Pilot study of oncolytic viral therapy using mutant herpes simplex virus (HF10) against recurrent metastatic breast cancer.

abstract：BACKGROUND:Neoadjuvant endocrine therapy (NET) is effective in downstaging large hormone receptor-positive (HR+) breast cancers and increasing rates of breast-conserving surgery (BCS), but data regarding nodal pathologic complete response (pCR) are sparse. We reported nodal and breast downstaging rates with NET, and co...

journal_title：Annals of surgical oncology

authors： Montagna G,Sevilimedu V,Fornier M,Jhaveri K,Morrow M,Pilewskie ML

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Preoperative injection of radiocolloid before a sentinel lymph node (SLN) biopsy is painful for patients with breast cancer. Injection after anesthesia eliminates this discomfort but allows less time for radiocolloid migration. Our goal was to validate the efficacy of intraoperative injection. METHODS:In th...

journal_title：Annals of surgical oncology

authors： Stell VH,Flippo-Morton TS,Norton HJ,White RL Jr

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:The patients with early gastric cancer who have undergone incomplete endoscopic resection (ER) generally need additional surgery because of the possibility of lymph node metastasis. The aim of study was to evaluate the optimal time interval from ER to additive surgery by evaluating the effect of time interva...

journal_title：Annals of surgical oncology

authors： Kim MJ,Kim JH,Lee YC,Kim JW,Choi SH,Hyung WJ,Noh SH,Youn YH,Park H,Lee SI

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Pancreatic ductal adenocarcinoma (PDAC) frequently resists conventional cytotoxic therapy. The antitumor effects of endothelial monocyte-activating polypeptide II (EMAP) have been attributed to its antiendothelial and antiangiogenic activities. We tested the hypothesis that a combination of EMAP with bevaciz...

journal_title：Annals of surgical oncology

authors： Schwarz RE,Awasthi N,Konduri S,Cafasso D,Schwarz MA

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Hospitalization is associated with negative clinical effects that last beyond discharge. This study aimed to determine whether hospitalization in the year before major oncologic surgery is associated with adverse outcomes. METHODS:Patients 18 years of age or older with stomach, pancreas, colon, or rectal ca...

journal_title：Annals of surgical oncology

authors： Sharoky CE,Collier KT,Wirtalla CJ,Sinnamon AJ,Neuwirth MG,Kuo LE,Roses RE,Fraker DL,Karakousis GC,Kelz RR

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Findings show that 5-10 % of women with a diagnosis of breast cancer (BCa) have actionable genetic mutations. The National Comprehensive Cancer Network guidelines for testing to detect BRCA1/2 mutations include personal history (PH) variables such as age of 45 years or younger and a family history (FH) varia...

journal_title：Annals of surgical oncology

authors： Kishan AU,Gomez CL,Dawson NA,Dvorak R,Foster NM,Hoyt A,Hurvitz SA,Kusske A,Silver EL,Tseng C,McCloskey SA

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:American College of Surgeons Oncology Group Z0011 confirms the safety of omitting axillary lymph node dissection (ALND) and regional nodal irradiation (RNI) in breast cancer patients with one to two positive sentinel lymph nodes (SLNs), without compromising disease-free survival (DFS) and overall survival (O...

journal_title：Annals of surgical oncology

authors： Raber BM,Lin H,Shen Y,Shaitelman SF,Bedrosian I

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:The aim of this review was to examine the incidence of nipple-areola complex (NAC) involvement, the rates of NAC recurrence, and the data regarding the role of radiation therapy (RT) following nipple-sparing mastectomy (NSM). METHODS:A literature review was performed using the PubMed search engine, with articl...

journal_title：Annals of surgical oncology

authors： Gomez C,Shah C,McCloskey S,Foster N,Vicini F

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVES:To reject the hypothesis that the number of nodes removed at time of surgical staging for vulva cancer is not an important prognostic factor. METHODS:Retrospective chart reviews were carried out from 1980-2004 to identify patients with squamous cell vulva carcinoma treated with radical vulvectomy and bilate...

journal_title：Annals of surgical oncology

authors： Le T,Elsugi R,Hopkins L,Faught W,Fung-Kee-Fung M

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Preoperative devascularization might improve local control and thus the outcome of patients with soft tissue sarcoma (STS). The multikinase inhibitor pazopanib has antiangiogenic effects and is approved for treating metastatic STS. We conducted a trial of preoperative pazopanib therapy in high-risk STS. MET...

