当前位置： SCI文献检索 > ANNALS OF SURGICAL ONCOLOGY期刊下所有文献 > Systematic para-aortic and pelvic lymphadenectomy in early stage epithelial ovarian cancer: a prospective study.

Systematic para-aortic and pelvic lymphadenectomy in early stage epithelial ovarian cancer: a prospective study.

Abstract：

BACKGROUND:Lymphadenectomy is important in the surgical treatment of apparent early epithelial ovarian cancers (eEOC); however, its extent is not well defined. We evaluated the role of systematic lymphadenectomy, the risk factors related with lymph node metastases, the implications, and the morbidity of comprehensive surgical staging. METHODS:We prospectively recruited 124 patients diagnosed with apparent eEOC [International Federation of Gynecology and Obstetrics (FIGO) stage I and II] between January 2003 and January 2011. Demographics, surgical procedures, morbidities, pathologic findings, and correlations with lymph node metastases were assessed. RESULTS:A total of 111 patients underwent complete surgical staging, including lymphadenectomy, and were therefore analyzed. A median of 23 pelvic and 20 para-aortic nodes were removed. Node metastases were found in 15 patients (13.5 %). The para-aortic region was involved in 13 (86.6 %) of 15 cases. At univariate analysis, age, menopause, FIGO stage, grading, and laterality were found to be significant factors for lymph node metastases, while CA125 of >35 U/ml and positive cytology were not. No lymph node metastases were found in mucinous histotypes. At multivariate analysis, only bilaterality (p = 0.018) and menopause (p = 0.032) maintained a statistically significant association with lymph node metastases. Lymphadenectomy-related complications (lymphocyst formation and lymphorrhea) were found in 14.4 % patients. CONCLUSIONS:The data of this prospective study demonstrate the prognostic value of lymphadenectomy in eEOC. Menopause, age, bilaterality, histology, and tumor grade are identifiable factors that can help the surgeon decide whether to perform comprehensive surgical staging with lymph node dissection. These parameters may be used in planning subsequent treatment.

journal_name

Ann Surg Oncol

journal_title

Annals of surgical oncology

authors

Ditto A,Martinelli F,Reato C,Kusamura S,Solima E,Fontanelli R,Haeusler E,Raspagliesi F

doi

10.1245/s10434-012-2439-7

subject

Has Abstract

pub_date

2012-11-01 00:00:00

pages

3849-55

issue

12

eissn

1068-9265

issn

1534-4681

journal_volume

19

pub_type

杂志文章

相关文献

ANNALS OF SURGICAL ONCOLOGY文献大全
  • Prognostic Value and Prediction of Extratumoral Microvascular Invasion for Hepatocellular Carcinoma.

    abstract：BACKGROUND:There are few reports on microvascular invasion (MVI) located intra- or extratumorally and prognosis of hepatocellular carcinoma (HCC). OBJECTIVE:The aim of this study was to evaluate patient outcome according to the location of MVI, and to build a nomogram predicting extratumoral MVI. METHODS:We included ...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-019-07365-0

    authors： Nitta H,Allard MA,Sebagh M,Ciacio O,Pittau G,Vibert E,Sa Cunha A,Cherqui D,Castaing D,Bismuth H,Guettier C,Lewin M,Samuel D,Baba H,Adam R

    更新日期：2019-08-01 00:00:00

  • Prognostic Utility of Pre- and Postoperative Circulating Tumor DNA Liquid Biopsies in Patients with Peritoneal Metastases.

    abstract：BACKGROUND:Circulating tumor DNA (ctDNA) is a promising technology for treatment selection, prognostication, and surveillance after definitive therapy. Its use in the perioperative setting for patients with metastatic disease has not been well studied. We characterize perioperative plasma ctDNA and its association with...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-020-08331-x

    authors： Baumgartner JM,Riviere P,Lanman RB,Kelly KJ,Veerapong J,Lowy AM,Kurzrock R

    更新日期：2020-09-01 00:00:00

  • Nonoperative management of primary colorectal cancer in patients with stage IV disease.

    abstract：BACKGROUND:Traditional teaching maintains that patients with primary colorectal adenocarcinoma require timely resection to prevent bleeding, perforation, or obstruction. The true benefits of primary tumor resection remain undocumented for patients presenting with metastatic disease, however. We postulated that resectio...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1007/s10434-999-0651-x

    authors： Scoggins CR,Meszoely IM,Blanke CD,Beauchamp RD,Leach SD

    更新日期：1999-10-01 00:00:00

  • Population-based outcome of stage IA-IIA resected gastric adenocarcinoma: who should get adjuvant treatment?

