Incidental and nonincidental papillary thyroid microcarcinoma.

Abstract:

BACKGROUND:Subtotal thyroidectomy or lobectomy without radioactive iodide ((131)I) treatment is sufficient for postoperative treatment of incidental papillary thyroid microcarcinoma (PTMC). Aggressive surgical treatment with (131)I therapy is indicated for nonincidental PTMC. METHODS:This is a retrospective analysis of 335 PTMC patients who received primary thyroid surgical treatment and long-term follow-up in a single medical center. All PTMC patients were categorized as incidental (group I) or nonincidental (group II). Group II patients (209 cases) were categorized as intrathyroid (group II A), neck lymph node or local regional soft-tissue invasion (group II B) and distant metastasis (group II C) groups. RESULTS:In group I, 105 of 126 cases received only subtotal thyroidectomy or lobectomy. None died of thyroid cancer. Histological evaluation revealed multicentric PTMC in 12 (9.5%) and 52 (24.9%) cases (P < 0.05) in groups I and II, respectively. In group II, 55 of the 209 patients (26.3%) presented with extrathyroidal involvement. Two cases of relapse occurred in group I and 20 in group II by the end of follow-up. One patient in group II B and two patients in group II C died of thyroid cancer. Nine out of ten patients in group II C were diagnosed with distant metastases before primary thyroid surgical treatment. CONCLUSION:Subtotal thyroidectomy is effective surgical treatment for incidental PTMC. For nonincidental cases, aggressive treatment is essential for reducing the risk of cancer relapse or mortality following surgery.

journal_name

Ann Surg Oncol

authors

Lin JD,Kuo SF,Chao TC,Hsueh C

doi

10.1245/s10434-008-9958-2

subject

Has Abstract

pub_date

2008-08-01 00:00:00

pages

2287-92

issue

8

eissn

1068-9265

issn

1534-4681

journal_volume

15

pub_type

杂志文章
  • Prognostic significance of the highest peripancreatic lymph node in biliary tract adenocarcinoma.

    abstract:BACKGROUND:Patients with biliary tract adenocarcinoma with nodal involvement have a poor prognosis. There is currently no standardized method for intraoperative lymph node assessment. The current study aimed to determine the prognostic significance of the highest peripancreatic lymph node (HPLN) in biliary tract malign...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-013-3352-4

    authors: Kelly KJ,Dukleska K,Kuk D,Kingham TP,D'Angelica MI,DeMatteo RP,Allen PJ,Jarnagin WR,Fong Y

    更新日期:2014-03-01 00:00:00

  • Association between recency of last pregnancy and biologic subtype of breast cancer.

    abstract:BACKGROUND:Breast cancers (BCs) diagnosed after a recent pregnancy display features associated with poor prognosis, including hormone receptor negativity, but other tumor markers have not been examined. We sought to define the tumor marker profile of these cancers, including HER-2 and p53 expression, and examine the ti...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-011-2104-6

    authors: Pilewskie M,Gorodinsky P,Fought A,Hansen N,Bethke K,Jeruss J,Scholtens D,Khan SA

    更新日期:2012-04-01 00:00:00

  • Reduced Port Laparoscopic Distal Gastrectomy with D2 Lymphadenectomy.

    abstract:BACKGROUND:Reduced port laparoscopic surgery (RPLS), as a more minimally invasive treatment alternative to conventional laparoscopic surgery (CLS), has been increasing in recent years. 1 With the accumulation of surgical experience and improvements in surgical techniques, the indication of RPLS has been gradually exten...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-017-6066-1

    authors: Lin T,Mou TY,Hu YF,Liu H,Li TJ,Lu YM,Yu J,Li GX

    更新日期:2018-01-01 00:00:00

  • Nrf2 is useful for predicting the effect of chemoradiation therapy on esophageal squamous cell carcinoma.