journal_title：Annals of surgical oncology

authors： Ronellenfitsch U,Karampinis I,Dimitrakopoulou-Strauss A,Sachpekidis C,Jakob J,Kasper B,Nowak K,Pilz L,Attenberger U,Gaiser T,Derigs HG,Schwarzbach M,Hohenberger P

更新日期：2019-05-01 00:00:00

abstract：: ...

journal_title：Annals of surgical oncology

authors： Kim BH,Chie EK,Kim K

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:There are few reports on microvascular invasion (MVI) located intra- or extratumorally and prognosis of hepatocellular carcinoma (HCC). OBJECTIVE:The aim of this study was to evaluate patient outcome according to the location of MVI, and to build a nomogram predicting extratumoral MVI. METHODS:We included ...

journal_title：Annals of surgical oncology

authors： Nitta H,Allard MA,Sebagh M,Ciacio O,Pittau G,Vibert E,Sa Cunha A,Cherqui D,Castaing D,Bismuth H,Guettier C,Lewin M,Samuel D,Baba H,Adam R

更新日期：2019-08-01 00:00:00

abstract：INTRODUCTION:Retroperitoneal soft tissue sarcomas (RPSs) are mesenchymal neoplasms. The prevalence of protein energetic malnutrition (PEM) and its impact in RPS patients who were candidates for surgery is unknown. MATERIALS AND METHODS:A prospective feasibility study enrolled 35 patients with primary RPS who were cand...

journal_title：Annals of surgical oncology

authors： Previtali P,Fiore M,Colombo J,Arendar I,Fumagalli L,Pizzocri M,Colombo C,Rampello NN,Mariani L,Gronchi A,Codazzi D

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Male breast cancer accounts for less than 1% of all breast cancers, yet males have a worse prognosis than females with breast cancer. METHODS:Using the 1988-2003 Surveillance, Epidemiology, and End Results Program data, we conducted a retrospective, population-based cohort study to investigate stage-specifi...

journal_title：Annals of surgical oncology

authors： Gnerlich JL,Deshpande AD,Jeffe DB,Seelam S,Kimbuende E,Margenthaler JA

更新日期：2011-07-01 00:00:00

abstract：:Integrins play an important role in various lymphocyte functions. In this study, we isolated lamina propria lymphocytes (LPL) and tumor-infiltrating lymphocytes (TIL) from normal and malignant tissues in patients with colorectal cancer, and examined the expression of beta1 and beta2 integrins on these lymphocytes quan...

journal_title：Annals of surgical oncology

authors： Kitayama J,Tuno N,Nakayama H,Shibata Y,Muto T,Nagawa H

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:This work is aimed at comparing mucinous colorectal adenocarcinomas (MUC) and non-mucinous colorectal adenocarcinomas (non-MUC), and at verifying the existence of two different subgroups of MUC, in terms of clinicopathological features, chromosomal alterations, and outcome, in a geographical area where mucin...

journal_title：Annals of surgical oncology

authors： Leopoldo S,Lorena B,Cinzia A,Gabriella DC,Angela Luciana B,Renato C,Antonio M,Carlo S,Cristina P,Stefano C,Maurizio T,Luigi R,Cesare B

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Goblet cell carcinoma (GCC) of the appendix is a rare disease. Treatment options vary according to disease staging. Cytoreductive surgery in combination with hyperthermic intraperitoneal chemotherapy (CRS + HIPEC) may improve survival in patients with peritoneal spreading. OBJECTIVE:The aim of this study wa...

journal_title：Annals of surgical oncology

authors： Madsen AH,Ladekarl M,Villadsen GE,Grønbæk H,Sørensen MM,Stribolt K,Verwaal VJ,Iversen LH

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:We provide a statistical analysis of the learning phase for sentinel node biopsy. METHODS:Four learning phases were analyzed: 25, 50, 75, and 150 procedures with a corresponding number of 10, 20, 30, and 60 tumor-positive cases. Critical values of nonidentification rate and false-negative rate were defined....

journal_title：Annals of surgical oncology

authors： Tanis PJ,Nieweg OE,Hart AA,Kroon BB

更新日期：2002-03-01 00:00:00

abstract：: ...

journal_title：Annals of surgical oncology

authors： Goffredo P,Hassan I

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The benefits of hepatic transplantation (HT) compared with hepatic resection (HR) in treating hepatocellular carcinoma (HCC) in patients with cirrhosis are controversial. The aim of this study was to compare the results of these therapeutic options. METHODS:The charts of all patients with cirrhosis who unde...

