Quantitative X-ray computed tomography peritoneography in malignant peritoneal mesothelioma patients receiving intraperitoneal chemotherapy.

Abstract:

BACKGROUND:Intraperitoneal chemotherapy is used to treat peritoneal surface-spreading malignancies. We sought to determine whether volume and surface area of the intraperitoneal chemotherapy compartments are associated with overall survival and posttreatment glomerular filtration rate (GFR) in malignant peritoneal mesothelioma (MPM) patients. METHODS:Thirty-eight MPM patients underwent X-ray computed tomography peritoneograms during outpatient intraperitoneal chemotherapy. We calculated volume and surface area of contrast-filled compartments by semiautomated computer algorithm. We tested whether these were associated with overall survival and posttreatment GFR. RESULTS:Decreased likelihood of mortality was associated with larger surface areas (p = 0.0201) and smaller contrast-filled compartment volumes (p = 0.0341), controlling for age, sex, histologic subtype, and presence of residual disease >0.5 cm postoperatively. Larger volumes were associated with higher posttreatment GFR, controlling for pretreatment GFR, body surface area, surface area, and the interaction between body surface area and volume (p = 0.0167). DISCUSSION:Computed tomography peritoneography is an appropriate modality to assess for maldistribution of intraperitoneal chemotherapy. In addition to identifying catheter failure and frank loculation, quantitative analysis of the contrast-filled compartment's surface area and volume may predict overall survival and cisplatin-induced nephrotoxicity. Prospective studies should be undertaken to confirm and extend these findings to other diseases, including advanced ovarian carcinoma.

journal_name

Ann Surg Oncol

authors

Leinwand JC,Zhao B,Guo X,Krishnamoorthy S,Qi J,Graziano JH,Slavkovic VN,Bates GE,Lewin SN,Allendorf JD,Chabot JA,Schwartz LH,Taub RN

doi

10.1245/s10434-013-2976-8

subject

Has Abstract

pub_date

2013-12-01 00:00:00

pages

S553-9

eissn

1068-9265

issn

1534-4681

journal_volume

20 Suppl 3

pub_type

杂志文章
  • Survival among patients with platinum resistant, locally advanced non-small cell lung cancer treated with platinum-based systemic therapy.

    abstract:BACKGROUND:Recent adjuvant chemotherapy trials after resection of stage II and III non-small cell lung cancer (NSCLC) have identified important survival differences among patients with immunohistochemical evidence suggesting platinum resistance. No clinical information exists regarding the impact upon survival of patie...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-009-0608-0

    authors: d'Amato TA,Pettiford BL,Schuchert MJ,Parker R,Ricketts WA,Luketich JD,Landreneau RJ

    更新日期:2009-10-01 00:00:00

  • Exploring the Spatial Drug Distribution Pattern of Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC).

    abstract:BACKGROUND:Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel approach to delivering intraperitoneal chemotherapy (IPC) as a pressurized aerosol. One of the assumed advantages is the homogeneous drug distribution in the intraperitoneal cavity compared with conventional liquid in situ chemotherapy. Howe...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-015-4954-9

    authors: Khosrawipour V,Khosrawipour T,Diaz-Carballo D,Förster E,Zieren J,Giger-Pabst U

    更新日期:2016-04-01 00:00:00

  • Evaluation of Lymph Node Staging Systems as Independent Prognosticators in Remnant Gastric Cancer Patients with an Insufficient Number of Harvested Lymph Nodes.

    abstract:BACKGROUND:The lymph node (LN) ratio (LNR) and the log odds of positive LNs (LODDS) have been proposed as sensitive prognosticators in patients with primary gastric cancer, especially in patients with an insufficient number of harvested LNs. We investigated the association of LNR and LODDS with survival in patients wit...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-020-09433-2

    authors: Kano K,Yamada T,Yamamoto K,Komori K,Watanabe H,Takahashi K,Maezawa Y,Fujikawa H,Numata M,Aoyama T,Tamagawa H,Cho H,Yukawa N,Yoshikawa T,Rino Y,Masuda M,Ogata T,Oshima T

    更新日期:2021-01-03 00:00:00

  • Prognostic value of cytokeratin-positive bone marrow cells of gastric cancer patients.

