Tumor-associated macrophages promote oral cancer progression through activation of the Axl signaling pathway.

abstract：BACKGROUND:Although an age cutoff of 45 years has often been adopted to stratify cancer risk in papillary thyroid carcinoma (PTC), both cancer-specific survival (CSS) and disease-specific survival (DFS) continue to worsen beyond this cutoff. This study aimed to determine whether advanced age (i.e., >60 years) at diagno...

journal_title：Annals of surgical oncology

authors： Lang BH,Lo CY,Wong KP,Wan KY

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Epigenetic silencing of tumor-related genes by CpG island methylation is an important mechanism for the development of many tumors, including gastric carcinoma. Deregulation of transcription factor 4 (TCF4) by promoter methylation was recently shown to play a key role in gastric carcinogenesis. METHODS:The ...

journal_title：Annals of surgical oncology

authors： Joo JK,Kim SH,Kim HG,Kim DY,Ryu SY,Lee KH,Lee JH

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:The association between procedure volume and clinical outcomes has led many to advocate centralization of cancer procedures at high-volume centers (HVCs). Regional studies show practice patterns changing with increasing centralization of esophageal and pancreatic procedures at HVCs but little change for colo...

journal_title：Annals of surgical oncology

authors： Stitzenberg KB,Meropol NJ

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Current nodal staging (N-staging) of ampullary carcinoma in the TNM staging system distinguishes between node-negative (N0) and node-positive (N1) disease but does not consider the metastatic lymph node (LN) number. METHODS:Overall, 313 patients who underwent pancreatoduodenectomy for ampullary adenocarcino...

journal_title：Annals of surgical oncology

authors： Balci S,Basturk O,Saka B,Bagci P,Postlewait LM,Tajiri T,Jang KT,Ohike N,Kim GE,Krasinskas A,Choi H,Sarmiento JM,Kooby DA,El-Rayes BF,Knight JH,Goodman M,Akkas G,Reid MD,Maithel SK,Adsay V

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinase 7 (MMP-7) is involved in invasion, metastasis, growth, and angiogenesis. The aim of this study is to assess the prognostic role of serum MMP-7 in curatively resected colorectal cancer (CRC). MATERIALS AND METHODS:Patients undergoing resection for CRC (n = 175) were recruited from Ju...

journal_title：Annals of surgical oncology

authors： Martínez-Fernandez A,García-Albeniz X,Pineda E,Visa L,Gallego R,Codony-Servat J,Augé JM,Longarón R,Gascón P,Lacy A,Castells A,Maurel J

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:The primary objective of this study was to determine the true proportion and optimal surgical approach for individuals undergoing thyroid operation for a suspicion of cancer based on a fine-needle aspiration biopsy diagnosis of a follicular neoplasm (FN). A secondary objective of this study was to determine ...

journal_title：Annals of surgical oncology

authors： Wiseman SM,Baliski C,Irvine R,Anderson D,Wilkins G,Filipenko D,Zhang H,Bugis S

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:There is increasing evidence that tumor hypoxia plays a significant role in the chemoresistance of melanoma, but to our knowledge, real-time tumor oxygenation during isolated limb infusion (ILI) has not been studied. We sought to demonstrate the feasibility of measuring real-time alterations in tissue oxygen...

journal_title：Annals of surgical oncology

authors： Speicher PJ,Beasley GM,Jiang B,Lidsky ME,Palmer GM,Scarbrough PM,Mosca PJ,Dewhirst MW,Tyler DS

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Survival for Child's A patients with hepatocellular cancer (HCC) and macroscopic vascular invasion (MVI) has been reported as approximately 8.1 months with sorafenib. The role of surgery for these patients remains controversial. METHODS:The records of all patients undergoing resection of HCC at a single cen...

journal_title：Annals of surgical oncology

authors： Roayaie S,Jibara G,Taouli B,Schwartz M

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Surgical resection of the primary tumor for patients who present with incurable stage IV colorectal cancer is controversial. National practice patterns have not been described. We evaluated the use of primary tumor resection in patients presenting with stage IV colorectal cancer. METHODS:Patients with stage...

journal_title：Annals of surgical oncology

authors： Cook AD,Single R,McCahill LE

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:The heterogeneous nuclear ribonucleoprotein (hnRNP) K is an essential RNA and DNA binding protein involved in gene expression and signal transduction. The role of hnRNP K in cancer is relatively understudied. However, several cellular functions strongly indicate that hnRNP K is involved in tumorigenesis. Onc...

