Expression of P-aPKC-iota, E-cadherin, and beta-catenin related to invasion and metastasis in hepatocellular carcinoma.

abstract：BACKGROUND:This study was conducted to investigate whether annual surgical unit caseload affects extent of breast cancer surgery, breast cancer recurrence or breast cancer-specific survival. METHODS:In a population-based cohort study, 12,604 women diagnosed with breast cancer in Finland during the years 1998-2001 were...

journal_title：Annals of surgical oncology

authors： Peltoniemi P,Peltola M,Hakulinen T,Häkkinen U,Pylkkänen L,Holli K

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:We performed a multicenter phase II study on the efficacy and safety of intraoperative radiotherapy (IORT) as partial breast irradiation using multiple devices. METHODS:The primary endpoint was ipsilateral breast tumor recurrence (IBTR). Key inclusion criteria were T < 2.5 cm, age > 50 years, surgical margi...

journal_title：Annals of surgical oncology

authors： Sawaki M,Miyamoto T,Fujisawa T,Itoh Y,Ebara T,Tachibana H,Kodaira T,Kikumori T,Yanagita Y,Iwata H

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:The role of supplemental oxygen therapy in the healing of esophagojejunal anastomosis is still very much in an experimental stage. The aim of the present prospective, randomized study was to assess the effect of administration of perioperative supplemental oxygen therapy on esophagojejunal anastomosis, where...

journal_title：Annals of surgical oncology

authors： Schietroma M,Cecilia EM,Carlei F,Sista F,De Santis G,Piccione F,Amicucci G

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:To evaluate the cost-efficacy of vacuum-assisted ultrasound-guided breast biopsy instruments compared to ultrasound-guided 14-gauge spring-loaded core-needle biopsy. METHODS:The American Society of Breast Surgeons' Mastery of Breast Surgery Registry was reviewed. Biopsy findings, any rebiopsy, and the instrume...

journal_title：Annals of surgical oncology

authors： Grady I,Vasquez T,Tawfik S,Grady S

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Subtotal thyroidectomy or lobectomy without radioactive iodide ((131)I) treatment is sufficient for postoperative treatment of incidental papillary thyroid microcarcinoma (PTMC). Aggressive surgical treatment with (131)I therapy is indicated for nonincidental PTMC. METHODS:This is a retrospective analysis o...

journal_title：Annals of surgical oncology

authors： Lin JD,Kuo SF,Chao TC,Hsueh C

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:We defined the indications for and evaluated the results of a new technique for radioguided surgery, the SiteSelect system. The procedure allows en-bloc resection of the breast parenchyma under local anesthesia. METHODS:This prospective study was based on 167 patients operated on between December 2000 and O...

journal_title：Annals of surgical oncology

authors： Doridot V,Meunier M,El Khoury C,Nos C,Vincent-Salomon A,Sigal-Zafrani B,Clough KB,Institut Curie Breast Cancer Group.

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Hepatitis B (HBV)-associated hepatocellular carcinoma (HCC) is often associated with alpha-fetoprotein (AFP) production. Although serum AFP has been demonstrated to be a prognostic factor for patient survival, optimal cutoff levels remain unclear. METHODS:Patients with HBV-associated HCC treated by primary ...

journal_title：Annals of surgical oncology

authors： Blank S,Wang Q,Fiel MI,Luan W,Kim KW,Kadri H,Mandeli J,Hiotis SP

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:This study aimed to investigate changes in treatment strategy and outcome for patients with primary retroperitoneal sarcoma (RPS) undergoing resection at referral centers during a recent period. METHODS:The study enrolled consecutive adult patients with primary non-metastatic RPS who underwent resection wit...

journal_title：Annals of surgical oncology

authors： Callegaro D,Raut CP,Ng D,Strauss DC,Honoré C,Stoeckle E,Bonvalot S,Haas RL,Vassos N,Conti L,Gladdy RA,Fairweather M,van Houdt W,Schrage Y,van Coevorden F,Rutkowski P,Miceli R,Gronchi A,Swallow CJ

更新日期：2020-10-18 00:00:00

abstract：BACKGROUND:Metastases to internal mammary lymph nodes (IMN) may occur in patients with breast cancer and may alter treatment recommendations. The purpose of this study was to identify the frequency of IMN drainage in patients undergoing breast lymphoscintigraphy and sentinel lymph node dissection (SLND). METHODS:The c...

journal_title：Annals of surgical oncology

authors： Byrd DR,Dunnwald LK,Mankoff DA,Anderson BO,Moe RE,Yeung RS,Schubert EK,Eary JF

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:The treatment strategy and benefit of extended lymph node dissection among patients with preoperatively diagnosed paraaortic lymph node metastasis (PALNM) in colon cancer remains highly controversial. In the current study, we analyzed the oncologic outcomes of patients who underwent extraregional lymph node ...

