当前位置： SCI文献检索 > ANNALS OF SURGICAL ONCOLOGY期刊下所有文献 > Predictors of Bowel Function in Long-term Rectal Cancer Survivors with Anastomosis.

Predictors of Bowel Function in Long-term Rectal Cancer Survivors with Anastomosis.

Abstract：

BACKGROUND:Bowel function in long-term rectal cancer survivors with anastomosis has not been characterized adequately. We hypothesized that bowel function is associated with patient, disease, and treatment characteristics. METHODS:The cohort study included Kaiser Permanente members who were long-term (≥5 years) rectal cancer survivors with anastomosis. Bowel function was scored using the self-administered, 14-item Memorial Sloan-Kettering Cancer Center Bowel Function Index. Patient, cancer, and treatment variables were collected from the electronic medical chart. We used multiple regression to assess the relationship of patient- and treatment-related variables with the bowel function score. RESULTS:The study included 381 anastomosis patients surveyed an average 12 years after their rectal cancer surgeries. The total bowel function score averaged 53 (standard deviation, 9; range, 31-70, higher scores represent better function). Independent factors associated with worse total bowel function score included receipt of radiation therapy (yes vs. no: 5.3-unit decrement, p < 0.0001), tumor distance from the anal verge (≤6 cm vs. >6 cm: 3.2-unit decrement, p < 0.01), and history of a temporary ostomy (yes vs. no: 4.0-unit decrement, p < 0.01). One factor measured at time of survey was also associated with worse total bowel function score: ever smoking (2.3-unit decrement, p < 0.05). The regression model explained 20% of the variation in the total bowel function score. CONCLUSIONS:Low tumor location, radiation therapy, temporary ostomy during initial treatment, and history of smoking were linked with decreased long-term bowel function following an anastomosis. These results should improve decision-making about surgical options.

journal_name

Ann Surg Oncol

journal_title

Annals of surgical oncology

authors

Alavi M,Wendel CS,Krouse RS,Temple L,Hornbrook MC,Bulkley JE,McMullen CK,Grant M,Herrinton LJ

doi

10.1245/s10434-017-6017-x

subject

Has Abstract

pub_date

2017-11-01 00:00:00

pages

3596-3603

issue

12

eissn

1068-9265

issn

1534-4681

pii

10.1245/s10434-017-6017-x

journal_volume

24

pub_type

杂志文章

相关文献

ANNALS OF SURGICAL ONCOLOGY文献大全
  • Role of Sentinel Lymph Node Biopsy in Microinvasive Breast Cancer.

    abstract：BACKGROUND:Microinvasive ductal carcinoma (DCISM), defined as DCIS with a focus of invasive carcinoma ≤ 1 mm, can be managed similarly to pure DCIS; however, management of the axilla in DCISM has been a subject of debate. Reports in the literature differ on the utility and necessity of sentinel lymph node biopsy (SLNB)...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-020-08606-3

    authors： Fan B,Pardo JA,Serres S,Alapati AC,Szewczyk J,Mele A,James TA

    更新日期：2020-10-01 00:00:00

  • Prevention of anastomotic leakage after total gastrectomy with perioperative supplemental oxygen administration: a prospective randomized, double-blind, controlled, single-center trial.

    abstract：BACKGROUND:The role of supplemental oxygen therapy in the healing of esophagojejunal anastomosis is still very much in an experimental stage. The aim of the present prospective, randomized study was to assess the effect of administration of perioperative supplemental oxygen therapy on esophagojejunal anastomosis, where...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,随机对照试验

    doi：10.1245/s10434-012-2714-7

    authors： Schietroma M,Cecilia EM,Carlei F,Sista F,De Santis G,Piccione F,Amicucci G

    更新日期：2013-05-01 00:00:00

  • Postoperative Infectious Complications are Associated with Adverse Oncologic Outcomes in Esophageal Cancer Patients Undergoing Preoperative Chemotherapy.

    abstract：BACKGROUND:For some types of cancer, postoperative complications can negatively influence survival, but the association between these complications and oncological outcomes is unclear for patients with esophageal cancer who receive preoperative treatments. METHODS:Data were retrospectively analyzed for patients who un...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-015-5045-7

    authors： Yamashita K,Makino T,Miyata H,Miyazaki Y,Takahashi T,Kurokawa Y,Yamasaki M,Nakajima K,Takiguchi S,Mori M,Doki Y

