The surgeon's role in cancer prevention. The model in colorectal carcinoma.

Abstract:

:Cancer Prevention is an emerging field, capturing the old traditional concept of anticipating the development of a major disease and preventing its full impact by early detection, treatment, or aborting the tumorigenic process by a "molecular vaccine" and alleviating the full impact of the disease. Surgeons are important clinician scientists who can carry this discipline forward and develop its full potential in the clinics and in the community. Advances in molecular biology, genetics, and other technologies have permitted seminal understanding of the carcinogenic pathways and identification of targets and intermediate end points in neoplasia. In this review, we will see that we have the means of preventing significant numbers of colorectal carcinomas (CRC).

journal_name

Ann Surg Oncol

authors

Chu DZ,Gibson G,David D,Yen Y

doi

10.1245/s10434-007-9485-6

subject

Has Abstract

pub_date

2007-11-01 00:00:00

pages

3054-69

issue

11

eissn

1068-9265

issn

1534-4681

journal_volume

14

pub_type

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