The immunological impact of neoadjuvant chemotherapy on the tumor microenvironment of esophageal squamous cell carcinoma.

abstract：PURPOSE:Reasons for variable utilization of adjuvant chemotherapy (ACT) for colon cancer have not been well described. We report medical oncology (MO) referral patterns and subsequent use of ACT. METHODS:Treatment records were linked to the population-based Ontario Cancer Registry to describe MO referral and ACT use a...

journal_title：Annals of surgical oncology

authors： Chandhoke G,Wei X,Nanji S,Biagi J,Peng Y,Krzyzanowska M,Mackillop WJ,Booth CM

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Examination of pathology slides is a routine part of a breast cancer second opinion. The purpose of this study was to determine how often the pathologic second opinion (1) altered the diagnosis and (2) resulted in a change in the surgical procedure. METHODS:Patients presenting between 1997 and 2001 for a se...

journal_title：Annals of surgical oncology

authors： Staradub VL,Messenger KA,Hao N,Wiley EL,Morrow M

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Inconsistent data suggests extranodal spread (ENS) is an adverse prognostic factor in Stage III melanoma patients but it remains contentious. By rigorously matching cohorts, this study sought to clarify associations with recurrence and survival. METHODS:Melanoma patients with lymph node metastases (AJCC Sta...

journal_title：Annals of surgical oncology

authors： Crookes TR,Scolyer RA,Lo S,Drummond M,Spillane AJ

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Current mammographic technology has resulted in increased detection of ductal carcinoma in situ (DCIS). It is necessary to assess which patients presenting with DCIS are good candidates for breast conservation and which of these patients should receive adjuvant radiation. METHODS:We accrued clinical data fo...

journal_title：Annals of surgical oncology

authors： Fish EB,Chapman JA,Miller NA,Link MA,Fishell E,Wright B,McCready DR,Hiraki GY,Ross TM,Hanna WM,Lickley HL

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Peritoneal carcinomatosis of colorectal cancer is probably best treated by cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC). In The Netherlands Cancer Institute, this treatment has been performed since 1995. The long tradition of this treatment enabled us to study long-term survival in det...

journal_title：Annals of surgical oncology

authors： Verwaal VJ,van Ruth S,Witkamp A,Boot H,van Slooten G,Zoetmulder FA

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Robotic total mesorectal excision (R-TME), a novel way for minimally invasive treatment of rectal cancer, was shown in previous studies to be safe and effective. However, comparison with laparoscopic total mesorectal excision (L-TME) has drawn contradictory disputes, especially concerning operative high-risk...

journal_title：Annals of surgical oncology

authors： Colombo PE,Bertrand MM,Alline M,Boulay E,Mourregot A,Carrère S,Quénet F,Jarlier M,Rouanet P

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the feasibility and safety in terms of prognostic significance and perioperative morbidity and mortality of cytoreduction in patients affected by advance ovarian cancer and hepato-biliary metastasis. METHODS:Patients with a least one hepatobiliary metastasis who have...

journal_title：Annals of surgical oncology

authors： Di Donato V,Giannini A,D'Oria O,Schiavi MC,Di Pinto A,Fischetti M,Lecce F,Perniola G,Battaglia F,Berloco P,Muzii L,Benedetti Panici P

更新日期：2021-01-01 00:00:00

abstract：AIM:We evaluated preoperative serum carcinoembryonic antigen (CEA) as a prognostic factor for colorectal cancer and determined when surveillance of this marker was useful. METHODS:Serum CEA was measured preoperatively in 1,263 patients who underwent curative resection for colorectal cancer at 3-month intervals for the...

journal_title：Annals of surgical oncology

authors： Park IJ,Choi GS,Lim KH,Kang BM,Jun SH

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:CD44, a cancer stem cell surface marker, is associated with treatment resistance and prognosis in some cancers. In the present study, we examined the predictive value of CD44 in muscle-invasive bladder cancer (MIBC). METHODS:We retrospectively analyzed the clinical outcomes of 105 MIBC patients and correlat...

journal_title：Annals of surgical oncology

authors： Wu CT,Lin WY,Chen WC,Chen MF

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Radical gastrectomy is the cornerstone of the treatment of locally advanced gastric cancer. This study was designed to evaluate factors associated with a tumor-positive resection margin after gastrectomy and to evaluate the influence of hospital volume. METHODS:In this Dutch cohort study, patients with junc...

journal_title：Annals of surgical oncology

authors： van der Werf LR,Cords C,Arntz I,Belt EJT,Cherepanin IM,Coene PLO,van der Harst E,Heisterkamp J,Langenhoff BS,Lamme B,van Berge Henegouwen MI,Lagarde SM,Wijnhoven BPL

