Inhibition of poly(ADP-ribose) polymerase enhances the effect of chemotherapy in an animal model of regional therapy for the treatment of advanced extremity malignant melanoma.

abstract：BACKGROUND:An oncolytic herpes simplex virus type 1 mutant (HF10) has been isolated and evaluated for antitumor efficacy in a syngeneic immunocompetent mouse model, where it was effective against cancer and conferred resistance to rechallenge with tumor cells in all surviving mice. Several studies have shown that HF10 ...

journal_title：Annals of surgical oncology

authors： Kimata H,Imai T,Kikumori T,Teshigahara O,Nagasaka T,Goshima F,Nishiyama Y,Nakao A

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to investigate the diagnostic and prognostic value of circulating endothelial cell (CEC), a potential surrogate of tumor angiogenesis, in malignant pleural mesothelioma (MPM). METHODS:We prospectively evaluated CEC count in 4.0 mL of peripheral blood sampled from patients with ...

journal_title：Annals of surgical oncology

authors： Yoneda K,Tanaka F,Kondo N,Orui H,Hashimoto M,Takuwa T,Matsumoto S,Okumura Y,Tsubota N,Sato A,Tsujimura T,Kuribayashi K,Fukuoka K,Nakano T,Hasegawa S

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Malignant ascites (MA) is a distressing problem usually managed by repeated paracenteses. Paracentesis represents a meaningful time point in identifying patients with a specific presentation. OBJECTIVE:The objective of this study is to examine symptom clustering in MA patients at paracentesis. METHODS:Pre-...

journal_title：Annals of surgical oncology

authors： Husain A,Bezjak A,Easson A

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Seroma is a frequent problem after mastectomy (ME) and axillary lymph node dissection (ALND). Seroma is associated with pain, discomfort, impaired mobilisation and repeated aspirations, often resulting in a surgical site infection (SSI). It has already been demonstrated that minimizing dead space through fix...

journal_title：Annals of surgical oncology

authors： ten Wolde B,van den Wildenberg FJ,Keemers-Gels ME,Polat F,Strobbe LJ

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Metastatic breast cancer is an aggressive disease associated with recurrence and decreased survival. To improve outcomes and develop more effective treatment strategies for patients with breast cancer, it is important to understand the molecular mechanisms underlying metastasis. METHODS:We used allelic imba...

journal_title：Annals of surgical oncology

authors： Becker TE,Ellsworth RE,Deyarmin B,Patney HL,Jordan RM,Hooke JA,Shriver CD,Ellsworth DL

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Endoscopic resection (ER) is an effective treatment for early gastric cancer (EGC) without lymph node metastasis. However, after ER additional surgery may be needed to manage the risks presented by residual cancer or lymph node metastasis. METHODS:ER was performed on 344 gastric adenocarcinomas between Nove...

journal_title：Annals of surgical oncology

authors： Ryu KW,Choi IJ,Doh YW,Kook MC,Kim CG,Park HJ,Lee JH,Lee JS,Lee JY,Kim YW,Bae JM

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Axillary nodal status is the most important prognostic factor for patients with breast cancer. Clinical assessment and imaging modalities are not always reliable. Surgical removal and histopathological examination of axillary lymph nodes remain essential methods of staging the axilla. However, the optimal ma...

journal_title：Annals of surgical oncology

authors： Samphao S,Eremin JM,El-Sheemy M,Eremin O

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Patients with locally advanced rectal cancer may present with synchronous distant metastases. Choice of optimal treatment--neoadjuvant chemoradiation versus systemic chemotherapy alone--depends on accurate assessment of distant disease. We prospectively evaluated the ability of [18F]fluorodeoxyglucose ([18F]...

journal_title：Annals of surgical oncology

authors： Nahas CS,Akhurst T,Yeung H,Leibold T,Riedel E,Markowitz AJ,Minsky BD,Paty PB,Weiser MR,Temple LK,Wong WD,Larson SM,Guillem JG

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:American College of Surgeons Oncology Group Z0011 confirms the safety of omitting axillary lymph node dissection (ALND) and regional nodal irradiation (RNI) in breast cancer patients with one to two positive sentinel lymph nodes (SLNs), without compromising disease-free survival (DFS) and overall survival (O...

journal_title：Annals of surgical oncology

authors： Raber BM,Lin H,Shen Y,Shaitelman SF,Bedrosian I

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The interval between preoperative chemoradiotherapy and surgery reportedly affects perioperative outcomes and survival; however, the optimal interval in esophageal cancer patients remains uncertain. OBJECTIVE:Our aim was to determine whether a prolonged interval between preoperative neoadjuvant chemoradioth...

