当前位置： SCI文献检索 > ANNALS OF SURGICAL ONCOLOGY期刊下所有文献 > Association between recency of last pregnancy and biologic subtype of breast cancer.

Association between recency of last pregnancy and biologic subtype of breast cancer.

Abstract：

BACKGROUND:Breast cancers (BCs) diagnosed after a recent pregnancy display features associated with poor prognosis, including hormone receptor negativity, but other tumor markers have not been examined. We sought to define the tumor marker profile of these cancers, including HER-2 and p53 expression, and examine the time interval over which this adverse profile is observed, relative to last pregnancy. METHODS:A prospectively maintained database was reviewed to identify women with a BC diagnosis between 1998 to 2011. Parous women were categorized on the basis of the interval between pregnancy and BC diagnosis; 0-2 years, >2-5 years, >5-10 years, and >10-15 years. Tumor characteristics of parous cases were compared to those of nulliparous BC patients, who were frequency matched by age. RESULTS:A total of 175 parous and 114 nulliparous women were identified. Women who were 0-2 years from last parity at the time of BC diagnosis were the only group who were more likely than control women to have grade 3 tumors (P<0.01), positive lymph nodes (P=0.02), and triple negative tumors (P=0.01, odds ratio 3.2, 95% confidence interval 1.2-8.5). There was no difference noted in HER-2 or p53 status relative to interval from pregnancy. CONCLUSIONS:BC diagnosed within 2 years of pregnancy is more likely to have poor prognostic features and to be triple negative. More work is needed to delineate the time frame of pregnancy-associated BC and to define them on a molecular level, so as to devise better prevention and therapy for this devastating problem.

journal_name

Ann Surg Oncol

journal_title

Annals of surgical oncology

authors

Pilewskie M,Gorodinsky P,Fought A,Hansen N,Bethke K,Jeruss J,Scholtens D,Khan SA

doi

10.1245/s10434-011-2104-6

subject

Has Abstract

pub_date

2012-04-01 00:00:00

pages

1167-73

issue

4

eissn

1068-9265

issn

1534-4681

journal_volume

19

pub_type

杂志文章

相关文献

ANNALS OF SURGICAL ONCOLOGY文献大全
  • Local recurrence and survival in soft-tissue sarcomas.

    abstract：BACKGROUND:There is a continuous interest in the literature concerning the management and survival after treatment of local recurrence in sarcomas because it is one of the most common types of recurrence. DESIGN:We retrospectively reviewed 93 patients treated for local recurrence from soft-tissue sarcoma. METHODS:We ...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1007/BF02306280

    authors： Karakousis CP,Proimakis C,Rao U,Velez AF,Driscoll DL

    更新日期：1996-05-01 00:00:00

  • Prognostic value of cytokeratin-positive bone marrow cells of gastric cancer patients.

    abstract：BACKGROUND:Epithelial cells in the bone marrow of patients with gastric cancer suggest tumor dissemination; however, their prognostic implications are controversial. We prospectively evaluated the correlation of bone marrow findings, recurrence rate, and disease-free survival after long-term follow-up. METHODS:Bone ma...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-006-9039-3

    authors： Gretschel S,Schick C,Schneider U,Estevez-Schwarz L,Bembenek A,Schlag PM

    更新日期：2007-02-01 00:00:00

  • ASO Author Reflections: Proposal of a New Preoperative Prognostic Model for Solitary Hepatocellular Carcinoma.

    abstract：: ...

    journal_title：Annals of surgical oncology

    pub_type： 评论,杂志文章

    doi：10.1245/s10434-018-6796-8

    authors： Yoh T,Seo S

    更新日期：2018-12-01 00:00:00

  • Identification of the NEDD4L gene as a prognostic marker by integrated microarray analysis of copy number and gene expression profiling in non-small cell lung cancer.

    abstract：PURPOSE:The purpose of this study was to identify prognostic genes by integrated microarray analysis between comparative genomic hybridization and gene expression with laser microdissection in non-small cell lung cancer (NSCLC). METHODS:Integrated microarray analysis in 11 lung adenocarcinomas was performed, and sever...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-013-3059-6

    authors： Sakashita H,Inoue H,Akamine S,Ishida T,Inase N,Shirao K,Mori M,Mimori K

    更新日期：2013-12-01 00:00:00

  • Influence of Food Intake on the Healing Process of Postoperative Pancreatic Fistula After Pancreatoduodenectomy: A Multi-institutional Randomized Controlled Trial.

