Increased expression of ABCB6 enhances protoporphyrin IX accumulation and photodynamic effect in human glioma.

abstract：BACKGROUND:Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) is standard treatment for peritoneal dissemination from appendiceal cancer (AC); however, its role in high-grade histopathologic subtypes (high-grade mucinous carcinoma peritonei [HGMCP] and HGMCP with signet ring cells [HGMCP-S]...

journal_title：Annals of surgical oncology

authors： Munoz-Zuluaga C,Sardi A,King MC,Nieroda C,Sittig M,MacDonald R,Gushchin V

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Despite data from randomized trials supporting omission of radiation therapy (RT) for women ≥ 70 years of age with T1, estrogen receptor-positive (ER+) tumors undergoing breast-conserving therapy (BCT), RT usage remains high. We reviewed our institutional experience to determine if risk factors for local rec...

journal_title：Annals of surgical oncology

authors： Downs-Canner S,Zabor EC,Wind T,Cobovic A,McCormick B,Morrow M,Heerdt A

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Brain metastases account for 20-54% of reported deaths from melanoma. Duration and quality of survival depend on the extent of metastatic disease and response to treatment. Treatment goals are palliation of symptoms and prolongation of life. No studies have directly compared surgery alone and surgery with ad...

journal_title：Annals of surgical oncology

authors： Skibber JM,Soong SJ,Austin L,Balch CM,Sawaya RE

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Nipple-sparing mastectomy (NSM) for both risk reduction and cancer is increasing. In the cancer setting, most studies suggest the use of both clinical and intraoperative biopsy criteria in patient selection. This study examines the use of both biopsy and clinical criteria in women undergoing total nipple-rem...

journal_title：Annals of surgical oncology

authors： Stolier A,Stone JC,Moroz K,Hanemann CW,McNabb L,Jones SD,Lacey M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The management of breast cancer (BC) skin metastases represents a therapeutic challenge. Electrochemotherapy (ECT) combines the administration of bleomycin with temporary permeabilization induced by locally administered electric pulses. Preliminary experience with ECT in BC patients is encouraging. METHODS:...

journal_title：Annals of surgical oncology

authors： Cabula C,Campana LG,Grilz G,Galuppo S,Bussone R,De Meo L,Bonadies A,Curatolo P,De Laurentiis M,Renne M,Valpione S,Fabrizio T,Solari N,Guida M,Santoriello A,D'Aiuto M,Agresti R

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The anti-tumor effects of three mouse mammary tumors transfected to express interleukin (IL) 2 or 4 were evaluated. METHODS:Three immunologically different tumors were used: DA3, EMT6, and 410. All three cell lines were successfully transfected using high efficiency viral vectors. Wild-type or transfected t...

journal_title：Annals of surgical oncology

authors： Matory YL,Chen M,Goedegebuure PS,Eberlein TJ

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Lymphadenectomy is important in the surgical treatment of apparent early epithelial ovarian cancers (eEOC); however, its extent is not well defined. We evaluated the role of systematic lymphadenectomy, the risk factors related with lymph node metastases, the implications, and the morbidity of comprehensive s...

journal_title：Annals of surgical oncology

authors： Ditto A,Martinelli F,Reato C,Kusamura S,Solima E,Fontanelli R,Haeusler E,Raspagliesi F

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Preliminary data indicate that tyrosine kinase inhibitors (TKIs) function through rearranged during transfection (RET) in breast cancer. However, TKIs are not specific and can block several receptor tyrosine kinases (RTKs). This study used cell lines and primary breast cancer specimens to determine factors a...

journal_title：Annals of surgical oncology

authors： Spanheimer PM,Lorenzen AW,De Andrade JP,Kulak MV,Carr JC,Woodfield GW,Sugg SL,Weigel RJ

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The transcription factor NF-E2-related factor 2 (Nrf2) was originally identified to be a critical regulator of intracellular antioxidants and phase II detoxification enzymes. Recent studies have shown that high Nrf2 expression gives cancer cells an advantage for survival from anticancer chemotherapy and radi...

journal_title：Annals of surgical oncology

authors： Kawasaki Y,Okumura H,Uchikado Y,Kita Y,Sasaki K,Owaki T,Ishigami S,Natsugoe S

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:The increasing use of mammography has led to a significant increase in the detection of clinically occult lesions, the majority of which prove to be benign. SFNB has been suggested as a means of expediting a diagnosis for lesions that are malignant while limiting surgical biopsies for those that are benign. ...

