Better survival in patients with esophageal cancer after surgical treatment in university hospitals: a plea for performance by surgical oncologists.

abstract：OBJECTIVE:The aim of this study was to investigate the correlation between clinical complete response (cCR) and pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (CRT) for esophageal squamous cell cancer (ESCC). METHODS:Between May 2001 and April 2013, a total of 158 patients with thoracic ESCC tr...

journal_title：Annals of surgical oncology

authors： Liu SL,Xi M,Yang H,Yang YD,Wu YJ,Zhao L,Zhang P,Luo LL,Liu MZ

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Metastatic breast cancer is an aggressive disease associated with recurrence and decreased survival. To improve outcomes and develop more effective treatment strategies for patients with breast cancer, it is important to understand the molecular mechanisms underlying metastasis. METHODS:We used allelic imba...

journal_title：Annals of surgical oncology

authors： Becker TE,Ellsworth RE,Deyarmin B,Patney HL,Jordan RM,Hooke JA,Shriver CD,Ellsworth DL

更新日期：2008-04-01 00:00:00

abstract：INTRODUCTION:Plantar melanomas are a challenge to reconstruct after wide excision. Non-glaborous skin grafts have resulted in tissue loss, hyperkeratosis, marginal scarring, and poor functional outcomes, leading many to utilize various flaps for reconstruction that are technically demanding and associated with increase...

journal_title：Annals of surgical oncology

authors： Maker AV,Iteld L

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:The importance of absent neoplastic epithelium in specimens from cytoreductive surgery (CRS) is unknown. This study aimed to investigate the prevalence and prognostic value of histopathology without neoplastic epithelium in patients treated with CRS and hyperthermic intraperitoneal chemotherapy (HIPEC). MET...

journal_title：Annals of surgical oncology

authors： Enblad M,Birgisson H,Wanders A,Sköldberg F,Ghanipour L,Graf W

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Brain metastases account for 20-54% of reported deaths from melanoma. Duration and quality of survival depend on the extent of metastatic disease and response to treatment. Treatment goals are palliation of symptoms and prolongation of life. No studies have directly compared surgery alone and surgery with ad...

journal_title：Annals of surgical oncology

authors： Skibber JM,Soong SJ,Austin L,Balch CM,Sawaya RE

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Adenoviral gene therapy is a promising new approach for the treatment of neoplastic diseases. To design rational clinical trials and distinguish the effects of therapeutic transgene expression from those caused by viral infection alone, the immune response to the vector must be understood. In these experimen...

journal_title：Annals of surgical oncology

authors： DeMatteo RP,Yeh H,Friscia M,Caparrelli D,Burke C,Desai N,Chu G,Markmann JF,Raper SE,Barker CF

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Data from randomized controlled trials support use of a diverting stoma in rectal cancer patients with low anastomoses, but there is little data on how this impacts patient quality of life (QOL). This study prospectively evaluates QOL in stage I-III rectal cancer patients undergoing sphincter-preserving surg...

journal_title：Annals of surgical oncology

authors： Neuman HB,Patil S,Fuzesi S,Wong WD,Weiser MR,Guillem JG,Paty PB,Nash GM,Temple LK

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Detection of cancer micrometastases is required for improvement of cancer therapy. The aim of this study was to establish a rapid and practical genetic assay to detect micrometastasis in gastric cancer and to assess its clinical significance with respect to prognosis. METHODS:A novel RNA amplification syste...

journal_title：Annals of surgical oncology

authors： Ishii T,Fujiwara Y,Ohnaka S,Hayashi T,Taniguchi H,Takiguchi S,Yasuda T,Yano M,Monden M

更新日期：2004-08-01 00:00:00

abstract：METHODS:This study evaluated the effectiveness and morbidity associated with 116 peritoneovenous shunts inserted into 89 patients for symptomatic malignant ascites between 1981 and 1991. All patients had previously failed standard medical therapy of salt and fluid restriction, diuretics, and intermittent peritoneal asp...

journal_title：Annals of surgical oncology

authors： Schumacher DL,Saclarides TJ,Staren ED

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Bone marrow (BM) biopsy has been suggested as an independent prognostic factor in patients with breast cancer. METHODS:Patients operated for breast cancer from June 2000 to April 2008 were enrolled in this protocol after signing an informed consent. After primary surgery, BM aspirate from the iliac crest wa...

journal_title：Annals of surgical oncology

authors： Fortunato L,Mascaro A,Baldi A,Farina M,Cortese G,Ventrone MA,Amini M,Vitelli C

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Although the American Joint Committee on Cancer (AJCC) classification is the most accepted lymph node (LN) staging system for gallbladder adenocarcinoma (GBA), other LN prognostic schemes have been proposed. This study sought to define the performance of the AJCC LN staging system relative to the number of m...

