Msi-1 is a predictor of survival and a novel therapeutic target in colon cancer.

abstract：BACKGROUND:A recent study showed that circulating exosomal PD-L1 is an effective predictor for anti-PD-1 therapy in melanomas. Exosomal PD-L1 induced immunosuppression microenvironments in cancer patients. However, its prognostic value and immunosuppressive effect in gastric cancer (GC) were poorly understood. METHODS...

journal_title：Annals of surgical oncology

authors： Fan Y,Che X,Qu J,Hou K,Wen T,Li Z,Li C,Wang S,Xu L,Liu Y,Qu X

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Patients with biliary tract adenocarcinoma with nodal involvement have a poor prognosis. There is currently no standardized method for intraoperative lymph node assessment. The current study aimed to determine the prognostic significance of the highest peripancreatic lymph node (HPLN) in biliary tract malign...

journal_title：Annals of surgical oncology

authors： Kelly KJ,Dukleska K,Kuk D,Kingham TP,D'Angelica MI,DeMatteo RP,Allen PJ,Jarnagin WR,Fong Y

更新日期：2014-03-01 00:00:00

abstract：PURPOSE:The optimal management of colorectal cancer liver metastases (CRC-LM) has changed during the past two decades. However, clinical practice lags behind best evidence recommendations. We sought to characterize the gap between current practice and best evidence for the management of these patients and to identify b...

journal_title：Annals of surgical oncology

authors： Wei AC,Sandhu L,Devitt KS,Gagliardi AR,Kennedy ED,Urbach DR,Gallinger S,Baxter NN

更新日期：2013-05-01 00:00:00

abstract：INTRODUCTION:To identify melanoma patients at sufficiently low risk of nodal metastases who could avoid sentinel lymph node biopsy (SLNB), several statistical models have been proposed based upon patient/tumor characteristics, including logistic regression, classification trees, random forests, and support vector machi...

journal_title：Annals of surgical oncology

authors： Sabel MS,Rice JD,Griffith KA,Lowe L,Wong SL,Chang AE,Johnson TM,Taylor JM

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:We attempted to determine factors contributing to the extent of initial curative resection for colon cancer in a population-based cohort. Total abdominal colectomy with ileorectal anastomosis (TAC-IR) may be considered for young patients or those with a colorectal cancer family history to prevent metachronou...

journal_title：Annals of surgical oncology

authors： Easson AM,Cotterchio M,Crosby JA,Sutherland H,Dale D,Aronson M,Holowaty E,Gallinger S

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:This study aimed to evaluate the impact that the release of consensus guidelines for margins in breast-conserving surgery (BCS) had on re-excision rates. METHODS:A retrospective review examined a prospectively maintained database of patients who had operable invasive breast cancer treated with BCS at the au...

journal_title：Annals of surgical oncology

authors： Chung A,Gangi A,Amersi F,Bose S,Zhang X,Giuliano A

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:We investigated the possible lobe-specific lymph node (LN) metastasis pattern of early-stage peripheral non-small cell lung cancers (NSCLC) and define the extent of lobe-specific LN dissection for them. METHODS:We retrospectively collected clinical data of patients undergoing lobectomy or segmentectomy with ...

journal_title：Annals of surgical oncology

authors： Deng HY,Zhou J,Wang RL,Jiang R,Zhu DX,Tang XJ,Zhou Q

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Sentinel node biopsy (SNB) is commonly performed in contemporary melanoma management, however there is a paucity of long-term quality of life (QoL) estimates required for economic evaluation of this treatment. METHODS:A single-center, prospective, cross-sectional study of adults with American Joint Committe...

journal_title：Annals of surgical oncology

authors： Morton RL,Tran A,Vessey JY,Rowbotham N,Winstanley J,Shannon K,Spillane AJ,Stretch J,Thompson JF,Saw RP

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Recently, it was reported that minimally invasive surgery (MIS) has a negative impact on early-stage cervical cancer (ECC) patient survival. At the same time, advantages of MIS regarding quality of life and low rate of intra- and postoperative complications are well known. Therefore, it is essential to selec...

journal_title：Annals of surgical oncology

authors： Pedone Anchora L,Turco LC,Bizzarri N,Capozzi VA,Lombisani A,Chiantera V,De Felice F,Gallotta V,Cosentino F,Fagotti A,Ferrandina G,Scambia G

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:We provide a statistical analysis of the learning phase for sentinel node biopsy. METHODS:Four learning phases were analyzed: 25, 50, 75, and 150 procedures with a corresponding number of 10, 20, 30, and 60 tumor-positive cases. Critical values of nonidentification rate and false-negative rate were defined....

