Surgical indication for non-curative endoscopic resection in early gastric cancer.

Abstract:

BACKGROUND:Endoscopic resection (ER) is an effective treatment for early gastric cancer (EGC) without lymph node metastasis. However, after ER additional surgery may be needed to manage the risks presented by residual cancer or lymph node metastasis. METHODS:ER was performed on 344 gastric adenocarcinomas between November 2001 and April 2006 at the Korean National Cancer Center under the strict pre-procedural indication. The authors performed operations in 43 patients due to: residual mucosal cancer, a mucosal cancer larger than 3 cm, or a submucosal cancer regardless of size or margin involvement. ER and surgical specimens were reviewed and analyzed for residual cancer and lymph node metastasis. RESULTS:Based on examinations of ER specimens, cancer was confined to the mucosal layer in 15 patients (34.9%) and invaded the submucosal layer in 28 patients (65.1%). Surgical specimens showed residual cancer in 17 patients (39.5%) and lymph node metastasis in four (9.3%). Neither residual cancer nor lymph node metastasis was found in patients with less than 500 microm submucosal invasion without margin involvement in ER specimens. In three of four patients with lymph node metastasis, the depth of submucosal invasion was 500 microm or more; the remaining patient had a 4-cm-sized differentiated mucosal cancer. CONCLUSIONS:When a pathologic evaluation of an ER specimen reveals more than 500 microm of submucosal invasion or a mucosal cancer of larger than 3 cm, surgery should be considered due to the risk of lymph node metastasis.

journal_name

Ann Surg Oncol

authors

Ryu KW,Choi IJ,Doh YW,Kook MC,Kim CG,Park HJ,Lee JH,Lee JS,Lee JY,Kim YW,Bae JM

doi

10.1245/s10434-007-9536-z

subject

Has Abstract

pub_date

2007-12-01 00:00:00

pages

3428-34

issue

12

eissn

1068-9265

issn

1534-4681

journal_volume

14

pub_type

杂志文章
  • Optical See-Through Cancer Vision Goggles Enable Direct Patient Visualization and Real-Time Fluorescence-Guided Oncologic Surgery.

    abstract:BACKGROUND:The inability to visualize the patient and surgical site directly, limits the use of current near infrared fluorescence-guided surgery systems for real-time sentinel lymph node biopsy and tumor margin assessment. METHODS:We evaluated an optical see-through goggle augmented imaging and navigation system (GAI...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-017-5804-8

    authors: Mondal SB,Gao S,Zhu N,Habimana-Griffin L,Akers WJ,Liang R,Gruev V,Margenthaler J,Achilefu S

    更新日期:2017-07-01 00:00:00

  • Influence of Food Intake on the Healing Process of Postoperative Pancreatic Fistula After Pancreatoduodenectomy: A Multi-institutional Randomized Controlled Trial.

    abstract:BACKGROUND:The usefulness of enteral nutrition via a nasointestinal tube for patients who develop postoperative pancreatic fistula (POPF) after miscellaneous pancreatectomy procedures has been reported. However, no clear evidence regarding whether oral intake is possible during management of POPF after pancreatoduodene...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1245/s10434-015-4496-1

    authors: Fujii T,Nakao A,Murotani K,Okamura Y,Ishigure K,Hatsuno T,Sakai M,Yamada S,Kanda M,Sugimoto H,Nomoto S,Takeda S,Morita S,Kodera Y

    更新日期:2015-11-01 00:00:00

  • Effect of Extending the Original CROSS Criteria on Tumor Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer Patients: A National Multicenter Cohort Analysis.

    abstract:BACKGROUND:Extending the original criteria of the Chemoradiotherapy for Oesophageal Cancer followed by Surgery Study (CROSS) in daily practice may increase the treatment outcome of esophageal cancer (EC) patients. This retrospective national cohort study assessed the impact on the pathologic complete response (pCR) rat...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-020-09372-y

    authors: Wang HH,de Heer EC,Hulshoff JB,Kats-Ugurlu G,Burgerhof JGM,van Etten B,Plukker JTM,Hospers GAP,Dutch Upper Gastrointestinal Cancer Audit (DUCA) Group.

