Importin-α1 as a novel prognostic target for hepatocellular carcinoma.

abstract：BACKGROUND:CD44, a cancer stem cell surface marker, is associated with treatment resistance and prognosis in some cancers. In the present study, we examined the predictive value of CD44 in muscle-invasive bladder cancer (MIBC). METHODS:We retrospectively analyzed the clinical outcomes of 105 MIBC patients and correlat...

journal_title：Annals of surgical oncology

authors： Wu CT,Lin WY,Chen WC,Chen MF

更新日期：2018-11-01 00:00:00

abstract：:The Chicago Consensus Working Group provides multidisciplinary recommendations for the management of colorectal cancer specifically as it relates to the management of peritoneal surface malignancy. These guidelines are developed with input from leading experts including surgical oncologists, medical oncologists, patho...

journal_title：Annals of surgical oncology

authors： Chicago Consensus Working Group.

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:Treatment of synovial sarcoma (SS) is challenging because of its unpredictable clinical behavior. We reviewed our institutional experience with pediatric SS to identify prognostic indicators and survival outcomes. METHODS:We retrospectively reviewed all pediatric/adolescent patients (age<22 years) with confirm...

journal_title：Annals of surgical oncology

authors： Stanelle EJ,Christison-Lagay ER,Healey JH,Singer S,Meyers PA,La Quaglia MP

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Surgery is the most important treatment for nonmetastatic breast cancer; however, the utilization of modern surgical techniques in management of breast cancer in mainland China has not been reported. METHODS:The medical records of 5887 consecutive breast cancer patients treated surgically in the past 16 yea...

journal_title：Annals of surgical oncology

authors： Yu KD,Di GH,Wu J,Lu JS,Shen KW,Shen ZZ,Shao ZM

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Although advocated by some, minimally invasive adrenalectomy (MIA) for adrenocortical carcinoma (ACC) is controversial. Moreover, the oncologic implications for patients requiring conversion to an open procedure during attempted MIA for ACC are not extensively reported. PATIENTS AND METHODS:The National Can...

journal_title：Annals of surgical oncology

authors： Delozier OM,Stiles ZE,Deschner BW,Drake JA,Deneve JL,Glazer ES,Tsao MW,Yakoub D,Dickson PV

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Contralateral prophylactic mastectomy (CPM) is expected to add surgical morbidity but this incremental risk has not yet been defined. We sought to quantify the additional risks associated with CPM and determine how these risks influence the time to adjuvant therapy. METHODS:We identified women undergoing ma...

journal_title：Annals of surgical oncology

authors： Eck DL,Perdikis G,Rawal B,Bagaria S,McLaughlin SA

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Despite decreasing rates of subsequent contralateral breast cancer after diagnosis of unilateral primary breast cancer, the proportion of patients electing contralateral prophylactic mastectomy (CPM) is increasing. Our aim was to identify risk factors associated with the identification of occult malignancy (...

journal_title：Annals of surgical oncology

authors： Erdahl LM,Boughey JC,Hoskin TL,Degnim AC,Hieken TJ

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine the feasibility and optimal timing of quality of life assessment for patients undergoing palliative surgical evaluation. METHODS:Patients with an advanced malignancy undergoing consultation for palliative surgical intervention were prospectively enrolled from Novem...

journal_title：Annals of surgical oncology

authors： Badgwell B,Krouse R,Cormier J,Guevara C,Klimberg VS,Ferrell B

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Neoadjuvant chemotherapy (NCT) for breast cancer might change the number of involved and detected nodes in axillary lymph node dissections (ALND). In this study, we analyzed whether the number of dissected nodes and the lymph node ratio (LNR, defined as the proportion of involved nodes in dissected nodes) wo...

journal_title：Annals of surgical oncology

authors： Chen S,Liu Y,Huang L,Chen CM,Wu J,Shao ZM

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Thirty-day mortality after surgery for colorectal cancer may vastly underestimate 1-year mortality. This study aimed to quantify the excess mortality in the first postoperative year of stage I-III colorectal cancer patients and to identify risk factors for excess mortality. METHODS:All 2,131 patients who we...

journal_title：Annals of surgical oncology

authors： Gooiker GA,Dekker JW,Bastiaannet E,van der Geest LG,Merkus JW,van de Velde CJ,Tollenaar RA,Liefers GJ

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:With the exception of papillary and follicular thyroid cancer, malignant cancers of the thyroid, parathyroid, adrenal, and endocrine pancreas are uncommon. These rare malignancies present a challenge to both the clinician and patient, because few data exist on their incidence or survival. We analyzed the incide...