    abstract:BACKGROUND:The transcription factor NF-E2-related factor 2 (Nrf2) was originally identified to be a critical regulator of intracellular antioxidants and phase II detoxification enzymes. Recent studies have shown that high Nrf2 expression gives cancer cells an advantage for survival from anticancer chemotherapy and radi...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-014-3600-2

    authors: Kawasaki Y,Okumura H,Uchikado Y,Kita Y,Sasaki K,Owaki T,Ishigami S,Natsugoe S

    更新日期:2014-07-01 00:00:00

  • Stereotactic fine-needle aspiration biopsy for the evaluation of nonpalpable breast lesions: report of an experience based on 2,988 cases.

    abstract:BACKGROUND:The increasing use of mammography has led to a significant increase in the detection of clinically occult lesions, the majority of which prove to be benign. SFNB has been suggested as a means of expediting a diagnosis for lesions that are malignant while limiting surgical biopsies for those that are benign. ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1007/BF02305799

    authors: Mitnick JS,Vazquez MF,Pressman PI,Harris MN,Roses DF

    更新日期:1996-03-01 00:00:00

  • Cholangiocarcinoma Heterogeneity Revealed by Multigene Mutational Profiling: Clinical and Prognostic Relevance in Surgically Resected Patients.

    abstract:BACKGROUND:Cholangiocarcinoma can be classified in intrahepatic cholangiocarcinoma (ICC) and perihilar cholangiocarcinoma (PCC). Moreover, PCC includes two different forms: extrahepatic (EH) PCC, which arises from the perihilar EH large ducts, and intrahepatic (IH) PCC, in which a significant liver mass invades the per...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-015-5046-6

    authors: Ruzzenente A,Fassan M,Conci S,Simbolo M,Lawlor RT,Pedrazzani C,Capelli P,D'Onofrio M,Iacono C,Scarpa A,Guglielmi A

    更新日期:2016-05-01 00:00:00

  • Use of multimodality neoadjuvant therapy for esophageal cancer in the United States: assessment of 987 hospitals.

    abstract:BACKGROUND:Consensus guidelines recommend neoadjuvant therapy in locally advanced esophageal cancer; however, whether this recommendation has been widely adopted is unknown. Therefore, we evaluated the utilization of neoadjuvant therapy in esophageal cancer and its association with outcomes in the United States. METHO...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-011-1945-3

    authors: Merkow RP,Bilimoria KY,McCarter MD,Chow WB,Ko CY,Bentrem DJ

    更新日期:2012-02-01 00:00:00

  • Outcomes of > 1300 Nipple-Sparing Mastectomies with Immediate Reconstruction: The Impact of Expanding Indications on Complications.

    abstract:BACKGROUND:The enhanced esthetics and demonstrated oncologic safety of nipple-sparing mastectomy (NSM) in selected patients have resulted in increased rates among patients with locally advanced breast cancer and/or additional risk factors (obesity, prior radiation, surgery). Limited data exist on complication and recon...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-019-07560-z

    authors: Young WA,Degnim AC,Hoskin TL,Jakub JW,Nguyen MD,Tran NV,Harless CA,Manrique OJ,Boughey JC,Hieken TJ

    更新日期:2019-10-01 00:00:00

  • Granulomatous mastitis: a New York public hospital experience.

    abstract:BACKGROUND:Granulomatous mastitis is an uncommon chronic inflammatory breast condition that is characterized by granulomatous inflammation. Granulomatous mastitis presents a challenging clinical scenario, because it can mimic carcinoma. The etiology and optimal treatment remain unclear. We report our experience with gr...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-014-3895-z

    authors: Joseph KA,Luu X,Mor A

    更新日期:2014-12-01 00:00:00

  • Implications of a postoperative rehabilitation program on quality of life in women with primary breast cancer treated with sentinel lymph node biopsy or complete axillary lymph node dissection.

    abstract:BACKGROUND:The aim of this clinical study was to evaluate quality of life (QoL) in early-stage breast cancer patients and to investigate the effects of a comprehensive rehabilitation program comparing women undergoing sentinel node biopsy (SNB) versus complete axillary lymph node dissection (ALND). QoL was assessed wit...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,随机对照试验

    doi:10.1245/s10434-008-0161-2

    authors: Pinto e Silva MP,Sarian LO,Morais SS,Pace do Amaral MT,Freire de Oliveira MM,Derchain S

