Phosphatase and tensin analog gene overexpression engenders cellular death in human malignant mesothelioma cells via inhibition of AKT phosphorylation.

abstract：:Preoperative needle diagnosis (PND) is being considered as a quality measure in breast cancer surgery. This criterion has not been thoroughly evaluated in the literature. The purpose of this study is to assess ease of access to these data and rate of compliance in a tertiary care center. We retrospectively reviewed al...

journal_title：Annals of surgical oncology

authors： Pocock B,Taback B,Klein L,Joseph KA,El-Tamer M

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Identification of melanoma patients who need completion lymphadenectomy and adjuvant treatment after positive sentinel lymph node (SLN) biopsy would be a fundamental step forward toward personalized medicine. This study tested the hypothesis that the microscopic features of metastatic SLNs might predict not ...

journal_title：Annals of surgical oncology

authors： Rossi CR,De Salvo GL,Bonandini E,Mocellin S,Foletto M,Pasquali S,Pilati P,Lise M,Nitti D,Rizzo E,Montesco MC

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Sentinel lymph node (SLN) mapping for melanoma and breast cancer has greatly enhanced the identification of micrometastases in many patients, thereby upstaging a subset of these patients. The purpose of this study was to see if SLN mapping technique could be used to identify SLNs in colorectal cancer and to ...

journal_title：Annals of surgical oncology

authors： Saha S,Wiese D,Badin J,Beutler T,Nora D,Ganatra BK,Desai D,Kaushal S,Nagaraju M,Arora M,Singh T

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:This study was designed to investigate the correlation between postoperative recurrence of hepatocellular carcinoma (HCC) and perioperative expression and dynamic changes in cancer stem cell (CSC) markers in tumors and peripheral blood. METHODS:In HCC patients who underwent curative resection (n = 64) or li...

journal_title：Annals of surgical oncology

authors： Choi GH,Kim GI,Yoo JE,Na DC,Han DH,Roh YH,Park YN,Choi JS

更新日期：2015-12-01 00:00:00

abstract：INTRODUCTION:Lymphadenectomy and thyroidectomy is standard treatment for medullary thyroid carcinoma (MTC), but the prognostic importance of the number of lymph nodes removed (lymph node yield, LNY) and the proportion of metastatic lymph nodes resected (metastatic lymph node ratio, MLNR) is unknown. We hypothesized tha...

journal_title：Annals of surgical oncology

authors： Leggett MD,Chen SL,Schneider PD,Martinez SR

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Laparoscopic versus open hepatocellular carcinoma (HCC) resection reduces morbidity without a compromise in oncologic safety.1-4 Moreover, in the subgroup of cirrhotic patients, a decreased risk of prolonged postoperative ascites and liver decompensation has been reported.5-7 METHODS: A 54-year-old homeless,...

journal_title：Annals of surgical oncology

authors： Vega EA,Nicolaescu DC,Salehi O,Kozyreva O,Vellayappan U,Ricklan D,McCarty J,Fontan F,Pomposelli F,Conrad C

更新日期：2020-04-01 00:00:00

abstract：:Adenocarcinoma of the pancreas continues to be a formidable disease. In the United States, patients who have had resected disease are generally offered adjuvant chemoradiation. The current National Comprehensive Cancer Network practice guidelines uniformly support this practice. We reviewed seven selected series to ev...

journal_title：Annals of surgical oncology

authors： Chu QD,Khushalani N,Javle MM,Douglass HO Jr,Gibbs JF

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:The patients with early gastric cancer who have undergone incomplete endoscopic resection (ER) generally need additional surgery because of the possibility of lymph node metastasis. The aim of study was to evaluate the optimal time interval from ER to additive surgery by evaluating the effect of time interva...

journal_title：Annals of surgical oncology

authors： Kim MJ,Kim JH,Lee YC,Kim JW,Choi SH,Hyung WJ,Noh SH,Youn YH,Park H,Lee SI

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The rising incidence of incidental thyroid carcinoma (ITC) detected during fluoro-2-deoxy-D: -glucose (FDG)-positron emission tomography (PET)/computed tomography (CT) scanning poses a challenge to clinicians. The present study aims to critically evaluate the clinicopathological characteristics of ITC detect...

journal_title：Annals of surgical oncology

authors： Law TT,Lang BH

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:The usefulness of enteral nutrition via a nasointestinal tube for patients who develop postoperative pancreatic fistula (POPF) after miscellaneous pancreatectomy procedures has been reported. However, no clear evidence regarding whether oral intake is possible during management of POPF after pancreatoduodene...

journal_title：Annals of surgical oncology

authors： Fujii T,Nakao A,Murotani K,Okamura Y,Ishigure K,Hatsuno T,Sakai M,Yamada S,Kanda M,Sugimoto H,Nomoto S,Takeda S,Morita S,Kodera Y