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Gastrointestinal leak (GIL) after cytoreductive surgery with heated intraperitoneal chemotherapy (CRS/HIPEC) is associated with significant morbidity and mortality. This study aimed to identify GIL prognostic factors and its impact on overall survival. METHODS:A retrospective analysis of a prospectively mai...

journal_title：Annals of surgical oncology

authors： Chouliaras K,Levine EA,Fino N,Shen P,Votanopoulos KI

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:CD44 isoforms serve as a marker for cancer stem cells. CD44 variant 9 (CD44v9) contributes to the defense against reactive oxygen species, resulting in resistance to chemoradiotherapy. However, the significance of CD44v9 in patients with lung adenocarcinoma is unknown. METHODS:We used immunohistochemical an...

journal_title：Annals of surgical oncology

authors： Akamine T,Tagawa T,Ijichi K,Toyokawa G,Takamori S,Hirai F,Okamoto T,Oda Y,Maehara Y

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:The performance of a mastectomy for the treatment or prophylaxis of breast cancer may have long-term implications for both physical and mental well-being in women. The development of breast numbness and phantom breast sensations following mastectomy is well-known; however, relatively little is known about phy...

journal_title：Annals of surgical oncology

authors： McCarthy CM,Mehrara BJ,Long T,Garcia P,Kropf N,Klassen AF,Cano SJ,Li Y,Hurley K,Scott A,Disa JJ,Cordeiro PG,Pusic AL

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:Chemoradiation (CT/RT) followed by radical surgery (RS) may play a role in locally advanced cervical cancer (LACC) patients with suboptimal response to CT/RT or in low-income countries with limited access to radiotherapy. Our aim is to evaluate oncological and surgical outcomes of minimally invasive radical sur...

journal_title：Annals of surgical oncology

authors： Ferrandina G,Gallotta V,Federico A,Fanfani F,Ercoli A,Chiantera V,Cosentino F,Turco LC,Legge F,Anchora LP,Bizzarri N,Moroni R,Macchia G,Valentini V,Scambia G

更新日期：2020-11-09 00:00:00

abstract：BACKGROUND:Guidelines regarding specific resection margins for primary Merkel cell carcinoma (MCC) are not well established. The current National Comprehensive Cancer Network (NCCN) guidelines recommend 1- to 2-cm resection margins. This study aimed to determine the impact of margin width on local recurrence (LR), dise...

journal_title：Annals of surgical oncology

authors： Perez MC,de Pinho FR,Holstein A,Oliver DE,Naqvi SMH,Kim Y,Messina JL,Burke E,Gonzalez RJ,Sarnaik AA,Cruse CW,Wuthrick EJ,Harrison LB,Sondak VK,Zager JS

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Melphalan (L-PAM) hyperthermic isolated limb perfusion (HILP) is currently considered the standard treatment for patients with in-transit metastases from cutaneous melanoma. We here report on the results of L-PAM and low-dose tumor necrosis factor (TNF)alpha HILP in patients with bulky disease. METHODS:Twen...

journal_title：Annals of surgical oncology

authors： Rossi CR,Foletto M,Mocellin S,Pilati P,Lise M

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Persistent/recurrent primary hyperparathyroidism (pHPT) occurs frequently in multiple endocrine neoplasia type 1 (MEN1). We assessed the usefulness of intraoperative PTH (IOPTH) and preoperative localizing studies based on the outcome of patients with MEN1-associated pHPT undergoing reoperative surgery. MET...

journal_title：Annals of surgical oncology

authors： Keutgen XM,Nilubol N,Agarwal S,Welch J,Cochran C,Marx SJ,Weinstein LS,Simonds WF,Kebebew E

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:The causes underlying the phenomenon of simultaneous medullary (MTC) and papillary thyroid cancer (PTC) are unclear. METHODS:This study of 26 patients with simultaneous MTC and PTC aimed at clarifying clinical and histopathologic characteristics and trends of this unusual condition among MTC and PTC patient...

journal_title：Annals of surgical oncology

authors： Machens A,Dralle H

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Data on isolated limb perfusion (ILP) in elderly melanoma patients are scarce. We aimed to evaluate the efficacy and safety of ILP in our institutional cohort of melanoma patients. METHODS:We performed retrospective analysis of stage IIIB/C melanoma patients who underwent ILP for melanoma in-transit metasta...

journal_title：Annals of surgical oncology

authors： Madu MF,Deken MM,van der Hage JA,Jóźwiak K,Wouters MWJM,van Akkooi ACJ

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:CA 19-9 levels are useful for the diagnosis of patients with pancreatic adenocarcinoma. However, interest has recently turned toward its use as a prognostic indicator. The purpose of this study is to determine whether postoperative CA 19-9 levels predict disease-free survival (DFS) and median survival (MS) i...