    abstract：BACKGROUND:The benefit of adjuvant treatment in gastric adenocarcinoma was demonstrated by randomized, controlled trials of patients with locally advanced tumors. Thus, its role for stage IIB-IIIC disease is widely accepted. We aimed to identify patients with stage IA-IIA gastric adenocarcinoma who have a poor prognosi...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-012-2852-y

    authors： Gold JS,Al Natour RH,Saund MS,Yoon C,Sharma AM,Huang Q,Boosalis VA,Whang EE

    更新日期：2013-07-01 00:00:00

  • Adjuvant brachytherapy for primary high-grade soft tissue sarcoma of the extremity.

    abstract：BACKGROUND:We reviewed single-institution experience using brachytherapy alone for primary high-grade soft tissue sarcoma of the extremity. METHODS:Between July 1982 and September 1997, 202 adult patients with primary high-grade soft tissue sarcoma of the extremity were treated with limb-sparing surgery and adjuvant b...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/aso.2002.9.1.48

    authors： Alektiar KM,Leung D,Zelefsky MJ,Healey JH,Brennan MF

    更新日期：2002-01-01 00:00:00

  • Correction to: Merkel Cell Carcinoma Outcomes: Does AJCC8 Underestimate Survival?

    abstract：:C.R. Farley and M.C. Perez contributed equally to this publication and are co-first authors. J.S. Zager and M.C. Lowe contributed equally to this publication and are co-corresponding authors. ...

    journal_title：Annals of surgical oncology

    pub_type： 已发布勘误

    doi：10.1245/s10434-020-08871-2

    authors： Farley CR,Perez MC,Soelling SJ,Delman KA,Harit A,Wuthrick EJ,Messina JL,Sondak VK,Zager JS,Lowe MC

    更新日期：2020-12-01 00:00:00

  • Cure model survival analysis after hepatic resection for colorectal liver metastases.

    abstract：BACKGROUND:Statistical cure is achieved when a patient population has the same mortality as cancer-free individuals; however, data regarding the probability of cure after hepatectomy of colorectal liver metastases (CLM) have never been provided. We aimed to assess the probability of being statistically cured from CLM b...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-014-4234-0

    authors： Cucchetti A,Ferrero A,Cescon M,Donadon M,Russolillo N,Ercolani G,Stacchini G,Mazzotti F,Torzilli G,Pinna AD

    更新日期：2015-01-01 00:00:00

  • Prognostic variables in invasive breast cancer: contribution of comedo versus noncomedo in situ component.

    abstract：BACKGROUND:Many invasive breast cancers are accompanied by a variety of noninvasive components. Histological distinctions have been made between these components, but to understand their importance, it is essential to examine their molecular biology. METHODS:Proliferative indices, oncoproteins, and steroid receptor ex...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1007/BF02306378

    authors： Brower ST,Ahmed S,Tartter PI,Bleiweiss I,Amberson JB

    更新日期：1995-09-01 00:00:00

  • Does Failure to Achieve Pathologic Complete Response with Neoadjuvant Chemotherapy Identify Node-Negative Patients Who Would Benefit from Postmastectomy Radiation or Regional Nodal Irradiation?

    abstract：BACKGROUND:Postmastectomy radiation (PMRT) and regional nodal irradiation (RNI) improve outcomes for patients at high risk of locoregional recurrence (LRR). Node-negative patients with the triple-negative (TN) subtype and those who do not have a pCR with neoadjuvant chemotherapy (NAC) are at increased risk for LRR, but...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-020-09136-8

    authors： Crown A,Gonen M,Le T,Morrow M

    更新日期：2020-09-21 00:00:00

  • Predictors for major wound complications following preoperative radiotherapy and surgery for soft-tissue sarcoma of the extremities and trunk: importance of tumor proximity to skin surface.

    abstract：PURPOSE:Preoperative and postoperative RT for the treatment of high-grade soft-tissue sarcoma result in similar local control and overall survival rates, but morbidities differ. Postoperative RT is associated with a higher rate of long-term fibrosis, edema, and joint stiffness. Preoperative RT is associated with higher...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-012-2797-1

    authors： Baldini EH,Lapidus MR,Wang Q,Manola J,Orgill DP,Pomahac B,Marcus KJ,Bertagnolli MM,Devlin PM,George S,Abraham J,Ferrone ML,Ready JE,Raut CP