    更新日期:2008-12-01 00:00:00

  • Positive Ultrasound-guided Lymph Node Needle Biopsy in Breast Cancer may not Mandate Axillary Lymph Node Dissection.

    abstract:BACKGROUND:The ACOSOG Z0011 (Z11) trial demonstrated that in patients with nonpalpable axillary lymph nodes (LN) and one to two positive sentinel LN (SLN), axillary LN dissection (ALND) is unnecessary.JAMA 305:569-575, [2011], Ann Surg 264:413-42, [2016] The Z11 trial did not require preoperative axillary ultrasound (a...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-017-5935-y

    authors: Harris CK,Tran HT,Lee K,Mylander C,Pack D,Rosman M,Tafra L,Umbricht CB,Andrade R,Liang W,Jackson RS

    更新日期:2017-10-01 00:00:00

  • Lymph node metastases in diffuse malignant peritoneal mesothelioma.

    abstract:BACKGROUND:Improved survival has been reported for diffuse malignant peritoneal mesothelioma (DMPM) treated by surgical cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC). The significance of lymph node involvement in this disease is still poorly understood. METHODS:Prospectively collected clinical da...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-009-0756-2

    authors: Baratti D,Kusamura S,Cabras AD,Laterza B,Balestra MR,Deraco M

    更新日期:2010-01-01 00:00:00

  • Influence of Age on the Clinical Outcome of Breast Cancer for Men and the Development of Second Primary Cancers.

    abstract:BACKGROUND:Low incidence of breast cancer in men (BCM) (< 1% of all breast cancers) has led to a paucity of outcome data. This study evaluated the impact of age on BCM outcomes. METHODS:For this study, BCM patients treated between 2000 and 2011 were stratified by age (≤ 65 or > 65 years). Kaplan-Meier methods were use...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-018-6767-0

    authors: Cronin PA,Romanoff A,Zabor EC,Stempel M,Eaton A,Smyth LM,Ho AY,Morrow M,El-Tamer M,Gemignani ML

    更新日期:2018-12-01 00:00:00

  • Does Failure to Achieve Pathologic Complete Response with Neoadjuvant Chemotherapy Identify Node-Negative Patients Who Would Benefit from Postmastectomy Radiation or Regional Nodal Irradiation?

    abstract:BACKGROUND:Postmastectomy radiation (PMRT) and regional nodal irradiation (RNI) improve outcomes for patients at high risk of locoregional recurrence (LRR). Node-negative patients with the triple-negative (TN) subtype and those who do not have a pCR with neoadjuvant chemotherapy (NAC) are at increased risk for LRR, but...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-020-09136-8

    authors: Crown A,Gonen M,Le T,Morrow M

    更新日期:2020-09-21 00:00:00

  • Long-term outcomes in patients with calciphylaxis from hyperparathyroidism.

    abstract:BACKGROUND:Calciphylaxis is a rare condition associated with chronic renal failure and entails a very poor prognosis. Pathogenesis is poorly understood but involves abnormalities in calcium and phosphorus metabolism that lead to vascular and extravascular calcification. Patients present with painful ulcerating plaques ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/ASO.2006.03.042

    authors: Duffy A,Schurr M,Warner T,Chen H

    更新日期:2006-01-01 00:00:00

  • ASO Author Reflections: Surgery and Bevacizumab in Ovarian Cancer.

    abstract:: ...

    journal_title:Annals of surgical oncology

    pub_type: 评论,杂志文章

    doi:10.1245/s10434-018-7024-2

    authors: Petrillo M,Scambia G,Fagotti A

    更新日期:2018-12-01 00:00:00

  • Neoadjuvant Chemoradiotherapy and Tumor Recurrence in Patients with Early T-Stage Cancer of the Lower Rectum.

