Preoperative u-PAR gene expression in bone marrow indicates the potential power of recurrence in breast cancer cases.

abstract：BACKGROUND:The role neoadjuvant chemoradiotherapy (nCRT) plays in oncological outcomes in early T-stage rectal cancer is uncertain. The present work aims to clarify prognostic outcomes by estimating the effect of nCRT on tumor recurrence prior to major surgery compared with major surgery alone. PATIENTS AND METHODS:Pr...

journal_title：Annals of surgical oncology

authors： Hayes IP,Milanzi E,Gibbs P,Reece JC

更新日期：2020-05-01 00:00:00

abstract：: ...

journal_title：Annals of surgical oncology

authors： Yasui W

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:The inability to visualize the patient and surgical site directly, limits the use of current near infrared fluorescence-guided surgery systems for real-time sentinel lymph node biopsy and tumor margin assessment. METHODS:We evaluated an optical see-through goggle augmented imaging and navigation system (GAI...

journal_title：Annals of surgical oncology

authors： Mondal SB,Gao S,Zhu N,Habimana-Griffin L,Akers WJ,Liang R,Gruev V,Margenthaler J,Achilefu S

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Isolated hepatic perfusion (IHP) of chemotherapy has been proposed to deliver high doses of drug while avoiding systemic toxicity. Hypotonic cisplatin has a high in vitro activity on human colon cancer cells. We studied the safety of a 30-min hypoxic single-pass IHP with hypotonic cisplatin. METHODS:A preli...

journal_title：Annals of surgical oncology

authors： Ortega-Deballon P,Facy O,Consolo D,Magnin G,Tixier H,Simonet M,Rat P,Chauffert B

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:High-grade (HG) mucinous appendiceal neoplasms (MAN) have a worse prognosis than low-grade histology. Our objective was to assess the safety and efficacy of cytoreductive surgery with hyperthermic intraperitoneal chemoperfusion (CRS/HIPEC) in patients with high-grade, high-volume (HG-HV) peritoneal metastase...

journal_title：Annals of surgical oncology

authors： Polanco PM,Ding Y,Knox JM,Ramalingam L,Jones H,Hogg ME,Zureikat AH,Holtzman MP,Pingpank J,Ahrendt S,Zeh HJ,Bartlett DL,Choudry HA

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Despite decreasing rates of subsequent contralateral breast cancer after diagnosis of unilateral primary breast cancer, the proportion of patients electing contralateral prophylactic mastectomy (CPM) is increasing. Our aim was to identify risk factors associated with the identification of occult malignancy (...

journal_title：Annals of surgical oncology

authors： Erdahl LM,Boughey JC,Hoskin TL,Degnim AC,Hieken TJ

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Metaplastic breast cancer (MBC) is characterized by various combinations of adenocarcinoma, mesenchymal, and other epithelial components. It was officially recognized as a distinct pathologic diagnosis in 2000. With few published reports, we hypothesized that MBC may have markedly different characteristics a...

journal_title：Annals of surgical oncology

authors： Pezzi CM,Patel-Parekh L,Cole K,Franko J,Klimberg VS,Bland K

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy in terms of local control (LC) of 24 h infusion of gemcitabine plus radiotherapy after surgery for pancreatic cancer. METHODS:Weekly gemcitabine (100 mg/m(2)) was provided as a 24-hour infusion during the course of radiotherapy (50.4 Gy to the tumor, 39.6 Gy to the nodes). Patients sub...

journal_title：Annals of surgical oncology

authors： Mattiucci GC,Ippolito E,D'Agostino GR,Alfieri S,Antinori A,Crucitti A,Balducci M,Deodato F,Luzi S,Macchia G,Smaniotto D,Morganti AG,Valentini V

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:The goal of this study was to investigate clinical manifestations of lower extremity edema (LEE) after lymph node dissection in patients with primary endometrial cancer. METHODS:Women with primary endometrial cancer who underwent staging surgery between November 2001 and March 2011 were included in the study. ...

journal_title：Annals of surgical oncology

authors： Bae HS,Lim MC,Lee JS,Lee Y,Nam BH,Seo SS,Kang S,Chung SH,Kim JY,Park SY

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:We investigated the relationship between pathologic T-stage and mesorectal metastases after preoperative chemoradiotherapy (CRT) for clinical stage II to III rectal carcinoma. METHODS:The records of consecutive patients with clinical stage II to III carcinoma of the mid or low rectum who underwent surgery a...

journal_title：Annals of surgical oncology

authors： Pucciarelli S,Capirci C,Emanuele U,Toppan P,Friso ML,Pennelli GM,Crepaldi G,Pasetto L,Nitti D,Lise M

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:For some types of cancer, postoperative complications can negatively influence survival, but the association between these complications and oncological outcomes is unclear for patients with esophageal cancer who receive preoperative treatments. METHODS:Data were retrospectively analyzed for patients who un...