journal_title：Annals of surgical oncology

authors： Wakita A,Motoyama S,Sato Y,Nagaki Y,Fujita H,Terata K,Imai K,Minamiya Y

更新日期：2020-10-13 00:00:00

abstract：PURPOSE:To determine the risk factors related to adnexal involvement in endometrial cancer (EC) and its implications for ovarian preservation in young women. METHODS:We analyzed a series of 802 patients who were treated at AC Camargo Cancer Center from July 1991 to July 2017. Patients who had peritoneal or systemic di...

journal_title：Annals of surgical oncology

authors： Baiocchi G,Clemente AG,Mantoan H,da Costa WL Jr,Bovolim G,Guimaraes APG,da Costa AABA,De Brot L,Faloppa CC

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Visceral fat accumulation and muscle depletion have been identified as poor prognostic factors for various cancers. However, the significance of visceral adiposity and sarcopenic visceral obesity on outcomes after resection of pancreatic cancer remains unclear. METHODS:A retrospective analysis of 301 patien...

journal_title：Annals of surgical oncology

authors： Okumura S,Kaido T,Hamaguchi Y,Kobayashi A,Shirai H,Yao S,Yagi S,Kamo N,Hatano E,Okajima H,Takaori K,Uemoto S

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Early gastric cancer that meets the expanded criteria for endoscopic resection (ER) is expected to be associated with a negligible risk for lymph node metastasis (LNM); however, recent studies have reported LNM in submucosal gastric cancer patients who met the existing criteria. In this study, we develop the...

journal_title：Annals of surgical oncology

authors： Ma DW,Lee SJ,Kook MC,Park DY,Ahn S,Ryu KW,Choi IJ,Noh SH,Kim H,Lee YC,Kim JH

更新日期：2020-03-01 00:00:00

abstract：INTRODUCTION:The rate of contralateral prophylactic mastectomy (CPM) has recently increased. The aim of this study is to assess perceptions of contralateral breast cancer (CBC) risk among breast cancer patients and to evaluate tumor and patient factors associated with risk perception. METHODS:We conducted a prospectiv...

journal_title：Annals of surgical oncology

authors： Abbott A,Rueth N,Pappas-Varco S,Kuntz K,Kerr E,Tuttle T

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Detection of cancer micrometastases is required for improvement of cancer therapy. The aim of this study was to establish a rapid and practical genetic assay to detect micrometastasis in gastric cancer and to assess its clinical significance with respect to prognosis. METHODS:A novel RNA amplification syste...

journal_title：Annals of surgical oncology

authors： Ishii T,Fujiwara Y,Ohnaka S,Hayashi T,Taniguchi H,Takiguchi S,Yasuda T,Yano M,Monden M

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Intraoperative ultrasound (IOUS)-guided lumpectomy in early breast cancer has shown advantages over other techniques. However, the use of IOUS has been less explored after neoadjuvant treatment (NAT). This study aimed to compare IOUS- and wire localization (WL)-guided surgery in breast cancer patients after ...

journal_title：Annals of surgical oncology

authors： Rubio IT,Esgueva-Colmenarejo A,Espinosa-Bravo M,Salazar JP,Miranda I,Peg V

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:A positive circumferential radial margin (CRM) after rectal cancer surgery is an important predictor of local recurrence. The definition of a positive CRM differs internationally, and reported rates vary greatly in the literature. This study used time-series population-based data to assess positive CRM rates...

journal_title：Annals of surgical oncology

authors： Keng C,Coates A,Grubac V,Lovrics P,DeNardi F,Thabane L,Simunovic M

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Age of patients with melanoma varies directly with mortality and inversely with the presence of sentinel lymph node (SLN) metastasis. To gain further insight into this apparent paradox, we analyzed the relationship between age and other major prognostic factors. METHODS:The Sunbelt Melanoma Trial is a prosp...

journal_title：Annals of surgical oncology

authors： Chao C,Martin RC 2nd,Ross MI,Reintgen DS,Edwards MJ,Noyes RD,Hagendoorn LJ,Stromberg AJ,McMasters KM

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Patients undergoing cytoreductive surgery for colorectal peritoneal metastases who have a pathologic complete response (pCR) to neoadjuvant chemotherapy experience a significantly longer survival than those with residual disease. This response is known only after surgery. This study aimed to examine clinical...

journal_title：Annals of surgical oncology

authors： Bhatt A,Rousset P,Benzerdjeb N,Kammar P,Mehta S,Parikh L,Goswami G,Shaikh S,Kepenekian V,Passot G,Glehen O

更新日期：2020-11-18 00:00:00

abstract：:Breast surgery has evolved as a subspecialty of general surgery and requires a working knowledge of benign and malignant diseases, surgical techniques, shared decision-making with patients, collaboration with a multi-disciplinary team, and a basic foundation in surgical ethics. Ethics is defined as the practice of ana...

