Should adjuvant therapy remain the standard of care for patients with resected adenocarcinoma of the pancreas?

abstract：BACKGROUND:The role of surgical resection in patients with large or multinodular hepatocellular carcinoma (HCC) remains unclear. This study evaluated the long-term outcome of patients with hepatic resection for large (>5 cm in diameter) or multinodular (more than three nodules) HCC by using a multi-institutional databa...

journal_title：Annals of surgical oncology

authors： Ng KK,Vauthey JN,Pawlik TM,Lauwers GY,Regimbeau JM,Belghiti J,Ikai I,Yamaoka Y,Curley SA,Nagorney DM,Ng IO,Fan ST,Poon RT,International Cooperative Study Group on Hepatocellular Carcinoma.

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Percutaneous biliary drainage (PBD) is used to relieve malignant bile duct obstruction (MBO) when endoscopic drainage is not feasible. Little is known about the effects of PBD on the quality of life (QoL) in patients with MBO. The aim of this study was to evaluate changes in QoL and pruritus after PBD and to...

journal_title：Annals of surgical oncology

authors： Robson PC,Heffernan N,Gonen M,Thornton R,Brody LA,Holmes R,Brown KT,Covey AM,Fleischer D,Getrajdman GI,Jarnagin W,Sofocleous C,Blumgart L,D'Angelica M

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Resectability rates for extrahepatic cholangiocarcinoma have increased over time, but long-term survival after resection alone with curative intent remains poor. Recent series suggest improved survival with adjuvant therapy. Patient subsets benefiting most from adjuvant therapy have not been clearly defined....

journal_title：Annals of surgical oncology

authors： Ecker BL,Vining CC,Roses RE,Maggino L,Lee MK,Drebin JA,Fraker DL,Vollmer CM Jr,Datta J

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Postoperative chemoradiation and perioperative chemotherapy using epirubicin/cisplatin/5-fluorouracil (ECF) represent two standards of care for resectable gastric cancer. In the TOPGEAR (Trial Of Preoperative therapy for Gastric and Esophagogastric junction AdenocaRcinoma) trial, we hypothesized that adding ...

journal_title：Annals of surgical oncology

authors： Leong T,Smithers BM,Haustermans K,Michael M,Gebski V,Miller D,Zalcberg J,Boussioutas A,Findlay M,O'Connell RL,Verghis J,Willis D,Kron T,Crain M,Murray WK,Lordick F,Swallow C,Darling G,Simes J,Wong R

更新日期：2017-08-01 00:00:00

abstract：:In the original article Massimo Milione's last name was spelled incorrectly. It is correct as reflected here. The original article has also been updated. ...

journal_title：Annals of surgical oncology

authors： Guaglio M,Sinukumar S,Kusamura S,Milione M,Pietrantonio F,Battaglia L,Guadagni S,Baratti D,Deraco M

更新日期：2018-12-01 00:00:00

abstract：INTRODUCTION:The change in TNM classification of malignant pleural mesothelioma (MPM) between the seventh and eighth edition classifications has resulted in the downstaging of many advanced-stage patients into pathological stage IB. Many mesotheliomas without lymph node metastasis have been classified as stage IB in th...

journal_title：Annals of surgical oncology

authors： Takuwa T,Hashimoto M,Kuroda A,Nakamura A,Nakamichi T,Fukuda A,Matsumoto S,Kondo N,Hasegawa S

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:Atypical protein kinase C iota (aPKC-iota) and its associated intracellular molecules, E-cadherin and beta-catenin, are important for cell polarization in tumorigenesis and progression. Expression of aPKC-iota, P-aPKC-iota (activated aPKC-iota), E-cadherin, and beta-catenin in hepatocellular carcinoma (HCC) ...

journal_title：Annals of surgical oncology

authors： Du GS,Wang JM,Lu JX,Li Q,Ma CQ,Du JT,Zou SQ

更新日期：2009-06-01 00:00:00

abstract：:Tumors treated with preoperative chemotherapy or radiation often demonstrate evidence of response in the resection specimen. Pathologic response is often interpreted as a surrogate for recurrence or survival outcomes. With a valid surrogate for long-term outcomes, investigators can explore treatment strategies with im...

journal_title：Annals of surgical oncology

authors： Mansour JC,Schwarz RE

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Low-dose rate brachytherapy is a well-established adjuvant treatment for soft tissue sarcomas (STS). The experience with high-dose rate brachytherapy (HDR BT) in this indication is limited. The purpose of our study was to evaluate the viability of perioperative hyperfractionated HDR BT for STS. METHODS:Fort...