    更新日期:2020-11-28 00:00:00

  • Predictive Potential of Preoperative Nutritional Status in Long-Term Outcome Projections for Patients with Gastric Cancer.

    abstract:BACKGROUND:Preoperative nutritional status not only correlates with the incidence of postoperative complications but also may be indicative of long-term outcomes for patients with cancer. The impact of preoperative nutritional status on outcomes for patients undergoing gastrectomy for gastric cancer (GC) was investigat...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-015-4814-7

    authors: Sakurai K,Ohira M,Tamura T,Toyokawa T,Amano R,Kubo N,Tanaka H,Muguruma K,Yashiro M,Maeda K,Hirakawa K

    更新日期:2016-02-01 00:00:00

  • Cytoreductive surgery under aminolevulinic acid-mediated photodynamic diagnosis plus hyperthermic intraperitoneal chemotherapy in patients with peritoneal carcinomatosis from ovarian cancer and primary peritoneal carcinoma: results of a phase I trial.

    abstract:BACKGROUND:We conducted a phase I clinical trial to evaluate the sensitivity, specificity, and safety of cytoreductive surgery (CRS) under aminolevulinic acid-mediated photodynamic diagnosis (ALA-PDD) plus hyperthermic intraperitoneal chemotherapy (HIPEC) on 20 patients with peritoneal carcinomatosis (PC) from ovarian ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-014-3901-5

    authors: Liu Y,Endo Y,Fujita T,Ishibashi H,Nishioka T,Canbay E,Li Y,Ogura S,Yonemura Y

    更新日期:2014-12-01 00:00:00

  • The role of radiation therapy after nipple-sparing mastectomy.

    abstract:PURPOSE:The aim of this review was to examine the incidence of nipple-areola complex (NAC) involvement, the rates of NAC recurrence, and the data regarding the role of radiation therapy (RT) following nipple-sparing mastectomy (NSM). METHODS:A literature review was performed using the PubMed search engine, with articl...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1245/s10434-013-3446-z

    authors: Gomez C,Shah C,McCloskey S,Foster N,Vicini F

    更新日期:2014-07-01 00:00:00

  • The impact of postoperative complications on the administration of adjuvant therapy following pancreaticoduodenectomy for adenocarcinoma.

    abstract:BACKGROUND:The impact of postoperative complications on the administration of adjuvant therapy following pancreaticoduodenectomy (PD) for adenocarcinoma is still unclear. METHODS:A retrospective review of all patients undergoing PD at our institution between 1995 and 2011 was performed. Clinicopathological data, inclu...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-014-3722-6

    authors: Wu W,He J,Cameron JL,Makary M,Soares K,Ahuja N,Rezaee N,Herman J,Zheng L,Laheru D,Choti MA,Hruban RH,Pawlik TM,Wolfgang CL,Weiss MJ

    更新日期:2014-09-01 00:00:00

  • Impact and outcomes of routine microstaging of sentinel lymph nodes in breast cancer: significance of the pN0(i+) and pN1mi categories.

    abstract:BACKGROUND:In 2003, the American Joint Committee on Cancer (AJCC) initiated the 6th edition staging criteria, including pN0(i+) and pN1mi categories for breast cancer. However, the clinical significance of these categories is debated in the literature. METHODS:A prospective registry was used to identify patients stage...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-008-0121-x

    authors: Pugliese MS,Beatty JD,Tickman RJ,Allison KH,Atwood MK,Szymonifka J,Arthurs ZM,Huynh PP,Dawson JH

    更新日期:2009-01-01 00:00:00

  • p53 genotype predicts response to chemotherapy in patients with squamous cell carcinoma of the esophagus.

    abstract:BACKGROUND:Response to chemotherapy and anatomical spread are significant prognostic factors in patients with esophageal squamous cell carcinoma (ESCC) treated by chemotherapy then surgery. Predicting the response to chemotherapy would allow significant optimization of cancer treatment. METHODS:Genomic mutation and pr...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-009-0851-4

    authors: Yamasaki M,Miyata H,Fujiwara Y,Takiguchi S,Nakajima K,Nishida T,Yasuda T,Matsuyama J,Mori M,Doki Y

    更新日期:2010-02-01 00:00:00

  • Sentinel-Lymph-Node-Based Management or Routine Axillary Clearance? Five-Year Outcomes of the RACS Sentinel Node Biopsy Versus Axillary Clearance (SNAC) 1 Trial: Assessment and Incidence of True Lymphedema.

