Exosomal PD-L1 Retains Immunosuppressive Activity and is Associated with Gastric Cancer Prognosis.

abstract：OBJECTIVE:The aim of this study was to investigate the correlation between clinical complete response (cCR) and pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (CRT) for esophageal squamous cell cancer (ESCC). METHODS:Between May 2001 and April 2013, a total of 158 patients with thoracic ESCC tr...

journal_title：Annals of surgical oncology

authors： Liu SL,Xi M,Yang H,Yang YD,Wu YJ,Zhao L,Zhang P,Luo LL,Liu MZ

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Noninvasive thermal ablation using magnetic resonance (MR)-guided focused ultrasound (MRgFUS) has been shown to be clinically effective in uterine fibroids, and is being evaluated for ablation of breast, liver, and brain lesions. Recently MRgFUS has been evaluated for palliation of pain caused by bone metast...

journal_title：Annals of surgical oncology

authors： Liberman B,Gianfelice D,Inbar Y,Beck A,Rabin T,Shabshin N,Chander G,Hengst S,Pfeffer R,Chechick A,Hanannel A,Dogadkin O,Catane R

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Axillary nodal status is the most important prognostic factor for patients with breast cancer. Clinical assessment and imaging modalities are not always reliable. Surgical removal and histopathological examination of axillary lymph nodes remain essential methods of staging the axilla. However, the optimal ma...

journal_title：Annals of surgical oncology

authors： Samphao S,Eremin JM,El-Sheemy M,Eremin O

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Limited data are available on the use of cytoreductive surgery with hyperthermic intraperitoneal chemoperfusion (HIPEC) in patients with recurrent stage III ovarian cancer. METHODS:Patients with recurrent, heavily pretreated ovarian cancer were enrolled onto a phase II multimodal protocol consisting of exte...

journal_title：Annals of surgical oncology

authors： Ceelen WP,Van Nieuwenhove Y,Van Belle S,Denys H,Pattyn P

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Autophagy plays a major role in cellular homeostasis and is implicated in cancer progression. Damaged mitochondria are scavenged and eliminated by mitochondrial autophagy, referred to as mitophagy, which can promote cancer cell survival. This study investigated the expression and effects of the autophagy-rel...

journal_title：Annals of surgical oncology

authors： Yamashita K,Miyata H,Makino T,Masuike Y,Furukawa H,Tanaka K,Miyazaki Y,Takahashi T,Kurokawa Y,Yamasaki M,Nakajima K,Takiguchi S,Morii E,Mori M,Doki Y

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Dysregulation of apoptosis is a key factor in carcinogenesis and tumor progression. X-linked inhibitor of apoptosis (XIAP) is the most potent member of the inhibitor of apoptosis protein (IAP) family, which directly inhibits apoptosis by binding to caspases. Antagonists of XIAP have recently been identified:...

journal_title：Annals of surgical oncology

authors： Shibata T,Noguchi T,Takeno S,Gabbert HE,Ramp U,Kawahara K

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Preoperative nutritional status not only correlates with the incidence of postoperative complications but also may be indicative of long-term outcomes for patients with cancer. The impact of preoperative nutritional status on outcomes for patients undergoing gastrectomy for gastric cancer (GC) was investigat...

journal_title：Annals of surgical oncology

authors： Sakurai K,Ohira M,Tamura T,Toyokawa T,Amano R,Kubo N,Tanaka H,Muguruma K,Yashiro M,Maeda K,Hirakawa K

更新日期：2016-02-01 00:00:00

abstract：PURPOSE:Neuropathic pain (NPP) following breast surgery extends morbidity in the postoperative period. The incidence and etiology of postoperative NPP remains unclear and under-reported in literature. This study aims to define the incidence of neuropathic pain following breast surgery and to identify patient characteri...

journal_title：Annals of surgical oncology

authors： Wilson GC,Quillin RC 3rd,Hanseman DJ,Lewis JD,Edwards MJ,Shaughnessy EA

更新日期：2013-10-01 00:00:00

abstract：: ...

journal_title：Annals of surgical oncology

authors：

更新日期：2019-02-01 00:00:00

abstract：: ...

journal_title：Annals of surgical oncology

authors： Lopez-Aguiar AG,Cardona K

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:It is still controversial whether tumor size (Ts) should be considered an important indicator for evaluation the prognosis of gastric cancer (GC). The purpose of this study was to elucidate the prognostic prediction superiority of Ts in the large-scale cohort of GC patients. METHODS:Data from 1,521 patients...

