Results of a Phase Ib Trial of Combination Immunotherapy with a CD8+ T Cell Eliciting Vaccine and Trastuzumab in Breast Cancer Patients.

abstract：BACKGROUND:Laparoscopic versus open hepatocellular carcinoma (HCC) resection reduces morbidity without a compromise in oncologic safety.1-4 Moreover, in the subgroup of cirrhotic patients, a decreased risk of prolonged postoperative ascites and liver decompensation has been reported.5-7 METHODS: A 54-year-old homeless,...

journal_title：Annals of surgical oncology

authors： Vega EA,Nicolaescu DC,Salehi O,Kozyreva O,Vellayappan U,Ricklan D,McCarty J,Fontan F,Pomposelli F,Conrad C

更新日期：2020-04-01 00:00:00

abstract：PURPOSE:Pathologic downstaging following chemotherapy for stage III-N2 NSCLC is a well-known positive prognostic indicator. However, the predictive factors for locoregional recurrence (LRR) in these patients are largely unknown. METHODS:Between 1998 and 2008, 153 patients with clinically or pathologically staged III-N...

journal_title：Annals of surgical oncology

authors： Amini A,Lou F,Correa AM,Baldassarre R,Rimner A,Huang J,Roth JA,Swisher SG,Vaporciyan AA,Lin SH

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:The heterogeneous nuclear ribonucleoprotein (hnRNP) K is an essential RNA and DNA binding protein involved in gene expression and signal transduction. The role of hnRNP K in cancer is relatively understudied. However, several cellular functions strongly indicate that hnRNP K is involved in tumorigenesis. Onc...

journal_title：Annals of surgical oncology

authors： Wen F,Shen A,Shanas R,Bhattacharyya A,Lian F,Hostetter G,Shi J

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Sentinel lymph node biopsy (SLNB) is associated with reduced morbidity, although lymphedema remains a significant complication. Previously, we found no association between number of excised lymph nodes (LNs) and measured lymphedema in SLNB patients. In this analysis, we examined the relationship between numb...

journal_title：Annals of surgical oncology

authors： Goldberg JI,Riedel ER,Morrow M,Van Zee KJ

更新日期：2011-10-01 00:00:00

abstract：INTRODUCTION:Regional nodal status is the most powerful predictor of recurrence and survival in women with breast cancer. Lymphatic mapping and sentinel lymph node (SLN) biopsy have been found to accurately predict the regional nodal status. Preoperative lymphoscintigraphy has been used in melanoma patients to identify...

journal_title：Annals of surgical oncology

authors： Dupont EL,Kamath VJ,Ramnath EM,Shivers SC,Cox C,Berman C,Leight GS Jr,Ross MI,Blumencranz P,Reintgen DS,DOD Breast Lymphatic Mapping Trial Investigators.

更新日期：2001-05-01 00:00:00

abstract：INTRODUCTION:Obesity adds to the technical difficulty of colorectal surgery and is a risk factor for postoperative complications. We hypothesized that obese patients have increased morbidity and poor oncologic outcomes after proctectomy for rectal adenocarcinoma. METHODS:Adult patients undergoing total mesorectal exci...

journal_title：Annals of surgical oncology

authors： Ballian N,Yamane B,Leverson G,Harms B,Heise CP,Foley EF,Kennedy GD

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Malignant pleural effusions are seen frequently in clinical practice and are most commonly caused by breast cancer and lung cancer. Standard treatment usually consists of complete drainage of the pleural space via a chest tube and instillation of a pleural irritant to obtain pleural symphysis. In a majority ...

journal_title：Annals of surgical oncology

authors： Fry WA,Khandekar JD

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Health care reform places primary care (PC) physicians in an increasingly significant role for breast cancer screening and diagnosis. This study assessed the adequacy of traditional PC resident training to prepare physicians for this front-line role. METHODS:Sixty-eight primary care residents, representing ...

journal_title：Annals of surgical oncology

authors： Chalabian J,Formenti S,Russell C,Pearce J,Dunnington G

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Pancreatic adenocarcinoma is among the most resistant of human cancers, yet specific mechanisms of treatment resistance remain poorly understood. Models to study pancreatic cancer resistance remain limited and should reflect in vivo changes that occur within patient tumors. We sought to identify consistent, ...

journal_title：Annals of surgical oncology

authors： Kim MP,Truty MJ,Choi W,Kang Y,Chopin-Lally X,Gallick GE,Wang H,McConkey DJ,Hwang R,Logsdon C,Abbruzzesse J,Fleming JB

更新日期：2012-07-01 00:00:00

abstract：:Breast surgery has evolved as a subspecialty of general surgery and requires a working knowledge of benign and malignant diseases, surgical techniques, shared decision-making with patients, collaboration with a multi-disciplinary team, and a basic foundation in surgical ethics. Ethics is defined as the practice of ana...

journal_title：Annals of surgical oncology

authors： Throckmorton A,VanderWalde L,Brackett C,Dominici L,Eisenhauer T,Johnson N,Kong A,Ludwig K,O'Neill J,Pugliese M,Teller P,Sarantou T