journal_title：Annals of surgical oncology

authors： Wen F,Shen A,Shanas R,Bhattacharyya A,Lian F,Hostetter G,Shi J

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:The rarity of melanoma in young patients, particularly pediatric ones, has to date precluded any valid comparisons being made between young patients and adults undergoing sentinel lymph node biopsy (SLNB) for intermediate thickness localized melanoma. The present study takes advantage of the large Sydney Mel...

journal_title：Annals of surgical oncology

authors： Howman-Giles R,Shaw HM,Scolyer RA,Murali R,Wilmott J,McCarthy SW,Uren RF,Thompson JF

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Ductal carcinoma in situ with microinvasion (DCISM) is a rare diagnosis with a good prognosis. Although nodal metastases are uncommon, sentinel lymph node biopsy (SLNB) remains standard care. Volume of disease in invasive breast cancer is associated with SLNB positivity, and, thus we hypothesized that in a l...

journal_title：Annals of surgical oncology

authors： Matsen CB,Hirsch A,Eaton A,Stempel M,Heerdt A,Van Zee KJ,Cody HS 3rd,Morrow M,Plitas G

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The 5th edition of Breast Imaging Reporting and Data System subdivides suspicious calcifications into two categories: 4B-amorphous, coarse heterogeneous, and fine pleomorphic calcifications; 4C-fine linear or fine linear branching calcifications. We investigated whether these revised categories are appropria...

journal_title：Annals of surgical oncology

authors： Kim SY,Kim HY,Kim EK,Kim MJ,Moon HJ,Yoon JH

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:This study was designed to investigate the correlation between postoperative recurrence of hepatocellular carcinoma (HCC) and perioperative expression and dynamic changes in cancer stem cell (CSC) markers in tumors and peripheral blood. METHODS:In HCC patients who underwent curative resection (n = 64) or li...

journal_title：Annals of surgical oncology

authors： Choi GH,Kim GI,Yoo JE,Na DC,Han DH,Roh YH,Park YN,Choi JS

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel approach to delivering intraperitoneal chemotherapy (IPC) as a pressurized aerosol. One of the assumed advantages is the homogeneous drug distribution in the intraperitoneal cavity compared with conventional liquid in situ chemotherapy. Howe...

journal_title：Annals of surgical oncology

authors： Khosrawipour V,Khosrawipour T,Diaz-Carballo D,Förster E,Zieren J,Giger-Pabst U

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Local recurrence occurs in 10% to 20% of patients with extremity soft tissue sarcomas despite optimal treatment. The association of local recurrence with subsequent survival is controversial and conflicting. There is a need for a staging system to predict outcome in this subset of patients and also to plan o...

journal_title：Annals of surgical oncology

authors： Ramanathan RC,A'Hern R,Fisher C,Thomas JM

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Preliminary data indicate that tyrosine kinase inhibitors (TKIs) function through rearranged during transfection (RET) in breast cancer. However, TKIs are not specific and can block several receptor tyrosine kinases (RTKs). This study used cell lines and primary breast cancer specimens to determine factors a...

journal_title：Annals of surgical oncology

authors： Spanheimer PM,Lorenzen AW,De Andrade JP,Kulak MV,Carr JC,Woodfield GW,Sugg SL,Weigel RJ

更新日期：2015-12-01 00:00:00

abstract：:The surveillance of breast cancer patients after potentially curative treatment may result in the identification of locoregional or distant recurrence. While many patients expect frequent imaging studies to monitor for recurrence, there are no data supporting aggressive imaging surveillance beyond mammography. However...

journal_title：Annals of surgical oncology

authors： Leitch AM

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Neoadjuvant chemoradiation followed by surgery and adjuvant chemotherapy is typically recommended for patients with locally advanced rectal cancer. Patients with pathologically node-negative tumors have an improved prognosis, but recurrence patterns and independent prognostic factors in these patients have b...

journal_title：Annals of surgical oncology

authors： Govindarajan A,Reidy D,Weiser MR,Paty PB,Temple LK,Guillem JG,Saltz LB,Wong WD,Nash GM

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Reduced port laparoscopic surgery (RPLS), as a more minimally invasive treatment alternative to conventional laparoscopic surgery (CLS), has been increasing in recent years. 1 With the accumulation of surgical experience and improvements in surgical techniques, the indication of RPLS has been gradually exten...