journal_title：Annals of surgical oncology

authors： Tanis PJ,Nieweg OE,Hart AA,Kroon BB

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Management of patients with neuroendocrine liver metastasis (NELM) remains controversial. We sought to examine the relative efficacy of surgical management versus intra-arterial therapy (IAT) for NELM and determine factors predictive of survival. METHODS:A total of 753 patients who had surgery (n = 339) or ...

journal_title：Annals of surgical oncology

authors： Mayo SC,de Jong MC,Bloomston M,Pulitano C,Clary BM,Reddy SK,Clark Gamblin T,Celinski SA,Kooby DA,Staley CA,Stokes JB,Chu CK,Arrese D,Ferrero A,Schulick RD,Choti MA,Geschwind JF,Strub J,Bauer TW,Adams RB,Aldrighett

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Male breast cancer accounts for less than 1% of all breast cancers, yet males have a worse prognosis than females with breast cancer. METHODS:Using the 1988-2003 Surveillance, Epidemiology, and End Results Program data, we conducted a retrospective, population-based cohort study to investigate stage-specifi...

journal_title：Annals of surgical oncology

authors： Gnerlich JL,Deshpande AD,Jeffe DB,Seelam S,Kimbuende E,Margenthaler JA

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Percutaneous biliary drainage (PBD) is used to relieve malignant bile duct obstruction (MBO) when endoscopic drainage is not feasible. Little is known about the effects of PBD on the quality of life (QoL) in patients with MBO. The aim of this study was to evaluate changes in QoL and pruritus after PBD and to...

journal_title：Annals of surgical oncology

authors： Robson PC,Heffernan N,Gonen M,Thornton R,Brody LA,Holmes R,Brown KT,Covey AM,Fleischer D,Getrajdman GI,Jarnagin W,Sofocleous C,Blumgart L,D'Angelica M

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Although an age cutoff of 45 years has often been adopted to stratify cancer risk in papillary thyroid carcinoma (PTC), both cancer-specific survival (CSS) and disease-specific survival (DFS) continue to worsen beyond this cutoff. This study aimed to determine whether advanced age (i.e., >60 years) at diagno...

journal_title：Annals of surgical oncology

authors： Lang BH,Lo CY,Wong KP,Wan KY

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Early gastric cancer that meets the expanded criteria for endoscopic resection (ER) is expected to be associated with a negligible risk for lymph node metastasis (LNM); however, recent studies have reported LNM in submucosal gastric cancer patients who met the existing criteria. In this study, we develop the...

journal_title：Annals of surgical oncology

authors： Ma DW,Lee SJ,Kook MC,Park DY,Ahn S,Ryu KW,Choi IJ,Noh SH,Kim H,Lee YC,Kim JH

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Trastuzumab in association with systemic cytotoxic chemotherapy is the standard of care for patients with advanced HER2-positive gastric carcinoma (GC). However, HER2 as a prognostic factor in GC remains controversial. METHODS:HER2 overexpression and amplification was evaluated by immunohistochemistry (IHC)...

journal_title：Annals of surgical oncology

authors： Cho J,Jeong J,Sung J,Sung CO,Kim KM,Park CK,Choi MG,Sohn TS,Bae JM,Kim S

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Hepatic resection is potentially curative in selected patients with colorectal metastases. It is a widely held practice that multiple colorectal hepatic metastases are not resected, although outcome after removal of four or more metastases is not well defined. METHODS:Patients with four or more colorectal h...

journal_title：Annals of surgical oncology

authors： Weber SM,Jarnagin WR,DeMatteo RP,Blumgart LH,Fong Y

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Nonsurgical assessment of sentinel nodes (SNs) would offer advantages over surgical SN excision by reducing morbidity and costs. Proton magnetic resonance spectroscopy (MRS) of fine-needle aspirate biopsy (FNAB) specimens identifies melanoma lymph node metastases. This study was undertaken to determine the a...

journal_title：Annals of surgical oncology

authors： Stretch JR,Somorjai R,Bourne R,Hsiao E,Scolyer RA,Dolenko B,Thompson JF,Mountford CE,Lean CL

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Isolated limb perfusion (ILP) results in complete response (CR) rates of 60% to 90% in patients with regionally advanced melanoma. Survival after a CR may be influenced by various factors, particularly out-of-field disease in iliac lymph nodes (ILN) identified during lower-extremity ILP. We examined clinical...

journal_title：Annals of surgical oncology

authors： Zogakis TG,Bartlett DL,Libutti SK,Liewehr DJ,Steinberg SM,Fraker DL,Alexander HR

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:A patient's likelihood of dying from breast cancer or another cause can be assessed with competing risks analyses. METHODS:Data for a cohort of 678 patients with primary invasive breast cancer accrued from 1971 to 1990, updated to 1995, included cause of death (e.g., breast cancer vs. other cause). We inves...

