number of small-scale studies suggest that patients with renal diseases prior to UTUC are more likely to exhibit bladder recurrence. We performed a population-based analysis to de...

journal_title：Annals of surgical oncology

authors： Lin MY,Li WM,Huang CN,Lee HL,Niu SW,Chen LT,Wu WJ,Hwang SJ

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Primary breast cancers that overexpress human epidermal growth factor receptor 2 have variable biological features and clinical outcomes. A subgroup of HER2-overexpressing tumors that express basal-like immunohistochemical markers-the so-called basal-HER2+ subtype--is associated with poor prognosis. We inves...

journal_title：Annals of surgical oncology

authors： Bagaria SP,Ray PS,Wang J,Kropcho L,Chung A,Sim MS,Shamonki JM,Martino S,Cui X,Giuliano AE

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Heat-shock protein gp96 plays an important role in antitumor immunoreactions. Gp96 has a close relationship with antitumor immunity. This study evaluated the correlation between gp96 expression and the prognosis in esophageal squamous cell carcinoma. METHODS:Seventy-eight patients with primarily resected es...

journal_title：Annals of surgical oncology

authors： Akutsu Y,Matsubara H,Kano M,Usui A,Yoneyama Y,Ikeda N,Komatsu A,Yusup G

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Dendritic cells (DC) are potent professional antigen-presenting cells that can activate naive T lymphocytes and initiate cellular immune responses. As adjuvants, DC may be useful for enhancing immunogenicity and mediating tumor regression. Endogenous expression of antigen by DC could offer the potential adva...

journal_title：Annals of surgical oncology

authors： Kim CJ,Cormier J,Roden M,Gritz L,Mazzara GP,Fetsch P,Hijazi Y,Lee KH,Rosenberg SA,Marincola FM

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Studies assessing outcomes in occult breast cancer have often included women treated before the routine use of magnetic resonance imaging (MRI). This study examined outcomes for patients presenting with axillary adenopathy and no primary breast tumor detectable by MRI or other imaging methods. METHODS:All p...

journal_title：Annals of surgical oncology

authors： McCartan DP,Zabor EC,Morrow M,Van Zee KJ,El-Tamer MB

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:The decision to receive adjuvant chemotherapy is far from evident and remains controversial in patients with American Joint Committee on Cancer stage II colon cancer. This study analyzes several pathological characteristics in order to assess their (combined) predictive value for outcomes in stage II colon c...

journal_title：Annals of surgical oncology

authors： Amri R,England J,Bordeianou LG,Berger DL

更新日期：2016-11-01 00:00:00

abstract：:Breast surgery has evolved as a subspecialty of general surgery and requires a working knowledge of benign and malignant diseases, surgical techniques, shared decision-making with patients, collaboration with a multi-disciplinary team, and a basic foundation in surgical ethics. Ethics is defined as the practice of ana...

journal_title：Annals of surgical oncology

authors： Throckmorton A,VanderWalde L,Brackett C,Dominici L,Eisenhauer T,Johnson N,Kong A,Ludwig K,O'Neill J,Pugliese M,Teller P,Sarantou T

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Sentinel lymph node mapping (SLNM) and neoadjuvant chemotherapy are becoming established components of therapy for selected patients with breast carcinoma. However, neoadjuvant therapy has been considered a relative contraindication to SLNM. In an effort to learn whether patients who have received preoperati...

journal_title：Annals of surgical oncology

authors： Miller AR,Thomason VE,Yeh IT,Alrahwan A,Sharkey FE,Stauffer J,Otto PM,McKay C,Kahlenberg MS,Phillips WT,Cruz AB Jr

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Functional chemokine receptors are expressed in many malignant tumors, including papillary thyroid carcinoma (PTC). These receptors promote tumor growth and metastasis in response to endogenous chemokines. The purpose of this study was to examine the expression of two chemokine receptors-CXCR4 and CCR7-in a ...

journal_title：Annals of surgical oncology

authors： Wagner PL,Moo TA,Arora N,Liu YF,Zarnegar R,Scognamiglio T,Fahey TJ 3rd

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Despite data from randomized trials supporting omission of radiation therapy (RT) for women ≥ 70 years of age with T1, estrogen receptor-positive (ER+) tumors undergoing breast-conserving therapy (BCT), RT usage remains high. We reviewed our institutional experience to determine if risk factors for local rec...

journal_title：Annals of surgical oncology

authors： Downs-Canner S,Zabor EC,Wind T,Cobovic A,McCormick B,Morrow M,Heerdt A

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Extracapsular invasion (ECI) of metastatic axillary lymph nodes has been associated with aggressive nodal disease but its prognostic role in breast cancer is unclear. The present study evaluated nodal ECI as a predictor of breast cancer recurrence. METHODS:We evaluated 154 women with histologically proven n...

journal_title：Annals of surgical oncology

authors： Yajima R,Fujii T,Yanagita Y,Fujisawa T,Miyamoto T,Hirakata T,Tsutsumi S,Iijima M,Kuwano H

更新日期：2015-01-01 00:00:00

abstract：:Cervical cancer incidence and mortality have declined in developed countries during the past few decades as a result of screening programs and vaccination. However, it remains a significant cause of cancer-related mortality in young women. Early-stage cervical cancer, defined as disease limited to the cervix, has trad...

journal_title：Annals of surgical oncology

authors： Basaran D,Leitao MM Jr

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Intraperitoneal chemotherapy is used to treat peritoneal surface-spreading malignancies. We sought to determine whether volume and surface area of the intraperitoneal chemotherapy compartments are associated with overall survival and posttreatment glomerular filtration rate (GFR) in malignant peritoneal meso...