journal_title：Annals of surgical oncology

authors： Throckmorton A,VanderWalde L,Brackett C,Dominici L,Eisenhauer T,Johnson N,Kong A,Ludwig K,O'Neill J,Pugliese M,Teller P,Sarantou T

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Glioma recurrence usually occurs close to the tumor resection margins as a result of residual infiltrating glioma cells. 5-aminolevulinic acid (ALA) fluorescence-guided resection of gliomas has been demonstrated to enhance discrimination of tumor tissue and to improve survival. ALA-based photodynamic therapy...

journal_title：Annals of surgical oncology

authors： Zhao SG,Chen XF,Wang LG,Yang G,Han DY,Teng L,Yang MC,Wang DY,Shi C,Liu YH,Zheng BJ,Shi CB,Gao X,Rainov NG

更新日期：2013-12-01 00:00:00

abstract：:Preoperative needle diagnosis (PND) is being considered as a quality measure in breast cancer surgery. This criterion has not been thoroughly evaluated in the literature. The purpose of this study is to assess ease of access to these data and rate of compliance in a tertiary care center. We retrospectively reviewed al...

journal_title：Annals of surgical oncology

authors： Pocock B,Taback B,Klein L,Joseph KA,El-Tamer M

更新日期：2009-05-01 00:00:00

abstract：PURPOSE:An increasing proportion of breast cancer patients undergo contralateral prophylactic mastectomy (CPM) to reduce their risk of contralateral breast cancer (CBC). Our goal was to evaluate CBC risk perception changes over time among breast cancer patients. METHODS:We conducted a prospective, longitudinal study o...

journal_title：Annals of surgical oncology

authors： Portschy PR,Abbott AM,Burke EE,Nzara R,Marmor S,Kuntz KM,Tuttle TM

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:The quality of decision-making in cancer multidisciplinary team (MDT) meetings is variable, which can result in suboptimal clinical decision making. We developed MDT-QuIC, an evidence-based tool to support clinical decision making by MDTs, which was evaluated by key users. METHODS:Following a literature rev...

journal_title：Annals of surgical oncology

authors： Lamb BW,Sevdalis N,Vincent C,Green JS

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:The effectiveness of perioperative adjuvant chemotherapy for colorectal cancer liver metastasis (CRLM) remains a matter of debate. Despite the lack of clear evidence supporting its effectiveness after curative hepatectomy, adjuvant chemotherapy has been widely used clinically. The purpose of this study was t...

journal_title：Annals of surgical oncology

authors： Hirokawa F,Hayashi M,Miyamoto Y,Asakuma M,Shimizu T,Komeda K,Inoue Y,Uchiyama K

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:18-F-fluorodeoxyglucose positron emission tomography (FDG-PET) is valuable in staging of esophageal cancer. However, FDG-PET may falsely upstage patients leading to incorrect exclusion from surgical treatment. This study was performed to determine the false-positive rate and possible causes. METHODS:The rat...

journal_title：Annals of surgical oncology

authors： van Westreenen HL,Heeren PA,Jager PL,van Dullemen HM,Groen H,Plukker JT

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:In breast cancer treatment, intraoperative sentinel lymph node (SLN) evaluation is used to identify patients who may potentially benefit from immediate completion of axillary lymph node dissection. METHODS:Prospectively collected breast cancer registry data identified 516 SLN biopsies between January 2003 a...

journal_title：Annals of surgical oncology

authors： Pugliese MS,Tickman R,Wang NP,Atwood M,Beatty JD

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Recently, ultrasound (US)-guided needle biopsy has been proposed as an acceptable alternative to open biopsy in women with nonpalpable breast masses. This study evaluated the accuracy of US-guided needle biopsy of nonpalpable breast masses performed by surgeons at the time of the initial clinical examination...

journal_title：Annals of surgical oncology

authors： Staren ED

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:The impact of cardiorespiratory comorbidity on operative outcomes after esophagectomy remains controversial. This study investigated the effect of cardiorespiratory comorbidity on postoperative complications for patients treated for esophageal or gastroesophageal junction cancer. PATIENTS AND METHODS:A Euro...

journal_title：Annals of surgical oncology

authors： Klevebro F,Elliott JA,Slaman A,Vermeulen BD,Kamiya S,Rosman C,Gisbertz SS,Boshier PR,Reynolds JV,Rouvelas I,Hanna GB,van Berge Henegouwen MI,Markar SR

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Gastrointestinal leak (GIL) after cytoreductive surgery with heated intraperitoneal chemotherapy (CRS/HIPEC) is associated with significant morbidity and mortality. This study aimed to identify GIL prognostic factors and its impact on overall survival. METHODS:A retrospective analysis of a prospectively mai...

journal_title：Annals of surgical oncology

authors： Chouliaras K,Levine EA,Fino N,Shen P,Votanopoulos KI

更新日期：2017-04-01 00:00:00