Cellular immunity delimits adenoviral gene therapy strategies for the treatment of neoplastic diseases.

abstract：BACKGROUND:Remote home monitoring might fill the perceived surveillance gap after hospital discharge. However, it is unclear whether older oncologic patients will be able to use the required new digital technologies. The study aimed to assess the feasibility of postoperative remote home monitoring for this population. ...

journal_title：Annals of surgical oncology

authors： Jonker LT,Plas M,de Bock GH,Buskens E,van Leeuwen BL,Lahr MMH

更新日期：2021-01-01 00:00:00

abstract：:Investigators at many cancer centers have verified that the sentinel node (SN) is the first lymph node to receive lymphatic drainage from a primary breast cancer and therefore the node most likely to contain metastatic tumor cells. When sentinel lymph node dissection (SLND) is undertaken by an experienced multidiscipl...

journal_title：Annals of surgical oncology

authors： Giuliano AE

更新日期：2001-10-01 00:00:00

abstract：:Cancer Prevention is an emerging field, capturing the old traditional concept of anticipating the development of a major disease and preventing its full impact by early detection, treatment, or aborting the tumorigenic process by a "molecular vaccine" and alleviating the full impact of the disease. Surgeons are import...

journal_title：Annals of surgical oncology

authors： Chu DZ,Gibson G,David D,Yen Y

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Resection of melanoma metastatic to the liver remains controversial. We evaluated the efficacy of hepatic resection in patients with metastatic ocular and cutaneous melanoma and assessed factors that could affect survival after resection. METHODS:Forty patients with hepatic melanoma metastasis underwent res...

journal_title：Annals of surgical oncology

authors： Pawlik TM,Zorzi D,Abdalla EK,Clary BM,Gershenwald JE,Ross MI,Aloia TA,Curley SA,Camacho LH,Capussotti L,Elias D,Vauthey JN

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:The added value of surgery in breast cancer patients with pathological complete response (pCR) after neoadjuvant systemic therapy (NST) is uncertain. The accuracy of imaging identifying pCR for omission of surgery, however, is insufficient. We investigated the accuracy of ultrasound-guided biopsies identifyi...

journal_title：Annals of surgical oncology

authors： van Loevezijn AA,van der Noordaa MEM,van Werkhoven ED,Loo CE,Winter-Warnars GAO,Wiersma T,van de Vijver KK,Groen EJ,Blanken-Peeters CFJM,Zonneveld BJGL,Sonke GS,van Duijnhoven FH,Vrancken Peeters MTFD

更新日期：2020-12-02 00:00:00

abstract：BACKGROUND:The National Comprehensive Cancer Network (NCCN) recommends that at least 15 lymph nodes (LNs) be removed during radical gastrectomy. This study aims to investigate the optimal number of LNs resected for radical gastrectomy. PATIENTS AND METHODS:From September 2008 to March 2015, a total of 1990 gastric can...

journal_title：Annals of surgical oncology

authors： Zheng G,Feng F,Guo M,Xu G,Liu S,Liu Z,Sun L,Hong L,Yang J,Lian X,Fan D,Zhang H

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:The maximum size of adrenal tumors that should be removed with a laparoscopic approach is controversial. It has been suggested that laparoscopic adrenalectomy is appropriate only for adrenal tumors < 6 cm in size. We report our experience with laparoscopic adrenalectomy in patients with adrenal tumors of > o...

journal_title：Annals of surgical oncology

authors： MacGillivray DC,Whalen GF,Malchoff CD,Oppenheim DS,Shichman SJ

更新日期：2002-06-01 00:00:00

abstract：:Adenocarcinoma of the pancreas continues to be a formidable disease. In the United States, patients who have had resected disease are generally offered adjuvant chemoradiation. The current National Comprehensive Cancer Network practice guidelines uniformly support this practice. We reviewed seven selected series to ev...

journal_title：Annals of surgical oncology

authors： Chu QD,Khushalani N,Javle MM,Douglass HO Jr,Gibbs JF

更新日期：2003-06-01 00:00:00

abstract：INTRODUCTION:Plantar melanomas are a challenge to reconstruct after wide excision. Non-glaborous skin grafts have resulted in tissue loss, hyperkeratosis, marginal scarring, and poor functional outcomes, leading many to utilize various flaps for reconstruction that are technically demanding and associated with increase...

journal_title：Annals of surgical oncology

authors： Maker AV,Iteld L

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Growing evidence suggests that the tumor immune microenvironment influences breast cancer development and prognosis. Density of tumor-infiltrating lymphocytes (TILs) within invasive breast cancer is correlated with response to therapy, especially in triple-negative disease. The clinical relevance and outcome...

journal_title：Annals of surgical oncology

authors： Darvishian F,Ozerdem U,Adams S,Chun J,Pirraglia E,Kaplowitz E,Guth A,Axelrod D,Shapiro R,Price A,Troxel A,Schnabel F,Roses D