journal_title：Annals of surgical oncology

authors： Yamashita K,Makino T,Miyata H,Miyazaki Y,Takahashi T,Kurokawa Y,Yamasaki M,Nakajima K,Takiguchi S,Mori M,Doki Y

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemoperfusion (HIPEC) is routinely used to treat certain peritoneal carcinomatoses (PC), but it can be associated with relatively high complication rates, prolonged hospital length of stay, and potential mortality. Our objective was to determine ...

journal_title：Annals of surgical oncology

authors： Polanco PM,Ding Y,Knox JM,Ramalingam L,Jones H,Hogg ME,Zureikat AH,Holtzman MP,Pingpank J,Ahrendt S,Zeh HJ,Bartlett DL,Choudry HA

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Circulating ('blood-borne') tissue factor (TF) is implicated in the pathogenesis of several chronic conditions, most notably cardiovascular disease, diabetes, and cancer. Full-length TF is an integral membrane protein, while alternatively spliced TF (asTF) can be secreted and, owing to its unique C-terminus,...

journal_title：Annals of surgical oncology

authors： Unruh D,Sagin F,Adam M,Van Dreden P,Woodhams BJ,Hart K,Lindsell CJ,Ahmad SA,Bogdanov VY

更新日期：2015-12-01 00:00:00

abstract：INTRODUCTION:Regional nodal status is the most powerful predictor of recurrence and survival in women with breast cancer. Lymphatic mapping and sentinel lymph node (SLN) biopsy have been found to accurately predict the regional nodal status. Preoperative lymphoscintigraphy has been used in melanoma patients to identify...

journal_title：Annals of surgical oncology

authors： Dupont EL,Kamath VJ,Ramnath EM,Shivers SC,Cox C,Berman C,Leight GS Jr,Ross MI,Blumencranz P,Reintgen DS,DOD Breast Lymphatic Mapping Trial Investigators.

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Long interspersed nuclear element-1 (LINE-1) methylation status, representing global DNA methylation levels, is associated with patient prognosis in several types of cancer. This study was designed to examine the prognostic significance of LINE-1 methylation in patients with hepatocellular carcinoma (HCC) an...

journal_title：Annals of surgical oncology

authors： Zhu C,Utsunomiya T,Ikemoto T,Yamada S,Morine Y,Imura S,Arakawa Y,Takasu C,Ishikawa D,Imoto I,Shimada M

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:The combination of neoadjuvant radiochemotherapy and parenchyma-preserving sleeve resection for lung cancer remains controversial because of potentially increased rate of anastomotic breakdown. We analyzed the effects of applying a decellularized human dermis transplant seeded with autologous fibroblasts in ...

journal_title：Annals of surgical oncology

authors： Roessner E,Vitacolonna M,Schulmeister A,Pilz L,Tsagogiorgas C,Brockmann M,Hohenberger P

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:The use of routine CT imaging for surveillance in asymptomatic patients with cutaneous melanoma is controversial. We report our experience using a surveillance strategy that included CT imaging for a cohort of patients with high-risk melanoma. METHODS:A total of 466 patients with high-risk cutaneous melanom...

journal_title：Annals of surgical oncology

authors： Park TS,Phan GQ,Yang JC,Kammula U,Hughes MS,Trebska-McGowan K,Morton KE,White DE,Rosenberg SA,Sherry RM

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:This multicenter analysis evaluated patient outcome and clinical pathologic features of thymic epithelial tumors after complete surgical resection and adjuvant treatment. METHODS:Histologic classification and clinical staging were performed according to WHO classification and Masaoka staging system, respect...

journal_title：Annals of surgical oncology

authors： Genestreti G,Ampollini L,Burgio MA,Rolli L,Sanna S,Scarpi E,Monti M,Burgio SL,Giannone L,Santo A,Mezzetti M,Casanova C,Buosi R,Rusca M,Amadori D,Gavelli G

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Sentinel lymph node (SLN) mapping techniques have been validated in breast cancer and melanoma. This study summarizes our experience with SLN mapping for colon cancer. METHODS:Fifty-five patients with colon cancer underwent intraoperative SLN mapping. One mL of 1% isosulfan blue was injected subserosally ar...

journal_title：Annals of surgical oncology

authors： Paramo JC,Summerall J,Poppiti R,Mesko TW

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:International consensus criteria (ICC) have redefined borderline resectability for pancreatic ductal adenocarcinoma (PDAC) according to three dimensions: anatomical (BR-A), biological (BR-B), and conditional (BR-C). The present definition acknowledges that resectability is not just about the anatomic relatio...

journal_title：Annals of surgical oncology

authors： Anger F,Döring A,van Dam J,Lock JF,Klein I,Bittrich M,Germer CT,Wiegering A,Kunzmann V,van Eijck C,Löb S

