Identification of microRNA Biomarkers of Response to Neoadjuvant Chemoradiotherapy in Esophageal Adenocarcinoma Using Next Generation Sequencing.

abstract：BACKGROUND:Lymph node (LN) status is one of the strongest prognostic factors after gallbladder cancer (GBC) resection. The adequate extension of LN dissection and the stratification of the prognosis in N+ patients have been debated. The present study aims to clarify these issues. METHODS:A total of 112 consecutive pat...

journal_title：Annals of surgical oncology

authors： Birnbaum DJ,Viganò L,Russolillo N,Langella S,Ferrero A,Capussotti L

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Pancreatic adenocarcinoma is among the most resistant of human cancers, yet specific mechanisms of treatment resistance remain poorly understood. Models to study pancreatic cancer resistance remain limited and should reflect in vivo changes that occur within patient tumors. We sought to identify consistent, ...

journal_title：Annals of surgical oncology

authors： Kim MP,Truty MJ,Choi W,Kang Y,Chopin-Lally X,Gallick GE,Wang H,McConkey DJ,Hwang R,Logsdon C,Abbruzzesse J,Fleming JB

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Intraoperative analysis of sentinel lymph nodes would enhance the care of early-stage oral squamous cell carcinoma (OSCC). We determined the frequency and extent of cytokeratin 19 (CK19) expression in OSCC primary tumours and surrounding tissues to explore the feasibility of a "clinic-ready" intraoperative d...

journal_title：Annals of surgical oncology

authors： Shaw R,Christensen A,Java K,Maddani RE,Liloglou T,Asterios T,von Buchwald C,Wessel I,Kiss K,Kjaer A,Lelkaitis G,Long A,Risk J,Robinson M

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Although perineural invasion (PNI) has been a poor prognostic factor for head and neck cancers, few studies have focused on oral squamous cell carcinoma (OSCC). The independent significance of PNI in early T1-2 OSCC and the benefit of treatment modification based on PNI status have not been assessed. This st...

journal_title：Annals of surgical oncology

authors： Tai SK,Li WY,Yang MH,Chang SY,Chu PY,Tsai TL,Wang YF,Chang PM

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:Reasons for variable utilization of adjuvant chemotherapy (ACT) for colon cancer have not been well described. We report medical oncology (MO) referral patterns and subsequent use of ACT. METHODS:Treatment records were linked to the population-based Ontario Cancer Registry to describe MO referral and ACT use a...

journal_title：Annals of surgical oncology

authors： Chandhoke G,Wei X,Nanji S,Biagi J,Peng Y,Krzyzanowska M,Mackillop WJ,Booth CM

更新日期：2016-08-01 00:00:00

abstract：:Gastrointestinal stromal tumors (GIST) are rare tumors of the gastrointestinal (GI) tract that arise from primitive mesenchymal cells. GISTs occur throughout the GI tract but are usually located in the stomach and small intestine. The majority of GISTs are immunohistochemically positive for c-kit protein (CD 117) and ...

journal_title：Annals of surgical oncology

authors： Pidhorecky I,Cheney RT,Kraybill WG,Gibbs JF

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:In breast cancer treatment, intraoperative sentinel lymph node (SLN) evaluation is used to identify patients who may potentially benefit from immediate completion of axillary lymph node dissection. METHODS:Prospectively collected breast cancer registry data identified 516 SLN biopsies between January 2003 a...

journal_title：Annals of surgical oncology

authors： Pugliese MS,Tickman R,Wang NP,Atwood M,Beatty JD

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Appendiceal goblet cell adenocarcinoma (GCA) is often misclassified and mistreated due to mixed histologic features. In general, cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) is standard of care for peritoneal carcinomatosis (PC) from mucinous appendiceal tumors; however, i...

journal_title：Annals of surgical oncology

authors： Zambrano-Vera K,Sardi A,Munoz-Zuluaga C,Studeman K,Nieroda C,Sittig M,King MC,Sipok A,Gushchin V

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Inflammatory breast cancer (IBC) is an aggressive disease that is treated with trimodality therapy consisting of neoadjuvant chemotherapy, surgery, and post-mastectomy radiation therapy (PMRT). Traditionally, modified radical mastectomy without reconstruction has been the operation of choice for patients wit...

journal_title：Annals of surgical oncology

authors： Simpson AB,McCray D,Wengler C,Crowe JP,Djohan R,Tendulkar R,O'Rourke C,Grobmyer SR,Valente SA

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Limited data are available on the use of cytoreductive surgery with hyperthermic intraperitoneal chemoperfusion (HIPEC) in patients with recurrent stage III ovarian cancer. METHODS:Patients with recurrent, heavily pretreated ovarian cancer were enrolled onto a phase II multimodal protocol consisting of exte...

