Pathologic response to preoperative therapy: does it mean what we think it means?

abstract：BACKGROUND:Surgery is the standard treatment for primary, gastrointestinal stromal tumor (GIST); however, surgical resection often is not curative, particularly in large GIST. Five years after complete removal of their tumor, approximately half of treated patients relapse. Imatinib, an oral tyrosine kinase inhibitor (T...

journal_title：Annals of surgical oncology

authors： Hohenberger P,Eisenberg B

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:The main goal of the current study was to compare survival differences among subgroups of primary ovarian cancer patients in International Federation of Gynecology and Obstetrics (FIGO) stages IIIC and IIIA1 after complete tumor debulking surgery. METHODS:A total of 218 patients with primary ovarian cancer w...

journal_title：Annals of surgical oncology

authors： Gasimli K,Braicu EI,Nassir M,Richter R,Babayeva A,Chekerov R,Darb-Esfahani S,Sehouli J,Muallem MZ

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Hepatic resection for colorectal liver metastasis (CLM) with concomitant extrahepatic disease (EHD) is a controversial topic. We sought to evaluate the long-term outcome of patients undergoing liver resection for CLM in presence of EHD and identify factors associated with prognosis. METHODS:From 1996 to 200...

journal_title：Annals of surgical oncology

authors： Pulitanò C,Bodingbauer M,Aldrighetti L,de Jong MC,Castillo F,Schulick RD,Parks RW,Choti MA,Wigmore SJ,Gruenberger T,Pawlik TM

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Talimogene laherparepvec (T-VEC) is the first injectable oncolytic viral therapy approved for in-transit melanoma metastasis, with a reported overall response rate (ORR) of 25% and complete response rate (CRR) of 10%. To ascertain the role of patient selection on outcomes in routine practice, we evaluated th...

journal_title：Annals of surgical oncology

authors： Masoud SJ,Hu JB,Beasley GM,Stewart JH 4th,Mosca PJ

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Phase III trials evaluating the role of secondary cytoreductive surgery (SCS) in recurrent ovarian cancer have pointed to the importance of patient selection. Two studies showed conflicting results regarding the benefit of SCS in BRCA1/2 mutation carriers. Our aim was to evaluate the impact of SCS on recurre...

journal_title：Annals of surgical oncology

authors： Estati FL,Pirolli R,de Alencar VTL,Ribeiro ARG,Formiga MN,Torrezan GT,Carraro DM,Guimarães APG,Baiocchi G,da Costa AABA

更新日期：2020-11-21 00:00:00

abstract：PURPOSE:Chemoradiation (CT/RT) followed by radical surgery (RS) may play a role in locally advanced cervical cancer (LACC) patients with suboptimal response to CT/RT or in low-income countries with limited access to radiotherapy. Our aim is to evaluate oncological and surgical outcomes of minimally invasive radical sur...

journal_title：Annals of surgical oncology

authors： Ferrandina G,Gallotta V,Federico A,Fanfani F,Ercoli A,Chiantera V,Cosentino F,Turco LC,Legge F,Anchora LP,Bizzarri N,Moroni R,Macchia G,Valentini V,Scambia G

更新日期：2020-11-09 00:00:00

abstract：BACKGROUND:The risk of colorectal cancer (CRC) in chronic kidney disease (CKD) patients relative to the general population is unknown. The aim of this population-based study was to investigate the risk of CRC in patients with CKD. METHODS:The study cohort included patients aged ≥18 years diagnosed with CKD between 200...

journal_title：Annals of surgical oncology

authors： Wu MY,Chang TC,Chao TY,Huang MT,Lin HW

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:During the breast lumpectomy procedure, surgeons traditionally elect to use either a superficial or full-thickness closure when sealing the wound depending on surgeon preference as well as desired outcomes. The purpose of this study was to examine dosimetric endpoints in patients with superficial versus full...

journal_title：Annals of surgical oncology

authors： Shaikh T,Narra V,Goyal S,Ahlawat S,Kirstein L,Kearney T,Haffty BG,Khan AJ

更新日期：2013-04-01 00:00:00

abstract：INTRODUCTION:The clinical significance of isolated tumor cells (ITC) in peripheral blood (PB) and bone marrow (BM) as predictive markers in the recurrence or metastasis of breast cancer has not yet been determined. In the current study, we focused on the urokinase plasminogen activator receptor (u-PAR) gene as a powerf...

journal_title：Annals of surgical oncology

authors： Mimori K,Kataoka A,Yamaguchi H,Masuda N,Kosaka Y,Ishii H,Ohno S,Mori M

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:Reasons for variable utilization of adjuvant chemotherapy (ACT) for colon cancer have not been well described. We report medical oncology (MO) referral patterns and subsequent use of ACT. METHODS:Treatment records were linked to the population-based Ontario Cancer Registry to describe MO referral and ACT use a...

