Metastasectomy for Tumor-Infiltrating Lymphocytes: An Emerging Operative Indication in Surgical Oncology.

abstract：BACKGROUND:Liver-directed therapies have been used to treat neuroendocrine liver metastases (NELM) for both symptomatic improvement and tumor growth control. We reviewed our experience with NELM to investigate the outcomes of available treatment modalities and to identify prognostic factors for survival. METHODS:We id...

journal_title：Annals of surgical oncology

authors： Fairweather M,Swanson R,Wang J,Brais LK,Dutton T,Kulke MH,Clancy TE

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Findings show that 5-10 % of women with a diagnosis of breast cancer (BCa) have actionable genetic mutations. The National Comprehensive Cancer Network guidelines for testing to detect BRCA1/2 mutations include personal history (PH) variables such as age of 45 years or younger and a family history (FH) varia...

journal_title：Annals of surgical oncology

authors： Kishan AU,Gomez CL,Dawson NA,Dvorak R,Foster NM,Hoyt A,Hurvitz SA,Kusske A,Silver EL,Tseng C,McCloskey SA

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Lymph node metastasis is widely accepted as one of the most important determinants of prognosis in colorectal cancer (CRC) patients. Therefore, there is an urgent need to identify molecular markers that can be used to predict lymph node metastasis. MATERIALS AND METHODS:Candidate genes were found using LMD ...

journal_title：Annals of surgical oncology

authors： Ozawa H,Iwatsuki M,Mimori K,Sato T,Johansson F,Toh H,Watanabe M,Mori M

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Surgical resection is the most important therapeutic intervention for eligible patients with pancreatic cancer; however, a majority of patients never receive surgery for a variety of reasons, including patient refusal. Utilizing the National Cancer Database, we investigated the associated sociodemographic an...

journal_title：Annals of surgical oncology

authors： Coffman A,Torgeson A,Lloyd S

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Identification of novel molecules implicated in the malignancy of gastric cancer (GC) is key to the development of personalized treatments and the improvement of patient outcome. Neurotrophin receptor-interacting melanoma antigen-encoding protein (NRAGE) regulates apoptosis and metastasis via interactions wi...

journal_title：Annals of surgical oncology

authors： Kanda M,Shimizu D,Fujii T,Tanaka H,Tanaka Y,Ezaka K,Shibata M,Takami H,Hashimoto R,Sueoka S,Iwata N,Kobayashi D,Tanaka C,Yamada S,Nakayama G,Sugimoto H,Koike M,Fujiwara M,Kodera Y

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Breast conservation therapy (BCT) and adjuvant hormonal therapy for estrogen-receptor positive breast cancers have become standard of care. Our objectives were to evaluate trends in the surgical management and adjuvant therapy for early-stage breast cancer and to identify factors predicting survival. METHOD...

journal_title：Annals of surgical oncology

authors： Kennedy T,Stewart AK,Bilimoria KY,Patel-Parekh L,Sener SF,Winchester DP

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:The Oncotype DX® assay has been validated in predicting response to adjuvant chemotherapy in breast cancer. Its role in neoadjuvant chemotherapy (NCT) has not been established. METHODS:The National Cancer Database was used to identify all patients with T1-T3, ER-positive, HER2-negative primary invasive brea...

journal_title：Annals of surgical oncology

authors： Pease AM,Riba LA,Gruner RA,Tung NM,James TA

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Microinvasive ductal carcinoma (DCISM), defined as DCIS with a focus of invasive carcinoma ≤ 1 mm, can be managed similarly to pure DCIS; however, management of the axilla in DCISM has been a subject of debate. Reports in the literature differ on the utility and necessity of sentinel lymph node biopsy (SLNB)...

journal_title：Annals of surgical oncology

authors： Fan B,Pardo JA,Serres S,Alapati AC,Szewczyk J,Mele A,James TA

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Oral squamous cell carcinoma (OSCC) is prevalent worldwide, and survival in OSCC has not improved significantly in the last few decades. MicroRNAs have an important regulatory role in oral carcinogenesis. This study investigated the prognostic implications of miR-196 expression and the rs11614913 genotype of...

journal_title：Annals of surgical oncology

authors： Liu CJ,Tsai MM,Tu HF,Lui MT,Cheng HW,Lin SC

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Intraoperative analysis of sentinel lymph nodes would enhance the care of early-stage oral squamous cell carcinoma (OSCC). We determined the frequency and extent of cytokeratin 19 (CK19) expression in OSCC primary tumours and surrounding tissues to explore the feasibility of a "clinic-ready" intraoperative d...

journal_title：Annals of surgical oncology

authors： Shaw R,Christensen A,Java K,Maddani RE,Liloglou T,Asterios T,von Buchwald C,Wessel I,Kiss K,Kjaer A,Lelkaitis G,Long A,Risk J,Robinson M

