Toxicity of oxaliplatin plus fluorouracil/leucovorin adjuvant chemotherapy in elderly patients with stage III colon cancer: a population-based study.

abstract：BACKGROUND:Notch1 regulates cell proliferation, development, and apoptosis. Aberrant expression of Notch1 has been discovered in many types of tumors. We examined Notch1 expression in colorectal cancer to assess its role as a prognostic indicator. METHODS:Notch1 protein expression was examined by immunohistochemistry ...

journal_title：Annals of surgical oncology

authors： Chu D,Li Y,Wang W,Zhao Q,Li J,Lu Y,Li M,Dong G,Zhang H,Xie H,Ji G

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has improved the survival in selected colorectal cancer patients with peritoneal metastases. In these patients, the risk of a low anastomosis is sometimes diminished through the creation of a colostomy. Currently, the morbidity...

journal_title：Annals of surgical oncology

authors： de Cuba EM,Verwaal VJ,de Hingh IH,van Mens LJ,Nienhuijs SW,Aalbers AG,Bonjer HJ,te Velde EA

更新日期：2014-03-01 00:00:00

abstract：:The Chicago Consensus Working Group provides multidisciplinary recommendations for the management of colorectal cancer specifically as it relates to the management of peritoneal surface malignancy. These guidelines are developed with input from leading experts including surgical oncologists, medical oncologists, patho...

journal_title：Annals of surgical oncology

authors： Chicago Consensus Working Group.

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Intraperitoneal (IP) administration of paclitaxel (PTX) has a great pharmacokinetic advantage to control peritoneal lesions and can be combined with various systemic chemotherapies. In this study, we evaluate the efficacy and tolerability of a combination of IP-PTX and systemic S-1/oxaliplatin (SOX) for indu...

journal_title：Annals of surgical oncology

authors： Saito S,Yamaguchi H,Ohzawa H,Miyato H,Kanamaru R,Kurashina K,Hosoya Y,Lefor AK,Sata N,Kitayama J

更新日期：2020-12-03 00:00:00

abstract：BACKGROUND:Our objective was to correlate the extent of margin positivity and the findings on re-excision specimens of infiltrating mammary carcinoma. METHODS:We selected 50 consecutive cases of infiltrating mammary carcinoma, including both infiltrating ductal carcinoma and infiltrating lobular carcinoma, with positi...

journal_title：Annals of surgical oncology

authors： Darvishian F,Hajdu SI,DeRisi DC

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Response to neoadjuvant chemotherapy is an independent prognostic factor in locally advanced gastric cancer. However, no prospectively tested pretherapeutic parameters predicting response and/or survival in gastric cancer are available in clinical routine. METHODS:We evaluated the prognostic significance of...

journal_title：Annals of surgical oncology

authors： Lorenzen S,Blank S,Lordick F,Siewert JR,Ott K

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:The benefit of completion lymph node dissection (CLND) in melanoma patients with a positive sentinel lymph node (SLN) remains unknown. METHODS:We identified patients with a positive SLN from 1994 to 2012. Patient and tumor characteristics, reasons for not undergoing CLND, patterns of recurrence, and melanom...

journal_title：Annals of surgical oncology

authors： Bamboat ZM,Konstantinidis IT,Kuk D,Ariyan CE,Brady MS,Coit DG

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:The sentinel lymph node (SLN) is the first lymph node in the regional nodal basin to receive metastatic cells. In-transit nodes are found between the primary melanoma site and regional nodal basins. To date, this is one of the first reports on micrometastasis to in-transit nodes. METHODS:Retrospective datab...

journal_title：Annals of surgical oncology

authors： Thelmo MC,Morita ET,Treseler PA,Nguyen LH,Allen RE Jr,Sagebiel RW,Kashani-Sabet M,Leong SP

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:The appropriate management of breast cancer risk in BRCA mutation carriers following ovarian cancer diagnosis remains unclear. We sought to determine the survival benefit and cost effectiveness of risk-reducing mastectomy (RRM) among women with BRCA1/2 mutations following stage II-IV ovarian cancer. DESIGN:...

journal_title：Annals of surgical oncology

authors： Gamble C,Havrilesky LJ,Myers ER,Chino JP,Hollenbeck S,Plichta JK,Kelly Marcom P,Shelley Hwang E,Kauff ND,Greenup RA

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Dendritic cells (DC) are potent professional antigen-presenting cells that can activate naive T lymphocytes and initiate cellular immune responses. As adjuvants, DC may be useful for enhancing immunogenicity and mediating tumor regression. Endogenous expression of antigen by DC could offer the potential adva...