    abstract:PURPOSE:To determine whether the benefits of sentinel-node-based management (SNBM) over routine axillary clearance (RAC) persisted to 5 years. METHODS:A total of 1088 women with breast cancer less than 3 cm in diameter and clinically negative axillary nodes were randomized to SNBM with axillary clearance if the sentin...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,随机对照试验

    doi:10.1245/s10434-016-5669-2

    authors: Wetzig N,Gill PG,Espinoza D,Mister R,Stockler MR,Gebski VJ,Ung OA,Campbell I,Simes J

    更新日期:2017-04-01 00:00:00

  • Tumor-associated macrophages promote oral cancer progression through activation of the Axl signaling pathway.

    abstract:BACKGROUND:Recent studies suggest that tumor-associated macrophages (TAMs) promote tumor growth and metastasis. Our previous report demonstrated that Axl signaling promotes carcinogenesis and progression of oral squamous cell carcinoma (OSCC). This study aims to test the potential involvement of growth arrest-specific ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-013-3400-0

    authors: Lee CH,Liu SY,Chou KC,Yeh CT,Shiah SG,Huang RY,Cheng JC,Yen CY,Shieh YS

    更新日期:2014-03-01 00:00:00

  • Preoperative Pazopanib in High-Risk Soft Tissue Sarcoma: Phase II Window-of Opportunity Study of the German Interdisciplinary Sarcoma Group (NOPASS/GISG-04).

    abstract:BACKGROUND:Preoperative devascularization might improve local control and thus the outcome of patients with soft tissue sarcoma (STS). The multikinase inhibitor pazopanib has antiangiogenic effects and is approved for treating metastatic STS. We conducted a trial of preoperative pazopanib therapy in high-risk STS. MET...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-019-07183-4

    authors: Ronellenfitsch U,Karampinis I,Dimitrakopoulou-Strauss A,Sachpekidis C,Jakob J,Kasper B,Nowak K,Pilz L,Attenberger U,Gaiser T,Derigs HG,Schwarzbach M,Hohenberger P

    更新日期:2019-05-01 00:00:00

  • High serum vascular endothelial growth factor levels predict poor prognosis after radiofrequency ablation of hepatocellular carcinoma: importance of tumor biomarker in ablative therapies.

    abstract:BACKGROUND:Radiofrequency ablation (RFA) is a recently developed treatment for hepatocellular carcinoma (HCC). Thus far, the prognostic impact of tumor biomarkers has not been evaluated in this treatment. High serum level of vascular endothelial growth factor (VEGF) has been shown to predict microscopic vascular invasi...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-007-9366-z

    authors: Poon RT,Lau C,Pang R,Ng KK,Yuen J,Fan ST

    更新日期:2007-06-01 00:00:00

  • Immediate Reconstruction in Inflammatory Breast Cancer: Challenging Current Care.

    abstract:BACKGROUND:Inflammatory breast cancer (IBC) is an aggressive disease that is treated with trimodality therapy consisting of neoadjuvant chemotherapy, surgery, and post-mastectomy radiation therapy (PMRT). Traditionally, modified radical mastectomy without reconstruction has been the operation of choice for patients wit...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-016-5554-z

    authors: Simpson AB,McCray D,Wengler C,Crowe JP,Djohan R,Tendulkar R,O'Rourke C,Grobmyer SR,Valente SA

    更新日期:2016-12-01 00:00:00

  • Breast cancer survival according to number of nodes removed.

    abstract:BACKGROUND:Results from randomized trials indicate a 5.4% survival advantage associated with axillary dissection. To gain insight on survival outcomes when less than an axillary dissection is performed, we performed a retrospective analysis to determine survival outcome for node-negative and node-positive breast cancer...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/aso.2003.03.073

    authors: Krag DN,Single RM

    更新日期:2003-12-01 00:00:00

  • Nephrectomy during operative management of retroperitoneal sarcoma.

    abstract:BACKGROUND:Complete resection of a retroperitoneal sarcoma often requires removal of adjacent organs. In this study we evaluated the role of nephrectomy during operation for retroperitoneal sarcoma. METHODS:Between July 1982 and July 1995, 75 of the 371 (20%) patients who underwent resection of retroperitoneal sarcoma...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1007/BF02305556

    authors: Russo P,Kim Y,Ravindran S,Huang W,Brennan MF

    更新日期:1997-07-01 00:00:00

  • Microscopic Venous Invasion in Pancreatic Cancer.