journal_title：Annals of surgical oncology

authors： Deng J,Zhang R,Pan Y,Ding X,Cai M,Liu Y,Liu H,Bao T,Jiao X,Hao X,Liang H

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Cancer patients have often been reported to have impaired immune function, and the effect of treatment modalities, such as surgery, irradiation, and chemotherapy, in depressing patients' immunity has also been reported. In this investigation, the effect of treatment on the cellular immunity of esophageal can...

journal_title：Annals of surgical oncology

authors： Mafune K,Tanaka Y

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:There have been no nationwide surveys of postoperative adverse events (AEs) after musculoskeletal tumor surgery focusing on their severity. Therefore, we developed a nomogram to predict severe AEs after musculoskeletal tumor surgery. METHODS:We identified patients in the Diagnosis Procedure Combination data...

journal_title：Annals of surgical oncology

authors： Ogura K,Yasunaga H,Horiguchi H,Fushimi K,Tanaka S,Kawano H

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Cysteine/histidine-rich 1 (CYHR1) was first discovered in a yeast two-hybrid screen with murine galectin-3, and no previous reports have described a relationship between the CYHR1 gene and human cancer. The current study evaluated the role and significance of CYHR1 in esophageal cancer. METHODS:The human es...

journal_title：Annals of surgical oncology

authors： Desaki R,Sawada G,Okumura H,Ikeda R,Tanabe K,Komatsu H,Mimori K,Mori M,Kita Y,Uchikado Y,Arigami T,Uenosono Y,Owaki T,Ishigami S,Natsugoe S

更新日期：2017-02-01 00:00:00

abstract：INTRODUCTION:The clinical significance of isolated tumor cells (ITC) in peripheral blood (PB) and bone marrow (BM) as predictive markers in the recurrence or metastasis of breast cancer has not yet been determined. In the current study, we focused on the urokinase plasminogen activator receptor (u-PAR) gene as a powerf...

journal_title：Annals of surgical oncology

authors： Mimori K,Kataoka A,Yamaguchi H,Masuda N,Kosaka Y,Ishii H,Ohno S,Mori M

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:This study was designed to evaluate the outcome of patients with uterine carcinosarcoma undergoing sentinel lymph node (SLN) mapping. METHODS:A prospectively maintained database was reviewed for all women with uterine cancer treated at our institution from January 1, 1998 to August 31, 2014. Patients were grou...

journal_title：Annals of surgical oncology

authors： Schiavone MB,Zivanovic O,Zhou Q,Leitao MM Jr,Levine DA,Soslow RA,Alektiar KM,Makker V,Iasonos A,Abu-Rustum NR

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the usefulness of shear wave elastography (SWE) for predicting cervical lymph node (LN) metastasis and the prognostic implication of SWE as histopathologic factors of papillary thyroid carcinoma (PTC). METHODS:Eighty-four LNs of 66 patients with PTC underwent B-mode ultras...

journal_title：Annals of surgical oncology

authors： Jung WS,Kim JA,Son EJ,Youk JH,Park CS

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Intraperitoneal chemotherapy is used to treat peritoneal surface-spreading malignancies. We sought to determine whether volume and surface area of the intraperitoneal chemotherapy compartments are associated with overall survival and posttreatment glomerular filtration rate (GFR) in malignant peritoneal meso...

journal_title：Annals of surgical oncology

authors： Leinwand JC,Zhao B,Guo X,Krishnamoorthy S,Qi J,Graziano JH,Slavkovic VN,Bates GE,Lewin SN,Allendorf JD,Chabot JA,Schwartz LH,Taub RN

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:There are few reports on a dual dye and isotope approach using laparoscopy in gastric cancer sentinel node mapping. The aim of this study is to evaluate the feasibility of laparoscopic sentinel basin dissection for gastric cancer using simultaneous indocyanine green (ICG) and (99m)Tc-antimony sulfur colloid ...

journal_title：Annals of surgical oncology

authors： Park DJ,Kim HH,Park YS,Lee HS,Lee WW,Lee HJ,Yang HK

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The recent introduction of biological anticancer therapy has renewed the interest in functional imaging of tumor-associated angiogenesis (TAA) as a tool to monitor early therapy response. The present study evaluated imaging of TAA using P1227, a novel, small molecular magnetic resonance imaging (MRI) probe t...

journal_title：Annals of surgical oncology

authors： Debergh I,Van Damme N,De Naeyer D,Smeets P,Demetter P,Robert P,Carme S,Pattyn P,Ceelen W