更新日期：2015-11-01 00:00:00

abstract：PURPOSE:Retroperitoneal sarcomas (RPS) are rare malignancies, comprising just 10-15 % of all soft-tissue sarcomas. These are challenging tumors to treat, with surgical resection being the only modality capable of providing a cure. This study analyzed the management and survival of patients resected at a large academic ...

journal_title：Annals of surgical oncology

authors： Bremjit PJ,Jones RL,Chai X,Kane G,Rodler ET,Loggers ET,Pollack SM,Pillarisetty VG,Mann GN

更新日期：2014-07-01 00:00:00

abstract：PURPOSE:Chemoradiation (CT/RT) followed by radical surgery (RS) may play a role in locally advanced cervical cancer (LACC) patients with suboptimal response to CT/RT or in low-income countries with limited access to radiotherapy. Our aim is to evaluate oncological and surgical outcomes of minimally invasive radical sur...

journal_title：Annals of surgical oncology

authors： Ferrandina G,Gallotta V,Federico A,Fanfani F,Ercoli A,Chiantera V,Cosentino F,Turco LC,Legge F,Anchora LP,Bizzarri N,Moroni R,Macchia G,Valentini V,Scambia G

更新日期：2020-11-09 00:00:00

abstract：BACKGROUND:We performed a phase I study of a novel system of complete hepatic venous isolation and extracorporeal chemofiltration in patients with unresectable hepatocellular carcinoma (HCC) to determine (a) whether systemic exposure to doxorubicin could be limited after high-dose hepatic arterial infusion (HAI), and (...

journal_title：Annals of surgical oncology

authors： Curley SA,Newman RA,Dougherty TB,Fuhrman GM,Stone DL,Mikolajek JA,Guercio S,Guercio A,Carrasco CH,Kuo MT

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Robotic surgery is gaining momentum with advantages for minimally invasive management of pancreatic diseases. The objective of this meta-analysis is to compare the clinical and oncologic safety and efficacy of robotic versus open pancreatectomy. METHODS:A systematic review of the literature was performed to...

journal_title：Annals of surgical oncology

authors： Zhang J,Wu WM,You L,Zhao YP

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:The prognosis of lung cancer remains poor; only 20% of patients can undergo surgery. N2 non-small cell lung cancer (NSCLC) is a heterogeneous disease. We conducted a retrospective study to analyze the impact of N2 location on survival. METHODS:This study included 342 NSCLC with N2 involvement between 1988 a...

journal_title：Annals of surgical oncology

authors： Clément-Duchêne C,Luc A,Casse JM,Vignaud JM,Lacomme S,Anne V,Siat J,Ménard O,Martinet Y

更新日期：2018-05-01 00:00:00

abstract：INTRODUCTION:The National Comprehensive Cancer Network (NCCN) developed clinical practice guidelines for germline pathogenic variants in highly penetrant genes, such as TP53 and PTEN, and in moderately penetrant genes, such as CHEK2, ATM and PALB2. Whether the practice of radiographic surveillance of patients with path...

journal_title：Annals of surgical oncology

authors： Hudson L,Gower N,Lenarcic S,Trufan SJ,White RL Jr

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:The keystone flap is being promoted as an advance in oncological surgical reconstruction. Wound closure with this island flap involves two V-Y advancements toward the center and along the long axis of the island, at right angles to the line of maximum tension when the wound is closed. It is implied that the ...

journal_title：Annals of surgical oncology

authors： Douglas CD,Low NC,Seitz MJ

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:With cholangiocarcinoma, the only hope of a cure is resection. This study was undertaken to determine the impact of margin status, stage, tumor location, and adjuvant therapy on survival after resection of extrahepatic cholangiocarcinoma. METHODS:From 1985-2006, 91 patients underwent resections of cholangio...

journal_title：Annals of surgical oncology

authors： Hernandez J,Cowgill SM,Al-Saadi S,Villadolid D,Ross S,Kraemer E,Shapiro M,Mullinax J,Cooper J,Goldin S,Zervos E,Rosemurgy A

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Epithelial cells in the bone marrow of patients with gastric cancer suggest tumor dissemination; however, their prognostic implications are controversial. We prospectively evaluated the correlation of bone marrow findings, recurrence rate, and disease-free survival after long-term follow-up. METHODS:Bone ma...

journal_title：Annals of surgical oncology

authors： Gretschel S,Schick C,Schneider U,Estevez-Schwarz L,Bembenek A,Schlag PM

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Short-course radiotherapy with delayed surgery (SRT-delay) is still under clinical investigation for its efficacy in treating low rectal cancer (≤5 cm from the anal verge). This study was designed to assess the pattern of local recurrence and oncologic outcomes in T3 low rectal cancer treated with SRT-delay....