    更新日期：2013-05-01 00:00:00

  • High RAD18 Expression is Associated with Disease Progression and Poor Prognosis in Patients with Gastric Cancer.

    abstract：BACKGROUND:RAD18 plays an important role in DNA damage repair by inducing monoubiquitinated PCNA (mUB-PCNA) in both cancer and normal tissues. Previous studies have not determined the significance of RAD18 expression in clinical gastric cancer (GC) samples. Thus, this study aimed to clarify the expression and functiona...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-020-08518-2

    authors： Baatar S,Bai T,Yokobori T,Gombodorj N,Nakazawa N,Ubukata Y,Kimura A,Kogure N,Sano A,Sohda M,Sakai M,Tumenjargal A,Ogata K,Kuwano H,Shirabe K,Saeki H

    更新日期：2020-10-01 00:00:00

  • ASO Author Reflections: Transoral Robotic Surgery Combined with Neoadjuvant Chemotherapy for Management of Advanced Laryngohypopharyngeal Cancer.

    abstract：: ...

    journal_title：Annals of surgical oncology

    pub_type： 评论,杂志文章

    doi：10.1245/s10434-018-6850-6

    authors： Park YM,Kim SH

    更新日期：2018-12-01 00:00:00

  • Characterization of the neoplastic potential of solitary solid thyroid lesions with Tc-99m-pertechnetate and Tc-99m-sestamibi scanning.

    abstract：BACKGROUND:Radionuclide scans that use Tc-99m-pertechnetate or I-123 currently lack the specificity to assess the malignant potential of solitary solid lesions of the thyroid gland. Tc-99m-sestamibi scanning was used to determine the neoplastic potential of thyroid lesions. METHODS:Patients with lesions of the thyroid...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1007/BF02307029

    authors： Wei JP,Burke GJ

    更新日期：1995-05-01 00:00:00

  • Phase II Trial of Neoadjuvant Chemotherapy, Chemoradiotherapy, and Laparoscopic Surgery with Selective Lateral Node Dissection for Poor-Risk Low Rectal Cancer.

    abstract：PURPOSE:The aim of this study is to evaluate the safety and efficacy of induction modified 5-fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) plus bevacizumab followed by S- 1-based chemoradiotherapy in magnetic resonance imaging (MRI)-defined poor-risk locally advanced low rectal cancer. PATIENTS AND METHODS:This...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-019-07342-7

    authors： Konishi T,Shinozaki E,Murofushi K,Taguchi S,Fukunaga Y,Nagayama S,Fujimoto Y,Akiyoshi T,Nagasaki T,Suenaga M,Chino A,Kawachi H,Yamamoto N,Ishikawa Y,Oguchi M,Ishizuka N,Ueno M,Yamaguchi K

    更新日期：2019-08-01 00:00:00

  • Detection of sentinel node in gastric cancer surgery by indocyanine green fluorescence imaging: comparison with infrared imaging.

    abstract：BACKGROUND:Secure methods for clinical detection of the sentinel node (SN) are in great demand to avoid unnecessary resection. This was a clinical exploration/feasibility study of a novel detection system for SN biopsy using indocyanine green (ICG) fluorescence imaging in gastric cancer surgery. METHODS:SN biopsy usin...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-008-9872-7

    authors： Miyashiro I,Miyoshi N,Hiratsuka M,Kishi K,Yamada T,Ohue M,Ohigashi H,Yano M,Ishikawa O,Imaoka S

    更新日期：2008-06-01 00:00:00

  • Elective Regional Therapy Treatment for Hepatic Adenoma.

    abstract：BACKGROUND:Locoregional therapy treatments for hepatic adenoma (HA) are typically limited to selective hepatic arterial embolization (HAE) to control acute hemorrhage. This systematic review sought to report the utilization of HAE and ablation for non-emergent treatment of HA. METHODS:A PubMed query identified studies...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-018-6802-1

    authors： Silva JP,Klooster B,Tsai S,Christians KK,Clarke CN,Mogal H,Clark Gamblin T

    更新日期：2019-01-01 00:00:00

  • Toward better soft tissue sarcoma staging: building on american joint committee on cancer staging systems versions 6 and 7.