journal_title：Annals of surgical oncology

authors： Bae SU,Han YD,Cho MS,Hur H,Min BS,Baik SH,Lee KY,Kim NK

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Cancer patients have often been reported to have impaired immune function, and the effect of treatment modalities, such as surgery, irradiation, and chemotherapy, in depressing patients' immunity has also been reported. In this investigation, the effect of treatment on the cellular immunity of esophageal can...

journal_title：Annals of surgical oncology

authors： Mafune K,Tanaka Y

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Endoscopic resection (ER) is an effective treatment for early gastric cancer (EGC) without lymph node metastasis. However, after ER additional surgery may be needed to manage the risks presented by residual cancer or lymph node metastasis. METHODS:ER was performed on 344 gastric adenocarcinomas between Nove...

journal_title：Annals of surgical oncology

authors： Ryu KW,Choi IJ,Doh YW,Kook MC,Kim CG,Park HJ,Lee JH,Lee JS,Lee JY,Kim YW,Bae JM

更新日期：2007-12-01 00:00:00

abstract：:Investigators at many cancer centers have verified that the sentinel node (SN) is the first lymph node to receive lymphatic drainage from a primary breast cancer and therefore the node most likely to contain metastatic tumor cells. When sentinel lymph node dissection (SLND) is undertaken by an experienced multidiscipl...

journal_title：Annals of surgical oncology

authors： Giuliano AE

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Accumulated evidence indicates that the incidence of early-onset breast cancer has rapidly increased in Taiwan and other Asian compared to Western countries. The mismatch repair (MMR) pathway might be one of the crucial mechanisms of predisposition to early breast cancer. In this study, we explored whether M...

journal_title：Annals of surgical oncology

authors： Hsieh YC,Cho EC,Tu SH,Wu CH,Hung CS,Hsieh MC,Su CT,Liu YR,Lee CH,Ho YS,Chiou HY

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Patients with locally advanced rectal cancer may present with synchronous distant metastases. Choice of optimal treatment--neoadjuvant chemoradiation versus systemic chemotherapy alone--depends on accurate assessment of distant disease. We prospectively evaluated the ability of [18F]fluorodeoxyglucose ([18F]...

journal_title：Annals of surgical oncology

authors： Nahas CS,Akhurst T,Yeung H,Leibold T,Riedel E,Markowitz AJ,Minsky BD,Paty PB,Weiser MR,Temple LK,Wong WD,Larson SM,Guillem JG

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Primary gastrointestinal sarcomas are uncommon, and the clinicopathological determinants of survival remain unclear. In order to correlate clinical presentation, pathological assessment, and treatment with outcome, we have analyzed our institution's recent experience with these tumors. METHODS:Records of ad...

journal_title：Annals of surgical oncology

authors： Conlon KC,Casper ES,Brennan MF

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:The sentinel lymph node (SLN) concept has been gaining attention for gastrointestinal neoplasms but remains controversial for esophageal cancer. This study evaluated the feasibility of SLN identification using intraoperative indocyanine green (ICG) fluorescence imaging (IGFI) navigated by preoperative comput...

journal_title：Annals of surgical oncology

authors： Yuasa Y,Seike J,Yoshida T,Takechi H,Yamai H,Yamamoto Y,Furukita Y,Goto M,Minato T,Nishino T,Inoue S,Fujiwara S,Tangoku A

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Extraskeletal myxoid chondrosarcoma (EMC) is a rare sarcoma of uncertain origin, marked by specific chromosomal translocations involving the NR4A3 gene, and usually characterized by an indolent course. Surgery (with or without radiotherapy) is the treatment of choice in localized disease. The treatment for a...

journal_title：Annals of surgical oncology

authors： Paioli A,Stacchiotti S,Campanacci D,Palmerini E,Frezza AM,Longhi A,Radaelli S,Donati DM,Beltrami G,Bianchi G,Barisella M,Righi A,Benini S,Fiore M,Picci P,Gronchi A

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:L1, a new target gene for Wnt/beta-catenin-TCF signaling, has been identified in the invasive front of colorectal cancer cells in vitro study. The L1 molecule is localized on the cell surface in tumor tissues, accompanied with loss of beta-catenin and E-cadherin. However, such association between L1 expressi...

journal_title：Annals of surgical oncology

authors： Boo YJ,Park JM,Kim J,Chae YS,Min BW,Um JW,Moon HY

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:In recent years, as a result of refinement in molecular biology techniques, significant progress has been made in the understanding of colorectal carcinogenesis. Particular attention has been drawn to identification of genetic mutation that may predispose to colorectal carcinoma (familial syndromes) and may ...