journal_title：Annals of surgical oncology

authors： Mitnick JS,Vazquez MF,Pressman PI,Harris MN,Roses DF

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:This study aimed to investigate changes in treatment strategy and outcome for patients with primary retroperitoneal sarcoma (RPS) undergoing resection at referral centers during a recent period. METHODS:The study enrolled consecutive adult patients with primary non-metastatic RPS who underwent resection wit...

journal_title：Annals of surgical oncology

authors： Callegaro D,Raut CP,Ng D,Strauss DC,Honoré C,Stoeckle E,Bonvalot S,Haas RL,Vassos N,Conti L,Gladdy RA,Fairweather M,van Houdt W,Schrage Y,van Coevorden F,Rutkowski P,Miceli R,Gronchi A,Swallow CJ

更新日期：2020-10-18 00:00:00

abstract：BACKGROUND:Surgery for locally advanced rectal cancers beyond the plane of total mesorectal excision (TME) or extramesorectal nodal involvement should include complete resection. This study evaluated the oncologic feasibility and safety of robot-assisted surgery for rectal cancer beyond the TME plane. METHODS:The stud...

journal_title：Annals of surgical oncology

authors： Shin US,Nancy You Y,Nguyen AT,Bednarski BK,Messick C,Maru DM,Dean EM,Nguyen ST,Hu CY,Chang GJ

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:The efficacy, toxicity, and patterns of failure of esophageal squamous cell carcinoma (ESCC) treated with selective lymph node (SLN) conventional fraction radiotherapy (CFRT) and S-1 plus cisplatin (CDDP) were evaluated. PATIENTS AND METHODS:67 Patients with clinical stage II-IVa ESCC were enrolled. The tot...

journal_title：Annals of surgical oncology

authors： Wang X,Liu X,Li D,Wang X,Huang W,Li B

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:Unilateral mastectomy (UM) and contralateral prophylactic mastectomy (CPM) for early-stage breast cancer (ESBC) have been increasing. Numerous etiological factors for this rise have been suggested, including increasing use of magnetic resonance imaging (MRI) and reconstruction, surgeon's preference, and patient...

journal_title：Annals of surgical oncology

authors： Covelli AM,Baxter NN,Fitch MI,Wright FC

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:AT-rich interactive domain 3A (ARID3A) is a member of the ARID family of DNA-binding proteins. Previous reports have shown that ARID3A controls cell growth in a p53-dependent manner. Recently, it has been reported that expression of the ARID3A protein was markedly increased in colon cancer tissue compared wi...

journal_title：Annals of surgical oncology

authors： Song M,Kim H,Kim WK,Hong SP,Lee C,Kim H

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:More information is needed for selection of patients with peritoneal metastases from endometrial cancer (EC) to undergo cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC). METHODS:This study analyzed clinical, pathologic, and treatment data for patients with peritoneal metast...

journal_title：Annals of surgical oncology

authors： Cornali T,Sammartino P,Kopanakis N,Christopoulou A,Framarino Dei Malatesta M,Efstathiou E,Spagnoli A,Ciardi A,Biacchi D,Spiliotis J

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Extramammary Paget's disease (EMPD) is a rare intraepithelial malignancy with poorly described outcomes. EMPD in men is primarily found in the perianal and penoscrotal areas. We assessed incidence and time trends of EMPD in men as well as extent and predictors of survival using the Surveillance, Epidemiology...

journal_title：Annals of surgical oncology

authors： Herrel LA,Weiss AD,Goodman M,Johnson TV,Osunkoya AO,Delman KA,Master VA

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Limited data exist that describe the long-term outcomes from additional surgery following non-curative endoscopic resection (ER) of early gastric cancer (EGC) in older people. This study aimed to determine the appropriate treatment strategy for these patients. METHODS:We analyzed data from 2895 patients who...

journal_title：Annals of surgical oncology

authors： Pyo JH,Lee H,Min BH,Lee JH,Kim KM,Yoo H,Ahn S,An JY,Choi MG,Lee JH,Sohn TS,Bae JM,Kim JJ,Kim S

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:The purpose of this study is to establish the validity of F-18-deoxyglucose positron emission tomography-computed tomography (FDG-PET-CT) scan staging for cutaneous melanoma when a musculoskeletal image abnormality is detected. METHODS:An institutional review board (IRB)-approved prospective database was qu...

journal_title：Annals of surgical oncology

authors： Mansour AA 3rd,Kelley MC,Hatmaker AR,Holt GE,Schwartz HS

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:The risk factors and incidence of venous thromboembolism (VTE) are not well defined in patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC). We sought to characterize the incidence, risk factors, and pharmacothromboprophylaxis strategies for VTE after CRS/HIPEC....