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:A significant proportion of women who have breast-conserving surgery (BCS) subsequently undergo re-excision or proceed to mastectomy. This study aimed to identify factors associated with residual disease after repeat surgery and to determine their effect on ipsilateral breast tumor recurrence (IBTR) and surv...

journal_title：Annals of surgical oncology

authors： Bodilsen A,Bjerre K,Offersen BV,Vahl P,Ejlertsen B,Overgaard J,Christiansen P

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The American Society of Clinical Oncology (ASCO) guidelines include incorporation of fertility preservation guidelines in the care of breast oncology patients. This study aimed to examine the baseline knowledge and preferences concerning fertility preservation among women of childbearing age with newly diagn...

journal_title：Annals of surgical oncology

authors： Goldfarb SB,Kamer SA,Oppong BA,Eaton A,Patil S,Junqueira MJ,Olcese C,Kelvin JF,Gemignani ML

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:The benefit of completion lymph node dissection (CLND) in melanoma patients with a positive sentinel lymph node (SLN) remains unknown. METHODS:We identified patients with a positive SLN from 1994 to 2012. Patient and tumor characteristics, reasons for not undergoing CLND, patterns of recurrence, and melanom...

journal_title：Annals of surgical oncology

authors： Bamboat ZM,Konstantinidis IT,Kuk D,Ariyan CE,Brady MS,Coit DG

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:The impact of cardiorespiratory comorbidity on operative outcomes after esophagectomy remains controversial. This study investigated the effect of cardiorespiratory comorbidity on postoperative complications for patients treated for esophageal or gastroesophageal junction cancer. PATIENTS AND METHODS:A Euro...

journal_title：Annals of surgical oncology

authors： Klevebro F,Elliott JA,Slaman A,Vermeulen BD,Kamiya S,Rosman C,Gisbertz SS,Boshier PR,Reynolds JV,Rouvelas I,Hanna GB,van Berge Henegouwen MI,Markar SR

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:There is considerable interest in a neoadjuvant approach for resectable pancreatic ductal adenocarcinoma (PDAC). This study evaluated perioperative gemcitabine + erlotinib (G+E) for resectable PDAC. METHODS:A multicenter, cooperative group, single-arm, phase II trial was conducted between April 2009 and Nov...

journal_title：Annals of surgical oncology

authors： Wei AC,Ou FS,Shi Q,Carrero X,O'Reilly EM,Meyerhardt J,Wolff RA,Kindler HL,Evans DB,Deshpande V,Misdraji J,Tamm E,Sahani D,Moore M,Newman E,Merchant N,Berlin J,Goff LW,Pisters P,Posner MC

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:This study assessed whether primary tumor maximum standardized uptake value (pSUVmax) measured by 18F-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) could improve the prediction of axillary lymph node (ALN) metastasis in invasive ductal breast cancer (IDC). METH...

journal_title：Annals of surgical oncology

authors： Song BI,Kim HW,Won KS

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Low-dose rate brachytherapy is a well-established adjuvant treatment for soft tissue sarcomas (STS). The experience with high-dose rate brachytherapy (HDR BT) in this indication is limited. The purpose of our study was to evaluate the viability of perioperative hyperfractionated HDR BT for STS. METHODS:Fort...

journal_title：Annals of surgical oncology

authors： Petera J,Soumarová R,Růzicková J,Neumanová R,Dusek L,Sirák I,Macingová Z,Paluska P,Kasaová L,Hodek M,Vosmik M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:In patients with early stage gastric cancer in the middle third of the stomach, pylorus-preserving gastrectomy (PPG) can be an option as function-preserving surgery, although its oncologic safety is not definitively defined. This issues may be overcome using the sentinel node (SN) concept. The aim of this st...

journal_title：Annals of surgical oncology

authors： Shimada A,Takeuchi H,Ono T,Kamiya S,Fukuda K,Nakamura R,Takahashi T,Wada N,Kawakubo H,Saikawa Y,Omori T,Nakahara T,Jinzaki M,Murakami K,Kitagawa Y

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Identification of the sentinel node (SN) in patients with breast cancer is done by tracking a radioactive tracer, a vital dye, or both, as the marker(s) reach the axilla. Replacing this method with ultrasonographic (US) recognition of the SN could eventually spare patients the need for systemic anesthesia, p...

journal_title：Annals of surgical oncology

authors： Kusminsky RE,Witsberger T,Todd Kuenstner J,Willis Trammell S,Schlarb CA,Maxwell D,Richmond BK,Boland JP

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Local excision might represent an alternative to total mesorectal excision for patients with locally advanced rectal cancer who achieve a major or complete clinical response after neoadjuvant chemoradiotherapy. METHODS:Between August 2005 and July 2011, 63 patients with mid-low rectal adenocarcinoma who had...