journal_title：Annals of surgical oncology

authors： Petera J,Soumarová R,Růzicková J,Neumanová R,Dusek L,Sirák I,Macingová Z,Paluska P,Kasaová L,Hodek M,Vosmik M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinase 7 (MMP-7) is involved in invasion, metastasis, growth, and angiogenesis. The aim of this study is to assess the prognostic role of serum MMP-7 in curatively resected colorectal cancer (CRC). MATERIALS AND METHODS:Patients undergoing resection for CRC (n = 175) were recruited from Ju...

journal_title：Annals of surgical oncology

authors： Martínez-Fernandez A,García-Albeniz X,Pineda E,Visa L,Gallego R,Codony-Servat J,Augé JM,Longarón R,Gascón P,Lacy A,Castells A,Maurel J

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Nutritional derangements are common hallmarks of pancreatic cancer (PC). Their early detection and management are usually overlooked in routine practice. This study aimed to explore preoperative nutritional status and its prognostic value in patients undergoing surgery for PC. METHODS:Data from 73 patients ...

journal_title：Annals of surgical oncology

authors： Trestini I,Paiella S,Sandini M,Sperduti I,Elio G,Pollini T,Melisi D,Auriemma A,Soldà C,Bonaiuto C,Tregnago D,Avancini A,Secchettin E,Bonamini D,Lanza M,Pilotto S,Malleo G,Salvia R,Bovo C,Gianotti L,Bassi C,Milel

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:During the breast lumpectomy procedure, surgeons traditionally elect to use either a superficial or full-thickness closure when sealing the wound depending on surgeon preference as well as desired outcomes. The purpose of this study was to examine dosimetric endpoints in patients with superficial versus full...

journal_title：Annals of surgical oncology

authors： Shaikh T,Narra V,Goyal S,Ahlawat S,Kirstein L,Kearney T,Haffty BG,Khan AJ

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:The prospective Neoadjuvant Breast Symphony Trial (NBRST) study found that MammaPrint/BluePrint functional molecular subtype is superior to conventional immunohistochemistry/fluorescence in situ hybridization subtyping for predicting pathologic complete response (pCR) to neoadjuvant chemotherapy. The purpose...

journal_title：Annals of surgical oncology

authors： Baron P,Beitsch P,Boselli D,Symanowski J,Pellicane JV,Beatty J,Richards P,Mislowsky A,Nash C,Lee LA,Murray M,de Snoo FA,Stork-Sloots L,Gittleman M,Akbari S,Whitworth P

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:There are many theoretical advantages that a minimally invasive approach to the pancreaticoduodenectomy might offer patients with benign and malignant disease of the head of the pancreas over traditional open techniques, including improved recovery time, decreased hospital stay, and earlier initiation of and...

journal_title：Annals of surgical oncology

authors： Zeh HJ,Zureikat AH,Secrest A,Dauoudi M,Bartlett D,Moser AJ

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Extensive lymph node dissection (LND) is beneficial in primarily resected esophageal cancer patients. Such benefit was believed to be seen in neoadjuvant chemoradiotherapy (CRT)-treated patients, but evidence was inconsistent. We hypothesized that CRT might offset the benefit of LND in certain subgroup of pa...

journal_title：Annals of surgical oncology

authors： Chao YK,Liu HP,Hsieh MJ,Wu YC,Liu YH,Yeh CH,Chang HK,Tseng CK

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Fine-needle aspiration biopsy (FNAB) of the thyroid categorized as atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) is a newly defined category according to the recent Bethesda guidelines. We sought to assess the characteristics and treatment of patients with an A...

journal_title：Annals of surgical oncology

authors： Nagarkatti SS,Faquin WC,Lubitz CC,Garcia DM,Barbesino G,Ross DS,Hodin RA,Daniels GH,Parangi S

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Surgical resection is the most important therapeutic intervention for eligible patients with pancreatic cancer; however, a majority of patients never receive surgery for a variety of reasons, including patient refusal. Utilizing the National Cancer Database, we investigated the associated sociodemographic an...

journal_title：Annals of surgical oncology

authors： Coffman A,Torgeson A,Lloyd S

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Experimental studies have revealed that D2-40 is useful in identifying the presence of lymphatic invasion in various malignant neoplasms, but the clinical significance remains unclear. The purpose of this study is to assess the clinical significance of D2-40 status in completely resected non-small cell lung ...

journal_title：Annals of surgical oncology

authors： Iwakiri S,Nagai S,Katakura H,Takenaka K,Date H,Wada H,Tanaka F

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Radiofrequency ablation (RFA) for the treatment of hepatic tumors has been increasingly used across the United States. Whether treatment-related morbidity has remained low with broader adoption is unclear. We conducted this study to describe in-hospital morbidity associated with RFA for hepatic tumors and to...