journal_title：Annals of surgical oncology

authors： Ceelen WP,Van Nieuwenhove Y,Van Belle S,Denys H,Pattyn P

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:We sought to identify genes associated with the progression and metastasis of esophageal squamous-cell cancer by comparing the expression profiles of normal, primary cancer, and metastatic cancer cells isolated with laser microdissection. METHODS:Oligo microarray analysis identified several lymph node-speci...

journal_title：Annals of surgical oncology

authors： Kita Y,Mimori K,Iwatsuki M,Yokobori T,Ieta K,Tanaka F,Ishii H,Okumura H,Natsugoe S,Mori M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Debate regarding axillary dissection in the treatment of women with small invasive cancers of the breast has been increasing. Recently, omission of axillary dissection has been proposed because of the reported low incidence of nodal metastases in women with such cancers. Variation in the incidence of nodal m...

journal_title：Annals of surgical oncology

authors： Mustafa IA,Bland KI

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:This study investigated the effects of preoperative chemoradiotherapy (PCRT) and the prognoses of patients with mucinous rectal cancer compared with those with nonmucinous cancer. METHODS:We retrospectively reviewed the medical records of 368 patients who underwent curative resection after PCRT, between 200...

journal_title：Annals of surgical oncology

authors： Shin US,Yu CS,Kim JH,Kim TW,Lim SB,Yoon SN,Yoon YS,Kim CW,Kim JC

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Perturbations in the nuclear microenvironment, including transport systems, play a critical role in malignant progression, but the nuclear import abnormalities remain unclear in hepatocarcinogenesis. We analyzed the role of importin in hepatocellular carcinoma (HCC). METHODS:Gene expression profiling of the...

journal_title：Annals of surgical oncology

authors： Yoshitake K,Tanaka S,Mogushi K,Aihara A,Murakata A,Matsumura S,Mitsunori Y,Yasen M,Ban D,Noguchi N,Irie T,Kudo A,Nakamura N,Tanaka H,Arii S

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Ultrasonography and fine-needle aspiration (FNA) are used to evaluate the breast and regional nodes in breast cancer patients. We sought to identify factors influencing the sensitivity of ultrasonography for detection of nodal metastasis. METHODS:Patients with a clinically negative axilla who underwent axil...

journal_title：Annals of surgical oncology

authors： Bedrosian I,Bedi D,Kuerer HM,Fornage BD,Harker L,Ross MI,Ames FC,Krishnamurthy S,Edeiken-Monroe BS,Meric F,Feig BW,Akins J,Singletary SE,Mirza NQ,Hunt KK

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Extension of lymphadenectomy in gastric cancer is controversial, and preoperative diagnosis of lymph node metastases (LNM) is difficult. Therefore, knowledge-based systems such as the Maruyama computer program (MCP) are being developed. MCP shows good prognostic value for the compartments; however, for diffe...

journal_title：Annals of surgical oncology

authors： Bollschweiler EH,Mönig SP,Hensler K,Baldus SE,Maruyama K,Hölscher AH

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Despite a growing body of literature on oncologic and reconstructive outcomes after total skin-sparing mastectomy (TSSM), some questions related to this approach remain unanswered, including strategies for managing tumor involvement of the nipple while maintaining the aesthetic benefits of TSSM. METHODS:A p...

journal_title：Annals of surgical oncology

authors： Amara D,Peled AW,Wang F,Ewing CA,Alvarado M,Esserman LJ

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Sarcopenia, characterized by loss of skeletal muscle mass, is recognized as a prognostic factor in patients with gastric cancer. However, wide variability exists in the cutoff values of muscle mass for defining sarcopenia across previous studies, and the best cutoff values to predict survival remain unknown....

journal_title：Annals of surgical oncology

authors： Nishigori T,Tsunoda S,Obama K,Hisamori S,Hashimoto K,Itatani Y,Okada K,Sakai Y

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Here, we explored the genetic interactions between diabetes and oncogenic single-nucleotide polymorphisms (SNPs) that determine colorectal cancer (CRC) morbidity. METHODS:8q24 rs6983267 polymorphism analysis and cDNA microarray were performed in 107 CRCs to identify the genes associated with diabetes and th...

journal_title：Annals of surgical oncology

authors： Sugimachi K,Yamaguchi R,Eguchi H,Ueda M,Niida A,Sakimura S,Hirata H,Uchi R,Shinden Y,Iguchi T,Morita K,Yamamoto K,Miyano S,Mori M,Maehara Y,Mimori K

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Calciphylaxis is a rare condition associated with chronic renal failure and entails a very poor prognosis. Pathogenesis is poorly understood but involves abnormalities in calcium and phosphorus metabolism that lead to vascular and extravascular calcification. Patients present with painful ulcerating plaques ...

journal_title：Annals of surgical oncology

authors： Duffy A,Schurr M,Warner T,Chen H

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Symptomatic malignant ascites is a problem for patients with advanced intra-abdominal malignancy. Although the goal of paracentesis, the most common therapeutic intervention, is symptom palliation, the best method of assessing symptom improvement is unknown. The aim of this study was to assess the ability of...