    abstract:BACKGROUND:Epithelial cells in the bone marrow of patients with gastric cancer suggest tumor dissemination; however, their prognostic implications are controversial. We prospectively evaluated the correlation of bone marrow findings, recurrence rate, and disease-free survival after long-term follow-up. METHODS:Bone ma...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-006-9039-3

    authors: Gretschel S,Schick C,Schneider U,Estevez-Schwarz L,Bembenek A,Schlag PM

    更新日期:2007-02-01 00:00:00

  • The Prognostic Significance of the Oncotype DX Recurrence Score in T1-2N1M0 Estrogen Receptor-Positive HER2-Negative Breast Cancer Based on the Prognostic Stage in the Updated AJCC 8th Edition.

    abstract:BACKGROUND:This study aimed to evaluate the prognostic significance of the Oncotype DX recurrence score (RS) in T1-2N1M0 estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer based on the prognostic stage in the updated American Joint Commission on Cancer, 8th edition. ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-018-7068-3

    authors: Wang M,Wu K,Zhang P,Zhang M,Ding A,Chen H

    更新日期:2019-05-01 00:00:00

  • Pitfalls of positive findings in staging esophageal cancer with F-18-fluorodeoxyglucose positron emission tomography.

    abstract:BACKGROUND:18-F-fluorodeoxyglucose positron emission tomography (FDG-PET) is valuable in staging of esophageal cancer. However, FDG-PET may falsely upstage patients leading to incorrect exclusion from surgical treatment. This study was performed to determine the false-positive rate and possible causes. METHODS:The rat...

    journal_title:Annals of surgical oncology

    pub_type: 临床试验,杂志文章

    doi:10.1245/aso.2003.03.005

    authors: van Westreenen HL,Heeren PA,Jager PL,van Dullemen HM,Groen H,Plukker JT

    更新日期:2003-11-01 00:00:00

  • ASO Author Reflections: Omentoplasty to Improve Perineal Wound Healing After Abdominoperineal Resection.

    abstract:: ...

    journal_title:Annals of surgical oncology

    pub_type: 评论,杂志文章

    doi:10.1245/s10434-018-6799-5

    authors: Blok RD,Tanis PJ

    更新日期:2018-12-01 00:00:00

  • Learning curve for percutaneous radiofrequency ablation of pulmonary metastases from colorectal carcinoma: a prospective study of 70 consecutive cases.

    abstract:BACKGROUND:Percutaneous radiofrequency ablation (RFA) for inoperable colorectal pulmonary metastases is associated with a morbidity rate of 30% to 40%. A learning curve in this treatment approach has not been documented before. METHODS:The clinical and treatment-related data regarding 70 consecutive percutaneous RFA p...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-006-9010-3

    authors: Yan TD,King J,Sjarif A,Glenn D,Steinke K,Morris DL

    更新日期:2006-12-01 00:00:00

  • Knockdown of thrombomodulin enhances HCC cell migration through increase of ZEB1 and decrease of E-cadherin gene expression.

    abstract:BACKGROUND:Thrombomodulin (TM) is a key molecule mediating circulation homeostasis through its binding to thrombin. The TM-thrombin complex can activate protein C and thrombin-activatable fibrinolysis inhibitor to form a tight clot. In many cancer tissues, decrease of TM expression may correlate with cancer metastasis....

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-010-1163-4

    authors: Huang MT,Wei PL,Liu JJ,Liu DZ,Huey-Chun H,An J,Wu CC,Wu CH,Ho YS,Yang YY,Chang YJ

    更新日期:2010-12-01 00:00:00

  • Two subtypes of mucinous adenocarcinoma of the colorectum: clinicopathological and genetic features.

    abstract:BACKGROUND:This work is aimed at comparing mucinous colorectal adenocarcinomas (MUC) and non-mucinous colorectal adenocarcinomas (non-MUC), and at verifying the existence of two different subgroups of MUC, in terms of clinicopathological features, chromosomal alterations, and outcome, in a geographical area where mucin...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-007-9757-1

    authors: Leopoldo S,Lorena B,Cinzia A,Gabriella DC,Angela Luciana B,Renato C,Antonio M,Carlo S,Cristina P,Stefano C,Maurizio T,Luigi R,Cesare B