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Recent studies indicate that women with unilateral breast cancer are choosing contralateral prophylactic mastectomy (CPM) at an increasing rate. There is limited literature evaluating the postoperative complication rates associated with CPM without breast reconstruction. The objective of this study was to co...

journal_title：Annals of surgical oncology

authors： Osman F,Saleh F,Jackson TD,Corrigan MA,Cil T

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:AT-rich interactive domain 3A (ARID3A) is a member of the ARID family of DNA-binding proteins. Previous reports have shown that ARID3A controls cell growth in a p53-dependent manner. Recently, it has been reported that expression of the ARID3A protein was markedly increased in colon cancer tissue compared wi...

journal_title：Annals of surgical oncology

authors： Song M,Kim H,Kim WK,Hong SP,Lee C,Kim H

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Effective therapeutic combinations targeting the oncogenic pathway still are unknown in human hepatocellular carcinoma (HCC). The authors previously identified aberrant expression of aurora B kinase as the independent predictor for the lethal recurrence of HCC, showing that AZD1152 induced in vitro and in vi...

journal_title：Annals of surgical oncology

authors： Matsunaga H,Tanaka S,Aihara A,Ogawa K,Matsumura S,Ban D,Ochiai T,Irie T,Kudo A,Nakamura N,Arii S,Tanabe M

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:COX inhibitors and beta-blockers were recently suggested to reduce cancer progression through inhibition of tumor proliferation and growth factor secretion, induction of tumor apoptosis, and prevention of cellular immune suppression during the critical perioperative period. Here we evaluated the perioperativ...

journal_title：Annals of surgical oncology

authors： Benish M,Bartal I,Goldfarb Y,Levi B,Avraham R,Raz A,Ben-Eliyahu S

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Laparoscopic liver resection for perihilar cholangiocarcinoma (pCCA) is still in its infancy. The biliary-enteric reconstruction represents one of the most delicate parts of this minimally invasive procedure. METHODS:In this study, a 78-year old woman with perihilar cholangiocarcinoma (pCCA) type 3b underwe...

journal_title：Annals of surgical oncology

authors： Sucher R,Scheuermann U,Seehofer D

更新日期：2020-09-30 00:00:00

abstract：BACKGROUND:Functional chemokine receptors are expressed in many malignant tumors, including papillary thyroid carcinoma (PTC). These receptors promote tumor growth and metastasis in response to endogenous chemokines. The purpose of this study was to examine the expression of two chemokine receptors-CXCR4 and CCR7-in a ...

journal_title：Annals of surgical oncology

authors： Wagner PL,Moo TA,Arora N,Liu YF,Zarnegar R,Scognamiglio T,Fahey TJ 3rd

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Preliminary data indicate that tyrosine kinase inhibitors (TKIs) function through rearranged during transfection (RET) in breast cancer. However, TKIs are not specific and can block several receptor tyrosine kinases (RTKs). This study used cell lines and primary breast cancer specimens to determine factors a...

journal_title：Annals of surgical oncology

authors： Spanheimer PM,Lorenzen AW,De Andrade JP,Kulak MV,Carr JC,Woodfield GW,Sugg SL,Weigel RJ

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Local treatment of colorectal cancer, including endoscopic removal of colonic polyps and transanal resection of rectal tumors, has become widely accepted. However, risk factors predicting the presence of lymph node metastasis have not been fully investigated. To determine the criteria for local excision of c...

journal_title：Annals of surgical oncology

authors： Adachi Y,Yasuda K,Kakisako K,Sato K,Shiraishi N,Kitano S

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Studies assessing outcomes in occult breast cancer have often included women treated before the routine use of magnetic resonance imaging (MRI). This study examined outcomes for patients presenting with axillary adenopathy and no primary breast tumor detectable by MRI or other imaging methods. METHODS:All p...

journal_title：Annals of surgical oncology

authors： McCartan DP,Zabor EC,Morrow M,Van Zee KJ,El-Tamer MB

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:In 2007, the National Quality Forum (NQF) released four performance measures for the treatment of breast cancer. We proposed to study the degree of adherence with these measures among participating institutions in a multi-institutional trial. METHODS:American College of Surgeons Oncology Group (ACOSOG) Z001...

journal_title：Annals of surgical oncology

authors： Wilke LG,Ballman KV,McCall LM,Giuliano AE,Whitworth PW,Blumencranz PW,Reintgen DS,Burak WE,Leitch AM,Hunt KK

更新日期：2010-08-01 00:00:00