    abstract：BACKGROUND:Based on review of patient data in case conferences over time, we hypothesized that clinically relevant data are omitted in routine soft tissue sarcoma staging. METHODS:We examined subsets of a prospectively collected single institution soft tissue sarcoma database with respect to criteria of the AJCC versi...

    journal_title：Annals of surgical oncology

    pub_type： 临床试验,杂志文章

    doi：10.1245/s10434-013-3052-0

    authors： Maki RG,Moraco N,Antonescu CR,Hameed M,Pinkhasik A,Singer S,Brennan MF

    更新日期：2013-10-01 00:00:00

  • Lymph node metastases in patients undergoing surgery for a gallbladder cancer. Extension of the lymph node dissection and prognostic value of the lymph node ratio.

    abstract：BACKGROUND:Lymph node (LN) status is one of the strongest prognostic factors after gallbladder cancer (GBC) resection. The adequate extension of LN dissection and the stratification of the prognosis in N+ patients have been debated. The present study aims to clarify these issues. METHODS:A total of 112 consecutive pat...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-014-4044-4

    authors： Birnbaum DJ,Viganò L,Russolillo N,Langella S,Ferrero A,Capussotti L

    更新日期：2015-03-01 00:00:00

  • Prognostic value of lymph node yield and metastatic lymph node ratio in medullary thyroid carcinoma.

    abstract：INTRODUCTION:Lymphadenectomy and thyroidectomy is standard treatment for medullary thyroid carcinoma (MTC), but the prognostic importance of the number of lymph nodes removed (lymph node yield, LNY) and the proportion of metastatic lymph nodes resected (metastatic lymph node ratio, MLNR) is unknown. We hypothesized tha...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-008-0022-z

    authors： Leggett MD,Chen SL,Schneider PD,Martinez SR

    更新日期：2008-09-01 00:00:00

  • Association Between Patient Satisfaction and Short-Term Outcomes After Major Cancer Surgery.

    abstract：OBJECTIVE:The aim of this study was to investigate whether patient satisfaction, as measured by the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey, is associated with short-term outcomes after major cancer surgery. MATERIALS AND METHODS:We first used national Medicare claims to identi...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-017-6049-2

    authors： Kaye DR,Richardson CR,Ye Z,Herrel LA,Ellimoottil C,Miller DC

    更新日期：2017-11-01 00:00:00

  • Determining the association between preoperative computed tomography findings and postoperative outcomes after cytoreductive surgery and perioperative intraperitoneal chemotherapy for pseudomyxoma peritonei.

    abstract：BACKGROUND:This study evaluates the accuracy of computed tomography (CT) scoring of the peritoneal cancer index (PCI) and examines its association with surgical morbidity and outcomes in pseudomyxoma peritonei. METHODS:Forty-seven patients with pseudomyxoma peritonei had preoperative evaluation of CT scans and were tr...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-010-1492-3

    authors： Chua TC,Al-Zahrani A,Saxena A,Glenn D,Liauw W,Zhao J,Morris DL

    更新日期：2011-06-01 00:00:00

  • Total Laparoscopic Pancreaticoduodenectomy with Venous Reconstruction for Pancreatic Head Cancer with Involvement of the Superior Mesenteric Vein-Portal Vein Confluence.

    abstract：BACKGROUND:Laparoscopic pancreaticoduodenectomy with venous reconstruction is not commonly performed due to its technical challenges. In this video, we focus on the technical aspects for how to perform this procedure safely. METHODS:In a 69-year-old female with jaundice and diarrhea, a computed tomography scan showed ...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-018-6762-5

    authors： Garbarino GM,Fuks D,Cowan J,Ward M,Moisan F,Donatelli G,Beaussier M,Gayet B

    更新日期：2018-12-01 00:00:00

  • Accurate lymph node staging is of greater prognostic importance than subclassification of the T2 category for gastric adenocarcinoma.

    abstract：BACKGROUND:Examination of 15 or more lymph nodes is necessary for accurate staging of gastric adenocarcinoma. This study examined whether prognostic discrimination is improved by distinguishing between pT2 tumors limited to the muscularis propria (MP) and those extending to subserosa (SS). METHODS:A single-institution...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/aso.2003.09.009

    authors： Sarela AI,Turnbull AD,Coit DG,Klimstra D,Brennan MF,Karpeh MS

    更新日期：2003-08-01 00:00:00

  • The utility of frozen section evaluation for follicular thyroid lesions.