    abstract:BACKGROUND:Microscopic venous invasion (MVI) and the subsequent peripheral blood circulation of cancer cells are considered to be the primary route for systemic dissemination of pancreatic cancer. METHODS:Patients who underwent pancreatectomy for invasive ductal carcinoma of the pancreas between January 2007 and Decem...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-017-6324-2

    authors: Yamada M,Sugiura T,Okamura Y,Ito T,Yamamoto Y,Ashida R,Sasaki K,Nagino M,Uesaka K

    更新日期:2018-04-01 00:00:00

  • Annexin II overexpression predicts rapid recurrence after surgery in pancreatic cancer patients undergoing gemcitabine-adjuvant chemotherapy.

    abstract:BACKGROUND:Gemcitabine has been shown to exhibit significant clinical activity against pancreatic cancer and has become a first-line chemotherapeutic for this disease in recent years. However, there are still many patients who do not respond to this treatment and it is expected to improve the clinical outcome if we can...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-008-0061-5

    authors: Takano S,Togawa A,Yoshitomi H,Shida T,Kimura F,Shimizu H,Yoshidome H,Ohtsuka M,Kato A,Tomonaga T,Nomura F,Miyazaki M

    更新日期:2008-11-01 00:00:00

  • Does increased experience with isolated limb infusion for advanced limb melanoma influence outcome? A comparison of two treatment periods at a single institution.

    abstract:BACKGROUND:Isolated limb infusion (ILI) with cytotoxic drugs has been used since 1992 to treat advanced melanoma confined to a limb. Over this time the technique has undergone progressive modification. In this study we evaluated our experience with ILI by analyzing outcome and toxicity from an "early" and a "late" trea...

    journal_title:Annals of surgical oncology

    pub_type: 临床试验,杂志文章

    doi:10.1245/s10434-011-1646-y

    authors: Huismans AM,Kroon HM,Kam PC,Thompson JF

    更新日期:2011-07-01 00:00:00

  • Population-Based Study on Risk Factors for Tumor-Positive Resection Margins in Patients with Gastric Cancer.

    abstract:BACKGROUND:Radical gastrectomy is the cornerstone of the treatment of locally advanced gastric cancer. This study was designed to evaluate factors associated with a tumor-positive resection margin after gastrectomy and to evaluate the influence of hospital volume. METHODS:In this Dutch cohort study, patients with junc...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-019-07381-0

    authors: van der Werf LR,Cords C,Arntz I,Belt EJT,Cherepanin IM,Coene PLO,van der Harst E,Heisterkamp J,Langenhoff BS,Lamme B,van Berge Henegouwen MI,Lagarde SM,Wijnhoven BPL

    更新日期:2019-07-01 00:00:00

  • The role of thyroidectomy in metastatic disease to the thyroid gland.

    abstract:BACKGROUND:Whether thyroidectomy for metastases to the thyroid is associated with a survival benefit remains debatable; in general, palliation and disease control are accepted goals in this setting. We evaluated the clinical features and overall survival of patients with thyroid metastasis treated by thyroid resection ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-013-3282-1

    authors: Romero Arenas MA,Ryu H,Lee S,Morris LF,Grubbs EG,Lee JE,Perrier ND

    更新日期:2014-02-01 00:00:00

  • The prognostic significance of nonsentinel lymph node metastasis in melanoma.

    abstract:BACKGROUND:We hypothesized that metastasis beyond the sentinel lymph nodes (SLN) to the nonsentinel nodes (NSN) is an important predictor of survival. MATERIALS AND METHODS:Analysis was performed of a prospective multi-institutional study that included patients with melanoma ≥ 1.0 mm in Breslow thickness. All patients...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1245/s10434-010-1208-8

    authors: Brown RE,Ross MI,Edwards MJ,Noyes RD,Reintgen DS,Hagendoorn LJ,Stromberg AJ,Martin RC,McMasters KM,Scoggins CR

    更新日期:2010-12-01 00:00:00

  • A Population-Based Analysis of Three Treatment Modalities for Malignant Obstruction of the Proximal Colon: Acute Resection Versus Stent or Stoma as a Bridge to Surgery.

    abstract:BACKGROUND:Malignant obstruction of the proximal colon (MOPC) traditionally has been treated with acute resection. However, morbidity and mortality rates following these emergency surgeries are high. Initial bowel decompression by stent placement or stoma construction has been used for distal obstructions as an alterna...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-016-5247-7

    authors: Amelung FJ,Consten ECJ,Siersema PD,Tanis PJ

    更新日期:2016-10-01 00:00:00

  • Intraperitoneal Administration of Paclitaxel Combined with S-1 Plus Oxaliplatin as Induction Therapy for Patients with Advanced Gastric Cancer with Peritoneal Metastases.

