What is the Cost-Effective Treatment for Melanoma Patients with a Positive Sentinel Node?

abstract：BACKGROUND:The prognosis of biliary tract cancer (BTC) is unfavorable due to its chemoresistance. Hypoxia triggers epithelial-to-mesenchymal transition (EMT), which is closely related to drug resistance. In this study, we focused on the functional roles of procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2), a h...

journal_title：Annals of surgical oncology

authors： Okumura Y,Noda T,Eguchi H,Sakamoto T,Iwagami Y,Yamada D,Asaoka T,Wada H,Kawamoto K,Gotoh K,Kobayashi S,Takeda Y,Tanemura M,Umeshita K,Doki Y,Mori M

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:The National Comprehensive Cancer Network (NCCN) recommends that at least 15 lymph nodes (LNs) be removed during radical gastrectomy. This study aims to investigate the optimal number of LNs resected for radical gastrectomy. PATIENTS AND METHODS:From September 2008 to March 2015, a total of 1990 gastric can...

journal_title：Annals of surgical oncology

authors： Zheng G,Feng F,Guo M,Xu G,Liu S,Liu Z,Sun L,Hong L,Yang J,Lian X,Fan D,Zhang H

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Gemcitabine has been shown to exhibit significant clinical activity against pancreatic cancer and has become a first-line chemotherapeutic for this disease in recent years. However, there are still many patients who do not respond to this treatment and it is expected to improve the clinical outcome if we can...

journal_title：Annals of surgical oncology

authors： Takano S,Togawa A,Yoshitomi H,Shida T,Kimura F,Shimizu H,Yoshidome H,Ohtsuka M,Kato A,Tomonaga T,Nomura F,Miyazaki M

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Among all in-breast tumor recurrences (IBTR) following breast-conserving therapy (BCT), some comprise metachronous new primaries (NPs) while others are true recurrences (TRs). Establishing this distinction remains a challenge. METHODS:We studied 3932 women who underwent BCT for stage I-III breast cancer fro...

journal_title：Annals of surgical oncology

authors： Laird J,Lok B,Siu C,Cahlon O,Khan AJ,McCormick B,Powell SN,Cody H,Wen HY,Ho A,Braunstein LZ

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Microinvasive ductal carcinoma (DCISM), defined as DCIS with a focus of invasive carcinoma ≤ 1 mm, can be managed similarly to pure DCIS; however, management of the axilla in DCISM has been a subject of debate. Reports in the literature differ on the utility and necessity of sentinel lymph node biopsy (SLNB)...

journal_title：Annals of surgical oncology

authors： Fan B,Pardo JA,Serres S,Alapati AC,Szewczyk J,Mele A,James TA

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:It is still controversial whether tumor size (Ts) should be considered an important indicator for evaluation the prognosis of gastric cancer (GC). The purpose of this study was to elucidate the prognostic prediction superiority of Ts in the large-scale cohort of GC patients. METHODS:Data from 1,521 patients...

journal_title：Annals of surgical oncology

authors： Deng J,Zhang R,Pan Y,Ding X,Cai M,Liu Y,Liu H,Bao T,Jiao X,Hao X,Liang H

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Extramammary Paget's disease (EMPD) is a rare intraepithelial malignancy with poorly described outcomes. EMPD in men is primarily found in the perianal and penoscrotal areas. We assessed incidence and time trends of EMPD in men as well as extent and predictors of survival using the Surveillance, Epidemiology...

journal_title：Annals of surgical oncology

authors： Herrel LA,Weiss AD,Goodman M,Johnson TV,Osunkoya AO,Delman KA,Master VA

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:We evaluated the use and efficacy of adjuvant chemotherapy after resection of T1-2N1M0 non-small cell lung cancer (NSCLC) in elderly patients. METHODS:Factors associated with the use of adjuvant chemotherapy in patients older than 65 years of age who underwent surgical resection of T1-2N1M0 NSCLC without in...

journal_title：Annals of surgical oncology

authors： Berry MF,Coleman BK,Curtis LH,Worni M,D'Amico TA,Akushevich I

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Health care reform places primary care (PC) physicians in an increasingly significant role for breast cancer screening and diagnosis. This study assessed the adequacy of traditional PC resident training to prepare physicians for this front-line role. METHODS:Sixty-eight primary care residents, representing ...

