Is hepatic resection for large or multinodular hepatocellular carcinoma justified? Results from a multi-institutional database.

abstract：BACKGROUND:Although the honeycomb microcystic type is common and typical for a serous cystic tumor (SCT), clinical and radiological features are diverse. Systematic classification of SCT subtypes is not well established. The purpose of this study was to classify the subtypes of SCT and to clarify its clinical and patho...

journal_title：Annals of surgical oncology

authors： Lee SE,Kwon Y,Jang JY,Kim YH,Hwang DW,Kim MA,Kim SH,Kim SW

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:The extent of neck dissection (ND) appropriate for necks yielding clinical evidence of metastases of papillary thyroid carcinoma (PTC) is controversial. The need for level IIb lymph node (LN) dissection is particularly uncertain in view of its association with postoperative shoulder dysfunction. In the prese...

journal_title：Annals of surgical oncology

authors： Koo BS,Yoon YH,Kim JM,Choi EC,Lim YC

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Heat shock protein 27 (hsp-27) is overexpressed in approximately 67% pure ductal carcinoma in situ (DCIS), in approximately 50% DCIS associated with invasive ductal carcinoma (IDC), and in approximately 25% IDC alone. If this decrease in hsp-27 expression has a role in the progression of malignancy in IDC, w...

journal_title：Annals of surgical oncology

authors： Storm FK,Mahvi DM,Gilchrist KW

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:Resectability rates for extrahepatic cholangiocarcinoma have increased over time, but long-term survival after resection alone with curative intent remains poor. Recent series suggest improved survival with adjuvant therapy. Patient subsets benefiting most from adjuvant therapy have not been clearly defined....

journal_title：Annals of surgical oncology

authors： Ecker BL,Vining CC,Roses RE,Maggino L,Lee MK,Drebin JA,Fraker DL,Vollmer CM Jr,Datta J

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Dermatofibrosarcoma protuberans (DFSP) is a dermal sarcoma often diagnosed by excision biopsy, and is often incompletely excised, with high recurrence rates. Traditional wide excision involves resection margins of 2-4 cm, often resulting in morbid procedures requiring surgical reconstruction. An alternative ...

journal_title：Annals of surgical oncology

authors： Snow H,Davies E,Strauss DC,Smith M,Hayes AJ

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:It has been reported that the abnormal activation of receptor tyrosine kinases is associated with the development of many human carcinomas and the high activation of EGFR and Met mediates the tumorigenicity of laryngeal carcinoma. In this study, we have done the therapeutic efficacy of ME22S (a novel EGFR/Met b...

journal_title：Annals of surgical oncology

authors： Lee BS,Kim HJ,Hwang JW,Cheong KH,Kim KA,Cha HY,Lee JM,Kim CH

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Sentinel lymph node mapping (SLNM) and neoadjuvant chemotherapy are becoming established components of therapy for selected patients with breast carcinoma. However, neoadjuvant therapy has been considered a relative contraindication to SLNM. In an effort to learn whether patients who have received preoperati...

journal_title：Annals of surgical oncology

authors： Miller AR,Thomason VE,Yeh IT,Alrahwan A,Sharkey FE,Stauffer J,Otto PM,McKay C,Kahlenberg MS,Phillips WT,Cruz AB Jr

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Thick (>or=4-mm) primary melanomas are believed to be associated with a high incidence of occult distant metastases. The use of sentinel lymph node (SLN) mapping and biopsy in the treatment lesions has been questioned. METHODS:A retrospective review of a computerized database identified 114 patients who und...

journal_title：Annals of surgical oncology

authors： Carlson GW,Murray DR,Hestley A,Staley CA,Lyles RH,Cohen C

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Persistent or recurrent primary hyperparathyroidism (1 degrees HPTH) is ideally treated with limited dissection, based on accurate localization, to minimize operative risks. To accurately localize parathyroid tissue, we employed ultrasound-guided fine needle aspiration (US FNA) with an on-site rapid parathyr...

journal_title：Annals of surgical oncology

authors： Maser C,Donovan P,Santos F,Donabedian R,Rinder C,Scoutt L,Udelsman R

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Neoadjuvant chemotherapy (NCT) for breast cancer might change the number of involved and detected nodes in axillary lymph node dissections (ALND). In this study, we analyzed whether the number of dissected nodes and the lymph node ratio (LNR, defined as the proportion of involved nodes in dissected nodes) wo...

journal_title：Annals of surgical oncology

authors： Chen S,Liu Y,Huang L,Chen CM,Wu J,Shao ZM

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The American Joint Committee on Cancer (AJCC) substantially changed the staging of cutaneous squamous cell carcinoma (cSCC) in the 7th edition of its staging manual. We aim to compare the 7th edition AJCC staging of nodal metastases from cSCC with the N1S3 staging system. METHODS:Analysis of 603 patients fr...