journal_title：Annals of surgical oncology

authors： Shabahang M,Franceschi D,Yamashiki N,Reddy R,Pappas PA,Aviles K,Flores S,Chaparro A,Levi JU,Sleeman D,Tzakis AG,Kato T,Levi DM,Livingstone AS

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Peritoneal carcinomatosis (PC), which has hitherto been regarded as a lethal entity, can now be cured with surgery (treating macroscopic tumor seeding) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) (treating residual microscopic disease). The purpose of this study was to analyze the morbidi...

journal_title：Annals of surgical oncology

authors： Elias D,Goere D,Blot F,Billard V,Pocard M,Kohneh-Shahri N,Raynard B

更新日期：2007-06-01 00:00:00

abstract：:The Chicago Consensus Working Group provides multidisciplinary recommendations for the management of colorectal cancer specifically as it relates to the management of peritoneal surface malignancy. These guidelines are developed with input from leading experts including surgical oncologists, medical oncologists, patho...

journal_title：Annals of surgical oncology

authors： Chicago Consensus Working Group.

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor (VEGF), a key regulator of angiogenesis, is critical for growth of human pancreatic adenocarcinoma. Preclinical studies demonstrate that blockade of VEGF activity can control the growth of pancreatic tumors in mice. In this study, we evaluated the efficacy of 2C3, an antibo...

journal_title：Annals of surgical oncology

authors： Holloway SE,Beck AW,Shivakumar L,Shih J,Fleming JB,Brekken RA

更新日期：2006-08-01 00:00:00

abstract：INTRODUCTION:Evidence from the American College of Surgeons Oncology Group (ACOSOG) Z0011 trial suggests completion axillary lymph node dissection (cALND) after positive sentinel lymph node biopsy (+SLNB) does not improve outcomes in select patients, leading to practice variation. A multidisciplinary group of surgeons,...

journal_title：Annals of surgical oncology

authors： Tsao MW,Cornacchi SD,Hodgson N,Simunovic M,Thabane L,Cheng J,O'Brien MA,Strang B,Mukherjee SD,Lovrics PJ

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Oral squamous cell carcinoma (OSCC) is prevalent worldwide, and survival in OSCC has not improved significantly in the last few decades. MicroRNAs have an important regulatory role in oral carcinogenesis. This study investigated the prognostic implications of miR-196 expression and the rs11614913 genotype of...

journal_title：Annals of surgical oncology

authors： Liu CJ,Tsai MM,Tu HF,Lui MT,Cheng HW,Lin SC

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:Retroperitoneal sarcomas (RPS) are rare malignancies, comprising just 10-15 % of all soft-tissue sarcomas. These are challenging tumors to treat, with surgical resection being the only modality capable of providing a cure. This study analyzed the management and survival of patients resected at a large academic ...

journal_title：Annals of surgical oncology

authors： Bremjit PJ,Jones RL,Chai X,Kane G,Rodler ET,Loggers ET,Pollack SM,Pillarisetty VG,Mann GN

更新日期：2014-07-01 00:00:00

abstract：INTRODUCTION:Inguinal lymphadenectomy for metastatic melanoma is reported to have a complication rate as high as 50%. Wound dehiscence has been reported to occur in more than half of these patients, and as a result many surgeons routinely use sartorius muscle transposition to protect against the potential for exposed v...

journal_title：Annals of surgical oncology

authors： Delman KA,Kooby DA,Ogan K,Hsiao W,Master V

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Performing a sentinel lymph node biopsy (SLNB) is the standard of care for axillary nodal staging in patients with invasive breast cancer and clinically negative nodes. The procedure provides valuable staging information with few complications when performed by experienced surgeons. However, variation in pro...

journal_title：Annals of surgical oncology

authors： James TA,Coffman AR,Chagpar AB,Boughey JC,Klimberg VS,Morrow M,Giuliano AE,Harlow SP

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:This study aimed to evaluate the impact that the release of consensus guidelines for margins in breast-conserving surgery (BCS) had on re-excision rates. METHODS:A retrospective review examined a prospectively maintained database of patients who had operable invasive breast cancer treated with BCS at the au...

journal_title：Annals of surgical oncology

authors： Chung A,Gangi A,Amersi F,Bose S,Zhang X,Giuliano A

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Cancer patients have often been reported to have impaired immune function, and the effect of treatment modalities, such as surgery, irradiation, and chemotherapy, in depressing patients' immunity has also been reported. In this investigation, the effect of treatment on the cellular immunity of esophageal can...

journal_title：Annals of surgical oncology

authors： Mafune K,Tanaka Y

更新日期：2000-09-01 00:00:00