journal_title：Annals of surgical oncology

authors： Pricolo VE,Finkelstein SD,Bland KI

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Understanding the natural progression of untreated gastric cancer is critical for determining the disease prognosis as well as treatment options and timing. The aim of this study is to analyze the natural history of gastric cancer. PATIENTS AND METHODS:We included patients with gastric cancer who had not re...

journal_title：Annals of surgical oncology

authors： Oh SY,Lee JH,Lee HJ,Kim TH,Huh YJ,Ahn HS,Suh YS,Kong SH,Kim GH,Ahn SJ,Kim SH,Choi Y,Yang HK

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Various patient, treatment, and pathologic factors have been associated with an increased risk of local recurrence (LR) following breast-conserving therapy (BCT) for ductal carcinoma in situ (DCIS). However, the strength and importance of individual factors has varied; whether combining factors improves pred...

journal_title：Annals of surgical oncology

authors： Collins LC,Achacoso N,Haque R,Nekhlyudov L,Quesenberry CP Jr,Schnitt SJ,Habel LA,Fletcher SW

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:This study was designed to compare the clinical outcomes of patients who underwent limited resection (LR) versus pancreaticoduodenectomy (PD) for duodenal gastrointestinal stromal tumors (GISTs). METHODS:A systematic review of the literature was performed to identify studies analyzing the clinical outcomes of ...

journal_title：Annals of surgical oncology

authors： Chok AY,Koh YX,Ow MY,Allen JC Jr,Goh BK

更新日期：2014-10-01 00:00:00

abstract：:C.R. Farley and M.C. Perez contributed equally to this publication and are co-first authors. J.S. Zager and M.C. Lowe contributed equally to this publication and are co-corresponding authors. ...

journal_title：Annals of surgical oncology

authors： Farley CR,Perez MC,Soelling SJ,Delman KA,Harit A,Wuthrick EJ,Messina JL,Sondak VK,Zager JS,Lowe MC

更新日期：2020-12-01 00:00:00

abstract：:Multiple randomized trials, as well as a meta-analysis of these studies, have confirmed the equivalence of breast-conservation and mastectomy. In addition, in unselected populations, adjuvant radiation therapy following lumpectomy has been shown to decrease in-breast recurrence and improve overall survival. However, r...

journal_title：Annals of surgical oncology

authors： Bellon JR,Golshan M,Solin LJ

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Initial therapy for early hepatocellular carcinoma (HCC) with well-compensated cirrhosis is controversial. While we previously reported on the effect of clinical factors and surgeon specialty on choice of therapy for early HCC, other nonclinical factors also may impact decision-making. METHODS:Surgeons who ...

journal_title：Annals of surgical oncology

authors： Nathan H,Segev DL,Bridges JF,Massie AB,Cameron AM,Hirose K,Schulick RD,Choti MA,Pawlik TM

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Endoscopic biliary drainage (EBD) and percutaneous transhepatic biliary drainage (PTBD) are both used to resolve jaundice before surgery for perihilar cholangiocarcinoma (PHC). PTBD has been associated with seeding metastases. The aim of this study was to compare overall survival (OS) and the incidence of in...

journal_title：Annals of surgical oncology

authors： Wiggers JK,Groot Koerkamp B,Coelen RJ,Doussot A,van Dieren S,Rauws EA,Schattner MA,van Lienden KP,Brown KT,Besselink MG,van Tienhoven G,Allen PJ,Busch OR,D'Angelica MI,DeMatteo RP,Gouma DJ,Kingham TP,Verheij J,Jarnagi

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Given the emerging evidence supporting the lack of prognostic significance of gross extrathyroidal extension invading only strap muscles (strap-gETE), this study investigated whether lobectomy is feasible for patients with strap-gETE. METHODS:A retrospective cohort study was conducted with 636 patients who ...

journal_title：Annals of surgical oncology

authors： Song E,Kim WW,Jeon MJ,Sung TY,Song DE,Kim TY,Chung KW,Kim WB,Shong YK,Hong SJ,Lee YM,Kim WG

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Metastatic breast cancer is an aggressive disease associated with recurrence and decreased survival. To improve outcomes and develop more effective treatment strategies for patients with breast cancer, it is important to understand the molecular mechanisms underlying metastasis. METHODS:We used allelic imba...

journal_title：Annals of surgical oncology

authors： Becker TE,Ellsworth RE,Deyarmin B,Patney HL,Jordan RM,Hooke JA,Shriver CD,Ellsworth DL

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Contralateral prophylactic mastectomy (CPM) is expected to add surgical morbidity but this incremental risk has not yet been defined. We sought to quantify the additional risks associated with CPM and determine how these risks influence the time to adjuvant therapy. METHODS:We identified women undergoing ma...

journal_title：Annals of surgical oncology

authors： Eck DL,Perdikis G,Rawal B,Bagaria S,McLaughlin SA

更新日期：2014-10-01 00:00:00