journal_title：Annals of surgical oncology

authors： Beppu N,Kimura F,Aihara T,Doi H,Tomita N,Yanagi H,Yamanaka N

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:The purpose of this study was to obtain a comprehensive understanding of the impact of postoperative tumor marker (TM) normalization on survival after pancreatectomy for pancreatic carcinoma. We propose the concept of surgical RECIST based on residual tumor and TM status. METHODS:A total of consecutive patient...

journal_title：Annals of surgical oncology

authors： Motoi F,Rikiyama T,Katayose Y,Egawa S,Unno M

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Incidence rates of hypoparathyroidism and vocal cord paralysis are high following central compartment reoperation, but few prospective studies have assessed morbidities and factors predictive of hypocalcemia after reoperation. We investigated recurrence patterns, morbidity, and factors predictive of postoper...

journal_title：Annals of surgical oncology

authors： Roh JL,Kim JM,Park CI

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:The interval between preoperative chemoradiotherapy and surgery reportedly affects perioperative outcomes and survival; however, the optimal interval in esophageal cancer patients remains uncertain. OBJECTIVE:Our aim was to determine whether a prolonged interval between preoperative neoadjuvant chemoradioth...

journal_title：Annals of surgical oncology

authors： Wakita A,Motoyama S,Sato Y,Nagaki Y,Fujita H,Terata K,Imai K,Minamiya Y

更新日期：2020-10-13 00:00:00

abstract：BACKGROUND:The Multicenter Selective Lymphadenectomy Trial-1 (MSLT-1) failed to demonstrate a survival advantage for sentinel lymph node biopsy (SNB) in melanoma. This may have been secondary to inadequate statistical power. This study was designed to determine the impact of SNB on melanoma-specific survival (MSS) in a...

journal_title：Annals of surgical oncology

authors： Kachare SD,Brinkley J,Wong JH,Vohra NA,Zervos EE,Fitzgerald TL

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:We postulated that the worse prognosis of melanoma with advancing age reflected more aggressive tumor biology and that in younger patients the prognosis would be more favorable. MATERIALS AND METHODS:The expanded AJCC melanoma staging database contained 11,088 patients with complete data for analysis, inclu...

journal_title：Annals of surgical oncology

authors： Balch CM,Soong SJ,Gershenwald JE,Thompson JF,Coit DG,Atkins MB,Ding S,Cochran AJ,Eggermont AM,Flaherty KT,Gimotty PA,Johnson TM,Kirkwood JM,Leong SP,McMasters KM,Mihm MC Jr,Morton DL,Ross MI,Sondak VK

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:There is increasing evidence that tumor hypoxia plays a significant role in the chemoresistance of melanoma, but to our knowledge, real-time tumor oxygenation during isolated limb infusion (ILI) has not been studied. We sought to demonstrate the feasibility of measuring real-time alterations in tissue oxygen...

journal_title：Annals of surgical oncology

authors： Speicher PJ,Beasley GM,Jiang B,Lidsky ME,Palmer GM,Scarbrough PM,Mosca PJ,Dewhirst MW,Tyler DS

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:The performance of a mastectomy for the treatment or prophylaxis of breast cancer may have long-term implications for both physical and mental well-being in women. The development of breast numbness and phantom breast sensations following mastectomy is well-known; however, relatively little is known about phy...

journal_title：Annals of surgical oncology

authors： McCarthy CM,Mehrara BJ,Long T,Garcia P,Kropf N,Klassen AF,Cano SJ,Li Y,Hurley K,Scott A,Disa JJ,Cordeiro PG,Pusic AL

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:Our study aims to determine whether patients with lobular-type breast cancer have significantly improved rates of breast conservation (BCT) after neoadjuvant chemotherapy (nCT). METHODS:Patients who received nCT and surgery within three prospective trials between 1995 and 2007 at the Medical University of...

journal_title：Annals of surgical oncology

authors： Fitzal F,Mittlboeck M,Steger G,Bartsch R,Rudas M,Dubsky P,Riedl O,Jakesz R,Gnant M

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Our objective was to correlate the extent of margin positivity and the findings on re-excision specimens of infiltrating mammary carcinoma. METHODS:We selected 50 consecutive cases of infiltrating mammary carcinoma, including both infiltrating ductal carcinoma and infiltrating lobular carcinoma, with positi...

journal_title：Annals of surgical oncology

authors： Darvishian F,Hajdu SI,DeRisi DC

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Consensus guidelines recommend prolonged thromboprophylaxis for up to 4 weeks after major abdominopelvic cancer operations. Several factors impede widespread adoption of these guidelines. These include lack of awareness, cost, increased bleeding complications, increased incidence of heparin-induced thrombocy...

journal_title：Annals of surgical oncology

authors： Bradley CT,Brasel KJ,Miller JJ,Pappas SG

更新日期：2010-01-01 00:00:00