    abstract:BACKGROUND:The role neoadjuvant chemoradiotherapy (nCRT) plays in oncological outcomes in early T-stage rectal cancer is uncertain. The present work aims to clarify prognostic outcomes by estimating the effect of nCRT on tumor recurrence prior to major surgery compared with major surgery alone. PATIENTS AND METHODS:Pr...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1245/s10434-019-08105-0

    authors: Hayes IP,Milanzi E,Gibbs P,Reece JC

    更新日期:2020-05-01 00:00:00

  • Polymorphisms of p16, p27, p73, and MDM2 modulate response and survival of pancreatic cancer patients treated with preoperative chemoradiation.

    abstract::Genetic polymorphisms play an important role in clinical response to cytotoxic therapies. We hypothesized that polymorphisms in cell cycle genes may modulate response to preoperative chemoradiation and survival of pancreatic cancer patients. We evaluated 12 single-nucleotide polymorphisms (SNPs) of ten cell cycle gene...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-008-0220-8

    authors: Chen J,Li D,Killary AM,Sen S,Amos CI,Evans DB,Abbruzzese JL,Frazier ML

    更新日期:2009-02-01 00:00:00

  • Tumor size as a simple prognostic indicator for gastric carcinoma.

    abstract:BACKGROUND:Tumor size can be measured easily before or during operation with no special tools, but its prognostic use in patients with gastric carcinoma is still unclear. METHODS:Clinicopathologic data of 479 patients who underwent curative operation for gastric carcinoma were studies. The relationship between tumor s...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1007/BF02303796

    authors: Adachi Y,Oshiro T,Mori M,Maehara Y,Sugimachi K

    更新日期:1997-03-01 00:00:00

  • Robot-assisted spleen-preserving laparoscopic distal pancreatectomy.

    abstract:BACKGROUND:Spleen-preserving laparoscopic distal pancreatectomy would be an ideal approach for benign and borderline malignant tumors in the distal pancreas.1 However, this procedure requires advanced surgical experience and technique because of the disadvantages of conventional laparoscopic surgery.2 METHODS:A 35-yea...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-011-1816-y

    authors: Choi SH,Kang CM,Lee WJ,Chi HS

    更新日期:2011-12-01 00:00:00

  • Oncotype DX® Recurrence Score as a Predictor of Response to Neoadjuvant Chemotherapy.

    abstract:BACKGROUND:The Oncotype DX® assay has been validated in predicting response to adjuvant chemotherapy in breast cancer. Its role in neoadjuvant chemotherapy (NCT) has not been established. METHODS:The National Cancer Database was used to identify all patients with T1-T3, ER-positive, HER2-negative primary invasive brea...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-018-07107-8

    authors: Pease AM,Riba LA,Gruner RA,Tung NM,James TA

    更新日期:2019-02-01 00:00:00

  • Dynamic contrast enhanced magnetic resonance imaging of the breast is superior to triple assessment for the pre-operative detection of multifocal breast cancer.

    abstract:BACKGROUND:Inadequately treated multifocal and multicentric disease results in increased local recurrence following breast-conserving surgery. The accurate preoperative diagnosis of multifocal/ centric breast cancer would facilitate the planning of appropriate surgery and prevent reoperation for residual disease. While...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1007/s10434-999-0599-x

    authors: Drew PJ,Chatterjee S,Turnbull LW,Read J,Carleton PJ,Fox JN,Monson JR,Kerin MJ

    更新日期:1999-09-01 00:00:00

  • Msi-1 is a predictor of survival and a novel therapeutic target in colon cancer.

    abstract:BACKGROUND:Musashi1 (Msi-1), a neural RNA-binding protein, plays an important role in regulating cell differentiation in precursor cells. Recently, aberrant expression of Msi-1 has been detected in several malignancies. However, its role in the progression of colon cancer is largely unknown. MATERIALS AND METHODS:We u...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-011-1567-9

    authors: Li D,Peng X,Yan D,Tang H,Huang F,Yang Y,Peng Z

    更新日期:2011-07-01 00:00:00

  • Impact of BRCA1/2 Mutations on the Efficacy of Secondary Cytoreductive Surgery.