    abstract:BACKGROUND:Intraperitoneal (IP) administration of paclitaxel (PTX) has a great pharmacokinetic advantage to control peritoneal lesions and can be combined with various systemic chemotherapies. In this study, we evaluate the efficacy and tolerability of a combination of IP-PTX and systemic S-1/oxaliplatin (SOX) for indu...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-020-09388-4

    authors: Saito S,Yamaguchi H,Ohzawa H,Miyato H,Kanamaru R,Kurashina K,Hosoya Y,Lefor AK,Sata N,Kitayama J

    更新日期:2020-12-03 00:00:00

  • Hiatal Hernia After Open versus Minimally Invasive Esophagectomy: A Systematic Review and Meta-analysis.

    abstract::Hiatal hernia (HH) is an infrequent yet potentially life-threatening complication after esophagectomy. Several studies have reported the incidence of this complication after both open and minimally invasive esophagectomy (MIE). This meta-analysis aimed to determine the pooled incidence of HH after both types of esopha...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1245/s10434-016-5155-x

    authors: Oor JE,Wiezer MJ,Hazebroek EJ

    更新日期:2016-08-01 00:00:00

  • Immediate breast reconstruction for stage III breast cancer using transverse rectus abdominis musculocutaneous (TRAM) flap.

    abstract:BACKGROUND:The management of state III breast cancer is challenging; it often includes multimodal treatment with systemic therapy and/or radiation therapy and surgery. Immediate breast reconstruction has not traditionally been performed in these patients. We review the results of immediate transverse rectus abdominis m...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1007/BF02305667

    authors: Styblo TM,Lewis MM,Carlson GW,Murray DR,Wood WC,Lawson D,Landry J,Hughes L,Nahai F,Bostwick J 3rd

    更新日期:1996-07-01 00:00:00

  • Pediatric and adolescent synovial sarcoma: multivariate analysis of prognostic factors and survival outcomes.

    abstract:PURPOSE:Treatment of synovial sarcoma (SS) is challenging because of its unpredictable clinical behavior. We reviewed our institutional experience with pediatric SS to identify prognostic indicators and survival outcomes. METHODS:We retrospectively reviewed all pediatric/adolescent patients (age<22 years) with confirm...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-012-2587-9

    authors: Stanelle EJ,Christison-Lagay ER,Healey JH,Singer S,Meyers PA,La Quaglia MP

    更新日期:2013-01-01 00:00:00

  • Toxicity of oxaliplatin plus fluorouracil/leucovorin adjuvant chemotherapy in elderly patients with stage III colon cancer: a population-based study.

    abstract:BACKGROUND:Results concerning the side effects of oxaliplatin associated with fluorouracil and leucovorin (FOLFOX) in older patients are controversial. The objective of this study was to assess the use and the toxicity of FOLFOX in patients aged 70 years and older as administered in current practice. METHODS:Among 305...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-013-3438-z

    authors: Hamza S,Bouvier AM,Rollot F,Lepage C,Faivre J,Bedenne L

    更新日期:2014-08-01 00:00:00

  • Improving breast diagnostic services with a Rapid Access Diagnostic and Support (RADS) program.

    abstract:BACKGROUND:The diagnostic phase of care is an anxiety-provoking and stressful experience for the potential breast cancer patient. A multidisciplinary team of breast cancer specialists embarked on a new initiative to pilot a Rapid Diagnosis and Support (RADS) Clinic to coordinate the diagnostic workup and nursing suppor...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-013-3120-5

    authors: Arnaout A,Smylie J,Seely J,Robertson S,Knight K,Shin S,Ramsey T,Mallick R,Watters J

    更新日期:2013-10-01 00:00:00

  • Intraoperative frozen section analysis of sentinel lymph node in breast cancer patients treated with neoadjuvant chemotherapy.

    abstract:BACKGROUND:Recently, many studies have demonstrated the feasibility and accuracy of sentinel lymph node (SLN) biopsy for patients treated with neoadjuvant chemotherapy (NAC). However, no studies have been conducted to evaluate the accuracy of frozen section (FS) analysis of SLN in NAC-treated patients. The aim was to e...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-008-9831-3

    authors: Shimazu K,Tamaki Y,Taguchi T,Tsukamoto F,Kasugai T,Noguchi S

    更新日期:2008-06-01 00:00:00