journal_title：Annals of surgical oncology

authors： Easson AM,Bezjak A,Ross S,Wright JG

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Currently, cytoreductive surgery and hyperthermic intraperitoneal chemotherapy are accepted treatments for surgically resectable appendiceal epithelial neoplasms. However, for nonsurgical candidates, systemic treatment may be considered. The purpose of this analysis was to determine the benefit of biologic t...

journal_title：Annals of surgical oncology

authors： Choe JH,Overman MJ,Fournier KF,Royal RE,Ohinata A,Rafeeq S,Beaty K,Phillips JK,Wolff RA,Mansfield PF,Eng C

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Achieving an undetectable serum thyroglobulin (Tg) level (<1.0 ng/mL) after surgical and radioiodine treatment for papillary thyroid cancer (PTC) is associated with low recurrence rates and has been termed biochemical remission. This study aimed to determine the effectiveness of total thyroidectomy with ther...

journal_title：Annals of surgical oncology

authors： Hughes DT,Miller BS,Cohen MS,Doherty GM,Gauger PG

更新日期：2014-05-01 00:00:00

abstract：INTRODUCTION:Actual 5-year survival rates of 10-18% have been reported for patients with resected pancreatic adenocarcinoma (PC), but the use of multimodality therapy was uncommon in these series. We evaluated long-term survival and patterns of recurrence in patients treated for PC with contemporary staging and multimo...

journal_title：Annals of surgical oncology

authors： Katz MH,Wang H,Fleming JB,Sun CC,Hwang RF,Wolff RA,Varadhachary G,Abbruzzese JL,Crane CH,Krishnan S,Vauthey JN,Abdalla EK,Lee JE,Pisters PW,Evans DB

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Cancer antigen (CA) 125 tumor-associated antigen is a high molecular glycoprotein used for follow-up of epithelial ovarian cancer. The test is often requested as a differential diagnosis in patients with pleural or peritoneal fluid. This study analyzes the prevalence of CA-125 increases in a population of pa...

journal_title：Annals of surgical oncology

authors： Miralles C,Orea M,España P,Provencio M,Sánchez A,Cantos B,Cubedo R,Carcereny E,Bonilla F,Gea T

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Sentinel lymph node biopsy (SLNB) is associated with reduced morbidity, although lymphedema remains a significant complication. Previously, we found no association between number of excised lymph nodes (LNs) and measured lymphedema in SLNB patients. In this analysis, we examined the relationship between numb...

journal_title：Annals of surgical oncology

authors： Goldberg JI,Riedel ER,Morrow M,Van Zee KJ

更新日期：2011-10-01 00:00:00

abstract：:Adoptive cell transfer (ACT) of tumor-infiltrating lymphocytes (TILs) is an emerging immunotherapy for metastatic cancer. Surgeons play a central role in ACT treatments by performing resection of tumors from which TILs are isolated. It is important that surgeons have familiarity with this emerging treatment method bec...

journal_title：Annals of surgical oncology

authors： Crompton JG,Klemen N,Kammula US

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:The effectiveness of perioperative adjuvant chemotherapy for colorectal cancer liver metastasis (CRLM) remains a matter of debate. Despite the lack of clear evidence supporting its effectiveness after curative hepatectomy, adjuvant chemotherapy has been widely used clinically. The purpose of this study was t...

journal_title：Annals of surgical oncology

authors： Hirokawa F,Hayashi M,Miyamoto Y,Asakuma M,Shimizu T,Komeda K,Inoue Y,Uchiyama K

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The ACOSOG Z0011 (Z11) trial demonstrated that in patients with nonpalpable axillary lymph nodes (LN) and one to two positive sentinel LN (SLN), axillary LN dissection (ALND) is unnecessary.JAMA 305:569-575, [2011], Ann Surg 264:413-42, [2016] The Z11 trial did not require preoperative axillary ultrasound (a...

journal_title：Annals of surgical oncology

authors： Harris CK,Tran HT,Lee K,Mylander C,Pack D,Rosman M,Tafra L,Umbricht CB,Andrade R,Liang W,Jackson RS

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:The impact of postoperative complications on the administration of adjuvant therapy following pancreaticoduodenectomy (PD) for adenocarcinoma is still unclear. METHODS:A retrospective review of all patients undergoing PD at our institution between 1995 and 2011 was performed. Clinicopathological data, inclu...

journal_title：Annals of surgical oncology

authors： Wu W,He J,Cameron JL,Makary M,Soares K,Ahuja N,Rezaee N,Herman J,Zheng L,Laheru D,Choti MA,Hruban RH,Pawlik TM,Wolfgang CL,Weiss MJ

更新日期：2014-09-01 00:00:00