journal_title：Annals of surgical oncology

authors： Montgomery RC,Hoffman JP,Riley LB,Rogatko A,Ridge JA,Eisenberg BL

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:After introduction of the clamp-crushing technique in the 1970s, various devices have been developed for transection of the liver with the aim of further reducing blood loss and improving the outcome of patients who undergo hepatic resection. We performed a meta-analysis to quantitatively compare the clamp-c...

journal_title：Annals of surgical oncology

authors： Rahbari NN,Koch M,Schmidt T,Motschall E,Bruckner T,Weidmann K,Mehrabi A,Büchler MW,Weitz J

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Reactive oxygen species (free radicals) play an important role in carcinogenesis. Extensive antioxidant defense mechanisms counteract free radicals in mammalian cells. Oxidative stress is a disturbance in the balance between the production of free radicals and antioxidant defenses. There is direct evidence t...

journal_title：Annals of surgical oncology

authors： Kilic N,Yavuz Taslipinar M,Guney Y,Tekin E,Onuk E

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:In cutaneous melanoma (CM), the present methods of lymph node (LN) staging have not sufficiently utilized the prognostic information of metastatic LNs. In this study, we aimed to construct prognostic nomograms based on the number of positive LNs (PLNs) and other clinicopathologic characteristics of CM patien...

journal_title：Annals of surgical oncology

authors： Li W,Xu X,Zhang Y

更新日期：2021-01-11 00:00:00

abstract：BACKGROUND:L-phenylalanine mustard (LPAM) has been the standard for use in regional chemotherapy (RC) for unresectable in-transit melanoma. Preclinical data demonstrated that regional temozolomide (TMZ) may be more effective. METHODS:Patients with AJCC Stage IIIB or IIIC extremity melanoma who failed previous LPAM-bas...

journal_title：Annals of surgical oncology

authors： Beasley GM,Speicher P,Augustine CK,Dolber PC,Peterson BL,Sharma K,Mosca PJ,Royal R,Ross M,Zager JS,Tyler DS

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine the feasibility and optimal timing of quality of life assessment for patients undergoing palliative surgical evaluation. METHODS:Patients with an advanced malignancy undergoing consultation for palliative surgical intervention were prospectively enrolled from Novem...

journal_title：Annals of surgical oncology

authors： Badgwell B,Krouse R,Cormier J,Guevara C,Klimberg VS,Ferrell B

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The added value of surgery in breast cancer patients with pathological complete response (pCR) after neoadjuvant systemic therapy (NST) is uncertain. The accuracy of imaging identifying pCR for omission of surgery, however, is insufficient. We investigated the accuracy of ultrasound-guided biopsies identifyi...

journal_title：Annals of surgical oncology

authors： van Loevezijn AA,van der Noordaa MEM,van Werkhoven ED,Loo CE,Winter-Warnars GAO,Wiersma T,van de Vijver KK,Groen EJ,Blanken-Peeters CFJM,Zonneveld BJGL,Sonke GS,van Duijnhoven FH,Vrancken Peeters MTFD

更新日期：2020-12-02 00:00:00

abstract：BACKGROUND:The patients with early gastric cancer who have undergone incomplete endoscopic resection (ER) generally need additional surgery because of the possibility of lymph node metastasis. The aim of study was to evaluate the optimal time interval from ER to additive surgery by evaluating the effect of time interva...

journal_title：Annals of surgical oncology

authors： Kim MJ,Kim JH,Lee YC,Kim JW,Choi SH,Hyung WJ,Noh SH,Youn YH,Park H,Lee SI

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Axillary nodal status is the most important prognostic factor for patients with breast cancer. Clinical assessment and imaging modalities are not always reliable. Surgical removal and histopathological examination of axillary lymph nodes remain essential methods of staging the axilla. However, the optimal ma...

journal_title：Annals of surgical oncology

authors： Samphao S,Eremin JM,El-Sheemy M,Eremin O

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to investigate the diagnostic and prognostic value of circulating endothelial cell (CEC), a potential surrogate of tumor angiogenesis, in malignant pleural mesothelioma (MPM). METHODS:We prospectively evaluated CEC count in 4.0 mL of peripheral blood sampled from patients with ...

journal_title：Annals of surgical oncology

authors： Yoneda K,Tanaka F,Kondo N,Orui H,Hashimoto M,Takuwa T,Matsumoto S,Okumura Y,Tsubota N,Sato A,Tsujimura T,Kuribayashi K,Fukuoka K,Nakano T,Hasegawa S

更新日期：2012-12-01 00:00:00

abstract：PURPOSE:Intraoperative margin assessment can reduce positive margins in patients undergoing breast-conserving surgery. However, reports on intraoperative margin assessment have described only the use of either imprint cytology or frozen section. This study was designed to elucidate the effect of intraoperative margin a...

journal_title：Annals of surgical oncology

authors： Tamanuki T,Namura M,Aoyagi T,Shimizu S,Suwa T,Matsuzaki H

更新日期：2020-08-19 00:00:00