    更新日期：2016-06-01 00:00:00

  • Radiation Therapy is Independently Associated with Worse Survival After R0-Resection for Stage I-II Non-small Cell Lung Cancer: An Analysis of the National Cancer Data Base.

    abstract：BACKGROUND:The 1998 post-operative radiotherapy meta-analysis for lung cancer showed a survival detriment associated with radiation for stage I-II resected non-small cell lung cancer (NSCLC), but has been criticized for including antiquated radiation techniques. We analyzed the National Cancer Database (NCDB) to determ...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-017-5786-6

    authors： Pezzi TA,Mohamed AS,Fuller CD,Blanchard P,Pezzi C,Sepesi B,Hahn SM,Gomez DR,Chun SG

    更新日期：2017-05-01 00:00:00

  • Disseminated peritoneal adenomucinosis: a critical review.

    abstract：BACKGROUND:The term pseudomyxoma peritonei has been used in reference to any condition, benign or malignant, in which the peritoneal cavity becomes filled with a gelatinous substance. The term is nonspecific and does not denote therapeutic or prognostic significance. Controversy centers around which patients benefit fr...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,评审

    doi：10.1007/s10434-999-0797-6

    authors： Wirtzfeld DA,Rodriguez-Bigas M,Weber T,Petrelli NJ

    更新日期：1999-12-01 00:00:00

  • Extraskeletal Myxoid Chondrosarcoma with Molecularly Confirmed Diagnosis: A Multicenter Retrospective Study Within the Italian Sarcoma Group.

    abstract：BACKGROUND:Extraskeletal myxoid chondrosarcoma (EMC) is a rare sarcoma of uncertain origin, marked by specific chromosomal translocations involving the NR4A3 gene, and usually characterized by an indolent course. Surgery (with or without radiotherapy) is the treatment of choice in localized disease. The treatment for a...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-020-08737-7

    authors： Paioli A,Stacchiotti S,Campanacci D,Palmerini E,Frezza AM,Longhi A,Radaelli S,Donati DM,Beltrami G,Bianchi G,Barisella M,Righi A,Benini S,Fiore M,Picci P,Gronchi A

    更新日期：2021-02-01 00:00:00

  • Sestamibi imaging for primary hyperparathyroidism: the impact of surgeon interpretation and radiologist volume.

    abstract：BACKGROUND:Preoperative localization is the first step towards minimally invasive targeted parathyroidectomy. While there are data emphasizing that surgeon experience optimizes operative outcomes, the role of the radiologist's experience in successful preoperative imaging is unclear. We hypothesized that the accuracy o...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-012-2581-2

    authors： Zia S,Sippel RS,Chen H

    更新日期：2012-11-01 00:00:00

  • Extramammary Paget's disease in males: survival outcomes in 495 patients.

    abstract：BACKGROUND:Extramammary Paget's disease (EMPD) is a rare intraepithelial malignancy with poorly described outcomes. EMPD in men is primarily found in the perianal and penoscrotal areas. We assessed incidence and time trends of EMPD in men as well as extent and predictors of survival using the Surveillance, Epidemiology...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-014-4139-y

    authors： Herrel LA,Weiss AD,Goodman M,Johnson TV,Osunkoya AO,Delman KA,Master VA

    更新日期：2015-05-01 00:00:00

  • Long-term outcomes in patients with calciphylaxis from hyperparathyroidism.

    abstract：BACKGROUND:Calciphylaxis is a rare condition associated with chronic renal failure and entails a very poor prognosis. Pathogenesis is poorly understood but involves abnormalities in calcium and phosphorus metabolism that lead to vascular and extravascular calcification. Patients present with painful ulcerating plaques ...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/ASO.2006.03.042

    authors： Duffy A,Schurr M,Warner T,Chen H

    更新日期：2006-01-01 00:00:00

  • Comparison of survival of patients with BCLC stage A hepatocellular carcinoma after hepatic resection or transarterial chemoembolization: a propensity score-based analysis.

    abstract：BACKGROUND:It is unclear whether hepatic resection (HR) or transarterial chemoembolization (TACE) is associated with better outcomes for patients with hepatocellular carcinoma (HCC) in Barcelona Clinic Liver Cancer (BCLC) stage A. The present study compared survival for patients with BCLC stage A HCC treated by HR or T...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-014-3704-8

    authors： Guo Z,Zhong JH,Jiang JH,Zhang J,Xiang BD,Li LQ

    更新日期：2014-09-01 00:00:00

  • Extrahepatic bile duct adenocarcinoma: patients at high-risk for local recurrence treated with surgery and adjuvant chemoradiation have an equivalent overall survival to patients with standard-risk treated with surgery alone.