    abstract:BACKGROUND:Phase III trials evaluating the role of secondary cytoreductive surgery (SCS) in recurrent ovarian cancer have pointed to the importance of patient selection. Two studies showed conflicting results regarding the benefit of SCS in BRCA1/2 mutation carriers. Our aim was to evaluate the impact of SCS on recurre...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-020-09366-w

    authors: Estati FL,Pirolli R,de Alencar VTL,Ribeiro ARG,Formiga MN,Torrezan GT,Carraro DM,Guimarães APG,Baiocchi G,da Costa AABA

    更新日期:2020-11-21 00:00:00

  • Lymphatic drainage patterns from the treated breast.

    abstract:INTRODUCTION:Lymphatic drainage patterns from the breast have been described in the past. Drainage may change after treatment of a breast or axilla, and this may have implications for lymphatic mapping. The aim of this study was to determine the lymphatic drainage patterns in breast cancer patients with a previously tr...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-009-0841-6

    authors: van der Ploeg IM,Oldenburg HS,Rutgers EJ,Baas-Vrancken Peeters MJ,Kroon BB,Valdés Olmos RA,Nieweg OE

    更新日期:2010-04-01 00:00:00

  • Comprehensive needs assessment of clinical breast evaluation skills of primary care residents.

    abstract:BACKGROUND:Health care reform places primary care (PC) physicians in an increasingly significant role for breast cancer screening and diagnosis. This study assessed the adequacy of traditional PC resident training to prepare physicians for this front-line role. METHODS:Sixty-eight primary care residents, representing ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1007/BF02303850

    authors: Chalabian J,Formenti S,Russell C,Pearce J,Dunnington G

    更新日期:1998-03-01 00:00:00

  • Comparison of survival of patients with BCLC stage A hepatocellular carcinoma after hepatic resection or transarterial chemoembolization: a propensity score-based analysis.

    abstract:BACKGROUND:It is unclear whether hepatic resection (HR) or transarterial chemoembolization (TACE) is associated with better outcomes for patients with hepatocellular carcinoma (HCC) in Barcelona Clinic Liver Cancer (BCLC) stage A. The present study compared survival for patients with BCLC stage A HCC treated by HR or T...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-014-3704-8

    authors: Guo Z,Zhong JH,Jiang JH,Zhang J,Xiang BD,Li LQ

    更新日期:2014-09-01 00:00:00

  • Closure of Melanoma Defects on the Sole of the Foot Using Glaborous Skin: The End of the Flap?

    abstract:INTRODUCTION:Plantar melanomas are a challenge to reconstruct after wide excision. Non-glaborous skin grafts have resulted in tissue loss, hyperkeratosis, marginal scarring, and poor functional outcomes, leading many to utilize various flaps for reconstruction that are technically demanding and associated with increase...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-015-4449-8

    authors: Maker AV,Iteld L

    更新日期:2015-11-01 00:00:00

  • Trends in centralization of cancer surgery.

    abstract:BACKGROUND:The association between procedure volume and clinical outcomes has led many to advocate centralization of cancer procedures at high-volume centers (HVCs). Regional studies show practice patterns changing with increasing centralization of esophageal and pancreatic procedures at HVCs but little change for colo...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-010-1159-0

    authors: Stitzenberg KB,Meropol NJ

    更新日期:2010-11-01 00:00:00

  • EGFR and p53 status of pulmonary pleomorphic carcinoma: implications for EGFR tyrosine kinase inhibitors therapy of an aggressive lung malignancy.

    abstract:BACKGROUND:Pleomorphic carcinomas of the lung are uncommon malignant tumors composed of carcinomatous and sarcomatous components and are distinguished from other non-small-cell lung carcinomas by a more aggressive clinical course with early distant metastases and far worse survival. Epidermal growth factor receptor (EG...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-011-1621-7

    authors: Chang YL,Wu CT,Shih JY,Lee YC

    更新日期:2011-10-01 00:00:00