journal_title：Annals of surgical oncology

authors： Clark JR,Rumcheva P,Veness MJ

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Isolated regional failure of nasopharyngeal carcinoma (NPC) after primary treatment is traditionally treated with radical neck dissection (RND). The roles of modified radical neck dissection (MRND) and postoperative radiotherapy after salvage surgery currently remain unclear. METHODS:Medical records from ou...

journal_title：Annals of surgical oncology

authors： Lo WC,Wang CP,Ko JY,Lou PJ,Yang TL,Wang CW,Hu YL,Chen TC

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to investigate the diagnostic and prognostic value of circulating endothelial cell (CEC), a potential surrogate of tumor angiogenesis, in malignant pleural mesothelioma (MPM). METHODS:We prospectively evaluated CEC count in 4.0 mL of peripheral blood sampled from patients with ...

journal_title：Annals of surgical oncology

authors： Yoneda K,Tanaka F,Kondo N,Orui H,Hashimoto M,Takuwa T,Matsumoto S,Okumura Y,Tsubota N,Sato A,Tsujimura T,Kuribayashi K,Fukuoka K,Nakano T,Hasegawa S

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel approach to delivering intraperitoneal chemotherapy (IPC) as a pressurized aerosol. One of the assumed advantages is the homogeneous drug distribution in the intraperitoneal cavity compared with conventional liquid in situ chemotherapy. Howe...

journal_title：Annals of surgical oncology

authors： Khosrawipour V,Khosrawipour T,Diaz-Carballo D,Förster E,Zieren J,Giger-Pabst U

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Findings show that 5-10 % of women with a diagnosis of breast cancer (BCa) have actionable genetic mutations. The National Comprehensive Cancer Network guidelines for testing to detect BRCA1/2 mutations include personal history (PH) variables such as age of 45 years or younger and a family history (FH) varia...

journal_title：Annals of surgical oncology

authors： Kishan AU,Gomez CL,Dawson NA,Dvorak R,Foster NM,Hoyt A,Hurvitz SA,Kusske A,Silver EL,Tseng C,McCloskey SA

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Cholangiocarcinoma can be classified in intrahepatic cholangiocarcinoma (ICC) and perihilar cholangiocarcinoma (PCC). Moreover, PCC includes two different forms: extrahepatic (EH) PCC, which arises from the perihilar EH large ducts, and intrahepatic (IH) PCC, in which a significant liver mass invades the per...

journal_title：Annals of surgical oncology

authors： Ruzzenente A,Fassan M,Conci S,Simbolo M,Lawlor RT,Pedrazzani C,Capelli P,D'Onofrio M,Iacono C,Scarpa A,Guglielmi A

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Major hepatectomy for intrahepatic cholangiocarcinoma (ICC) sometimes involves resection of major hepatic veins, which might result in the future liver remnant (FLR) congestion. The necessity and efficacy of resection and reconstruction of the middle hepatic vein (MHV) during right or left hemihepatectomy fo...

journal_title：Annals of surgical oncology

authors： Miyata A,Sakamoto Y,Yamamoto S,Akamatsu N,Arita J,Kaneko J,Hasegawa K,Kokudo N

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Recent population-based studies have highlighted a disproportionate increase in the incidence of rectal cancer among adults younger than aged 50 years. To determine whether different intervention and surveillance strategies might be needed for younger patients, the patterns of care and oncologic outcomes amo...

journal_title：Annals of surgical oncology

authors： You YN,Dozois EJ,Boardman LA,Aakre J,Huebner M,Larson DW

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:The 1998 post-operative radiotherapy meta-analysis for lung cancer showed a survival detriment associated with radiation for stage I-II resected non-small cell lung cancer (NSCLC), but has been criticized for including antiquated radiation techniques. We analyzed the National Cancer Database (NCDB) to determ...

journal_title：Annals of surgical oncology

authors： Pezzi TA,Mohamed AS,Fuller CD,Blanchard P,Pezzi C,Sepesi B,Hahn SM,Gomez DR,Chun SG

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Poly(ADP-ribose) polymerase (PARP) is an important regulator of programmed cell death in response to alkylating agents such as temozolomide (TMZ). The goal of this study was to determine if a systemically administered PARP-inhibitor (INO-1001) could augment the efficacy of TMZ in a rat model of extremity mal...

journal_title：Annals of surgical oncology

authors： Toshimitsu H,Yoshimoto Y,Augustine CK,Padussis JC,Yoo JS,Angelica Selim M,Pruitt SK,Friedman HS,Ali-Osman F,Tyler DS

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Cytotoxic T lymphocyte-associated antigen (CTLA)-4 can inhibit T-cell responses and is involved in tolerance against self antigens. We previously reported autoimmune manifestations and objective cancer regressions in patients with metastatic melanoma treated with CTLA-4 blockade. The possibility of activatin...