journal_title：Annals of surgical oncology

authors： Chandhoke G,Wei X,Nanji S,Biagi J,Peng Y,Krzyzanowska M,Mackillop WJ,Booth CM

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Hepatitis B (HBV)-associated hepatocellular carcinoma (HCC) is often associated with alpha-fetoprotein (AFP) production. Although serum AFP has been demonstrated to be a prognostic factor for patient survival, optimal cutoff levels remain unclear. METHODS:Patients with HBV-associated HCC treated by primary ...

journal_title：Annals of surgical oncology

authors： Blank S,Wang Q,Fiel MI,Luan W,Kim KW,Kadri H,Mandeli J,Hiotis SP

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:The prognostic value of c-erbB-2 and vascular endothelial growth factor (VEGF) expression in colorectal liver metastases (CLM) is unclear. The purpose of this study was to clarify the relationship of c-erbB-2 and VEGF with the clinicopathological parameters and the survival results in CLM. METHODS:For 44 pa...

journal_title：Annals of surgical oncology

authors： Chen J,Li Q,Wang C,Wu J,Zhao G

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Sensitive biomarkers are necessary for risk classification of patients with gastric cancer (GC), especially ones at risk of distant metastases. Melanoma-associated antigen (MAGE)-D2 has been reported to play a role in the process of cell adhesion and metastatic potential of tumor cells in colorectal cancer. ...

journal_title：Annals of surgical oncology

authors： Kanda M,Nomoto S,Oya H,Takami H,Shimizu D,Hibino S,Hashimoto R,Kobayashi D,Tanaka C,Yamada S,Fujii T,Nakayama G,Sugimoto H,Koike M,Fujiwara M,Kodera Y

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Although the National Comprehensive Cancer Network (NCCN) guidelines recommend use of lymph node dissection (LND) in patients with pancreatic neuroendocrine tumors (pNETs) > 2 cm, there is limited evidence to support the association between use of LND and overall survival (OS). METHODS:Patients with resecte...

journal_title：Annals of surgical oncology

authors： Mao R,Zhao H,Li K,Luo S,Turner M,Cai JQ,Blazer D 3rd

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Adjuvant chemoradiotherapy improved survival in patients with resected gastric adenocarcinoma in the Southwest Oncology Group/Intergroup 0116 trial. Our objective was to examine the impact of adjuvant treatment on overall survival (OS) in the general population. METHODS:Patients 18-85 years old who had unde...

journal_title：Annals of surgical oncology

authors： Coburn NG,Govindarajan A,Law CH,Guller U,Kiss A,Ringash J,Swallow CJ,Baxter NN

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:The status of the axillary lymph nodes in nonmetastatic lymph node-positive breast cancer (BC) patients remains the single most important determinant of overall survival (OS). Although the absolute number of nodes involved with cancer is important for prognosis, the role of the total number of excised nodes ...

journal_title：Annals of surgical oncology

authors： Hatoum HA,Jamali FR,El-Saghir NS,Musallam KM,Seoud M,Dimassi H,Abbas J,Khalife M,Boulos FI,Tawil AN,Geara FB,Salem Z,Shamseddine AA,Al-Feghali K,Shamseddine AI

更新日期：2009-12-01 00:00:00

abstract：PURPOSE:Rates of both unilateral (UM) and contralateral prophylactic mastectomy (CPM) for unilateral early-stage breast cancer (ESBC) have been increasing since 2003. Recent studies suggest that this increase may be due to women choosing UM and CPM because of fear. We conducted an in-depth qualitative study to identify...

journal_title：Annals of surgical oncology

authors： Covelli AM,Baxter NN,Fitch MI,McCready DR,Wright FC

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Not all patients respond equally to neoadjuvant chemoradiotherapy (nCRT), with subsequent effects on survival. The systemic inflammatory response has been shown to predict long-term outcomes in colorectal cancer. The current study examined the association between systemic inflammation and nCRT in patients wi...

journal_title：Annals of surgical oncology

authors： Dreyer SB,Powell AG,McSorley ST,Waterston A,Going JJ,Edwards J,McMillan DC,Horgan PG

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:The external branch of the superior laryngeal nerve (EBSLN) is at risk during thyroid surgery. Despite meticulous dissection and visualization, the EBSLN can be mistaken for other structures. The nerve integrity monitor (NIM) allows EBSLN confirmation with cricothyroid twitch on stimulation. AIMS:The aim of...