    abstract：BACKGROUND:The usefulness of enteral nutrition via a nasointestinal tube for patients who develop postoperative pancreatic fistula (POPF) after miscellaneous pancreatectomy procedures has been reported. However, no clear evidence regarding whether oral intake is possible during management of POPF after pancreatoduodene...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1245/s10434-015-4496-1

    authors： Fujii T,Nakao A,Murotani K,Okamura Y,Ishigure K,Hatsuno T,Sakai M,Yamada S,Kanda M,Sugimoto H,Nomoto S,Takeda S,Morita S,Kodera Y

    更新日期：2015-11-01 00:00:00

  • Hilar cholangiocarcinoma: a review and commentary.

    abstract：:Hilar cholangiocarcinoma is an uncommon cause of malignant biliary obstruction marked by local tumor spread for which surgery offers the only chance of cure. The diagnostic evaluation and surgical management of this disease continues to evolve. Although direct cholangiography and endoscopic biliary procedures have bee...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,评审

    doi：10.1007/s10434-000-0055-4

    authors： Chamberlain RS,Blumgart LH

    更新日期：2000-01-01 00:00:00

  • Management of locoregional and systemic recurrence of breast cancer: to stage or not to stage and how.

    abstract：:The surveillance of breast cancer patients after potentially curative treatment may result in the identification of locoregional or distant recurrence. While many patients expect frequent imaging studies to monitor for recurrence, there are no data supporting aggressive imaging surveillance beyond mammography. However...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-013-3180-6

    authors： Leitch AM

    更新日期：2013-10-01 00:00:00

  • Reoperation for Complications after Lumpectomy and Mastectomy for Breast Cancer from the 2012 National Surgical Quality Improvement Program (ACS-NSQIP).

    abstract：BACKGROUND:Hospital readmissions and reoperations are quality indicators of patient care. In 2012, the National Surgical Quality Improvement Program (ACS-NSQIP) began reporting details regarding unplanned reoperations within 30 days of initial procedure. The main objective of this study was to identify reoperation rate...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-015-4741-7

    authors： Al-Hilli Z,Thomsen KM,Habermann EB,Jakub JW,Boughey JC

    更新日期：2015-12-01 00:00:00

  • Survival of Patients with Uterine Carcinosarcoma Undergoing Sentinel Lymph Node Mapping.

    abstract：PURPOSE:This study was designed to evaluate the outcome of patients with uterine carcinosarcoma undergoing sentinel lymph node (SLN) mapping. METHODS:A prospectively maintained database was reviewed for all women with uterine cancer treated at our institution from January 1, 1998 to August 31, 2014. Patients were grou...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-015-4612-2

    authors： Schiavone MB,Zivanovic O,Zhou Q,Leitao MM Jr,Levine DA,Soslow RA,Alektiar KM,Makker V,Iasonos A,Abu-Rustum NR

    更新日期：2016-01-01 00:00:00

  • Skeletal metastases in myxoid liposarcoma: an unusual pattern of distant spread.

    abstract：BACKGROUND:Myxoid liposarcoma (MLS), the second most common subtype of liposarcoma, occurs predominantly in the extremities of young adults and has a disproportionately high tendency to metastasize to unusual soft tissue locations, before disseminated spread or pulmonary metastases. Anecdotal evidence, mainly supported...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-006-9306-3

    authors： Schwab JH,Boland P,Guo T,Brennan MF,Singer S,Healey JH,Antonescu CR

    更新日期：2007-04-01 00:00:00

  • Systematic para-aortic and pelvic lymphadenectomy in early stage epithelial ovarian cancer: a prospective study.

    abstract：BACKGROUND:Lymphadenectomy is important in the surgical treatment of apparent early epithelial ovarian cancers (eEOC); however, its extent is not well defined. We evaluated the role of systematic lymphadenectomy, the risk factors related with lymph node metastases, the implications, and the morbidity of comprehensive s...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-012-2439-7

    authors： Ditto A,Martinelli F,Reato C,Kusamura S,Solima E,Fontanelli R,Haeusler E,Raspagliesi F

