A novel therapeutic combination sequentially targeting aurora B and Bcl-xL in hepatocellular carcinoma.

abstract：BACKGROUND:To investigate the efficacy and safety of adding continuous occlusion of hepatic artery proper to intermittent Pringle maneuver in partial hepatectomy for ruptured hepatocellular carcinoma. MATERIALS AND METHODS:This is a retrospective study on data that were prospectively collected and entered into a compu...

journal_title：Annals of surgical oncology

authors： Xia F,Lau WY,Qian C,Ma K,Li X,Bie P

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:Rates of both unilateral (UM) and contralateral prophylactic mastectomy (CPM) for unilateral early-stage breast cancer (ESBC) have been increasing since 2003. Recent studies suggest that this increase may be due to women choosing UM and CPM because of fear. We conducted an in-depth qualitative study to identify...

journal_title：Annals of surgical oncology

authors： Covelli AM,Baxter NN,Fitch MI,McCready DR,Wright FC

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Attention has been focused on attempts to eliminate breast surgery for breast cancer patients who achieve a pathologic complete response after neoadjuvant chemotherapy (NAC). However, there are few data on ipsilateral breast tumor recurrence (IBTR) among patients with triple-negative or epidermal growth fact...

journal_title：Annals of surgical oncology

authors： Ishitobi M,Matsuda N,Tazo M,Nakayama S,Tokui R,Ogawa T,Yoshida A,Kojima Y,Kuwayama T,Nakayama T,Yamauchi H,Nakamura S,Tsugawa K,Hayashi N

更新日期：2020-10-06 00:00:00

abstract：BACKGROUND:Women considering risk reduction surgery after a diagnosis of breast/ovarian cancer and/or inherited cancer gene mutation face difficult decisions. The safety of combined breast and gynecologic surgery has not been well studied; therefore, we evaluated the outcomes for patients who have undergone coordinated...

journal_title：Annals of surgical oncology

authors： Ma IT,Gray RJ,Wasif N,Butler KA,Cornella JL,Magrina JF,Magtibay PM,Casey WJ,Mahabir R,Rebecca AM,Hunt KS,Pockaj BA

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:In the Netherlands, a maximum waiting time from diagnosis to treatment (WT) of 5 weeks is recommended for curative cancer treatment. This study aimed to evaluate the association between WT and overall survival (OS) in patients undergoing gastrectomy for cancer. METHODS:This nationwide study included data fr...

journal_title：Annals of surgical oncology

authors： Brenkman HJF,Visser E,van Rossum PSN,Siesling S,van Hillegersberg R,Ruurda JP

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:The added value of surgery in breast cancer patients with pathological complete response (pCR) after neoadjuvant systemic therapy (NST) is uncertain. The accuracy of imaging identifying pCR for omission of surgery, however, is insufficient. We investigated the accuracy of ultrasound-guided biopsies identifyi...

journal_title：Annals of surgical oncology

authors： van Loevezijn AA,van der Noordaa MEM,van Werkhoven ED,Loo CE,Winter-Warnars GAO,Wiersma T,van de Vijver KK,Groen EJ,Blanken-Peeters CFJM,Zonneveld BJGL,Sonke GS,van Duijnhoven FH,Vrancken Peeters MTFD

更新日期：2020-12-02 00:00:00

abstract：PURPOSE:Unilateral mastectomy (UM) and contralateral prophylactic mastectomy (CPM) for early-stage breast cancer (ESBC) have been increasing. Numerous etiological factors for this rise have been suggested, including increasing use of magnetic resonance imaging (MRI) and reconstruction, surgeon's preference, and patient...

journal_title：Annals of surgical oncology

authors： Covelli AM,Baxter NN,Fitch MI,Wright FC

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to examine the frequency, pattern, and predictive factors associated with occult level II lymph node (LN) metastases in papillary thyroid carcinoma (PTC) patients with clinically metastatic lymph nodes in the lateral neck (level III, IV, and/or V) by preoperative ultrasonography...

journal_title：Annals of surgical oncology

authors： Koo BS,Seo ST,Lee GH,Kim JM,Choi EC,Lim YC

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Little is known about complications after major duodenopancreatic surgery for duodenopancreatic neuroendocrine tumors (dpNETs) in multiple endocrine neoplasia type 1 (MEN1). Therefore, the incidence and severity of complications after major surgery for MEN1-related dpNETs were assessed. METHODS:Patients wer...

journal_title：Annals of surgical oncology

authors： van Beek DJ,Nell S,Vorselaars WMCM,Bonsing BA,van Eijck CHJ,van Goor H,Nieveen van Dijkum EJ,Dejong CHC,Valk GD,DutchMEN Study Group (DMSG).,Borel Rinkes IHM,Vriens MR