更新日期：2019-10-01 00:00:00

abstract：: ...

journal_title：Annals of surgical oncology

authors： Xie X

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:Early-stage breast cancer patients with minimal axillary disease identified by sentinel lymph node dissection (SLND) have low regional recurrence rates when treated with breast-conserving surgery and radiation therapy (XRT) and many avoid a completion axillary lymph node dissection (CLND). As the incidence of t...

journal_title：Annals of surgical oncology

authors： FitzSullivan E,Bassett RL,Kuerer HM,Mittendorf EA,Yi M,Hunt KK,Babiera GV,Caudle AS,Black DM,Bedrosian I,Reyna C,Teshome M,Meric-Bernstam F,Hwang R

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:This study compared two homogeneous groups of patients submitted to either surgical resection (HR) or laparoscopic radiofrequency ablation (LRFA) for the treatment of hepatocellular carcinoma (HCC). When compatible with the liver functional reserve, HR remains the treatment of choice for HCC, while LRFA seem...

journal_title：Annals of surgical oncology

authors： Santambrogio R,Opocher E,Zuin M,Selmi C,Bertolini E,Costa M,Conti M,Montorsi M

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Cytoreductive therapy for metastatic carcinoid provides symptomatic relief and improvement in overall survival. We evaluated whether CgA and 5HIAA could predict symptomatic relief and control of disease progression after cytoreductive surgery. METHODS:We retrospectively reviewed 70 patients who underwent cy...

journal_title：Annals of surgical oncology

authors： Jensen EH,Kvols L,McLoughlin JM,Lewis JM,Alvarado MD,Yeatman T,Malafa M,Shibata D

更新日期：2007-02-01 00:00:00

abstract：PURPOSE:Intraoperative margin assessment can reduce positive margins in patients undergoing breast-conserving surgery. However, reports on intraoperative margin assessment have described only the use of either imprint cytology or frozen section. This study was designed to elucidate the effect of intraoperative margin a...

journal_title：Annals of surgical oncology

authors： Tamanuki T,Namura M,Aoyagi T,Shimizu S,Suwa T,Matsuzaki H

更新日期：2020-08-19 00:00:00

abstract：BACKGROUND:Biomarkers for accurate diagnosis of early hepatocellular carcinoma (HCC) are limited in number and clinical validation. We applied SELDI-TOF-MS ProteinChip technology to identify serum profile for distinguishing HCC and liver cirrhosis (LC) and to compare the accuracy of SELDI-TOF-MS profile and alpha-fetop...

journal_title：Annals of surgical oncology

authors： Chen L,Ho DW,Lee NP,Sun S,Lam B,Wong KF,Yi X,Lau GK,Ng EW,Poon TC,Lai PB,Cai Z,Peng J,Leng X,Poon RT,Luk JM

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Hospitalization is associated with negative clinical effects that last beyond discharge. This study aimed to determine whether hospitalization in the year before major oncologic surgery is associated with adverse outcomes. METHODS:Patients 18 years of age or older with stomach, pancreas, colon, or rectal ca...

journal_title：Annals of surgical oncology

authors： Sharoky CE,Collier KT,Wirtalla CJ,Sinnamon AJ,Neuwirth MG,Kuo LE,Roses RE,Fraker DL,Karakousis GC,Kelz RR

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Epigenetic silencing of tumor-related genes by CpG island methylation is an important mechanism for the development of many tumors, including gastric carcinoma. Deregulation of transcription factor 4 (TCF4) by promoter methylation was recently shown to play a key role in gastric carcinogenesis. METHODS:The ...

journal_title：Annals of surgical oncology

authors： Joo JK,Kim SH,Kim HG,Kim DY,Ryu SY,Lee KH,Lee JH

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Since its introduction, the sentinel lymph node biopsy (SLNB) has become the standard staging procedure in clinical node-negative melanoma patients. A negative SLNB, however, does not guarantee a recurrence-free survival. Insight into metastatic patterns and risk factors for recurrence in SLNB negative melan...

journal_title：Annals of surgical oncology

authors： Faut M,Wevers KP,van Ginkel RJ,Diercks GF,Hoekstra HJ,Kruijff S,Been LB,van Leeuwen BL

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The standard treatment for patients 75 years of age or younger with cStage 2 or 3 esophageal cancer is preoperative chemotherapy followed by esophagectomy. The optimal treatment for elderly patients, especially those considered vulnerable, remains unclear. METHODS:This study retrospectively reviewed the dat...