    更新日期:2008-05-01 00:00:00

  • Lobe-Specific Lymph Node Dissection for Clinical Early-Stage (cIA) Peripheral Non-small Cell Lung Cancer Patients: What and How?

    abstract:OBJECTIVE:We investigated the possible lobe-specific lymph node (LN) metastasis pattern of early-stage peripheral non-small cell lung cancers (NSCLC) and define the extent of lobe-specific LN dissection for them. METHODS:We retrospectively collected clinical data of patients undergoing lobectomy or segmentectomy with ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-019-07926-3

    authors: Deng HY,Zhou J,Wang RL,Jiang R,Zhu DX,Tang XJ,Zhou Q

    更新日期:2020-02-01 00:00:00

  • Sentinel node dissection delays recurrence and prolongs melanoma-related survival: an analysis of 673 patients from a single center with long-term follow-up.

    abstract:BACKGROUND:The status of the sentinel lymph node is an important predictor for survival in melanoma patients, but it is still unclear if early removal of micrometastases by sentinel lymph node dissection (SLND) alters survival. A large series of melanoma patients from a single center with long-term follow-up was analyz...

    journal_title:Annals of surgical oncology

    pub_type: 临床试验,杂志文章

    doi:10.1245/s10434-010-1318-3

    authors: Satzger I,Meier A,Hoy L,Völker B,Kapp A,Hauschild A,Gutzmer R

    更新日期:2011-02-01 00:00:00

  • Optimal Cutoff Values of Skeletal Muscle Index to Define Sarcopenia for Prediction of Survival in Patients with Advanced Gastric Cancer.

    abstract:BACKGROUND:Sarcopenia, characterized by loss of skeletal muscle mass, is recognized as a prognostic factor in patients with gastric cancer. However, wide variability exists in the cutoff values of muscle mass for defining sarcopenia across previous studies, and the best cutoff values to predict survival remain unknown....

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-018-6728-7

    authors: Nishigori T,Tsunoda S,Obama K,Hisamori S,Hashimoto K,Itatani Y,Okada K,Sakai Y

    更新日期:2018-11-01 00:00:00

  • Multivisceral resection does not affect morbidity and survival after cytoreductive surgery and chemoperfusion for carcinomatosis from colorectal cancer.

    abstract:BACKGROUND:Carcinomatosis of colorectal origin is increasingly treated by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CS-HIPEC). This procedure commonly involves multivisceral resection (MVR) with potentially high morbidity. We analyzed the effect of MVR on the outcome after CS-HIPEC. METHODS:...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-008-0105-x

    authors: Franko J,Gusani NJ,Holtzman MP,Ahrendt SA,Jones HL,Zeh HJ 3rd,Bartlett DL

    更新日期:2008-11-01 00:00:00

  • Intraoperative examination of sentinel nodes in breast cancer: is the glass half full or half empty?

    abstract:BACKGROUND:Intraoperative identification of positive sentinel lymph nodes in patients with breast cancer may avoid a return to the operating room. METHODS:In a group of 402 consecutive patients with primary breast cancer who underwent sentinel lymph node biopsy, an intraoperative examination (IE) was obtained in 236 c...

    journal_title:Annals of surgical oncology

    pub_type: 临床试验,杂志文章

    doi:10.1245/ASO.2004.12.005

    authors: Fortunato L,Amini M,Farina M,Rapacchietta S,Costarelli L,Piro FR,Alessi G,Pompili P,Bianca S,Vitelli CE

    更新日期:2004-11-01 00:00:00

  • Pathologic Complete Response Rates After Neoadjuvant Treatment in Rectal Cancer: An Analysis of the National Cancer Database.

    abstract:BACKGROUND:Pathologic complete response (pCR) of rectal cancer following neoadjuvant therapy is associated with decreased local recurrence and increased overall survival. This study utilizes a national dataset to identify predictors of pCR in patients with rectal cancer. METHODS:The National Cancer Database was querie...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-017-5873-8

    authors: Lorimer PD,Motz BM,Kirks RC,Boselli DM,Walsh KK,Prabhu RS,Hill JS,Salo JC

    更新日期:2017-08-01 00:00:00

  • Rate of Occult Neck Nodal Metastasis in Parotid Cancer: A Meta-Analysis.