更新日期：2021-01-31 00:00:00

abstract：BACKGROUND:Clinical practice guidelines have been developed to improve melanoma patient care. However, it is unclear whether failure to comply with these standards (either excessive or inadequate treatment) increases morbidity or relapse rates. Therefore, we undertook this study to evaluate the effect of variance from ...

journal_title：Annals of surgical oncology

authors： Erickson Foster J,Velasco JM,Hieken TJ

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:The status of the sentinel lymph node is an important predictor for survival in melanoma patients, but it is still unclear if early removal of micrometastases by sentinel lymph node dissection (SLND) alters survival. A large series of melanoma patients from a single center with long-term follow-up was analyz...

journal_title：Annals of surgical oncology

authors： Satzger I,Meier A,Hoy L,Völker B,Kapp A,Hauschild A,Gutzmer R

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Recurrent laryngeal nerve (RLN) injury is a rare complication for patients undergoing neck exploration for primary hyperparathyroidism (pHPT). Distances between RLNs and parathyroid adenomas have not been previously published. In this study we used a RLN monitor to identify the RLN and to measure the proximi...

journal_title：Annals of surgical oncology

authors： Untch BR,Adam MA,Danko ME,Barfield ME,Dixit D,Scheri RP,Olson JA

更新日期：2012-11-01 00:00:00

abstract：PURPOSE:To ensure a surgical margin of ≥1 cm for the effective treatment of phyllodes tumors of the breast (PTB) a second resection has been recommended, but the outcomes of an extensive series of cases employing the aforementioned criterion cast doubt on this clinical approach. The aim of this study was to identify th...

journal_title：Annals of surgical oncology

authors： Yom CK,Han W,Kim SW,Park SY,Park IA,Noh DY

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:Patients with locally advanced cervical cancer (LACC) are usually treated with concurrent chemoradiotherapy. Extended-field chemoradiotherapy is indicated in case of para-aortic node involvement at initial assessment. 18-Fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (18-FDG PET/CT) i...

journal_title：Annals of surgical oncology

authors： Leblanc E,Gauthier H,Querleu D,Ferron G,Zerdoud S,Morice P,Uzan C,Lumbroso S,Lecuru F,Bats AS,Ghazzar N,Bannier M,Houvenaeghel G,Brenot-Rossi I,Narducci F

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate whether patient satisfaction, as measured by the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey, is associated with short-term outcomes after major cancer surgery. MATERIALS AND METHODS:We first used national Medicare claims to identi...

journal_title：Annals of surgical oncology

authors： Kaye DR,Richardson CR,Ye Z,Herrel LA,Ellimoottil C,Miller DC

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Sarcopenia, characterized by loss of skeletal muscle mass, is recognized as a prognostic factor in patients with gastric cancer. However, wide variability exists in the cutoff values of muscle mass for defining sarcopenia across previous studies, and the best cutoff values to predict survival remain unknown....

journal_title：Annals of surgical oncology

authors： Nishigori T,Tsunoda S,Obama K,Hisamori S,Hashimoto K,Itatani Y,Okada K,Sakai Y

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Given the emerging evidence supporting the lack of prognostic significance of gross extrathyroidal extension invading only strap muscles (strap-gETE), this study investigated whether lobectomy is feasible for patients with strap-gETE. METHODS:A retrospective cohort study was conducted with 636 patients who ...

journal_title：Annals of surgical oncology

authors： Song E,Kim WW,Jeon MJ,Sung TY,Song DE,Kim TY,Chung KW,Kim WB,Shong YK,Hong SJ,Lee YM,Kim WG

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Bowel function in long-term rectal cancer survivors with anastomosis has not been characterized adequately. We hypothesized that bowel function is associated with patient, disease, and treatment characteristics. METHODS:The cohort study included Kaiser Permanente members who were long-term (≥5 years) rectal...

journal_title：Annals of surgical oncology

authors： Alavi M,Wendel CS,Krouse RS,Temple L,Hornbrook MC,Bulkley JE,McMullen CK,Grant M,Herrinton LJ

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Residual tumor size after neoadjuvant chemotherapy is an important consideration in surgical planning. We examined the accuracy of the combination of mammography and sonography in predicting pathologic residual tumor size. METHODS:Tumor size was evaluated by physical examination, mammography, and sonography...

journal_title：Annals of surgical oncology

authors： Peintinger F,Kuerer HM,Anderson K,Boughey JC,Meric-Bernstam F,Singletary SE,Hunt KK,Whitman GJ,Stephens T,Buzdar AU,Green MC,Symmans WF

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:A recent study showed that circulating exosomal PD-L1 is an effective predictor for anti-PD-1 therapy in melanomas. Exosomal PD-L1 induced immunosuppression microenvironments in cancer patients. However, its prognostic value and immunosuppressive effect in gastric cancer (GC) were poorly understood. METHODS...