journal_title：Annals of surgical oncology

authors： Glover AR,Norlén O,Gundara JS,Morris M,Sidhu SB

更新日期：2015-01-01 00:00:00

abstract：: ...

journal_title：Annals of surgical oncology

authors： James TA

更新日期：2018-12-01 00:00:00

abstract：: ...

journal_title：Annals of surgical oncology

authors： Turaga KK,Clark Gamblin T,Richard Alexander H,Edwards R,Bartlett DL

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Laparoscopy-assisted distal gastrectomy (LADG) for gastric cancer may prevent the development of an impaired nutritional status due to reduced surgical stress compared with open distal gastrectomy (ODG). METHODS:This study was performed as an exploratory analysis of a phase III trial comparing LADG and ODG ...

journal_title：Annals of surgical oncology

authors： Aoyama T,Yoshikawa T,Hayashi T,Hasegawa S,Tsuchida K,Yamada T,Cho H,Ogata T,Fujikawa H,Yukawa N,Oshima T,Rino Y,Masuda M

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:The Affordable Care Act (ACA) was instated on 23 March 2010 to improve healthcare quality, reduce costs, and increase access. The Pretty in Pink Foundation (PIPF), a non-profit 501(C)(3) organization in North Carolina, provides financial assistance and in-kind support to individuals seeking help with breast ...

journal_title：Annals of surgical oncology

authors： Obeng-Gyasi S,Tolnitch L,Greenup RA,Shelley Hwang E

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:In case of liver tumors invading the middle hepatic vein (MHV) at the hepatocaval confluence (HC) major resection is recommended. We describe a new ultrasound-guided conservative operation for patients with colorectal liver metastasis (CLM) invading the MHV at the HC. METHODS:The case of a 65-year-old woman...

journal_title：Annals of surgical oncology

authors： Torzilli G,Botea F,Donadon M,Cimino M,Del Fabbro D,Palmisano A

更新日期：2010-02-01 00:00:00

abstract：AIMS:To determine the incidence of lymph node (LN) metastasis in patients with apparently early carcinosarcoma of the uterus, to analyze the clinicopathologic factors associated with LN metastasis, and to evaluate the role of pelvic and/or para-aortic lymphadenectomy in treatment of such conditions. METHODS:We retrosp...

journal_title：Annals of surgical oncology

authors： Park JY,Kim DY,Kim JH,Kim YM,Kim YT,Nam JH

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Routine cross-sectional imaging for staging of early-stage cutaneous melanoma is not recommended. This study sought to investigate the use of imaging for staging of cutaneous melanoma in the United States. METHODS:Patients with nonmetastatic cutaneous melanoma newly diagnosed between 2000 and 2007 were iden...

journal_title：Annals of surgical oncology

authors： Wasif N,Etzioni D,Haddad D,Gray RJ,Bagaria SP,Pockaj BA

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine the prognostic significance of preoperative carcinoembryonic antigen (CEA) and carbohydrate antigen (CA) 19-9 levels in patients with resectable gastric cancer (GC). PATIENTS AND METHODS:Patients who underwent a radical resection for GC at the Fujian Medical University ...

journal_title：Annals of surgical oncology

authors： Lin JX,Wang W,Lin JP,Xie JW,Wang JB,Lu J,Chen QY,Cao LL,Lin M,Tu R,Zheng CH,Huang CM,Zhou ZW,Li P

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:This study aims to elucidate whether increasing the number of examined lymph nodes (NELN) is mandatory for the accurate prognosis of node-negative gastric cancer (GC) patients after curative gastrectomy in Eastern countries (China and Japan). METHODS:The clinicopathological data of 2455 GC patients (includi...

journal_title：Annals of surgical oncology

authors： Deng J,Yamashita H,Seto Y,Liang H

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:L1, a new target gene for Wnt/beta-catenin-TCF signaling, has been identified in the invasive front of colorectal cancer cells in vitro study. The L1 molecule is localized on the cell surface in tumor tissues, accompanied with loss of beta-catenin and E-cadherin. However, such association between L1 expressi...

journal_title：Annals of surgical oncology

authors： Boo YJ,Park JM,Kim J,Chae YS,Min BW,Um JW,Moon HY

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has improved the survival in selected colorectal cancer patients with peritoneal metastases. In these patients, the risk of a low anastomosis is sometimes diminished through the creation of a colostomy. Currently, the morbidity...

journal_title：Annals of surgical oncology

authors： de Cuba EM,Verwaal VJ,de Hingh IH,van Mens LJ,Nienhuijs SW,Aalbers AG,Bonjer HJ,te Velde EA

更新日期：2014-03-01 00:00:00