    abstract:BACKGROUND:The risk for occult neck nodal metastasis in carcinoma of the parotid gland is inconclusive. Therefore, addressing a negative neck prophylactically and the extent to do so remain controversial. This systematic review aimed to determine the rate of occult nodal metastasis for each neck level, and consequently...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1245/s10434-020-09331-7

    authors: Warshavsky A,Rosen R,Muhanna N,Ungar O,Nard-Carmel N,Abergel A,Fliss DM,Horowitz G

    更新日期:2020-11-11 00:00:00

  • Tumor proximity to the recurrent laryngeal nerve in patients with primary hyperparathyroidism undergoing parathyroidectomy.

    abstract:BACKGROUND:Recurrent laryngeal nerve (RLN) injury is a rare complication for patients undergoing neck exploration for primary hyperparathyroidism (pHPT). Distances between RLNs and parathyroid adenomas have not been previously published. In this study we used a RLN monitor to identify the RLN and to measure the proximi...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-012-2495-z

    authors: Untch BR,Adam MA,Danko ME,Barfield ME,Dixit D,Scheri RP,Olson JA

    更新日期:2012-11-01 00:00:00

  • Utility of Chemoresponse Assay in Patients Undergoing Cytoreductive Surgery Plus Hyperthermic Intraperitoneal Chemotherapy.

    abstract:PURPOSE:Our aim was to evaluate the utility of in vitro drug sensitivity testing in patients with peritoneal surface malignancies undergoing cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC). METHODS:We found data for 27 patients who underwent CRS plus HIPEC from September 2009 to May ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-014-4330-1

    authors: Bhagwandin S,Naffouje S,Salti G

    更新日期:2015-08-01 00:00:00

  • Expression of P-aPKC-iota, E-cadherin, and beta-catenin related to invasion and metastasis in hepatocellular carcinoma.

    abstract:OBJECTIVES:Atypical protein kinase C iota (aPKC-iota) and its associated intracellular molecules, E-cadherin and beta-catenin, are important for cell polarization in tumorigenesis and progression. Expression of aPKC-iota, P-aPKC-iota (activated aPKC-iota), E-cadherin, and beta-catenin in hepatocellular carcinoma (HCC) ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-009-0423-7

    authors: Du GS,Wang JM,Lu JX,Li Q,Ma CQ,Du JT,Zou SQ

    更新日期:2009-06-01 00:00:00

  • Prospective evaluation of laparoscopic celiac plexus block in patients with unresectable pancreatic adenocarcinoma.

    abstract:INTRODUCTION:The efficacy of laparoscopic celiac plexus block (CPB) in patients with unresectable pancreatic cancer has not been reported. METHODS:Patients with elevated pain scores scheduled for laparoscopy for diagnosis/staging of unresectable pancreatic adenocarcinoma were eligible. The study was designed to evalua...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-010-1372-x

    authors: Allen PJ,Chou J,Janakos M,Strong VE,Coit DG,Brennan MF

    更新日期:2011-03-01 00:00:00

  • Sentinel lymph node biopsy in pediatric and adolescent cutaneous melanoma patients.

    abstract:BACKGROUND:The rarity of melanoma in young patients, particularly pediatric ones, has to date precluded any valid comparisons being made between young patients and adults undergoing sentinel lymph node biopsy (SLNB) for intermediate thickness localized melanoma. The present study takes advantage of the large Sydney Mel...

    journal_title:Annals of surgical oncology

    pub_type: 临床试验,杂志文章

    doi:10.1245/s10434-009-0657-4

    authors: Howman-Giles R,Shaw HM,Scolyer RA,Murali R,Wilmott J,McCarthy SW,Uren RF,Thompson JF

    更新日期:2010-01-01 00:00:00

  • Salvage treatment for isolated regional failure of nasopharyngeal carcinoma after primary radiotherapy.

    abstract:BACKGROUND:Isolated regional failure of nasopharyngeal carcinoma (NPC) after primary treatment is traditionally treated with radical neck dissection (RND). The roles of modified radical neck dissection (MRND) and postoperative radiotherapy after salvage surgery currently remain unclear. METHODS:Medical records from ou...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-011-2018-3

    authors: Lo WC,Wang CP,Ko JY,Lou PJ,Yang TL,Wang CW,Hu YL,Chen TC

    更新日期:2012-03-01 00:00:00

  • Efficacy of different technical procedures for sentinel lymph node biopsy in gastric cancer staging.