journal_title：Annals of surgical oncology

authors： Fan Y,Che X,Qu J,Hou K,Wen T,Li Z,Li C,Wang S,Xu L,Liu Y,Qu X

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Although often proposed as a means to reduce the harmful consequences of tumor spill, water lavage has yet to be systematically evaluated in relevant in vitro and in vivo models. This study evaluates the mechanisms and utility of a single water lavage to improve the sequelae of tumor spill during laparotomy....

journal_title：Annals of surgical oncology

authors： Ito F,Camoriano M,Seshadri M,Evans SS,Kane JM 3rd,Skitzki JJ

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Abnormal phosphatase and tensin analog (PTEN) gene expression has been noted in neoplasms. The PTEN protein cleaves phosphate groups from cellular growth kinases, inhibiting tumor propagation. A downstream target of PTEN is AKT, a serine-threonine kinase that when activated inhibits apoptosis. We sought to d...

journal_title：Annals of surgical oncology

authors： Mohiuddin I,Cao X,Ozvaran MK,Zumstein L,Chada S,Smythe WR

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:18-F-fluorodeoxyglucose positron emission tomography (FDG-PET) is valuable in staging of esophageal cancer. However, FDG-PET may falsely upstage patients leading to incorrect exclusion from surgical treatment. This study was performed to determine the false-positive rate and possible causes. METHODS:The rat...

journal_title：Annals of surgical oncology

authors： van Westreenen HL,Heeren PA,Jager PL,van Dullemen HM,Groen H,Plukker JT

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Arginine plays a pivotal role in regulating ureagenesis, polyamine biosynthesis, and nitric oxide production, metabolic pathways that may be stimulated in the liver of the tumor-bearing host. Normally, plasma arginine is excluded from the hepatocyte intracellular space by the low basal activity of its membra...

journal_title：Annals of surgical oncology

authors： Espat NJ,Copeland EM,Souba WW

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Modified Appleby procedure could be indicated in stage III locally advanced body pancreatic ductal adenocarcinoma (PDAC) involving the celiac axis after neoadjuvant treatment. PATIENTS AND METHODS:We report the case of a 38-year-old woman presenting a tumor arising from the body of the pancreas, involving t...

journal_title：Annals of surgical oncology

authors： Triki H,Bergeat D,Bougard M,Robin F,Sulpice L

更新日期：2020-10-21 00:00:00

abstract：BACKGROUND:Pseudoangiomatous stromal hyperplasia (PASH) is a benign localized fibrotic lesion in which clusters of spindle cells form cleftlike spaces, resembling ectatic vessels. Its relationship to breast cancer risk has not been characterized. MATERIALS AND METHODS:Histological presence of PASH was evaluated by rev...

journal_title：Annals of surgical oncology

authors： Degnim AC,Frost MH,Radisky DC,Anderson SS,Vierkant RA,Boughey JC,Pankratz VS,Ghosh K,Hartmann LC,Visscher DW

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Occult breast cancer (OBC) is a rare clinical entity. Current surgical management includes axillary lymphadenectomy (ALND) with or without mastectomy. We sought to investigate the role of sentinel lymph node biopsy (SLNB) in patients with OBC treated with neoadjuvant chemotherapy (NAC). METHODS:Patients wit...

journal_title：Annals of surgical oncology

authors： Cohen BL,Collier AL,Kelly KN,Goel N,Kesmodel SB,Yakoub D,Moller M,Avisar E,Franceschi D,Macedo FI

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Peritoneal metastasis of colonic origin is associated with a poor prognosis. This study aimed to analyze the clinicopathologic characteristics and prognostic predictors of survival in a cohort of patients treated with cytoreductive surgery (CRS) and perioperative intraperitoneal chemotherapy (POIC) during tw...

journal_title：Annals of surgical oncology

authors： Ihemelandu C,Sugarbaker PH

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Granulomatous mastitis is an uncommon chronic inflammatory breast condition that is characterized by granulomatous inflammation. Granulomatous mastitis presents a challenging clinical scenario, because it can mimic carcinoma. The etiology and optimal treatment remain unclear. We report our experience with gr...

journal_title：Annals of surgical oncology

authors： Joseph KA,Luu X,Mor A

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:To analyze the relationship of objective and subjective evaluation tools of breast aesthetics, we compare the results of the BCCT.core (breast cancer conservative treatment.cosmetic results) software, a semiautomated objective symmetry evaluation tool, with those of the Aesthetic Status of the BCTOS (Breast ...

journal_title：Annals of surgical oncology

authors： Heil J,Dahlkamp J,Golatta M,Rom J,Domschke C,Rauch G,Cardoso MJ,Sohn C

更新日期：2011-01-01 00:00:00