journal_title：Annals of surgical oncology

authors： Fish EB,Chapman JA,Link MA

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:Local treatment of colorectal cancer, including endoscopic removal of colonic polyps and transanal resection of rectal tumors, has become widely accepted. However, risk factors predicting the presence of lymph node metastasis have not been fully investigated. To determine the criteria for local excision of c...

journal_title：Annals of surgical oncology

authors： Adachi Y,Yasuda K,Kakisako K,Sato K,Shiraishi N,Kitano S

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Residual tumor size after neoadjuvant chemotherapy is an important consideration in surgical planning. We examined the accuracy of the combination of mammography and sonography in predicting pathologic residual tumor size. METHODS:Tumor size was evaluated by physical examination, mammography, and sonography...

journal_title：Annals of surgical oncology

authors： Peintinger F,Kuerer HM,Anderson K,Boughey JC,Meric-Bernstam F,Singletary SE,Hunt KK,Whitman GJ,Stephens T,Buzdar AU,Green MC,Symmans WF

更新日期：2006-11-01 00:00:00

abstract：PURPOSE:The purpose of this study was to identify prognostic genes by integrated microarray analysis between comparative genomic hybridization and gene expression with laser microdissection in non-small cell lung cancer (NSCLC). METHODS:Integrated microarray analysis in 11 lung adenocarcinomas was performed, and sever...

journal_title：Annals of surgical oncology

authors： Sakashita H,Inoue H,Akamine S,Ishida T,Inase N,Shirao K,Mori M,Mimori K

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Low incidence of breast cancer in men (BCM) (< 1% of all breast cancers) has led to a paucity of outcome data. This study evaluated the impact of age on BCM outcomes. METHODS:For this study, BCM patients treated between 2000 and 2011 were stratified by age (≤ 65 or > 65 years). Kaplan-Meier methods were use...

journal_title：Annals of surgical oncology

authors： Cronin PA,Romanoff A,Zabor EC,Stempel M,Eaton A,Smyth LM,Ho AY,Morrow M,El-Tamer M,Gemignani ML

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Neuroendocrine tumors are becoming increasingly prevalent, with many patients presenting with or developing metastatic disease to the liver. METHODS:In this landmark series paper, we highlight the critical studies that have defined the surgical management of neuroendocrine tumor liver metastases, as well as...

journal_title：Annals of surgical oncology

authors： Gangi A,Howe JR

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Calciphylaxis is a rare condition associated with chronic renal failure and entails a very poor prognosis. Pathogenesis is poorly understood but involves abnormalities in calcium and phosphorus metabolism that lead to vascular and extravascular calcification. Patients present with painful ulcerating plaques ...

journal_title：Annals of surgical oncology

authors： Duffy A,Schurr M,Warner T,Chen H

更新日期：2006-01-01 00:00:00

abstract：PURPOSE:To report outcomes for breast-conserving therapy using adjuvant accelerated partial breast irradiation with interstitial multicatheter brachytherapy by a cooperative group of institutions. METHODS:From 1992 to 2013, a total of 1356 patients were treated with breast-conserving surgery and adjuvant accelerated p...

journal_title：Annals of surgical oncology

authors： Kamrava M,Kuske RR,Anderson B,Chen P,Hayes J,Quiet C,Wang PC,Veruttipong D,Snyder M,Jeffrey Demanes D

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:In patients with colorectal hepatic metastases, response rates with hepatic arterial infusion (HAI) FUdR (5-Fluoro-2-deoxyuridine) are significantly higher than with systemic fluoropyrimidines. We report a novel animal model of intrahepatic therapy for hepatic metastasis for the study of methods to increase ...

journal_title：Annals of surgical oncology

authors： Sutanto-Ward E,Arisawa Y,Tremiterra S,Sigurdson ER

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Little data are available regarding individual patients' risk of surgical site infection (SSI) following mastectomy with or without immediate reconstruction. Our objective was to develop a risk prediction model for mastectomy-related SSI. METHODS:Using commercial claims data, we established a cohort of wome...

journal_title：Annals of surgical oncology

authors： Olsen MA,Nickel KB,Margenthaler JA,Fox IK,Ball KE,Mines D,Wallace AE,Colditz GA,Fraser VJ

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Repeat sentinel lymph node biopsy (rSLNB) has increasingly been used in patients with ipsilateral breast tumor recurrence (IBTR). The safety in terms of regional disease control after this procedure remains unclear. This study evaluates occurrence of regional recurrence as first event in patients with IBTR a...

journal_title：Annals of surgical oncology

authors： Poodt IGM,Vugts G,Maaskant-Braat AJG,Schipper RJ,Voogd AC,Nieuwenhuijzen GAP,Sentinel Node and Recurrent Breast Cancer (SNARB) study group.

更新日期：2018-05-01 00:00:00