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Transarterial chemoembolization (TACE) is often utilized for patients with inoperable neuroendocrine carcinoma liver metastases. Often, metastatic disease is not limited to the liver. The impact of extrahepatic disease (EHD) on outcomes and response after TACE has not been described. METHODS:We reviewed 192...

journal_title：Annals of surgical oncology

authors： Arrese D,McNally ME,Chokshi R,Feria-Arias E,Schmidt C,Klemanski D,Gregory G,Khabiri H,Shah M,Bloomston M

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:As increased focus is placed on quality of care in surgery, readmission is an increasingly important metric by which hospital and surgeon quality is measured. For complex pancreatic surgery, we hypothesized that increased pancreaticoduodenectomy (PD) volume may mitigate readmission rates. METHODS:The Univer...

journal_title：Annals of surgical oncology

authors： Sutton JM,Wilson GC,Wima K,Hoehn RS,Cutler Quillin R 3rd,Hanseman DJ,Paquette IM,Sussman JJ,Ahmad SA,Shah SA,Abbott DE

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:We hypothesized that metastasis beyond the sentinel lymph nodes (SLN) to the nonsentinel nodes (NSN) is an important predictor of survival. MATERIALS AND METHODS:Analysis was performed of a prospective multi-institutional study that included patients with melanoma ≥ 1.0 mm in Breslow thickness. All patients...

journal_title：Annals of surgical oncology

authors： Brown RE,Ross MI,Edwards MJ,Noyes RD,Reintgen DS,Hagendoorn LJ,Stromberg AJ,Martin RC,McMasters KM,Scoggins CR

更新日期：2010-12-01 00:00:00

abstract：:Triple-negative breast cancer (TNBC) is an operational term that refers to a heterogeneous collection of breast cancers lacking expression of estrogen receptor (ER), progesterone receptor, and HER2. These tumors account for 12-17 % of all breast cancers, preferentially affect young women, are more frequent in women of...

journal_title：Annals of surgical oncology

authors： Newman LA,Reis-Filho JS,Morrow M,Carey LA,King TA

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Breast conservation therapy (BCT) and adjuvant hormonal therapy for estrogen-receptor positive breast cancers have become standard of care. Our objectives were to evaluate trends in the surgical management and adjuvant therapy for early-stage breast cancer and to identify factors predicting survival. METHOD...

journal_title：Annals of surgical oncology

authors： Kennedy T,Stewart AK,Bilimoria KY,Patel-Parekh L,Sener SF,Winchester DP

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:The enhanced esthetics and demonstrated oncologic safety of nipple-sparing mastectomy (NSM) in selected patients have resulted in increased rates among patients with locally advanced breast cancer and/or additional risk factors (obesity, prior radiation, surgery). Limited data exist on complication and recon...

journal_title：Annals of surgical oncology

authors： Young WA,Degnim AC,Hoskin TL,Jakub JW,Nguyen MD,Tran NV,Harless CA,Manrique OJ,Boughey JC,Hieken TJ

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Extension of lymphadenectomy in gastric cancer is controversial, and preoperative diagnosis of lymph node metastases (LNM) is difficult. Therefore, knowledge-based systems such as the Maruyama computer program (MCP) are being developed. MCP shows good prognostic value for the compartments; however, for diffe...

journal_title：Annals of surgical oncology

authors： Bollschweiler EH,Mönig SP,Hensler K,Baldus SE,Maruyama K,Hölscher AH

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Cancer registries have been set up worldwide to provide information for cancer health planning. There are known variations in breast cancer incidence and mortality worldwide. However, breast cancer incidence, pathological characteristics, and survival data is still under-reported in Asian countries. This is ...

journal_title：Annals of surgical oncology

authors： Kwong A,Mang OW,Wong CH,Chau WW,Law SC,Hong Kong Breast Cancer Research Group.

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:Treatment of synovial sarcoma (SS) is challenging because of its unpredictable clinical behavior. We reviewed our institutional experience with pediatric SS to identify prognostic indicators and survival outcomes. METHODS:We retrospectively reviewed all pediatric/adolescent patients (age<22 years) with confirm...

journal_title：Annals of surgical oncology

authors： Stanelle EJ,Christison-Lagay ER,Healey JH,Singer S,Meyers PA,La Quaglia MP

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Although the American Joint Committee on Cancer (AJCC) classification is the most accepted lymph node (LN) staging system for gallbladder adenocarcinoma (GBA), other LN prognostic schemes have been proposed. This study sought to define the performance of the AJCC LN staging system relative to the number of m...

journal_title：Annals of surgical oncology

authors： Amini N,Kim Y,Wilson A,Margonis GA,Ethun CG,Poultsides G,Tran T,Idrees K,Isom CA,Fields RC,Krasnick B,Weber SM,Salem A,Martin RC,Scoggins C,Shen P,Mogal HD,Schmidt C,Beal E,Hatzaras I,Shenoy R,Maithel SK,Pawli

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The inability to visualize the patient and surgical site directly, limits the use of current near infrared fluorescence-guided surgery systems for real-time sentinel lymph node biopsy and tumor margin assessment. METHODS:We evaluated an optical see-through goggle augmented imaging and navigation system (GAI...