    abstract:BACKGROUND:The clinical impact of sentinel lymph node biopsy (SLNB) in gastric cancer is controversial. We performed a prospective trial to compare different methods: radiocolloid method (RM), dye method (DM), and both methods simultaneously (dual method, or DUM) for reliability and therapeutic consequences. METHODS:R...

    journal_title:Annals of surgical oncology

    pub_type: 临床试验,杂志文章

    doi:10.1245/s10434-007-9367-y

    authors: Gretschel S,Bembenek A,Hünerbein M,Dresel S,Schneider W,Schlag PM

    更新日期:2007-07-01 00:00:00

  • Verification of the Optimal Interval Before Esophagectomy After Preoperative Neoadjuvant Chemoradiotherapy for Locally Advanced Thoracic Esophageal Cancer.

    abstract:BACKGROUND:The interval between preoperative chemoradiotherapy and surgery reportedly affects perioperative outcomes and survival; however, the optimal interval in esophageal cancer patients remains uncertain. OBJECTIVE:Our aim was to determine whether a prolonged interval between preoperative neoadjuvant chemoradioth...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-020-09206-x

    authors: Wakita A,Motoyama S,Sato Y,Nagaki Y,Fujita H,Terata K,Imai K,Minamiya Y

    更新日期:2020-10-13 00:00:00

  • Contralateral Prophylactic Mastectomy: Factors Predictive of Occult Malignancy or High-Risk Lesion and the Impact of MRI and Genetic Testing.

    abstract:BACKGROUND:Despite decreasing rates of subsequent contralateral breast cancer after diagnosis of unilateral primary breast cancer, the proportion of patients electing contralateral prophylactic mastectomy (CPM) is increasing. Our aim was to identify risk factors associated with the identification of occult malignancy (...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-015-4660-7

    authors: Erdahl LM,Boughey JC,Hoskin TL,Degnim AC,Hieken TJ

    更新日期:2016-01-01 00:00:00

  • Management of symptomatic malignant melanoma of the gastrointestinal tract.

    abstract:BACKGROUND:Melanoma metastatic to the gastrointestinal (GI) tract is asymptomatic or presents with pain, bleeding, or obstruction. To determine whether surgery influences outcomes, we reviewed our experience with this patient population. METHODS:Medical records of patients with metastatic melanoma to the GI tract were...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1007/s10434-999-0155-8

    authors: Berger AC,Buell JF,Venzon D,Baker AR,Libutti SK

    更新日期:1999-03-01 00:00:00

  • Adverse outcomes associated with noncompliance with melanoma treatment guidelines.

    abstract:BACKGROUND:Clinical practice guidelines have been developed to improve melanoma patient care. However, it is unclear whether failure to comply with these standards (either excessive or inadequate treatment) increases morbidity or relapse rates. Therefore, we undertook this study to evaluate the effect of variance from ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-008-0021-0

    authors: Erickson Foster J,Velasco JM,Hieken TJ

    更新日期:2008-09-01 00:00:00

  • Current issues in adjuvant treatment of stage II colon cancer.

    abstract:BACKGROUND:Adjuvant chemotherapy with 5-fluorouracil modulated by folinic acid, combined with oxaliplatin, has now become an accepted standard of care for patients with stage III colon cancer. In contrast, the use of adjuvant therapy for stage II patients remains controversial, and the identification of reliable progno...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1245/ASO.2006.07.003

    authors: André T,Sargent D,Tabernero J,O'Connell M,Buyse M,Sobrero A,Misset JL,Boni C,de Gramont A

    更新日期:2006-06-01 00:00:00

  • Radioguided parathyroidectomy in patients with familial hyperparathyroidism.

    abstract:BACKGROUND:In patients with sporadic hyperparathyroidism (HPT), radioguided parathyroidectomy (RGP) has been shown to facilitate intraoperative localization of parathyroid glands, reduced operative time, and improve patient outcomes. No studies have focused on the role of RGP in patients with familial HPT. METHODS:Bet...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-006-9254-y

    authors: Lal A,Bianco J,Chen H

    更新日期:2007-02-01 00:00:00