    abstract：BACKGROUND:Because fine-needle aspiration cannot reliably discriminate between benign and malignant follicular thyroid lesions, some surgeons use intraoperative frozen section (FS) to guide operative management. To determine the utility of FS for these lesions, we reviewed our institutional experience. METHODS:Between...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1007/BF02524352

    authors： Callcut RA,Selvaggi SM,Mack E,Ozgul O,Warner T,Chen H

    更新日期：2004-01-01 00:00:00

  • Risk Factors for Positive Deep Pelvic Nodal Involvement in Patients with Palpable Groin Melanoma Metastases: Can the Extent of Surgery be Safely Minimized? : A Retrospective, Multicenter Cohort Study.

    abstract：BACKGROUND:Patients with palpable melanoma groin metastases have a poor prognosis. There is debate whether a combined superficial and deep groin dissection (CGD) is necessary or if superficial groin dissection (SGD) alone is sufficient. AIM:The aim of this study was to analyze risk factors for deep pelvic nodal involv...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,多中心研究

    doi：10.1245/s10434-015-4602-4

    authors： Oude Ophuis CM,van Akkooi AC,Hoekstra HJ,Bonenkamp JJ,van Wissen J,Niebling MG,de Wilt JH,van der Hiel B,van de Wiel B,Koljenović S,Grünhagen DJ,Verhoef C

    更新日期：2015-12-01 00:00:00

  • Iliosacral resections of pelvic malignant tumors and reconstruction with nonvascular bilateral fibular autografts.

    abstract：BACKGROUND:Iliosacral resection of pelvic malignant tumors and subsequent reconstruction have tested the ingenuity of orthopedic oncologists because of the difficulty of oncological wide resection and the complex biomechanics of the sacroiliac joint render reconstruction challenging. This study compared the functional ...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-012-2339-x

    authors： Wang J,Tang Q,Xie X,Yin J,Zhao Z,Li Z,Zou C,Huang G,Shen J

    更新日期：2012-12-01 00:00:00

  • Results of a Phase Ib Trial of Combination Immunotherapy with a CD8+ T Cell Eliciting Vaccine and Trastuzumab in Breast Cancer Patients.

    abstract：BACKGROUND:CD8+ T cell-eliciting vaccines are being investigated in breast cancer patients. Preclinical data showed that trastuzumab increases the susceptibility of tumor cells to lysis by vaccine-generated CD8+ T cells, suggesting potential benefit of a combination immunotherapy strategy. The current trial was underta...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-017-5844-0

    authors： Clifton GT,Litton JK,Arrington K,Ponniah S,Ibrahim NK,Gall V,Alatrash G,Peoples GE,Mittendorf EA

    更新日期：2017-08-01 00:00:00

  • Retrospective evaluation of the influence of postoperative tumor marker status on survival and patterns of recurrence after surgery for pancreatic cancer based on RECIST guidelines.

    abstract：PURPOSE:The purpose of this study was to obtain a comprehensive understanding of the impact of postoperative tumor marker (TM) normalization on survival after pancreatectomy for pancreatic carcinoma. We propose the concept of surgical RECIST based on residual tumor and TM status. METHODS:A total of consecutive patient...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-010-1311-x

    authors： Motoi F,Rikiyama T,Katayose Y,Egawa S,Unno M

    更新日期：2011-02-01 00:00:00

  • Toxicity of Immune Checkpoint Inhibitors: Considerations for the Surgeon.

    abstract：BACKGROUND:The use of immunotherapeutic agents, specifically immune checkpoint inhibitors (ICIs) for solid malignancies, is rapidly rising, and many new agents and treatment combinations are in development. However, ICIs have a unique side-effect profile of immune-related adverse events (irAEs) compared with chemothera...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,评审

    doi：10.1245/s10434-019-08183-0

    authors： Helmink BA,Roland CL,Kiernan CM,Wargo JA

    更新日期：2020-05-01 00:00:00

  • Laparoscopic bowel resection in the setting of metastatic colorectal cancer.

    abstract：BACKGROUND:This study aimed to review the outcomes of laparoscopic colorectal resection for patients with stage IV colorectal cancer. METHODS:From the prospectively collected database for patients who underwent surgery for colorectal cancer in our institution, those with stage IV colorectal cancer who underwent electi...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-008-9820-6

    authors： Law WL,Fan JK,Poon JT,Choi H,Lo OS

    更新日期：2008-05-01 00:00:00