Management of Neuroendocrine Tumor Liver Metastases: Long-Term Outcomes and Prognostic Factors from a Large Prospective Database.

abstract：BACKGROUND:Several clinical risk scores for patients with colorectal liver metastases (CLM) were established in cohorts of patients undergoing liver resection (LR) without neoadjuvant chemotherapy (NAC). The purpose of the study was to evaluate the predictive values of four common risk scores in the setting of NAC and ...

journal_title：Annals of surgical oncology

authors： Wimmer K,Schwarz C,Szabo C,Bodingbauer M,Tamandl D,Mittlböck M,Kaczirek K

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:We provide a statistical analysis of the learning phase for sentinel node biopsy. METHODS:Four learning phases were analyzed: 25, 50, 75, and 150 procedures with a corresponding number of 10, 20, 30, and 60 tumor-positive cases. Critical values of nonidentification rate and false-negative rate were defined....

journal_title：Annals of surgical oncology

authors： Tanis PJ,Nieweg OE,Hart AA,Kroon BB

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Emerging evidence suggests that G9a, a histone methyltransferase, is involved in tumor progression and metastasis. However, the functional significance of G9a in endometrial carcinogenesis has not been defined. METHODS:The differential expression of G9a in cancer and normal tissues was assessed using an arr...

journal_title：Annals of surgical oncology

authors： Hsiao SM,Chen MW,Chen CA,Chien MH,Hua KT,Hsiao M,Kuo ML,Wei LH

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Pathologic complete response (pCR) of rectal cancer following neoadjuvant therapy is associated with decreased local recurrence and increased overall survival. This study utilizes a national dataset to identify predictors of pCR in patients with rectal cancer. METHODS:The National Cancer Database was querie...

journal_title：Annals of surgical oncology

authors： Lorimer PD,Motz BM,Kirks RC,Boselli DM,Walsh KK,Prabhu RS,Hill JS,Salo JC

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Identification of novel molecules implicated in the malignancy of gastric cancer (GC) is key to the development of personalized treatments and the improvement of patient outcome. Neurotrophin receptor-interacting melanoma antigen-encoding protein (NRAGE) regulates apoptosis and metastasis via interactions wi...

journal_title：Annals of surgical oncology

authors： Kanda M,Shimizu D,Fujii T,Tanaka H,Tanaka Y,Ezaka K,Shibata M,Takami H,Hashimoto R,Sueoka S,Iwata N,Kobayashi D,Tanaka C,Yamada S,Nakayama G,Sugimoto H,Koike M,Fujiwara M,Kodera Y

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:The aim of this study was to identify predictors of 30-day mortality in patients with malignant pleural effusion (MPE) who need pleural palliative procedures. METHODS:Data was prospectively collected from our database, between January 2013 and July 2014 on 86 patients with MPE and complete follow-up 30 days...

journal_title：Annals of surgical oncology

authors： Abrao FC,de Abreu IR,Fogarolli M,Caxeiro G,Bezerra CB,de Cerqueira Cesar FP,Rocha PS,Younes RN

更新日期：2015-11-01 00:00:00

abstract：PURPOSE:The purpose of this study was to obtain a comprehensive understanding of the impact of postoperative tumor marker (TM) normalization on survival after pancreatectomy for pancreatic carcinoma. We propose the concept of surgical RECIST based on residual tumor and TM status. METHODS:A total of consecutive patient...

journal_title：Annals of surgical oncology

authors： Motoi F,Rikiyama T,Katayose Y,Egawa S,Unno M

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Invasive ductal carcinoma (IDC) with lobular features (IDC-L) is not recognized as a subtype of breast cancer. We previously showed that IDC-L may be a variant of IDC with clinicopathological characteristics more similar to invasive lobular carcinoma (ILC). We sought to determine the re-excision rates of IDC...

journal_title：Annals of surgical oncology

authors： Arps DP,Jorns JM,Zhao L,Bensenhaver J,Kleer CG,Pang JC

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:For some types of cancer, postoperative complications can negatively influence survival, but the association between these complications and oncological outcomes is unclear for patients with esophageal cancer who receive preoperative treatments. METHODS:Data were retrospectively analyzed for patients who un...

journal_title：Annals of surgical oncology

authors： Yamashita K,Makino T,Miyata H,Miyazaki Y,Takahashi T,Kurokawa Y,Yamasaki M,Nakajima K,Takiguchi S,Mori M,Doki Y

更新日期：2016-06-01 00:00:00

abstract：:The Editors of Annals of Surgical Oncology have retracted the following poster session abstract following an investigation by the authors' institution, which found that the study was not submitted to the IRB for approval. ...

journal_title：Annals of surgical oncology

authors： Hayes M,Bloomquist E,Wright H

更新日期：2018-04-20 00:00:00

abstract：BACKGROUND:Cytotoxic T lymphocyte-associated antigen (CTLA)-4 can inhibit T-cell responses and is involved in tolerance against self antigens. We previously reported autoimmune manifestations and objective cancer regressions in patients with metastatic melanoma treated with CTLA-4 blockade. The possibility of activatin...