    abstract：BACKGROUND:Patients with resected extrahepatic bile duct adenocarcinoma who have microscopically positive resection margins and/or pathologic locoregional nodal involvement (R1pN1) have a high-risk of locoregional recurrence, and therefore, we advocate the use of adjuvant chemoradiation. To evaluate the safety and effe...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-008-9998-7

    authors： Borghero Y,Crane CH,Szklaruk J,Oyarzo M,Curley S,Pisters PW,Evans D,Abdalla EK,Thomas MB,Das P,Wistuba II,Krishnan S,Vauthey JN

    更新日期：2008-11-01 00:00:00

  • Sentinel lymph node mapping for thick (>or=4-mm) melanoma: should we be doing it?

    abstract：BACKGROUND:Thick (>or=4-mm) primary melanomas are believed to be associated with a high incidence of occult distant metastases. The use of sentinel lymph node (SLN) mapping and biopsy in the treatment lesions has been questioned. METHODS:A retrospective review of a computerized database identified 114 patients who und...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/aso.2003.03.055

    authors： Carlson GW,Murray DR,Hestley A,Staley CA,Lyles RH,Cohen C

    更新日期：2003-05-01 00:00:00

  • Impact of an In Situ Component on Outcome After In-Breast Tumor Recurrence in Patients Treated with Breast-Conserving Therapy.

    abstract：BACKGROUND:Among all in-breast tumor recurrences (IBTR) following breast-conserving therapy (BCT), some comprise metachronous new primaries (NPs) while others are true recurrences (TRs). Establishing this distinction remains a challenge. METHODS:We studied 3932 women who underwent BCT for stage I-III breast cancer fro...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-017-6209-4

    authors： Laird J,Lok B,Siu C,Cahlon O,Khan AJ,McCormick B,Powell SN,Cody H,Wen HY,Ho A,Braunstein LZ

    更新日期：2018-01-01 00:00:00

  • Prognostic effect of lymph node micrometastasis in patients with histologically node-negative gastric cancer.

    abstract：BACKGROUND:There is no consensus as to the impact of lymph node micrometastasis on survival of patients with gastric cancer. The aim of this study was to clarify the prognostic significance of lymph node micrometastasis in patients with histologically node-negative gastric cancer. METHODS:Lymph nodes (n = 2039) from 6...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1007/BF02574499

    authors： Yasuda K,Adachi Y,Shiraishi N,Inomata M,Takeuchi H,Kitano S

    更新日期：2002-10-01 00:00:00

  • Impact of Radical Hysterectomy Versus Simple Hysterectomy on Survival of Patients with Stage 2 Endometrial Cancer: A Meta-analysis.

    abstract：BACKGROUND:The strategy of radical surgery for stage 2 endometrial cancer (EC) remains controversial. This meta-analysis aimed to investigate the impact of radical hysterectomy (RH) versus simple hysterectomy (SH) on survival of patients with stage 2 EC. METHODS:A systematic review was conducted to identify studies co...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,meta分析

    doi：10.1245/s10434-019-07472-y

    authors： Liu T,Tu H,Li Y,Liu Z,Liu G,Gu H

    更新日期：2019-09-01 00:00:00

  • A prospective evaluation of palliative outcomes for surgery of advanced malignancies.

    abstract：BACKGROUND:We prospectively evaluated the effectiveness of major surgery in treating symptoms of advanced malignancies. METHODS:Fifty-nine patients were evaluated for major symptoms of intent to treat and were followed up until death or last clinical evaluation. Surgeons identified planned operations before surgery as...

    journal_title：Annals of surgical oncology

    pub_type： 临床试验,杂志文章

    doi：10.1245/aso.2003.06.011

    authors： McCahill LE,Smith DD,Borneman T,Juarez G,Cullinane C,Chu DZ,Ferrell BR,Wagman LD

    更新日期：2003-07-01 00:00:00

  • Unresectable locally advanced pancreatic cancer: a multimodal treatment using neoadjuvant chemoradiotherapy (gemcitabine plus stereotactic radiosurgery) and subsequent surgical exploration.