journal_title：Annals of surgical oncology

authors： Maker AV,Phan GQ,Attia P,Yang JC,Sherry RM,Topalian SL,Kammula US,Royal RE,Haworth LR,Levy C,Kleiner D,Mavroukakis SA,Yellin M,Rosenberg SA

更新日期：2005-12-01 00:00:00

abstract：PURPOSE:We sought to examine how splenectomy as part of up-front cytoreductive surgery in ovarian cancer influences the postoperative course and affects survival. METHODS:We reviewed cases of ovarian cancer diagnosed at Massachusetts General Hospital from 1994 to 2008 and found 44 patients who had a splenectomy as par...

journal_title：Annals of surgical oncology

authors： McCann CK,Growdon WB,Munro EG,Del Carmen MG,Boruta DM,Schorge JO,Goodman A

更新日期：2011-10-01 00:00:00

abstract：:The surveillance of breast cancer patients after potentially curative treatment may result in the identification of locoregional or distant recurrence. While many patients expect frequent imaging studies to monitor for recurrence, there are no data supporting aggressive imaging surveillance beyond mammography. However...

journal_title：Annals of surgical oncology

authors： Leitch AM

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Response to chemotherapy and anatomical spread are significant prognostic factors in patients with esophageal squamous cell carcinoma (ESCC) treated by chemotherapy then surgery. Predicting the response to chemotherapy would allow significant optimization of cancer treatment. METHODS:Genomic mutation and pr...

journal_title：Annals of surgical oncology

authors： Yamasaki M,Miyata H,Fujiwara Y,Takiguchi S,Nakajima K,Nishida T,Yasuda T,Matsuyama J,Mori M,Doki Y

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:The National Comprehensive Cancer Network (NCCN) recommends that at least 15 lymph nodes (LNs) be removed during radical gastrectomy. This study aims to investigate the optimal number of LNs resected for radical gastrectomy. PATIENTS AND METHODS:From September 2008 to March 2015, a total of 1990 gastric can...

journal_title：Annals of surgical oncology

authors： Zheng G,Feng F,Guo M,Xu G,Liu S,Liu Z,Sun L,Hong L,Yang J,Lian X,Fan D,Zhang H

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:An oncolytic herpes simplex virus type 1 mutant (HF10) has been isolated and evaluated for antitumor efficacy in a syngeneic immunocompetent mouse model, where it was effective against cancer and conferred resistance to rechallenge with tumor cells in all surviving mice. Several studies have shown that HF10 ...

journal_title：Annals of surgical oncology

authors： Kimata H,Imai T,Kikumori T,Teshigahara O,Nagasaka T,Goshima F,Nishiyama Y,Nakao A

更新日期：2006-08-01 00:00:00

abstract：PURPOSE:Rates of both unilateral (UM) and contralateral prophylactic mastectomy (CPM) for unilateral early-stage breast cancer (ESBC) have been increasing since 2003. Recent studies suggest that this increase may be due to women choosing UM and CPM because of fear. We conducted an in-depth qualitative study to identify...

journal_title：Annals of surgical oncology

authors： Covelli AM,Baxter NN,Fitch MI,McCready DR,Wright FC

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Extending the original criteria of the Chemoradiotherapy for Oesophageal Cancer followed by Surgery Study (CROSS) in daily practice may increase the treatment outcome of esophageal cancer (EC) patients. This retrospective national cohort study assessed the impact on the pathologic complete response (pCR) rat...

journal_title：Annals of surgical oncology

authors： Wang HH,de Heer EC,Hulshoff JB,Kats-Ugurlu G,Burgerhof JGM,van Etten B,Plukker JTM,Hospers GAP,Dutch Upper Gastrointestinal Cancer Audit (DUCA) Group.

更新日期：2020-11-28 00:00:00

abstract：BACKGROUND:The utility of sentinel lymph node biopsy (SLNB) for desmoplastic melanoma (DM) is debated. We describe a large single-institution experience with SLNB for DM to determine clinicopathologic factors predictive of SLN metastasis. METHODS:Retrospective review identified 205 patients with DM who underwent SLNB ...

journal_title：Annals of surgical oncology

authors： Han D,Zager JS,Yu D,Zhao X,Walls B,Marzban SS,Rao NG,Sondak VK,Messina JL

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Subtotal thyroidectomy or lobectomy without radioactive iodide ((131)I) treatment is sufficient for postoperative treatment of incidental papillary thyroid microcarcinoma (PTMC). Aggressive surgical treatment with (131)I therapy is indicated for nonincidental PTMC. METHODS:This is a retrospective analysis o...

journal_title：Annals of surgical oncology

authors： Lin JD,Kuo SF,Chao TC,Hsueh C

更新日期：2008-08-01 00:00:00