journal_title：Annals of surgical oncology

authors： D'Alimonte L,Bao QR,Spolverato G,Capelli G,Del Bianco P,Albertoni L,De Paoli A,Guerrieri M,Mantello G,Gambacorta MA,Canzonieri V,Valentini V,Coco C,Pucciarelli S

更新日期：2020-10-30 00:00:00

abstract：BACKGROUND:The involvement of lipids in carcinogenic and developmental processes has been reported in some malignancies, but their roles in gastric cancer remain to be analyzed. In this study, we compared the lipid content of gastric cancer tissue and adjacent nonneoplastic mucosa using imaging mass spectrometry. METH...

journal_title：Annals of surgical oncology

authors： Uehara T,Kikuchi H,Miyazaki S,Iino I,Setoguchi T,Hiramatsu Y,Ohta M,Kamiya K,Morita Y,Tanaka H,Baba S,Hayasaka T,Setou M,Konno H

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Many invasive breast cancers are accompanied by a variety of noninvasive components. Histological distinctions have been made between these components, but to understand their importance, it is essential to examine their molecular biology. METHODS:Proliferative indices, oncoproteins, and steroid receptor ex...

journal_title：Annals of surgical oncology

authors： Brower ST,Ahmed S,Tartter PI,Bleiweiss I,Amberson JB

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Contralateral prophylactic mastectomy (CPM) is expected to add surgical morbidity but this incremental risk has not yet been defined. We sought to quantify the additional risks associated with CPM and determine how these risks influence the time to adjuvant therapy. METHODS:We identified women undergoing ma...

journal_title：Annals of surgical oncology

authors： Eck DL,Perdikis G,Rawal B,Bagaria S,McLaughlin SA

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Adjuvant chemoradiotherapy improved survival in patients with resected gastric adenocarcinoma in the Southwest Oncology Group/Intergroup 0116 trial. Our objective was to examine the impact of adjuvant treatment on overall survival (OS) in the general population. METHODS:Patients 18-85 years old who had unde...

journal_title：Annals of surgical oncology

authors： Coburn NG,Govindarajan A,Law CH,Guller U,Kiss A,Ringash J,Swallow CJ,Baxter NN

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Carcinomatosis of colorectal origin is increasingly treated by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CS-HIPEC). This procedure commonly involves multivisceral resection (MVR) with potentially high morbidity. We analyzed the effect of MVR on the outcome after CS-HIPEC. METHODS:...

journal_title：Annals of surgical oncology

authors： Franko J,Gusani NJ,Holtzman MP,Ahrendt SA,Jones HL,Zeh HJ 3rd,Bartlett DL

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Esophageal cancer is an aggressive cancer with poor prognosis. However, little is known about the immune response in the tumor microenvironment after neoadjuvant chemotherapy. PURPOSE:To investigate the immunological impact of neoadjuvant chemotherapy in the tumor microenvironment of esophageal squamous cel...

journal_title：Annals of surgical oncology

authors： Tsuchikawa T,Miyamoto M,Yamamura Y,Shichinohe T,Hirano S,Kondo S

更新日期：2012-05-01 00:00:00

abstract：: ...

journal_title：Annals of surgical oncology

authors： Poorman CE,Ethun CG,Maithel SK

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The goal of this study was to determine the oncologic outcomes in localized resectable soft-tissue sarcoma after pre- versus postoperative radiation. METHODS:Literature searches through MEDLINE, EMBASE, CancerLit, and the Cochrane Database were performed with the following search terms: sarcoma, radiation, ...

journal_title：Annals of surgical oncology

authors： Al-Absi E,Farrokhyar F,Sharma R,Whelan K,Corbett T,Patel M,Ghert M

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:0.6-12.7% of patients with primary cutaneous melanoma will develop additional melanomas. Pathologic features of tumors in patients with multiple primary cutaneous melanomas have not been well described. In this large, international, multicenter, case-control study, we compared the clinicopathologic features ...

journal_title：Annals of surgical oncology

authors： Murali R,Goumas C,Kricker A,From L,Busam KJ,Begg CB,Dwyer T,Gruber SB,Kanetsky PA,Orlow I,Rosso S,Thomas NE,Berwick M,Scolyer RA,Armstrong BK,GEM Study Group.

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The efficacy, toxicity, and patterns of failure of esophageal squamous cell carcinoma (ESCC) treated with selective lymph node (SLN) conventional fraction radiotherapy (CFRT) and S-1 plus cisplatin (CDDP) were evaluated. PATIENTS AND METHODS:67 Patients with clinical stage II-IVa ESCC were enrolled. The tot...

journal_title：Annals of surgical oncology

authors： Wang X,Liu X,Li D,Wang X,Huang W,Li B

更新日期：2019-06-01 00:00:00