journal_title：Annals of surgical oncology

authors： Maker AV,Phan GQ,Attia P,Yang JC,Sherry RM,Topalian SL,Kammula US,Royal RE,Haworth LR,Levy C,Kleiner D,Mavroukakis SA,Yellin M,Rosenberg SA

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Biomarkers for accurate diagnosis of early hepatocellular carcinoma (HCC) are limited in number and clinical validation. We applied SELDI-TOF-MS ProteinChip technology to identify serum profile for distinguishing HCC and liver cirrhosis (LC) and to compare the accuracy of SELDI-TOF-MS profile and alpha-fetop...

journal_title：Annals of surgical oncology

authors： Chen L,Ho DW,Lee NP,Sun S,Lam B,Wong KF,Yi X,Lau GK,Ng EW,Poon TC,Lai PB,Cai Z,Peng J,Leng X,Poon RT,Luk JM

更新日期：2010-09-01 00:00:00

abstract：INTRODUCTION:The rate of contralateral prophylactic mastectomy (CPM) has recently increased. The aim of this study is to assess perceptions of contralateral breast cancer (CBC) risk among breast cancer patients and to evaluate tumor and patient factors associated with risk perception. METHODS:We conducted a prospectiv...

journal_title：Annals of surgical oncology

authors： Abbott A,Rueth N,Pappas-Varco S,Kuntz K,Kerr E,Tuttle T

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:We performed a phase I study of a novel system of complete hepatic venous isolation and extracorporeal chemofiltration in patients with unresectable hepatocellular carcinoma (HCC) to determine (a) whether systemic exposure to doxorubicin could be limited after high-dose hepatic arterial infusion (HAI), and (...

journal_title：Annals of surgical oncology

authors： Curley SA,Newman RA,Dougherty TB,Fuhrman GM,Stone DL,Mikolajek JA,Guercio S,Guercio A,Carrasco CH,Kuo MT

更新日期：1994-09-01 00:00:00

abstract：:In the original article Massimo Milione's last name was spelled incorrectly. It is correct as reflected here. The original article has also been updated. ...

journal_title：Annals of surgical oncology

authors： Guaglio M,Sinukumar S,Kusamura S,Milione M,Pietrantonio F,Battaglia L,Guadagni S,Baratti D,Deraco M

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:In a mouse model of hepatic metastasis, we herein analyzed whether the CXC chemokine macrophage inflammatory protein (MIP)-2, a functional analogue of the human interleukin 8, stimulates tumor cell migration in vitro and angiogenesis and tumor growth in vivo. METHODS:By using chemotaxis chambers, CT26.WT co...

journal_title：Annals of surgical oncology

authors： Kollmar O,Scheuer C,Menger MD,Schilling MK

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Most cytokine-based cancer gene therapy clinical trials have used labor-intensive, retrovirus-mediated strategies resulting in unpredictable gene expression. Recombinant AdV vectors were evaluated for easier, more reproducible gene transfer into 12 human melanoma, 2 murine fibrosarcomas, and 8 other tumor ce...

journal_title：Annals of surgical oncology

authors： Toloza EM,Hunt K,Miller AR,McBride W,Lau R,Swisher S,Rhoades K,Arthur J,Choi J,Chen L,Chang P,Chen A,Glaspy J,Economou JS

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Microsatellites are short repetitive nucleotide sequences that, through mutation, can undergo either expansion or contraction. This novel mutational mechanism known as microsatellite instability may play a role in carcinogenesis. We investigated the incidence of microsatellite instability in a series of prim...

journal_title：Annals of surgical oncology

authors： Rush EB,Calvano JE,van Zee KJ,Zelenetz AD,Borgen PI

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Sentinel lymph node biopsy (SLNB) has become standard of care as a staging procedure in patients with invasive breast cancer. A positive SLNB allows completion axillary lymph node dissection (cALND) to be performed. The axillary recurrence rate (ARR) after cALND in patients with positive SLNB is low. Recentl...

journal_title：Annals of surgical oncology

authors： Francissen CM,Dings PJ,van Dalen T,Strobbe LJ,van Laarhoven HW,de Wilt JH

更新日期：2012-12-01 00:00:00

abstract：PURPOSE:To determine survival differences for patients undergoing colonic or rectal resection for cancer on the basis of the specific anatomical location of primary tumor. METHODS:A total of 143,747 patients undergoing segmental colectomy, hemicolectomy, anterior resection, or abdominoperineal resection (APER) for ade...

journal_title：Annals of surgical oncology

authors： Bhangu A,Kiran RP,Slesser A,Fitzgerald JE,Brown G,Tekkis P

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:The appropriate management of breast cancer risk in BRCA mutation carriers following ovarian cancer diagnosis remains unclear. We sought to determine the survival benefit and cost effectiveness of risk-reducing mastectomy (RRM) among women with BRCA1/2 mutations following stage II-IV ovarian cancer. DESIGN:...