journal_title：Annals of surgical oncology

authors： Mondal SB,Gao S,Zhu N,Habimana-Griffin L,Akers WJ,Liang R,Gruev V,Margenthaler J,Achilefu S

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:There is no consensus on the selection criteria for ovarian preservation in cervical cancer, and the role of neoadjuvant chemotherapy (NACT) on ovarian metastasis (OM) is also unknown. METHODS:A total of 1,889 cervical cancer patients with International Federation of Gynecology and Obstetrics (FIGO) stages ...

journal_title：Annals of surgical oncology

authors： Hu T,Wu L,Xing H,Yang R,Li X,Huang K,Jia Y,Zhang Q,Chen Z,Wang S,Liu D,Han X,Lin Z,Qu P,Cai H,Song X,Tian X,Wang H,Wang S,Xie X,Li S,Ma D

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Pseudoangiomatous stromal hyperplasia (PASH) is a benign localized fibrotic lesion in which clusters of spindle cells form cleftlike spaces, resembling ectatic vessels. Its relationship to breast cancer risk has not been characterized. MATERIALS AND METHODS:Histological presence of PASH was evaluated by rev...

journal_title：Annals of surgical oncology

authors： Degnim AC,Frost MH,Radisky DC,Anderson SS,Vierkant RA,Boughey JC,Pankratz VS,Ghosh K,Hartmann LC,Visscher DW

更新日期：2010-12-01 00:00:00

abstract：PURPOSE:The volume of surgical procedures performed by hospitals and surgeons has a strong influence on outcomes for a number of surgeries. We examined the influence of surgeon and hospital case volume on morbidity, mortality, and resource utilization for women with endometrial cancer undergoing laparoscopic hysterecto...

journal_title：Annals of surgical oncology

authors： Wright JD,Hershman DL,Burke WM,Lu YS,Neugut AI,Lewin SN,Herzog TJ

更新日期：2012-03-01 00:00:00

abstract：INTRODUCTION:Sentinel lymph node mapping (SLNM) with multilevel sections (MLS) and cytokeratin immunohistochemistry (CK-IHC) of sentinel lymph nodes (SLNs) upstages 15-20% of patients (pts). False-positive SLNs occur in breast cancer due to mechanical transport of cells during mapping procedures, or to pre-existing ben...

journal_title：Annals of surgical oncology

authors： Wiese D,Saha S,Yestrepsky B,Korant A,Sirop S

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Persistent post-mastectomy pain (PPMP) is a significant negative outcome occurring after breast surgery, and understanding which individual women are most at risk is essential to targeting of preventive efforts. The biopsychosocial model of pain suggests that factors from many domains may importantly modulat...

journal_title：Annals of surgical oncology

authors： Schreiber KL,Zinboonyahgoon N,Flowers KM,Hruschak V,Fields KG,Patton ME,Schwartz E,Azizoddin D,Soens M,King T,Partridge A,Pusic A,Golshan M,Edwards RR

更新日期：2021-01-15 00:00:00

abstract：BACKGROUND:There are many theoretical advantages that a minimally invasive approach to the pancreaticoduodenectomy might offer patients with benign and malignant disease of the head of the pancreas over traditional open techniques, including improved recovery time, decreased hospital stay, and earlier initiation of and...

journal_title：Annals of surgical oncology

authors： Zeh HJ,Zureikat AH,Secrest A,Dauoudi M,Bartlett D,Moser AJ

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Esophageal cancer frequently metastasizes to lymph nodes along the recurrent laryngeal nerve (RLN),1 therefore it is essential to dissect RLN nodes for curative esophagectomy.2 Right-sided aortic arch (RAA), a rare congenital anomaly, occurs in approximately 0.1% of adults.3 Because RAA forms a vascular ring...

journal_title：Annals of surgical oncology

authors： Okamura A,Watanabe M,Yuda M,Shoji Y,Yamashita K,Hayami M,Imamura Y,Mine S

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:The delta-shaped gastroduodenostomy, an intracorporeal Billroth-I anastomosis after laparoscopic distal gastrectomy and using only endoscopic linear staplers, has been increasingly adopted by gastrointestinal surgeons.1 (-) 5 We modified this technique to simplify operation procedures and reduce surgical tra...

journal_title：Annals of surgical oncology

authors： Huang C,Lin M,Chen Q,Lin J,Zheng C,Li P,Xie J,Wang J,Lu J,Chen T,Yang X

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Poly(ADP-ribose) polymerase (PARP) is an important regulator of programmed cell death in response to alkylating agents such as temozolomide (TMZ). The goal of this study was to determine if a systemically administered PARP-inhibitor (INO-1001) could augment the efficacy of TMZ in a rat model of extremity mal...

journal_title：Annals of surgical oncology

authors： Toshimitsu H,Yoshimoto Y,Augustine CK,Padussis JC,Yoo JS,Angelica Selim M,Pruitt SK,Friedman HS,Ali-Osman F,Tyler DS

更新日期：2010-08-01 00:00:00