    abstract：BACKGROUND:Pancreatic cancer accounts for approximately 3% of cancer deaths in Europe. Locally advanced pancreatic cancer (LAPC) involves vascular structures, and resectability is low, with a median survival time of 6 to 11 months. We conducted a prospective, nonrandomized study of patients with LAPC to assess the effe...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-010-1019-y

    authors： Polistina F,Costantin G,Casamassima F,Francescon P,Guglielmi R,Panizzoni G,Febbraro A,Ambrosino G

    更新日期：2010-08-01 00:00:00

  • Prognostic significance of osteopontin expression in human gastric carcinoma.

    abstract：BACKGROUND:Osteopontin (OPN) is a secreted, integrin-binding glycophosphoprotein that has been implicated in the progression of various solid tumors. To evaluate the clinical significance of OPN in gastric carcinoma, we investigated OPN expression in resected tumors. METHODS:Expression of OPN protein by gastric cancer...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-007-9564-8

    authors： Higashiyama M,Ito T,Tanaka E,Shimada Y

    更新日期：2007-12-01 00:00:00

  • Impact of surgical experience on in-hospital complication rates in patients undergoing minimally invasive prostatectomy: a population-based study.

    abstract：BACKGROUND:The relationship between provider volume and complication and transfusion rates in patients undergoing minimally invasive prostatectomy (MIRP) for prostate cancer has not been assessed. Temporal trends in MIRP annual surgical caseload (AC), impact of MIRP surgical experience (SE), and in-hospital complicatio...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-010-1300-0

    authors： Budäus L,Sun M,Abdollah F,Zorn KC,Morgan M,Johal R,Liberman D,Thuret R,Isbarn H,Salomon G,Haese A,Montorsi F,Shariat SF,Perrotte P,Graefen M,Karakiewicz PI

    更新日期：2011-03-01 00:00:00

  • Radiographic Surveillance of Patients with Non-BRCA1/2 Pathogenic Variants.

    abstract：INTRODUCTION:The National Comprehensive Cancer Network (NCCN) developed clinical practice guidelines for germline pathogenic variants in highly penetrant genes, such as TP53 and PTEN, and in moderately penetrant genes, such as CHEK2, ATM and PALB2. Whether the practice of radiographic surveillance of patients with path...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-019-08191-0

    authors： Hudson L,Gower N,Lenarcic S,Trufan SJ,White RL Jr

    更新日期：2020-07-01 00:00:00

  • Messenger RNA expression of vascular endothelial growth factor and its receptors in primary colorectal cancer and corresponding liver metastasis.

    abstract：BACKGROUND:Antiangiogenic therapies have been developed recently in combination with traditional chemotherapy for patients with metastatic colorectal cancer. The aim of this study was to clarify the association between messenger RNA (mRNA) levels of vascular endothelial growth factor (VEGF) and its receptors (VEGFR) in...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-008-9811-7

    authors： Kobayashi H,Sugihara K,Uetake H,Higuchi T,Yasuno M,Enomoto M,Kuramochi H,Lenz HJ,Danenberg KD,Danenberg PV

    更新日期：2008-04-01 00:00:00

  • Tumor-associated antigen expressing Listeria monocytogenes induces effective primary and memory T-cell responses against hepatic colorectal cancer metastases.

    abstract：PURPOSE:Despite advances in therapy for the treatment of metastatic colorectal cancer, many patients die of hepatic disease. Current immunotherapeutic strategies are likely limited by inhibitory signals from the tumor. To successfully eliminate tumor deposits within an organ, an appropriate immunologic milieu to amplif...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-011-2037-0

    authors： Olino K,Wada S,Edil BH,Pan X,Meckel K,Weber W,Slansky J,Tamada K,Lauer P,Brockstedt D,Pardoll D,Schulick R,Yoshimura K

    更新日期：2012-07-01 00:00:00

  • Keynote Address at the American Society of Breast Surgeons 18th Annual Meeting : Current and Future Application of Intraoperative Radiotherapy (IORT) in the Curative and Palliative Treatment of Breast Cancer.

    abstract：:Intraoperative radiotherapy (IORT) is increasingly used worldwide. Breast cancer is the most rapidly growing indication for IORT, approaching 70-80% of cases in most centers. This report reviews the theoretical background and clinical use of IORT for primary and metastasized breast cancer. There are established applic...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-017-5942-z

    authors： Wenz F

    更新日期：2017-10-01 00:00:00

  • ASO Author Reflections: Cytoreduction for Extrahepatic Metastatic Neuroendocrine Tumors.

    abstract：: ...

