Stereotactic radioguided surgery by siteSelect for subclinical mammographic lesions.

Abstract:

BACKGROUND:We defined the indications for and evaluated the results of a new technique for radioguided surgery, the SiteSelect system. The procedure allows en-bloc resection of the breast parenchyma under local anesthesia. METHODS:This prospective study was based on 167 patients operated on between December 2000 and October 2003 with 2 phases. The first step was an evaluation of the feasibility of the procedure with the 15-mm cannula, and the second was therapeutic with the 22-mm cannula. RESULTS:The mean duration of the procedure was 42 minutes. In 96.9% of procedures, the lesion was excised successfully. Only one complication (hematoma) and two failures and were observed. Histological examination revealed benign disease in 65.8% of cases and cancer in 34.2% of cases. In the latter cases, the specimen margins were histologically involved in 86.2% of cases with the 15-mm procedure and in 41% with the 22-mm procedure. During the first evaluation, all patients with a cancer underwent systematic surgical re-excision: residual tumor was present in 18 cases (64.2%). The biopsy was painless for 88 patients, and the cosmetic result was good in all cases. CONCLUSIONS:This study shows that the SiteSelect procedure allows resection of the lesion in 96.9% of cases. Combined with complementary surgical lumpectomy during the same operation, this procedure achieved a success rate of 98.7%. In the case of cancer, the 15-mm cannula is not wide enough to allow free margins. The use of a new 22-mm cannula, currently under evaluation, might solve this problem.

journal_name

Ann Surg Oncol

authors

Doridot V,Meunier M,El Khoury C,Nos C,Vincent-Salomon A,Sigal-Zafrani B,Clough KB,Institut Curie Breast Cancer Group.

doi

10.1245/ASO.2005.01.004

keywords:

subject

Has Abstract

pub_date

2005-02-01 00:00:00

pages

181-8

issue

2

eissn

1068-9265

issn

1534-4681

journal_volume

12

pub_type

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