journal_title：Annals of surgical oncology

authors： Khan S,Kelly KJ,Veerapong J,Lowy AM,Baumgartner JM

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Neoadjuvant chemotherapy (NAC) has been attempted as a means of improving survival of potentially resectable advanced gastric cancer (AGC). In the course of exploring the most promising NAC regimen, a superior surrogate marker reflecting overall survival (OS) is necessary. We investigated prognostic factors ...

journal_title：Annals of surgical oncology

authors： Fujitani K,Mano M,Hirao M,Kodama Y,Tsujinaka T

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Achieving an undetectable serum thyroglobulin (Tg) level (<1.0 ng/mL) after surgical and radioiodine treatment for papillary thyroid cancer (PTC) is associated with low recurrence rates and has been termed biochemical remission. This study aimed to determine the effectiveness of total thyroidectomy with ther...

journal_title：Annals of surgical oncology

authors： Hughes DT,Miller BS,Cohen MS,Doherty GM,Gauger PG

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:The extent of neck dissection (ND) appropriate for necks yielding clinical evidence of metastases of papillary thyroid carcinoma (PTC) is controversial. The need for level IIb lymph node (LN) dissection is particularly uncertain in view of its association with postoperative shoulder dysfunction. In the prese...

journal_title：Annals of surgical oncology

authors： Koo BS,Yoon YH,Kim JM,Choi EC,Lim YC

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Cancer treatment costs are not routinely addressed in shared decisions for breast cancer surgery. Thus, we sought to characterize cost awareness and communication among surgeons treating breast cancer. METHODS:We conducted a self-administered, confidential electronic survey among members of the American Soc...

journal_title：Annals of surgical oncology

authors： Greenup RA,Rushing CN,Fish LJ,Lane WO,Peppercorn JM,Bellavance E,Tolnitch L,Hyslop T,Myers ER,Zafar SY,Hwang ES

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Isolated hepatic perfusion (IHP) of chemotherapy has been proposed to deliver high doses of drug while avoiding systemic toxicity. Hypotonic cisplatin has a high in vitro activity on human colon cancer cells. We studied the safety of a 30-min hypoxic single-pass IHP with hypotonic cisplatin. METHODS:A preli...

journal_title：Annals of surgical oncology

authors： Ortega-Deballon P,Facy O,Consolo D,Magnin G,Tixier H,Simonet M,Rat P,Chauffert B

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:It is unclear whether hepatic resection (HR) or transarterial chemoembolization (TACE) is associated with better outcomes for patients with hepatocellular carcinoma (HCC) in Barcelona Clinic Liver Cancer (BCLC) stage A. The present study compared survival for patients with BCLC stage A HCC treated by HR or T...

journal_title：Annals of surgical oncology

authors： Guo Z,Zhong JH,Jiang JH,Zhang J,Xiang BD,Li LQ

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:L-phenylalanine mustard (LPAM) has been the standard for use in regional chemotherapy (RC) for unresectable in-transit melanoma. Preclinical data demonstrated that regional temozolomide (TMZ) may be more effective. METHODS:Patients with AJCC Stage IIIB or IIIC extremity melanoma who failed previous LPAM-bas...

journal_title：Annals of surgical oncology

authors： Beasley GM,Speicher P,Augustine CK,Dolber PC,Peterson BL,Sharma K,Mosca PJ,Royal R,Ross M,Zager JS,Tyler DS

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:There is a continuous interest in the literature concerning the management and survival after treatment of local recurrence in sarcomas because it is one of the most common types of recurrence. DESIGN:We retrospectively reviewed 93 patients treated for local recurrence from soft-tissue sarcoma. METHODS:We ...

journal_title：Annals of surgical oncology

authors： Karakousis CP,Proimakis C,Rao U,Velez AF,Driscoll DL

更新日期：1996-05-01 00:00:00

abstract：:Between 1980 and 2004, six randomized, controlled trials (RCTs) have been performed to evaluate the width of surgical margin excision for primary cutaneous melanoma and its influence on recurrence and survival. These trials have led to the current recommendation of not more than a 2-cm margin excision and have allowed...

journal_title：Annals of surgical oncology

authors： Angeles CV,Wong SL,Karakousis G

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Angiotensin 2 is a key biologic peptide in the renin-angiotensin system (RAS) that regulates blood pressure and renal hemodynamics. The potential role of the RAS in the promotion of tumor growth, angiogenesis, and metastasis also has been shown in the past few decades. This study investigated the prognostic ...

journal_title：Annals of surgical oncology

authors： Miyajima A,Yazawa S,Kosaka T,Tanaka N,Shirotake S,Mizuno R,Kikuchi E,Oya M

更新日期：2015-10-01 00:00:00