journal_title：Annals of surgical oncology

authors： Leinwand JC,Zhao B,Guo X,Krishnamoorthy S,Qi J,Graziano JH,Slavkovic VN,Bates GE,Lewin SN,Allendorf JD,Chabot JA,Schwartz LH,Taub RN

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Abnormal phosphatase and tensin analog (PTEN) gene expression has been noted in neoplasms. The PTEN protein cleaves phosphate groups from cellular growth kinases, inhibiting tumor propagation. A downstream target of PTEN is AKT, a serine-threonine kinase that when activated inhibits apoptosis. We sought to d...

journal_title：Annals of surgical oncology

authors： Mohiuddin I,Cao X,Ozvaran MK,Zumstein L,Chada S,Smythe WR

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Lateral lymph node dissection (LND) in the absence of macroscopic nodal metastasis remains controversial in sporadic medullary thyroid carcinoma (MTC). OBJECTIVES:The aims of our study were to determine the risk of lateral lymph node (LN) metastases with a focus on lateral contralateral N1, and to define a ...

journal_title：Annals of surgical oncology

authors： Chandeze MM,Noullet S,Faron M,Trésallet C,Godiris-Petit G,Tissier F,Buffet C,Leenhardt L,Chereau N,Menegaux F

更新日期：2016-10-01 00:00:00

abstract：INTRODUCTION:Retroperitoneal soft tissue sarcomas (RPSs) are mesenchymal neoplasms. The prevalence of protein energetic malnutrition (PEM) and its impact in RPS patients who were candidates for surgery is unknown. MATERIALS AND METHODS:A prospective feasibility study enrolled 35 patients with primary RPS who were cand...

journal_title：Annals of surgical oncology

authors： Previtali P,Fiore M,Colombo J,Arendar I,Fumagalli L,Pizzocri M,Colombo C,Rampello NN,Mariani L,Gronchi A,Codazzi D

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Autophagy plays a major role in cellular homeostasis and is implicated in cancer progression. Damaged mitochondria are scavenged and eliminated by mitochondrial autophagy, referred to as mitophagy, which can promote cancer cell survival. This study investigated the expression and effects of the autophagy-rel...

journal_title：Annals of surgical oncology

authors： Yamashita K,Miyata H,Makino T,Masuike Y,Furukawa H,Tanaka K,Miyazaki Y,Takahashi T,Kurokawa Y,Yamasaki M,Nakajima K,Takiguchi S,Morii E,Mori M,Doki Y

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The inability to visualize the patient and surgical site directly, limits the use of current near infrared fluorescence-guided surgery systems for real-time sentinel lymph node biopsy and tumor margin assessment. METHODS:We evaluated an optical see-through goggle augmented imaging and navigation system (GAI...

journal_title：Annals of surgical oncology

authors： Mondal SB,Gao S,Zhu N,Habimana-Griffin L,Akers WJ,Liang R,Gruev V,Margenthaler J,Achilefu S

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Intraoperative analysis of sentinel lymph nodes would enhance the care of early-stage oral squamous cell carcinoma (OSCC). We determined the frequency and extent of cytokeratin 19 (CK19) expression in OSCC primary tumours and surrounding tissues to explore the feasibility of a "clinic-ready" intraoperative d...

journal_title：Annals of surgical oncology

authors： Shaw R,Christensen A,Java K,Maddani RE,Liloglou T,Asterios T,von Buchwald C,Wessel I,Kiss K,Kjaer A,Lelkaitis G,Long A,Risk J,Robinson M

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Patients undergoing cytoreductive surgery for colorectal peritoneal metastases who have a pathologic complete response (pCR) to neoadjuvant chemotherapy experience a significantly longer survival than those with residual disease. This response is known only after surgery. This study aimed to examine clinical...

journal_title：Annals of surgical oncology

authors： Bhatt A,Rousset P,Benzerdjeb N,Kammar P,Mehta S,Parikh L,Goswami G,Shaikh S,Kepenekian V,Passot G,Glehen O

更新日期：2020-11-18 00:00:00

abstract：BACKGROUND:This study was designed to describe patient, disease, and treatment characteristics of women diagnosed with breast cancer at the Breast Examination Center of Harlem (BECH) and to determine whether these characteristics have changed over time. METHODS:Retrospective chart review of women diagnosed with breast...

journal_title：Annals of surgical oncology

authors： Manning AT,Eaton A,Azu M,Sampson M,Patil S,Godfrey D,Beesen AA,Liberman L,Gemignani ML

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Extraskeletal myxoid chondrosarcoma (EMC) is a rare sarcoma of uncertain origin, marked by specific chromosomal translocations involving the NR4A3 gene, and usually characterized by an indolent course. Surgery (with or without radiotherapy) is the treatment of choice in localized disease. The treatment for a...

journal_title：Annals of surgical oncology

authors： Paioli A,Stacchiotti S,Campanacci D,Palmerini E,Frezza AM,Longhi A,Radaelli S,Donati DM,Beltrami G,Bianchi G,Barisella M,Righi A,Benini S,Fiore M,Picci P,Gronchi A

更新日期：2021-02-01 00:00:00

abstract：PURPOSE:Treatment of synovial sarcoma (SS) is challenging because of its unpredictable clinical behavior. We reviewed our institutional experience with pediatric SS to identify prognostic indicators and survival outcomes. METHODS:We retrospectively reviewed all pediatric/adolescent patients (age<22 years) with confirm...

journal_title：Annals of surgical oncology

authors： Stanelle EJ,Christison-Lagay ER,Healey JH,Singer S,Meyers PA,La Quaglia MP

更新日期：2013-01-01 00:00:00