journal_title：Annals of surgical oncology

authors： Gamble C,Havrilesky LJ,Myers ER,Chino JP,Hollenbeck S,Plichta JK,Kelly Marcom P,Shelley Hwang E,Kauff ND,Greenup RA

更新日期：2017-10-01 00:00:00

abstract：PURPOSE:With the exception of papillary and follicular thyroid cancer, malignant cancers of the thyroid, parathyroid, adrenal, and endocrine pancreas are uncommon. These rare malignancies present a challenge to both the clinician and patient, because few data exist on their incidence or survival. We analyzed the incide...

journal_title：Annals of surgical oncology

authors： James BC,Aschebrook-Kilfoy B,Cipriani N,Kaplan EL,Angelos P,Grogan RH

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The role of surgical resection in patients with large or multinodular hepatocellular carcinoma (HCC) remains unclear. This study evaluated the long-term outcome of patients with hepatic resection for large (>5 cm in diameter) or multinodular (more than three nodules) HCC by using a multi-institutional databa...

journal_title：Annals of surgical oncology

authors： Ng KK,Vauthey JN,Pawlik TM,Lauwers GY,Regimbeau JM,Belghiti J,Ikai I,Yamaoka Y,Curley SA,Nagorney DM,Ng IO,Fan ST,Poon RT,International Cooperative Study Group on Hepatocellular Carcinoma.

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:The 5th edition of Breast Imaging Reporting and Data System subdivides suspicious calcifications into two categories: 4B-amorphous, coarse heterogeneous, and fine pleomorphic calcifications; 4C-fine linear or fine linear branching calcifications. We investigated whether these revised categories are appropria...

journal_title：Annals of surgical oncology

authors： Kim SY,Kim HY,Kim EK,Kim MJ,Moon HJ,Yoon JH

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:As increased focus is placed on quality of care in surgery, readmission is an increasingly important metric by which hospital and surgeon quality is measured. For complex pancreatic surgery, we hypothesized that increased pancreaticoduodenectomy (PD) volume may mitigate readmission rates. METHODS:The Univer...

journal_title：Annals of surgical oncology

authors： Sutton JM,Wilson GC,Wima K,Hoehn RS,Cutler Quillin R 3rd,Hanseman DJ,Paquette IM,Sussman JJ,Ahmad SA,Shah SA,Abbott DE

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Here, we explored the genetic interactions between diabetes and oncogenic single-nucleotide polymorphisms (SNPs) that determine colorectal cancer (CRC) morbidity. METHODS:8q24 rs6983267 polymorphism analysis and cDNA microarray were performed in 107 CRCs to identify the genes associated with diabetes and th...

journal_title：Annals of surgical oncology

authors： Sugimachi K,Yamaguchi R,Eguchi H,Ueda M,Niida A,Sakimura S,Hirata H,Uchi R,Shinden Y,Iguchi T,Morita K,Yamamoto K,Miyano S,Mori M,Maehara Y,Mimori K

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:The term pseudomyxoma peritonei has been used in reference to any condition, benign or malignant, in which the peritoneal cavity becomes filled with a gelatinous substance. The term is nonspecific and does not denote therapeutic or prognostic significance. Controversy centers around which patients benefit fr...

journal_title：Annals of surgical oncology

authors： Wirtzfeld DA,Rodriguez-Bigas M,Weber T,Petrelli NJ

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:The rarity of melanoma in young patients, particularly pediatric ones, has to date precluded any valid comparisons being made between young patients and adults undergoing sentinel lymph node biopsy (SLNB) for intermediate thickness localized melanoma. The present study takes advantage of the large Sydney Mel...

journal_title：Annals of surgical oncology

authors： Howman-Giles R,Shaw HM,Scolyer RA,Murali R,Wilmott J,McCarthy SW,Uren RF,Thompson JF

更新日期：2010-01-01 00:00:00

abstract：:Tumors treated with preoperative chemotherapy or radiation often demonstrate evidence of response in the resection specimen. Pathologic response is often interpreted as a surrogate for recurrence or survival outcomes. With a valid surrogate for long-term outcomes, investigators can explore treatment strategies with im...

journal_title：Annals of surgical oncology

authors： Mansour JC,Schwarz RE

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:The impact of postoperative complications on the administration of adjuvant therapy following pancreaticoduodenectomy (PD) for adenocarcinoma is still unclear. METHODS:A retrospective review of all patients undergoing PD at our institution between 1995 and 2011 was performed. Clinicopathological data, inclu...

journal_title：Annals of surgical oncology

authors： Wu W,He J,Cameron JL,Makary M,Soares K,Ahuja N,Rezaee N,Herman J,Zheng L,Laheru D,Choti MA,Hruban RH,Pawlik TM,Wolfgang CL,Weiss MJ

更新日期：2014-09-01 00:00:00