journal_title：Annals of surgical oncology

authors： Amini N,Kim Y,Wilson A,Margonis GA,Ethun CG,Poultsides G,Tran T,Idrees K,Isom CA,Fields RC,Krasnick B,Weber SM,Salem A,Martin RC,Scoggins C,Shen P,Mogal HD,Schmidt C,Beal E,Hatzaras I,Shenoy R,Maithel SK,Pawli

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Chemotherapy is increasingly used before hepatic resection, with controversial impact regarding liver function. This study aimed to assess the capacity of 99mTc-labelled-mebrofenin SPECT-hepatobiliary scintigraphy (HBS) to predict liver dysfunction due to chemotherapy and/or chemotherapeutic-associated liver...

journal_title：Annals of surgical oncology

authors： Truant S,Baillet C,Gnemmi V,Fulbert M,Turpin A,Dardenne S,Leteurtre E,El Amrani M,Dharancy S,Dubuquoy L,Huglo D,Chesné C,Pruvot FR

更新日期：2020-08-24 00:00:00

abstract：BACKGROUND:The risk of colorectal cancer (CRC) in chronic kidney disease (CKD) patients relative to the general population is unknown. The aim of this population-based study was to investigate the risk of CRC in patients with CKD. METHODS:The study cohort included patients aged ≥18 years diagnosed with CKD between 200...

journal_title：Annals of surgical oncology

authors： Wu MY,Chang TC,Chao TY,Huang MT,Lin HW

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Isolated limb perfusion (ILP) results in complete response (CR) rates of 60% to 90% in patients with regionally advanced melanoma. Survival after a CR may be influenced by various factors, particularly out-of-field disease in iliac lymph nodes (ILN) identified during lower-extremity ILP. We examined clinical...

journal_title：Annals of surgical oncology

authors： Zogakis TG,Bartlett DL,Libutti SK,Liewehr DJ,Steinberg SM,Fraker DL,Alexander HR

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemoperfusion (HIPEC) is routinely used to treat certain peritoneal carcinomatoses (PC), but it can be associated with relatively high complication rates, prolonged hospital length of stay, and potential mortality. Our objective was to determine ...

journal_title：Annals of surgical oncology

authors： Polanco PM,Ding Y,Knox JM,Ramalingam L,Jones H,Hogg ME,Zureikat AH,Holtzman MP,Pingpank J,Ahrendt S,Zeh HJ,Bartlett DL,Choudry HA

更新日期：2015-05-01 00:00:00

abstract：:Integrins play an important role in various lymphocyte functions. In this study, we isolated lamina propria lymphocytes (LPL) and tumor-infiltrating lymphocytes (TIL) from normal and malignant tissues in patients with colorectal cancer, and examined the expression of beta1 and beta2 integrins on these lymphocytes quan...

journal_title：Annals of surgical oncology

authors： Kitayama J,Tuno N,Nakayama H,Shibata Y,Muto T,Nagawa H

更新日期：1999-07-01 00:00:00

abstract：PURPOSE:To investigate the relationship between surgeon caseload and surgery type, and variation in the surgical treatment of early stage breast cancer patients in Alberta, Canada. METHODS:All women diagnosed with stage I to III breast cancer in Alberta from 2002 to 2010 were identified from the Alberta Cancer Registr...

journal_title：Annals of surgical oncology

authors： Fisher S,Yasui Y,Dabbs K,Winget M

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:We postulated that the worse prognosis of melanoma with advancing age reflected more aggressive tumor biology and that in younger patients the prognosis would be more favorable. MATERIALS AND METHODS:The expanded AJCC melanoma staging database contained 11,088 patients with complete data for analysis, inclu...

journal_title：Annals of surgical oncology

authors： Balch CM,Soong SJ,Gershenwald JE,Thompson JF,Coit DG,Atkins MB,Ding S,Cochran AJ,Eggermont AM,Flaherty KT,Gimotty PA,Johnson TM,Kirkwood JM,Leong SP,McMasters KM,Mihm MC Jr,Morton DL,Ross MI,Sondak VK

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:The aim of this retrospective study was to investigate the incidence of mesenteric lymph node (MLN) involvement, and its prognostic role in advanced ovarian cancer (OC). METHODS:OC patients undergoing rectosigmoid resection during primary debulking surgery or interval debulking surgery were recorded. Progre...

journal_title：Annals of surgical oncology

authors： Gallotta V,Fanfani F,Fagotti A,Chiantera V,Legge F,Gueli Alletti S,Nero C,Margariti AP,Papa V,Alfieri S,Ciccarone F,Scambia G,Ferrandina G

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Survival for positive sentinel lymph node (SLN) patients does not differ between completion lymph node dissection (CLND) and nodal observation (OBS). However, treating these patients with CLND and checkpoint inhibitors, such as pembrolizumab (PEM), improves outcomes. This study evaluated the cost-effectivene...