journal_title：Annals of surgical oncology

authors： Kim CJ,Cormier J,Roden M,Gritz L,Mazzara GP,Fetsch P,Hijazi Y,Lee KH,Rosenberg SA,Marincola FM

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Studies examining differences in presentation of patients with benign [follicular adenoma (FA)] and malignant follicular thyroid neoplasms [follicular thyroid carcinoma (FTC) or follicular variant papillary thyroid carcinoma (FVPTC)] include only one or two of these subtypes, and none has considered clinical...

journal_title：Annals of surgical oncology

authors： Najafian A,Olson MT,Schneider EB,Zeiger MA

更新日期：2015-09-01 00:00:00

abstract：:Selected patients with hepatocellular carcinoma are candidates to receive potentially curative treatments, such as hepatic resection or liver transplantation, but nevertheless there is a high risk of tumor recurrence. Microvascular invasion is a histological feature of hepatocellular carcinoma related to aggressive bi...

journal_title：Annals of surgical oncology

authors： Rodríguez-Perálvarez M,Luong TV,Andreana L,Meyer T,Dhillon AP,Burroughs AK

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Breast reconstruction following mastectomy has been shown to have a salutary effect on the overall psychological well-being of women being treated for breast cancer. Unfortunately, however, not every patient is an ideal candidate for reconstruction. Complications stemming from reconstructive surgery can caus...

journal_title：Annals of surgical oncology

authors： Lin KY,Johns FR,Gibson J,Long M,Drake DB,Moore MM

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Percutaneous ablative therapies (PAT) are valuable modalities for posthepatectomy recurrent hepatocellular carcinoma (RHCC), but its impact on long-term outcome and prognosis prediction have not been well documented. The present study aimed to analyze prognostic factors and to propose a prognosis-predicting ...

journal_title：Annals of surgical oncology

authors： Yin XY,Xie XY,Lu MD,Kuang M,Liu GJ,Xu ZF,Xu HX,Wang Z

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Unlike other human tumors, gastric cancer remains a great therapeutic challenge since no standardized postoperative treatment exists. Knowledge of molecular pathways determining the behavior of individual gastric tumors seems to be crucial for therapeutic decisions, and evaluation of vascular endothelial gro...

journal_title：Annals of surgical oncology

authors： Lieto E,Ferraraccio F,Orditura M,Castellano P,Mura AL,Pinto M,Zamboli A,De Vita F,Galizia G

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Seroma is a frequent problem after mastectomy (ME) and axillary lymph node dissection (ALND). Seroma is associated with pain, discomfort, impaired mobilisation and repeated aspirations, often resulting in a surgical site infection (SSI). It has already been demonstrated that minimizing dead space through fix...

journal_title：Annals of surgical oncology

authors： ten Wolde B,van den Wildenberg FJ,Keemers-Gels ME,Polat F,Strobbe LJ

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Sentinel node biopsy (SNB) may represent an alternative to elective neck dissection for the staging of patients with early head and neck squamous cell carcinoma (HNSCC). To date, the technique has been successfully described in a number of small single-institution studies. This report describes the long-term...

journal_title：Annals of surgical oncology

authors： Alkureishi LW,Ross GL,Shoaib T,Soutar DS,Robertson AG,Thompson R,Hunter KD,Sorensen JA,Thomsen J,Krogdahl A,Alvarez J,Barbier L,Santamaria J,Poli T,Sesenna E,Kovács AF,Grünwald F,Barzan L,Sulfaro S,Alberti F

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Multidisciplinary treatment of rectal cancer, including neoadjuvant treatment, total mesorectal excision, and adjuvant chemotherapy, have improved oncological outcome. Preoperative radiation therapy is advocated by national and international guidelines in all patients with AJCC stage II and III rectal cancer...

journal_title：Annals of surgical oncology

authors： Franz C,Lang HM,Ghamarnejad O,Khajeh E,Mehrabi A,Ulrich A,Schneider M,Büchler MW,Kulu Y

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Malignant ascites (MA) is a distressing problem usually managed by repeated paracenteses. Paracentesis represents a meaningful time point in identifying patients with a specific presentation. OBJECTIVE:The objective of this study is to examine symptom clustering in MA patients at paracentesis. METHODS:Pre-...

journal_title：Annals of surgical oncology

authors： Husain A,Bezjak A,Easson A

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Dickkopf-1 (DKK1) is the inhibitor of the canonical Wnt signaling pathway, however it is highly transactivated in various cancers, suggesting the presence of unknown mechanism. Its implication in human esophageal squamous cell carcinoma (ESCC) has not been sufficiently investigated. PATIENTS ...