    更新日期：2012-11-01 00:00:00

  • Patients Treated at Low-Volume Centers have Higher Rates of Incomplete Resection and Compromised Outcomes: Analysis of 31,129 Patients with Papillary Thyroid Cancer.

    abstract：BACKGROUND:Data on the importance of margin status after total thyroidectomy for papillary thyroid cancer (PTC) remain limited. This study sought to identify factors associated with positive margins and to determine the impact of positive margins on survival for patients with PTC. METHODS:The National Cancer Data Base...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-015-4867-7

    authors： Youngwirth LM,Adam MA,Scheri RP,Roman SA,Sosa JA

    更新日期：2016-02-01 00:00:00

  • Retrospective evaluation of the influence of postoperative tumor marker status on survival and patterns of recurrence after surgery for pancreatic cancer based on RECIST guidelines.

    abstract：PURPOSE:The purpose of this study was to obtain a comprehensive understanding of the impact of postoperative tumor marker (TM) normalization on survival after pancreatectomy for pancreatic carcinoma. We propose the concept of surgical RECIST based on residual tumor and TM status. METHODS:A total of consecutive patient...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-010-1311-x

    authors： Motoi F,Rikiyama T,Katayose Y,Egawa S,Unno M

    更新日期：2011-02-01 00:00:00

  • Total Laparoscopic Pancreaticoduodenectomy with Venous Reconstruction for Pancreatic Head Cancer with Involvement of the Superior Mesenteric Vein-Portal Vein Confluence.

    abstract：BACKGROUND:Laparoscopic pancreaticoduodenectomy with venous reconstruction is not commonly performed due to its technical challenges. In this video, we focus on the technical aspects for how to perform this procedure safely. METHODS:In a 69-year-old female with jaundice and diarrhea, a computed tomography scan showed ...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-018-6762-5

    authors： Garbarino GM,Fuks D,Cowan J,Ward M,Moisan F,Donatelli G,Beaussier M,Gayet B

    更新日期：2018-12-01 00:00:00

  • Surveillance of Low-Grade Appendiceal Mucinous Neoplasms With Peritoneal Metastases After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: Are 5 Years Enough? A Multisite Experience.

    abstract：BACKGROUND:Low-grade appendiceal mucinous neoplasms (LAMNs) are tumors that often present with widespread mucin in the peritoneal cavity (pseudomyxoma peritonei [PMP]). Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are effective treatment, but no published recommendations exist regar...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,多中心研究

    doi：10.1245/s10434-019-07678-0

    authors： Solomon D,Bekhor E,Leigh N,Maniar YM,Totin L,Hofstedt M,Aycart SN,Carr J,Ballentine S,Magge DR,Golas BJ,Pai RK,Polydorides AD,Bartlett DL,Labow DM,Choudry HA,Sarpel U

    更新日期：2020-01-01 00:00:00

  • Prospective study of outcomes after percutaneous biliary drainage for malignant biliary obstruction.

    abstract：BACKGROUND:Percutaneous biliary drainage (PBD) is used to relieve malignant bile duct obstruction (MBO) when endoscopic drainage is not feasible. Little is known about the effects of PBD on the quality of life (QoL) in patients with MBO. The aim of this study was to evaluate changes in QoL and pruritus after PBD and to...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-010-1045-9

    authors： Robson PC,Heffernan N,Gonen M,Thornton R,Brody LA,Holmes R,Brown KT,Covey AM,Fleischer D,Getrajdman GI,Jarnagin W,Sofocleous C,Blumgart L,D'Angelica M

    更新日期：2010-09-01 00:00:00

  • Adenocarcinomas of the esophagogastric junction are more likely to respond to preoperative chemotherapy than distal gastric cancer.

    abstract：BACKGROUND:Preoperative chemotherapy has been shown to improve outcome of patients with adenocarcinoma of the esophagogastric junction (AEG) and gastric cancer (GC), and histopathologic response has been identified as an independent prognostic parameter in these patients. A recent meta-analysis has identified patients ...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-011-2147-8

    authors： Reim D,Gertler R,Novotny A,Becker K,zum Büschenfelde CM,Ebert M,Dobritz M,Langer R,Hoefler H,Friess H,Schumacher C