journal_title：Annals of surgical oncology

authors： Chalabian J,Formenti S,Russell C,Pearce J,Dunnington G

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:This study aimed to evaluate the prognostic significance of the Oncotype DX recurrence score (RS) in T1-2N1M0 estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer based on the prognostic stage in the updated American Joint Commission on Cancer, 8th edition. ...

journal_title：Annals of surgical oncology

authors： Wang M,Wu K,Zhang P,Zhang M,Ding A,Chen H

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Carefully selected patients with noncolorectal, nonneuroendocrine (NCNN) liver metastases may benefit from hepatic resection. The incidence of occult unresectable disease and the possible benefits of staging laparoscopy in these patients are not known. METHODS:From December 1997 to July 2000, staging laparo...

journal_title：Annals of surgical oncology

authors： D'Angelica M,Jarnagin W,Dematteo R,Conlon K,Blumgart LH,Fong Y

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Nipple-sparing mastectomy (NSM) for both risk reduction and cancer is increasing. In the cancer setting, most studies suggest the use of both clinical and intraoperative biopsy criteria in patient selection. This study examines the use of both biopsy and clinical criteria in women undergoing total nipple-rem...

journal_title：Annals of surgical oncology

authors： Stolier A,Stone JC,Moroz K,Hanemann CW,McNabb L,Jones SD,Lacey M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Poly(ADP-ribose) polymerase (PARP) is an important regulator of programmed cell death in response to alkylating agents such as temozolomide (TMZ). The goal of this study was to determine if a systemically administered PARP-inhibitor (INO-1001) could augment the efficacy of TMZ in a rat model of extremity mal...

journal_title：Annals of surgical oncology

authors： Toshimitsu H,Yoshimoto Y,Augustine CK,Padussis JC,Yoo JS,Angelica Selim M,Pruitt SK,Friedman HS,Ali-Osman F,Tyler DS

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:The prognosis for patients with locally advanced thoracic esophageal cancer is extremely unfavorable. We have been administering neoadjuvant chemoradiotherapy (CRT) followed by esophagectomy to these patients and studying whether REG I expression in untreated endoscopic biopsy specimens is predictive of pati...

journal_title：Annals of surgical oncology

authors： Motoyama S,Sugiyama T,Ueno Y,Okamoto H,Takasawa S,Nanjo H,Watanabe H,Maruyama K,Okuyama M,Ogawa J

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Preoperative injection of radiocolloid before a sentinel lymph node (SLN) biopsy is painful for patients with breast cancer. Injection after anesthesia eliminates this discomfort but allows less time for radiocolloid migration. Our goal was to validate the efficacy of intraoperative injection. METHODS:In th...

journal_title：Annals of surgical oncology

authors： Stell VH,Flippo-Morton TS,Norton HJ,White RL Jr

更新日期：2009-08-01 00:00:00

abstract：INTRODUCTION:To identify melanoma patients at sufficiently low risk of nodal metastases who could avoid sentinel lymph node biopsy (SLNB), several statistical models have been proposed based upon patient/tumor characteristics, including logistic regression, classification trees, random forests, and support vector machi...

journal_title：Annals of surgical oncology

authors： Sabel MS,Rice JD,Griffith KA,Lowe L,Wong SL,Chang AE,Johnson TM,Taylor JM

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the usefulness of shear wave elastography (SWE) for predicting cervical lymph node (LN) metastasis and the prognostic implication of SWE as histopathologic factors of papillary thyroid carcinoma (PTC). METHODS:Eighty-four LNs of 66 patients with PTC underwent B-mode ultras...

journal_title：Annals of surgical oncology

authors： Jung WS,Kim JA,Son EJ,Youk JH,Park CS

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Postoperative recurrence of hepatocellular carcinoma (HCC) is a major problem after surgical resection. To date, adjuvant chemotherapy or other adjuvant modalities have not been proven effective in preventing or delaying recurrence. The aim of this prospective randomized study was to evaluate the effectivene...

journal_title：Annals of surgical oncology

authors： Xia Y,Qiu Y,Li J,Shi L,Wang K,Xi T,Shen F,Yan Z,Wu M

更新日期：2010-12-01 00:00:00

abstract：:The number of early gastric cancer (EGC) cases has been increasing because of improved diagnostic procedures. Applications of function-preserving gastric cancer surgery may therefore also be increasing because of its low incidence of lymph node metastasis, excellent survival rates, and the possibility of less-invasive...