journal_title：Annals of surgical oncology

authors： Makino T,Yamasaki M,Takemasa I,Takeno A,Nakamura Y,Miyata H,Takiguchi S,Fujiwara Y,Matsuura N,Mori M,Doki Y

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:COX inhibitors and beta-blockers were recently suggested to reduce cancer progression through inhibition of tumor proliferation and growth factor secretion, induction of tumor apoptosis, and prevention of cellular immune suppression during the critical perioperative period. Here we evaluated the perioperativ...

journal_title：Annals of surgical oncology

authors： Benish M,Bartal I,Goldfarb Y,Levi B,Avraham R,Raz A,Ben-Eliyahu S

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Isolated limb infusion (ILI) is a limb-preserving treatment for in-transit extremity melanoma. The benefit of resecting residual disease after ILI is unclear. METHODS:A multi-institutional experience was analyzed comparing patients who underwent ILI plus resection of residual disease (ILI + RES) versus ILI-...

journal_title：Annals of surgical oncology

authors： Wong J,Chen YA,Fisher KJ,Beasley GM,Tyler DS,Zager JS

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Thirty-day mortality after surgery for colorectal cancer may vastly underestimate 1-year mortality. This study aimed to quantify the excess mortality in the first postoperative year of stage I-III colorectal cancer patients and to identify risk factors for excess mortality. METHODS:All 2,131 patients who we...

journal_title：Annals of surgical oncology

authors： Gooiker GA,Dekker JW,Bastiaannet E,van der Geest LG,Merkus JW,van de Velde CJ,Tollenaar RA,Liefers GJ

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Melanoma metastatic to the gastrointestinal (GI) tract is asymptomatic or presents with pain, bleeding, or obstruction. To determine whether surgery influences outcomes, we reviewed our experience with this patient population. METHODS:Medical records of patients with metastatic melanoma to the GI tract were...

journal_title：Annals of surgical oncology

authors： Berger AC,Buell JF,Venzon D,Baker AR,Libutti SK

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Breast surgery has evolved with more focus on improving cosmetic outcomes, which requires increased operative time and technical complexity. Implications of these technical advances in surgery for the surgeon are unclear, but they may increase intraoperative demands, both mentally and physically. We prospect...

journal_title：Annals of surgical oncology

authors： Hallbeck MS,Law KE,Lowndes BR,Linden AR,Morrow M,Blocker RC,Cain SM,Degnim AC,Hieken TJ,Jakub JW,Racz JM,Farley DR,Nelson H,Boughey JC

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Vitamin B12 deficiency is a common long-term sequelae after total gastrectomy. Intramuscular injection of vitamin B12 is the only known treatment. We investigated the efficacy and safety of oral vitamin B12 replacement for gastric cancer patients with vitamin B12 deficiency after total gastrectomy. METHODS:...

journal_title：Annals of surgical oncology

authors： Kim HI,Hyung WJ,Song KJ,Choi SH,Kim CB,Noh SH

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:The keystone flap is being promoted as an advance in oncological surgical reconstruction. Wound closure with this island flap involves two V-Y advancements toward the center and along the long axis of the island, at right angles to the line of maximum tension when the wound is closed. It is implied that the ...

journal_title：Annals of surgical oncology

authors： Douglas CD,Low NC,Seitz MJ

更新日期：2013-03-01 00:00:00

abstract：: ...

journal_title：Annals of surgical oncology

authors： Blok RD,Tanis PJ

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The prognosis of biliary tract cancer (BTC) is unfavorable due to its chemoresistance. Hypoxia triggers epithelial-to-mesenchymal transition (EMT), which is closely related to drug resistance. In this study, we focused on the functional roles of procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2), a h...

journal_title：Annals of surgical oncology

authors： Okumura Y,Noda T,Eguchi H,Sakamoto T,Iwagami Y,Yamada D,Asaoka T,Wada H,Kawamoto K,Gotoh K,Kobayashi S,Takeda Y,Tanemura M,Umeshita K,Doki Y,Mori M

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Gastrointestinal leak (GIL) after cytoreductive surgery with heated intraperitoneal chemotherapy (CRS/HIPEC) is associated with significant morbidity and mortality. This study aimed to identify GIL prognostic factors and its impact on overall survival. METHODS:A retrospective analysis of a prospectively mai...

journal_title：Annals of surgical oncology

authors： Chouliaras K,Levine EA,Fino N,Shen P,Votanopoulos KI

更新日期：2017-04-01 00:00:00