journal_title：Annals of surgical oncology

authors： James BC,Aschebrook-Kilfoy B,Cipriani N,Kaplan EL,Angelos P,Grogan RH

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The risk of axillary failure (AF) after accelerated partial breast irradiation (APBI) using MammoSite brachytherapy is unknown and has been source of concern as the axillary region is not treated with this technique. We aimed to determine the rate of AF in patients treated with APBI and identify factors asso...

journal_title：Annals of surgical oncology

authors： Aburabia M,Roses RE,Kuerer HM,Fine R,Beitsch PD,Goyal S,Haffty B,Lyden M,Vicini FA

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:Despite advances in therapy for the treatment of metastatic colorectal cancer, many patients die of hepatic disease. Current immunotherapeutic strategies are likely limited by inhibitory signals from the tumor. To successfully eliminate tumor deposits within an organ, an appropriate immunologic milieu to amplif...

journal_title：Annals of surgical oncology

authors： Olino K,Wada S,Edil BH,Pan X,Meckel K,Weber W,Slansky J,Tamada K,Lauer P,Brockstedt D,Pardoll D,Schulick R,Yoshimura K

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:The efficacy of chemoprevention for breast cancer risk reduction has been demonstrated in randomized controlled trials; however, use remains low. We sought to determine whether uptake differed by risk factors, and to identify reasons for refusal and termination. METHODS:Women seen in a high-risk c...

journal_title：Annals of surgical oncology

authors： Flanagan MR,Zabor EC,Stempel M,Mangino DA,Morrow M,Pilewskie ML

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Considering the typical rapid progression and high mortality of pancreatic cancer (PC), early detection may lead to an improved outcome. To date, there is no safe, sensitive, and cost-effective screening strategy to detect PC. Currently, screening is focused on individuals at the highest risk of developing P...

journal_title：Annals of surgical oncology

authors： Catts ZA,Baig MK,Milewski B,Keywan C,Guarino M,Petrelli N

更新日期：2016-05-01 00:00:00

abstract：: ...

journal_title：Annals of surgical oncology

authors： Takamori S,Toyokawa G

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:Basal subtype, as approximated by the triple-negative phenotype (ER-PR-Her2-), has correlated with higher LRR in recent studies. Indications for postmastectomy RT (PMRT) in women with 0-3 positive lymph nodes remain unclear. We evaluated the importance of biologic subtype in a cohort of women with LRR after mas...

journal_title：Annals of surgical oncology

authors： Khan AJ,Milgrom SA,Barnard N,Higgins SA,Moran M,Shahzad H,Kim S,Goyal S,Al-Faraj F,Kirstein L,Kearney T,Haffty BG

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:To determine the effect of flap reconstruction on perineal complications in locally advanced rectal cancers (LARC) and locally recurrent rectal cancers (LRRC). Prior studies have suggested that flap reconstruction may decrease wound complications after ablative surgery for rectal cancer but are limited by sm...

journal_title：Annals of surgical oncology

authors： Davidge KM,Raghuram K,Hofer SO,Ferguson PC,Wunder JS,Swallow CJ,Zhong T

更新日期：2014-06-01 00:00:00

abstract：INTRODUCTION:Regional nodal status is the most powerful predictor of recurrence and survival in women with breast cancer. Lymphatic mapping and sentinel lymph node (SLN) biopsy have been found to accurately predict the regional nodal status. Preoperative lymphoscintigraphy has been used in melanoma patients to identify...

journal_title：Annals of surgical oncology

authors： Dupont EL,Kamath VJ,Ramnath EM,Shivers SC,Cox C,Berman C,Leight GS Jr,Ross MI,Blumencranz P,Reintgen DS,DOD Breast Lymphatic Mapping Trial Investigators.

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Malignant pleural effusions are seen frequently in clinical practice and are most commonly caused by breast cancer and lung cancer. Standard treatment usually consists of complete drainage of the pleural space via a chest tube and instillation of a pleural irritant to obtain pleural symphysis. In a majority ...

journal_title：Annals of surgical oncology

authors： Fry WA,Khandekar JD

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Sentinel lymph node (SLN) mapping for melanoma and breast cancer has greatly enhanced the identification of micrometastases in many patients, thereby upstaging a subset of these patients. The purpose of this study was to see if SLN mapping technique could be used to identify SLNs in colorectal cancer and to ...

journal_title：Annals of surgical oncology

authors： Saha S,Wiese D,Badin J,Beutler T,Nora D,Ganatra BK,Desai D,Kaushal S,Nagaraju M,Arora M,Singh T