更新日期：2020-09-12 00:00:00

abstract：BACKGROUND:Since its introduction, the sentinel lymph node biopsy (SLNB) has become the standard staging procedure in clinical node-negative melanoma patients. A negative SLNB, however, does not guarantee a recurrence-free survival. Insight into metastatic patterns and risk factors for recurrence in SLNB negative melan...

journal_title：Annals of surgical oncology

authors： Faut M,Wevers KP,van Ginkel RJ,Diercks GF,Hoekstra HJ,Kruijff S,Been LB,van Leeuwen BL

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Racial disparities in outcomes have been documented among patients with esophageal cancer. The purpose of this study is to identify mechanisms for ethnicity/race-related differences in the use of cancer-directed surgery and mortality. METHODS:Data from the Surveillance, Epidemiology and End Results (SEER) p...

journal_title：Annals of surgical oncology

authors： Revels SL,Morris AM,Reddy RM,Akateh C,Wong SL

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Liver kinase B1 (LKB1) loss by gene mutation, loss of heterozygosity, and promoter methylation rarely occurs in colorectal cancer. We wondered whether LKB1 loss could be deregulated at the transcriptional level to promote tumor progression and poor outcome in colorectal cancer. METHODS:Mechanistic studies w...

journal_title：Annals of surgical oncology

authors： He TY,Tsai LH,Huang CC,Chou MC,Lee H

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Seed localization uses a radioactive source to identify nonpalpable breast lesions for excision; it is an emerging alternative to wire localization (WL). Previous single health system studies report decreased rates of re-excision and improved patient convenience with this technique. This study is the first t...

journal_title：Annals of surgical oncology

authors： Rao R,Moldrem A,Sarode V,White J,Amen M,Rao M,Andrews V,Euhus D,Radford L,Ulissey M

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:The involvement of lipids in carcinogenic and developmental processes has been reported in some malignancies, but their roles in gastric cancer remain to be analyzed. In this study, we compared the lipid content of gastric cancer tissue and adjacent nonneoplastic mucosa using imaging mass spectrometry. METH...

journal_title：Annals of surgical oncology

authors： Uehara T,Kikuchi H,Miyazaki S,Iino I,Setoguchi T,Hiramatsu Y,Ohta M,Kamiya K,Morita Y,Tanaka H,Baba S,Hayasaka T,Setou M,Konno H

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The traditional Billroth II and Roux-en-Y anastomosis after laparoscopic distal gastrectomy for gastric cancer are associated with bile reflux gastritis and roux stasis syndrome, respectively. The uncut Roux-en-Y gastrojejunostomy can decrease the incidence of these complications by blocking the entry of bil...

journal_title：Annals of surgical oncology

authors： Wang J,Wang Q,Dong J,Yang K,Ji S,Fan Y,Wang C,Ma Q,Wei Q,Ji G

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Recent data suggest sentinel lymph node biopsy (SLNBx) for invasive breast cancer (IBC) is widely performed in the United States, often outside of a clinical trial. We sought to describe SLNBx practice patterns in Canada, as well as criteria for abandonment of concurrent axillary lymph node dissection. METH...

journal_title：Annals of surgical oncology

authors： Porter GA,McMulkin H,Lovrics PJ

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:The prospective Neoadjuvant Breast Symphony Trial (NBRST) study found that MammaPrint/BluePrint functional molecular subtype is superior to conventional immunohistochemistry/fluorescence in situ hybridization subtyping for predicting pathologic complete response (pCR) to neoadjuvant chemotherapy. The purpose...

journal_title：Annals of surgical oncology

authors： Baron P,Beitsch P,Boselli D,Symanowski J,Pellicane JV,Beatty J,Richards P,Mislowsky A,Nash C,Lee LA,Murray M,de Snoo FA,Stork-Sloots L,Gittleman M,Akbari S,Whitworth P

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Despite a growing body of literature on oncologic and reconstructive outcomes after total skin-sparing mastectomy (TSSM), some questions related to this approach remain unanswered, including strategies for managing tumor involvement of the nipple while maintaining the aesthetic benefits of TSSM. METHODS:A p...

journal_title：Annals of surgical oncology

authors： Amara D,Peled AW,Wang F,Ewing CA,Alvarado M,Esserman LJ

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:The prognosis for patients with locally advanced thoracic esophageal cancer is extremely unfavorable. We have been administering neoadjuvant chemoradiotherapy (CRT) followed by esophagectomy to these patients and studying whether REG I expression in untreated endoscopic biopsy specimens is predictive of pati...

journal_title：Annals of surgical oncology

authors： Motoyama S,Sugiyama T,Ueno Y,Okamoto H,Takasawa S,Nanjo H,Watanabe H,Maruyama K,Okuyama M,Ogawa J

更新日期：2006-12-01 00:00:00