    journal_title：Annals of surgical oncology

    pub_type： 评论,杂志文章

    doi：10.1245/s10434-018-6885-8

    authors： Chan DL,Hallet J

    更新日期：2018-12-01 00:00:00

  • Follow-Up Recommendations after Diagnosis of Primary Cutaneous Melanoma: A Population-Based Study in New South Wales, Australia.

    abstract：BACKGROUND:Follow-up practices after diagnosis and treatment of primary cutaneous melanoma vary considerably. We aimed to determine factors associated with recommendations for follow-up setting, frequency, skin surveillance, and concordance with clinical guidelines. METHODS:The population-based Melanoma Patterns of Ca...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-017-6319-z

    authors： Read RL,Madronio CM,Cust AE,Goumas C,Watts CG,Menzies S,Curtin AM,Mann G,Thompson JF,Morton RL

    更新日期：2018-03-01 00:00:00

  • Hypoxia in melanoma: using optical spectroscopy and EF5 to assess tumor oxygenation before and during regional chemotherapy for melanoma.

    abstract：BACKGROUND:There is increasing evidence that tumor hypoxia plays a significant role in the chemoresistance of melanoma, but to our knowledge, real-time tumor oxygenation during isolated limb infusion (ILI) has not been studied. We sought to demonstrate the feasibility of measuring real-time alterations in tissue oxygen...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-013-3222-0

    authors： Speicher PJ,Beasley GM,Jiang B,Lidsky ME,Palmer GM,Scarbrough PM,Mosca PJ,Dewhirst MW,Tyler DS

    更新日期：2014-05-01 00:00:00

  • Adherence to the National Quality Forum (NQF) breast cancer measures within cancer clinical trials: a review from ACOSOG Z0010.

    abstract：BACKGROUND:In 2007, the National Quality Forum (NQF) released four performance measures for the treatment of breast cancer. We proposed to study the degree of adherence with these measures among participating institutions in a multi-institutional trial. METHODS:American College of Surgeons Oncology Group (ACOSOG) Z001...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-010-0980-9

    authors： Wilke LG,Ballman KV,McCall LM,Giuliano AE,Whitworth PW,Blumencranz PW,Reintgen DS,Burak WE,Leitch AM,Hunt KK

    更新日期：2010-08-01 00:00:00

  • Restrictive Intraoperative Fluid Therapy is Associated with Decreased Morbidity and Length of Stay Following Hyperthermic Intraperitoneal Chemoperfusion.

    abstract：BACKGROUND:Recent data have demonstrated multiple benefits of intra- and postoperative fluid restriction in major abdominal surgery; however, data regarding the outcomes of fluid restriction in cytoreductive surgery and hyperthermic intraperitoneal chemoperfusion (CRS/HIPEC) are limited. This study evaluates the safety...

    journal_title：Annals of surgical oncology

    pub_type： 临床试验,杂志文章

    doi：10.1245/s10434-018-07092-y

    authors： Hendrix RJ,Damle A,Williams C,Harris A,Spanakis S,Lambert DH,Lambert LA

    更新日期：2019-02-01 00:00:00

  • Surgical approach and perioperative complications determine short-term outcomes in patients with insulinoma: results of a bi-institutional study.

    abstract：BACKGROUND:Despite advancements in radiologic imaging and minimally invasive surgery, the evaluation and management of insulinomas is institution and surgeon dependent. Therefore, the reported surgical outcomes are highly variable. We compared the surgical management and outcomes of insulinomas between two internationa...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,多中心研究

    doi：10.1245/s10434-008-0157-y

    authors： Roland CL,Lo CY,Miller BS,Holt S,Nwariaku FE

    更新日期：2008-12-01 00:00:00

  • Identification of microRNA Biomarkers of Response to Neoadjuvant Chemoradiotherapy in Esophageal Adenocarcinoma Using Next Generation Sequencing.

    abstract：BACKGROUND:Clinical trials report improved overall survival following neoadjuvant chemoradiotherapy in patients undergoing surgery for esophageal adenocarcinoma, with a 10-15% survival improvement. MicroRNAs (miRNAs) are small noncoding RNAs that are known to direct the behavior of cancers, including response to treatm...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-018-6626-z

    authors： Chiam K,Mayne GC,Watson DI,Woodman RJ,Bright TF,Michael MZ,Karapetis CS,Irvine T,Phillips WA,Hummel R,Wang T,Pimlott LK,Marri S,Astill DS,Ruszkiewicz AR,Thompson SK,Hussey DJ

    更新日期：2018-09-01 00:00:00