    更新日期：2012-07-01 00:00:00

  • p53 genotype predicts response to chemotherapy in patients with squamous cell carcinoma of the esophagus.

    abstract：BACKGROUND:Response to chemotherapy and anatomical spread are significant prognostic factors in patients with esophageal squamous cell carcinoma (ESCC) treated by chemotherapy then surgery. Predicting the response to chemotherapy would allow significant optimization of cancer treatment. METHODS:Genomic mutation and pr...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-009-0851-4

    authors： Yamasaki M,Miyata H,Fujiwara Y,Takiguchi S,Nakajima K,Nishida T,Yasuda T,Matsuyama J,Mori M,Doki Y

    更新日期：2010-02-01 00:00:00

  • Prognostic significance of splenectomy as part of initial cytoreductive surgery in ovarian cancer.

    abstract：PURPOSE:We sought to examine how splenectomy as part of up-front cytoreductive surgery in ovarian cancer influences the postoperative course and affects survival. METHODS:We reviewed cases of ovarian cancer diagnosed at Massachusetts General Hospital from 1994 to 2008 and found 44 patients who had a splenectomy as par...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,随机对照试验

    doi：10.1245/s10434-011-1661-z

    authors： McCann CK,Growdon WB,Munro EG,Del Carmen MG,Boruta DM,Schorge JO,Goodman A

    更新日期：2011-10-01 00:00:00

  • The utility of intraoperative evaluation of sentinel lymph nodes in breast cancer.

    abstract：BACKGROUND:In breast cancer treatment, intraoperative sentinel lymph node (SLN) evaluation is used to identify patients who may potentially benefit from immediate completion of axillary lymph node dissection. METHODS:Prospectively collected breast cancer registry data identified 516 SLN biopsies between January 2003 a...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-006-9270-y

    authors： Pugliese MS,Tickman R,Wang NP,Atwood M,Beatty JD

    更新日期：2007-03-01 00:00:00

  • Radiographic Surveillance of Patients with Non-BRCA1/2 Pathogenic Variants.

    abstract：INTRODUCTION:The National Comprehensive Cancer Network (NCCN) developed clinical practice guidelines for germline pathogenic variants in highly penetrant genes, such as TP53 and PTEN, and in moderately penetrant genes, such as CHEK2, ATM and PALB2. Whether the practice of radiographic surveillance of patients with path...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-019-08191-0

    authors： Hudson L,Gower N,Lenarcic S,Trufan SJ,White RL Jr

    更新日期：2020-07-01 00:00:00

  • Preoperative staging of rectal cancer with MRI: accuracy and clinical usefulness.

    abstract：BACKGROUND:Preoperative staging is essential for planning of optimal therapy for patients with rectal cancer. Recently, magnetic resonance imaging (MRI) is used frequently because of its benefits of clear pelvic image are better than other diagnostic methods. The purpose of this study was to determine accuracy rates an...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1007/s10434-000-0732-3

    authors： Kim NK,Kim MJ,Park JK,Park SI,Min JS

    更新日期：2000-12-01 00:00:00

  • Intrathoracic Chemoperfusion Decreases Recurrences in Patients with Full-Thickness Diaphragm Involvement with Mucinous Appendiceal Adenocarcinoma.

    abstract：BACKGROUND:Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) is the preferred treatment for selected patients with mucinous appendiceal adenocarcinoma. Frequently, the hemidiaphragms are infiltrated with tumor, requiring partial diaphragm resection (DR) in order to obtain complete cytoreductio...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-016-5209-0

    authors： Grotz TE,Mansfield PF,Royal RE,Mann GN,Rafeeq S,Beaty KA,Overman MJ,Fournier KF

    更新日期：2016-09-01 00:00:00

  • CpG island methylator phenotype associated with tumor recurrence in tumor-node-metastasis stage I hepatocellular carcinoma.