journal_title：Annals of surgical oncology

authors： Standage H,Hersh AR,Caughey A,Taylor M,Vetto J,Han D

更新日期：2020-09-19 00:00:00

abstract：BACKGROUND:Whether thyroidectomy for metastases to the thyroid is associated with a survival benefit remains debatable; in general, palliation and disease control are accepted goals in this setting. We evaluated the clinical features and overall survival of patients with thyroid metastasis treated by thyroid resection ...

journal_title：Annals of surgical oncology

authors： Romero Arenas MA,Ryu H,Lee S,Morris LF,Grubbs EG,Lee JE,Perrier ND

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Extensive lymph node dissection (LND) is beneficial in primarily resected esophageal cancer patients. Such benefit was believed to be seen in neoadjuvant chemoradiotherapy (CRT)-treated patients, but evidence was inconsistent. We hypothesized that CRT might offset the benefit of LND in certain subgroup of pa...

journal_title：Annals of surgical oncology

authors： Chao YK,Liu HP,Hsieh MJ,Wu YC,Liu YH,Yeh CH,Chang HK,Tseng CK

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Pancreatic adenocarcinoma impinging the portal and/or superior mesenteric vein (PV-SMV) is classified as borderline resectable, and preoperative chemoradiation is recommended to increase the margin-negative resection rate. There is no consensus about what degree of venous impingement constitutes borderline r...

journal_title：Annals of surgical oncology

authors： Chun YS,Milestone BN,Watson JC,Cohen SJ,Burtness B,Engstrom PF,Haluszka O,Tokar JL,Hall MJ,Denlinger CS,Astsaturov I,Hoffman JP

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:This meta-analysis aimed to investigate the value of preoperative sarcopenia in predicting complications after esophagectomy. Clinicopathologic characteristics of sarcopenia patients, which may support sarcopenia management, also were studied. METHODS:This study searched for articles describing an associati...

journal_title：Annals of surgical oncology

authors： Wang PY,Xu LD,Chen XK,Xu L,Yu YK,Zhang RX,Sun HB,Wu HL,Li Y

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) is the preferred treatment for selected patients with mucinous appendiceal adenocarcinoma. Frequently, the hemidiaphragms are infiltrated with tumor, requiring partial diaphragm resection (DR) in order to obtain complete cytoreductio...

journal_title：Annals of surgical oncology

authors： Grotz TE,Mansfield PF,Royal RE,Mann GN,Rafeeq S,Beaty KA,Overman MJ,Fournier KF

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:Recent studies indicated that the scaffolding adaptor protein GAB2 (GRB2-associated binding protein 2) plays a critical role in the proliferation and migration of various cancers. This study aimed to determine the role of aberrant GAB2 expression in human colorectal cancer (CRC). METHODS:Quantitative real-time...

journal_title：Annals of surgical oncology

authors： Matsumura T,Sugimachi K,Takahashi Y,Uchi R,Sawada G,Ueda M,Hirata H,Sakimura S,Ueo H,Takano Y,Kurashige J,Shinden Y,Eguchi H,Sudo T,Yamamoto H,Doki Y,Mori M,Mimori K

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:The sentinel lymph node (SLN) is the first lymph node in the regional nodal basin to receive metastatic cells. In-transit nodes are found between the primary melanoma site and regional nodal basins. To date, this is one of the first reports on micrometastasis to in-transit nodes. METHODS:Retrospective datab...

journal_title：Annals of surgical oncology

authors： Thelmo MC,Morita ET,Treseler PA,Nguyen LH,Allen RE Jr,Sagebiel RW,Kashani-Sabet M,Leong SP

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:Malignant ascites (MA) is a distressing problem usually managed by repeated paracenteses. Paracentesis represents a meaningful time point in identifying patients with a specific presentation. OBJECTIVE:The objective of this study is to examine symptom clustering in MA patients at paracentesis. METHODS:Pre-...

journal_title：Annals of surgical oncology

authors： Husain A,Bezjak A,Easson A

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:The prognosis of biliary tract cancer (BTC) is unfavorable due to its chemoresistance. Hypoxia triggers epithelial-to-mesenchymal transition (EMT), which is closely related to drug resistance. In this study, we focused on the functional roles of procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2), a h...

journal_title：Annals of surgical oncology

authors： Okumura Y,Noda T,Eguchi H,Sakamoto T,Iwagami Y,Yamada D,Asaoka T,Wada H,Kawamoto K,Gotoh K,Kobayashi S,Takeda Y,Tanemura M,Umeshita K,Doki Y,Mori M

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Angiotensin 2 is a key biologic peptide in the renin-angiotensin system (RAS) that regulates blood pressure and renal hemodynamics. The potential role of the RAS in the promotion of tumor growth, angiogenesis, and metastasis also has been shown in the past few decades. This study investigated the prognostic ...

journal_title：Annals of surgical oncology

authors： Miyajima A,Yazawa S,Kosaka T,Tanaka N,Shirotake S,Mizuno R,Kikuchi E,Oya M

更新日期：2015-10-01 00:00:00