journal_title：Annals of surgical oncology

authors： Booka E,Haneda R,Ishii K,Tsushima T,Yasui H,Tsubosa Y

更新日期：2020-09-02 00:00:00

abstract：BACKGROUND:Transarterial chemoembolization (TACE) is often utilized for patients with inoperable neuroendocrine carcinoma liver metastases. Often, metastatic disease is not limited to the liver. The impact of extrahepatic disease (EHD) on outcomes and response after TACE has not been described. METHODS:We reviewed 192...

journal_title：Annals of surgical oncology

authors： Arrese D,McNally ME,Chokshi R,Feria-Arias E,Schmidt C,Klemanski D,Gregory G,Khabiri H,Shah M,Bloomston M

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Although the sentinel lymph node (SLN) hypothesis has been applied to many tissues and organs, liver has remained unstudied. Currently, it is unclear whether hepatic SLNs even exist. If so, they could alter the management of intrahepatic cholangiocarcinoma and other hepatic malignancies by minimizing the ext...

journal_title：Annals of surgical oncology

authors： Wada H,Hyun H,Vargas C,Genega EM,Gravier J,Gioux S,Frangioni JV,Choi HS

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Postoperative complications have been recognized to have an adverse prognostic impact in various types of cancer. However, in a recent study, it has been reported that postoperative complications of total gastrectomy with splenectomy have little impact on the long-term outcomes of patients with gastric cance...

journal_title：Annals of surgical oncology

authors： Maruyama S,Kawaguchi Y,Akaike H,Shoda K,Saito R,Shimizu H,Furuya S,Hosomura N,Amemiya H,Kawaida H,Sudo M,Inoue S,Kono H,Ichikawa D

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:To evaluate the effect and safety of laparoscopy-assisted renal autotransplantation treatment for primary ureteral cancer (PUC). METHODS:Medical records of patients undergoing hand-assisted retroperitoneoscopic nephroureterectomy–extracorporeal total ureterectomy–renal autotransplantation–pyelocystostomy (L...

journal_title：Annals of surgical oncology

authors： Cheng YT,Flechner SM,Chiang PH

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Early diagnosis of superior mesenteric artery (SMA) involvement is vital for patients with a borderline resectable cancer of the pancreatic head to achieve an R0 resection. We aimed to detect the effect of the inferior infracolic 'superior mesenteric artery first' approach with a no-touch isolation surgical ...

journal_title：Annals of surgical oncology

authors： Zhu J,Han D,Li X,Pan F,Ma J,Kou J,Fan H,Lang R,He Q

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:The prognosis of humeral sarcomas has improved greatly in the past 20 years. As a result, the challenges for orthopedic oncologists include long-term handicap and local morbidity. METHODS:Shoulder reconstruction after the resection of sarcomas with the proximal humerus was evaluated for 55 patients from 199...

journal_title：Annals of surgical oncology

authors： Wang J,Shen J,Dickinson IC

更新日期：2011-07-01 00:00:00

abstract：:There is increasing evidence regarding extracapsular lymph node involvement (LNI) as a prognostic factor for recurrence and poor prognosis in gastrointestinal malignancies. The aim of this study was to assess the prevalence and prognostic impact of LNI in patients with resected esophageal cancer, comparing adenocarcin...

journal_title：Annals of surgical oncology

authors： Metzger R,Drebber U,Baldus SE,Mönig SP,Hölscher AH,Bollschweiler E

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Liver kinase B1 (LKB1) loss by gene mutation, loss of heterozygosity, and promoter methylation rarely occurs in colorectal cancer. We wondered whether LKB1 loss could be deregulated at the transcriptional level to promote tumor progression and poor outcome in colorectal cancer. METHODS:Mechanistic studies w...

journal_title：Annals of surgical oncology

authors： He TY,Tsai LH,Huang CC,Chou MC,Lee H

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:The EUropean REgistration of Cancer CAre (EURECCA) consortium aims to investigate differences in treatment and to improve cancer care through Europe. The purpose of this study was to compare neo- and adjuvant chemotherapy (ACT) and outcome after tumor resection for pancreatic adenocarcinoma stage I and II in...

journal_title：Annals of surgical oncology

authors： Groen JV,Sibinga Mulder BG,van Eycken E,Valerianova Z,Borras JM,van der Geest LGM,Capretti G,Schlesinger-Raab A,Primic-Zakelj M,Ryzhov A,van de Velde CJH,Bonsing BA,Bastiaannet E,Mieog JSD

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:It is still controversial whether tumor size (Ts) should be considered an important indicator for evaluation the prognosis of gastric cancer (GC). The purpose of this study was to elucidate the prognostic prediction superiority of Ts in the large-scale cohort of GC patients. METHODS:Data from 1,521 patients...

journal_title：Annals of surgical oncology

authors： Deng J,Zhang R,Pan Y,Ding X,Cai M,Liu Y,Liu H,Bao T,Jiao X,Hao X,Liang H

更新日期：2015-02-01 00:00:00