    abstract：BACKGROUND:CpG island methylator phenotype (CIMP), characterized by simultaneous methylation of multiple tumor suppressor genes (TSGs), has been reported to be associated with biological malignancy in many cancers. Whether CIMP is potentially predictive of clinical outcome in hepatocellular carcinoma (HCC) remains unkn...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-010-0921-7

    authors： Li B,Liu W,Wang L,Li M,Wang J,Huang L,Huang P,Yuan Y

    更新日期：2010-07-01 00:00:00

  • Minimally Invasive Approaches in Locally Advanced Cervical Cancer Patients Undergoing Radical Surgery After Chemoradiotherapy: A Propensity Score Analysis.

    abstract：PURPOSE:Chemoradiation (CT/RT) followed by radical surgery (RS) may play a role in locally advanced cervical cancer (LACC) patients with suboptimal response to CT/RT or in low-income countries with limited access to radiotherapy. Our aim is to evaluate oncological and surgical outcomes of minimally invasive radical sur...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-020-09302-y

    authors： Ferrandina G,Gallotta V,Federico A,Fanfani F,Ercoli A,Chiantera V,Cosentino F,Turco LC,Legge F,Anchora LP,Bizzarri N,Moroni R,Macchia G,Valentini V,Scambia G

    更新日期：2020-11-09 00:00:00

  • Incidence, Risk Factors, and Prevention Strategies for Venous Thromboembolism after Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy.

    abstract：BACKGROUND:The risk factors and incidence of venous thromboembolism (VTE) are not well defined in patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC). We sought to characterize the incidence, risk factors, and pharmacothromboprophylaxis strategies for VTE after CRS/HIPEC....

    journal_title：Annals of surgical oncology

    pub_type： 临床试验,杂志文章

    doi：10.1245/s10434-019-07414-8

    authors： Khan S,Kelly KJ,Veerapong J,Lowy AM,Baumgartner JM

    更新日期：2019-07-01 00:00:00

  • Induction chemotherapy with S-1 plus cisplatin followed by surgery for treatment of gastric cancer with peritoneal dissemination.

    abstract：BACKGROUND:The prognosis of gastric cancer patients with peritoneal dissemination is poor. Recently, chemotherapy with S-1 plus cisplatin has been shown to be highly effective for advanced gastric cancer. METHODS:In 41 patients diagnosed with either macro- or microscopic peritoneal dissemination by staging laparoscopy...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-009-0706-z

    authors： Okabe H,Ueda S,Obama K,Hosogi H,Sakai Y

    更新日期：2009-12-01 00:00:00

  • Factors associated with variance in compliance with a sentinel lymph node dissection quality measure in early-stage breast cancer.

    abstract：BACKGROUND:Guidelines recommend sentinel lymph node dissection (SLND) for patients with clinical stage I/IIA/IIB breast cancer; however, a significant fraction of patients do not undergo this procedure. We sought to identify factors associated with noncompliance with the SLND benchmark in early-stage breast cancer. MA...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-010-1248-0

    authors： Olaya W,Wong J,Morgan JW,Truong C,Roy-Chowdhury S,Kazanjian K,Lum S

    更新日期：2010-10-01 00:00:00

  • Young-onset rectal cancer: presentation, pattern of care and long-term oncologic outcomes compared to a matched older-onset cohort.

    abstract：BACKGROUND:Recent population-based studies have highlighted a disproportionate increase in the incidence of rectal cancer among adults younger than aged 50 years. To determine whether different intervention and surveillance strategies might be needed for younger patients, the patterns of care and oncologic outcomes amo...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-011-1674-7

    authors： You YN,Dozois EJ,Boardman LA,Aakre J,Huebner M,Larson DW

    更新日期：2011-09-01 00:00:00

  • Evaluation of malignancy risk stratification of microcalcifications detected on mammography: a study based on the 5th edition of BI-RADS.

    abstract：BACKGROUND:The 5th edition of Breast Imaging Reporting and Data System subdivides suspicious calcifications into two categories: 4B-amorphous, coarse heterogeneous, and fine pleomorphic calcifications; 4C-fine linear or fine linear branching calcifications. We investigated whether these revised categories are appropria...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-014-4362-6

    authors： Kim SY,Kim HY,Kim EK,Kim MJ,Moon HJ,Yoon JH

    更新日期：2015-09-01 00:00:00