journal_title：Annals of surgical oncology

authors： Lin T,Mou TY,Hu YF,Liu H,Li TJ,Lu YM,Yu J,Li GX

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Although significant progress has been made in the management of children with Wilms tumor, two major controversies still exist: the extent of radiographic evaluation necessary before surgery and the role of preoperative chemotherapy. This study sought to determine whether patients with Wilms tumor who prese...

journal_title：Annals of surgical oncology

authors： Davidoff AM,Soutter AD,Shochat SJ

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:The use of immunotherapeutic agents, specifically immune checkpoint inhibitors (ICIs) for solid malignancies, is rapidly rising, and many new agents and treatment combinations are in development. However, ICIs have a unique side-effect profile of immune-related adverse events (irAEs) compared with chemothera...

journal_title：Annals of surgical oncology

authors： Helmink BA,Roland CL,Kiernan CM,Wargo JA

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Pathologic complete response (pCR) of rectal cancer following neoadjuvant therapy is associated with decreased local recurrence and increased overall survival. This study utilizes a national dataset to identify predictors of pCR in patients with rectal cancer. METHODS:The National Cancer Database was querie...

journal_title：Annals of surgical oncology

authors： Lorimer PD,Motz BM,Kirks RC,Boselli DM,Walsh KK,Prabhu RS,Hill JS,Salo JC

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:Recently, the American Joint Committee on Cancer (AJCC) 7th edition proposed new response criteria for neoadjuvant chemotherapy (NAC) in breast cancer. The purpose of this study was to evaluate the clinical usefulness of AJCC response criteria. METHODS:A total of 398 consecutive stage II or III breast cancer p...

journal_title：Annals of surgical oncology

authors： Keam B,Im SA,Lim Y,Han SW,Moon HG,Oh DY,Cho N,Lee SH,Han W,Moon WK,Kim DW,Kim TY,Park IA,Noh DY

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:To determine the effect of flap reconstruction on perineal complications in locally advanced rectal cancers (LARC) and locally recurrent rectal cancers (LRRC). Prior studies have suggested that flap reconstruction may decrease wound complications after ablative surgery for rectal cancer but are limited by sm...

journal_title：Annals of surgical oncology

authors： Davidge KM,Raghuram K,Hofer SO,Ferguson PC,Wunder JS,Swallow CJ,Zhong T

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Accurate prediction of treatment response and prognosis before surgery allows prompt therapy adjustment. This study aimed to evaluate the efficacy of computed tomography (CT) signs in predicting treatment response and survival for advanced esophageal squamous cell carcinoma patients who received preoperative...

journal_title：Annals of surgical oncology

authors： Zhang XY,Yan WP,Sun Y,Li XT,Chen Y,Fan MY,Wu Y,Liang Z,Xiong HC,Wang ZL,Sun YS,Chen KN

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Neoadjuvant endocrine therapy (NET) is effective in downstaging large hormone receptor-positive (HR+) breast cancers and increasing rates of breast-conserving surgery (BCS), but data regarding nodal pathologic complete response (pCR) are sparse. We reported nodal and breast downstaging rates with NET, and co...

journal_title：Annals of surgical oncology

authors： Montagna G,Sevilimedu V,Fornier M,Jhaveri K,Morrow M,Pilewskie ML

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Reactive oxygen species (free radicals) play an important role in carcinogenesis. Extensive antioxidant defense mechanisms counteract free radicals in mammalian cells. Oxidative stress is a disturbance in the balance between the production of free radicals and antioxidant defenses. There is direct evidence t...

journal_title：Annals of surgical oncology

authors： Kilic N,Yavuz Taslipinar M,Guney Y,Tekin E,Onuk E

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Heated intraoperative intraperitoneal chemotherapy achieves high peritoneal concentrations with limited systemic absorption and has become an important tool in the management of patients with peritoneal carcinomatosis from low-grade malignancies such as pseudomyxoma peritonei and in selected cases of high-gr...

journal_title：Annals of surgical oncology

authors： Esquivel J,Angulo F,Bland RK,Stephens AD,Sugarbaker PH

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:To improve the poor prognosis of patients with advanced incurable gastric cancer, intensive chemotherapy combined with radical surgery was used. PATIENTS AND METHODS:Thirty patients with incurable gastric cancer were treated with a combination of 5-fluorouracil (370 mg/m2) and leucovorin (30 mg/person), giv...

journal_title：Annals of surgical oncology

authors： Nakajima T,Ota K,Ishihara S,Oyama S,Nishi M,Ohashi Y,Yanagisawa A

更新日期：1997-04-01 00:00:00