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:The goal of this multicenter study was to clarify the determinants of local excision for patients with T1-T2 lower rectal cancer. METHODS:Data from 567 consecutive patients who underwent radical resection for T1-T2 lower rectal cancer at 12 institutions between 1991 and 1998 were reviewed. Rates of lymph no...

journal_title：Annals of surgical oncology

authors： Kobayashi H,Mochizuki H,Kato T,Mori T,Kameoka S,Shirouzu K,Saito Y,Watanabe M,Morita T,Hida J,Ueno M,Ono M,Yasuno M,Sugihara K

更新日期：2010-04-01 00:00:00

abstract：:Intraoperative radiotherapy (IORT) is increasingly used worldwide. Breast cancer is the most rapidly growing indication for IORT, approaching 70-80% of cases in most centers. This report reviews the theoretical background and clinical use of IORT for primary and metastasized breast cancer. There are established applic...

journal_title：Annals of surgical oncology

authors： Wenz F

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:NIMA-related kinase 2 (NEK2), an enzyme involved in the development and progression of cancer, is abnormally expressed in a wide variety of human cancers, including colorectal cancer (CRC), and is known to have roles in cell division and mitotic regulation through centrosome splitting. We investigated the cl...

journal_title：Annals of surgical oncology

authors： Takahashi Y,Iwaya T,Sawada G,Kurashige J,Matsumura T,Uchi R,Ueo H,Takano Y,Eguchi H,Sudo T,Sugimachi K,Yamamoto H,Doki Y,Mori M,Mimori K

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Lymph node metastasis is widely accepted as one of the most important determinants of prognosis in colorectal cancer (CRC) patients. Therefore, there is an urgent need to identify molecular markers that can be used to predict lymph node metastasis. MATERIALS AND METHODS:Candidate genes were found using LMD ...

journal_title：Annals of surgical oncology

authors： Ozawa H,Iwatsuki M,Mimori K,Sato T,Johansson F,Toh H,Watanabe M,Mori M

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Distal pancreatectomy with celiac axis resection (DP-CAR) is a treatment option for selected patients with pancreatic cancer involving the celiac axis. A recent multicenter European study reported a 90-day mortality rate of 16%, highlighting the importance of patient selection. The authors constructed a risk...

journal_title：Annals of surgical oncology

authors： Klompmaker S,Peters NA,van Hilst J,Bassi C,Boggi U,Busch OR,Niesen W,Van Gulik TM,Javed AA,Kleeff J,Kawai M,Lesurtel M,Lombardo C,Moser AJ,Okada KI,Popescu I,Prasad R,Salvia R,Sauvanet A,Sturesson C,Weiss MJ,Zeh

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate outcomes after breast-conserving surgery (BCS) and intraoperative radiotherapy (IORT), and to identify risk factors associated with complications. MATERIALS/METHODS:We evaluated patients with early-stage breast cancer treated from January 1, 2011 to January 31, 2014 with...

journal_title：Annals of surgical oncology

authors： Rakhra S,Bethke K,Strauss J,Hayes JP,Hansen N,Khan SA,Helenowski I,Donnelly ED

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Limited data exist that describe the long-term outcomes from additional surgery following non-curative endoscopic resection (ER) of early gastric cancer (EGC) in older people. This study aimed to determine the appropriate treatment strategy for these patients. METHODS:We analyzed data from 2895 patients who...

journal_title：Annals of surgical oncology

authors： Pyo JH,Lee H,Min BH,Lee JH,Kim KM,Yoo H,Ahn S,An JY,Choi MG,Lee JH,Sohn TS,Bae JM,Kim JJ,Kim S

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine whether routine biologic tumor markers can predict lymph node status. The authors attempted to discover whether predictors of axillary lymph node metastasis based on biologic characteristic of primary breast cancers exist. METHODS:Eight hundred and fifty-one patien...

journal_title：Annals of surgical oncology

authors： Velanovich V,Szymanski W

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:The prognosis of biliary tract cancer (BTC) is unfavorable due to its chemoresistance. Hypoxia triggers epithelial-to-mesenchymal transition (EMT), which is closely related to drug resistance. In this study, we focused on the functional roles of procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2), a h...

journal_title：Annals of surgical oncology

authors： Okumura Y,Noda T,Eguchi H,Sakamoto T,Iwagami Y,Yamada D,Asaoka T,Wada H,Kawamoto K,Gotoh K,Kobayashi S,Takeda Y,Tanemura M,Umeshita K,Doki Y,Mori M

更新日期：2018-11-01 00:00:00