journal_title：Annals of surgical oncology

authors： Fox JP,Gustafson J,Desai MM,Hellan M,Thambi-Pillai T,Ouellette J

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Adenoviral gene therapy is a promising new approach for the treatment of neoplastic diseases. To design rational clinical trials and distinguish the effects of therapeutic transgene expression from those caused by viral infection alone, the immune response to the vector must be understood. In these experimen...

journal_title：Annals of surgical oncology

authors： DeMatteo RP,Yeh H,Friscia M,Caparrelli D,Burke C,Desai N,Chu G,Markmann JF,Raper SE,Barker CF

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Management of mammographically detected ductal carcinoma in situ (DCIS) at a single institution was reviewed to determine long-term clinical outcomes after treatment with breast-conserving therapy (BCT). METHODS:Data from all patient-cases with DCIS who received BCT between 1980 and 1993 were reviewed. Pati...

journal_title：Annals of surgical oncology

authors： Wilkinson JB,Vicini FA,Shah C,Shaitelman S,Jawad MS,Ye H,Kestin LL,Goldstein NS,Martinez AA,Benitez P,Chen PY

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Hereditary diffuse gastric cancer (HDGC) is an autosomal dominant cancer syndrome. Up to 30% of families with HDGC have mutations in the E-cadherin gene, CDH1. The role of prophylactic versus therapeutic gastrectomy for HDGC was studied prospectively. METHODS:Eighteen consecutive patients with CDH1 mutation...

journal_title：Annals of surgical oncology

authors： Chen Y,Kingham K,Ford JM,Rosing J,Van Dam J,Jeffrey RB,Longacre TA,Chun N,Kurian A,Norton JA

更新日期：2011-09-01 00:00:00

abstract：: ...

journal_title：Annals of surgical oncology

authors： Blok RD,Tanis PJ

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:In primary esophageal cancer, studies have frequently focused on surgical patients in an effort to link outcome to hospital- or surgeon-related experience, with operative mortality used as the main outcome measure. Many studies have found an inverse relationship between operative mortality and hospital volum...

journal_title：Annals of surgical oncology

authors： Verhoef C,van de Weyer R,Schaapveld M,Bastiaannet E,Plukker JT

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:This anatomic study details the lymphatic drainage of the upper extremity (UE) and breast, as well as its course in the axilla and its relation to axillary reverse mapping. Two aspects important for breast cancer surgery were followed: connection between the lymphatics of the UE and breast, and the possible ...

journal_title：Annals of surgical oncology

authors： Pavlista D,Eliska O

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:As increased focus is placed on quality of care in surgery, readmission is an increasingly important metric by which hospital and surgeon quality is measured. For complex pancreatic surgery, we hypothesized that increased pancreaticoduodenectomy (PD) volume may mitigate readmission rates. METHODS:The Univer...

journal_title：Annals of surgical oncology

authors： Sutton JM,Wilson GC,Wima K,Hoehn RS,Cutler Quillin R 3rd,Hanseman DJ,Paquette IM,Sussman JJ,Ahmad SA,Shah SA,Abbott DE

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Randomized clinical trials (RCTs) can provide a high level of evidence for medical decision making, but it is unclear if the results apply to patients treated outside such trials. OBJECTIVE:The aim of this study was to retrospectively compare outcomes of patients with esophageal cancer treated within and ou...

journal_title：Annals of surgical oncology

authors： Toxopeus E,van der Schaaf M,van Lanschot J,Lagergren J,Lagergren P,van der Gaast A,Wijnhoven B

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The traditional Billroth II and Roux-en-Y anastomosis after laparoscopic distal gastrectomy for gastric cancer are associated with bile reflux gastritis and roux stasis syndrome, respectively. The uncut Roux-en-Y gastrojejunostomy can decrease the incidence of these complications by blocking the entry of bil...

journal_title：Annals of surgical oncology

authors： Wang J,Wang Q,Dong J,Yang K,Ji S,Fan Y,Wang C,Ma Q,Wei Q,Ji G

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Local treatment of colorectal cancer, including endoscopic removal of colonic polyps and transanal resection of rectal tumors, has become widely accepted. However, risk factors predicting the presence of lymph node metastasis have not been fully investigated. To determine the criteria for local excision of c...

journal_title：Annals of surgical oncology

authors： Adachi Y,Yasuda K,Kakisako K,Sato K,Shiraishi N,Kitano S

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Carcinomatosis of colorectal origin is increasingly treated by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CS-HIPEC). This procedure commonly involves multivisceral resection (MVR) with potentially high morbidity. We analyzed the effect of MVR on the outcome after CS-HIPEC. METHODS:...

journal_title：Annals of surgical oncology

authors： Franko J,Gusani NJ,Holtzman MP,Ahrendt SA,Jones HL,Zeh HJ 3rd,Bartlett DL

更新日期：2008-11-01 00:00:00