Abstract：
BACKGROUND:We provide a statistical analysis of the learning phase for sentinel node biopsy. METHODS:Four learning phases were analyzed: 25, 50, 75, and 150 procedures with a corresponding number of 10, 20, 30, and 60 tumor-positive cases. Critical values of nonidentification rate and false-negative rate were defined. The binomial distribution was used to calculate the probabilities of correctly or incorrectly accepting the quality of the performance, given a certain long-term nonidentification or false-negative rate. RESULTS:The chance of incorrectly reaching a favorable false-negative rate of <10% (critical value) in 20 metastasized patients was 18% for a surgeon with a long-term probability of false-negative procedures of 15%. This chance was reduced to 10% with a learning phase of 60 tumor-positive cases. When this chance has to be further reduced to 5%, the critical value has to be lower in smaller groups of patients: 5% false-negative rate in 20 tumor-positive procedures. CONCLUSIONS:A learning phase of at least 150 procedures with 60 tumor-positive cases is needed to draw any reliable conclusion about the quality of sentinel node biopsy. In general, a compromise has to be made between the reliability of the results and the practically achievable number of procedures.
journal_name
Ann Surg Oncoljournal_title
Annals of surgical oncologyauthors
Tanis PJ,Nieweg OE,Hart AA,Kroon BBdoi
10.1007/BF02557365keywords:
subject
Has Abstractpub_date
2002-03-01 00:00:00pages
142-7issue
2eissn
1068-9265issn
1534-4681journal_volume
9pub_type
杂志文章abstract：: ...
journal_title：Annals of surgical oncology
pub_type： 评论,杂志文章
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pub_type： 杂志文章
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journal_title：Annals of surgical oncology
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journal_title：Annals of surgical oncology
pub_type： 杂志文章
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更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:There have been no nationwide surveys of postoperative adverse events (AEs) after musculoskeletal tumor surgery focusing on their severity. Therefore, we developed a nomogram to predict severe AEs after musculoskeletal tumor surgery. METHODS:We identified patients in the Diagnosis Procedure Combination data...
journal_title：Annals of surgical oncology
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journal_title：Annals of surgical oncology
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doi：10.1245/s10434-017-6017-x
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abstract：BACKGROUND:Thyroidectomy and parathyroidectomy are the most commonly performed endocrine operations, and are increasingly being completed on a same-day basis; however, few data exist regarding the outpatient postoperative pain requirement of these patients. We aimed to describe the outpatient narcotic medication needs ...
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pub_type： 杂志文章,多中心研究
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更新日期：2011-09-01 00:00:00
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journal_title：Annals of surgical oncology
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更新日期：2017-03-01 00:00:00
abstract：BACKGROUND:Cholangiocarcinoma can be classified in intrahepatic cholangiocarcinoma (ICC) and perihilar cholangiocarcinoma (PCC). Moreover, PCC includes two different forms: extrahepatic (EH) PCC, which arises from the perihilar EH large ducts, and intrahepatic (IH) PCC, in which a significant liver mass invades the per...
journal_title：Annals of surgical oncology
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doi：10.1245/s10434-015-5046-6
更新日期：2016-05-01 00:00:00