journal_title：Annals of surgical oncology

authors： Hiki N,Nunobe S,Kubota T,Jiang X

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:This work is aimed at comparing mucinous colorectal adenocarcinomas (MUC) and non-mucinous colorectal adenocarcinomas (non-MUC), and at verifying the existence of two different subgroups of MUC, in terms of clinicopathological features, chromosomal alterations, and outcome, in a geographical area where mucin...

journal_title：Annals of surgical oncology

authors： Leopoldo S,Lorena B,Cinzia A,Gabriella DC,Angela Luciana B,Renato C,Antonio M,Carlo S,Cristina P,Stefano C,Maurizio T,Luigi R,Cesare B

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:The clinical impact of sentinel lymph node biopsy (SLNB) in gastric cancer is controversial. We performed a prospective trial to compare different methods: radiocolloid method (RM), dye method (DM), and both methods simultaneously (dual method, or DUM) for reliability and therapeutic consequences. METHODS:R...

journal_title：Annals of surgical oncology

authors： Gretschel S,Bembenek A,Hünerbein M,Dresel S,Schneider W,Schlag PM

更新日期：2007-07-01 00:00:00

abstract：PURPOSE:To prospectively determine the rate of malignancy after surgery in papillary lesions initially diagnosed at ultrasound (US)-guided 11-gauge vacuum-assisted breast biopsies. METHODS:Between May 2007 and December 2009, a total of 85 papillary lesions, including 73 benign papillomas and 12 atypical papillomas wer...

journal_title：Annals of surgical oncology

authors： Chang JM,Han W,Moon WK,Cho N,Noh DY,Park IA,Jung EJ

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Gastrointestinal leak (GIL) after cytoreductive surgery with heated intraperitoneal chemotherapy (CRS/HIPEC) is associated with significant morbidity and mortality. This study aimed to identify GIL prognostic factors and its impact on overall survival. METHODS:A retrospective analysis of a prospectively mai...

journal_title：Annals of surgical oncology

authors： Chouliaras K,Levine EA,Fino N,Shen P,Votanopoulos KI

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Follow-up practices after diagnosis and treatment of primary cutaneous melanoma vary considerably. We aimed to determine factors associated with recommendations for follow-up setting, frequency, skin surveillance, and concordance with clinical guidelines. METHODS:The population-based Melanoma Patterns of Ca...

journal_title：Annals of surgical oncology

authors： Read RL,Madronio CM,Cust AE,Goumas C,Watts CG,Menzies S,Curtin AM,Mann G,Thompson JF,Morton RL

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:Preoperative and postoperative RT for the treatment of high-grade soft-tissue sarcoma result in similar local control and overall survival rates, but morbidities differ. Postoperative RT is associated with a higher rate of long-term fibrosis, edema, and joint stiffness. Preoperative RT is associated with higher...

journal_title：Annals of surgical oncology

authors： Baldini EH,Lapidus MR,Wang Q,Manola J,Orgill DP,Pomahac B,Marcus KJ,Bertagnolli MM,Devlin PM,George S,Abraham J,Ferrone ML,Ready JE,Raut CP

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:To investigate the prognostic value of positive-to-negative changes in hormone receptor (HR) status after neoadjuvant chemotherapy (NCT) in patients with HR-positive breast cancer. METHODS:Data from 224 stage II-III breast cancer patients with positive HR status before NCT who had residual disease in the br...

journal_title：Annals of surgical oncology

authors： Chen S,Chen CM,Yu KD,Zhou RJ,Shao ZM

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Accumulated evidence indicates that the incidence of early-onset breast cancer has rapidly increased in Taiwan and other Asian compared to Western countries. The mismatch repair (MMR) pathway might be one of the crucial mechanisms of predisposition to early breast cancer. In this study, we explored whether M...

journal_title：Annals of surgical oncology

authors： Hsieh YC,Cho EC,Tu SH,Wu CH,Hung CS,Hsieh MC,Su CT,Liu YR,Lee CH,Ho YS,Chiou HY

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Newer multigene molecular profiling assays for breast carcinoma rely heavily on the quantification of genes of proliferation, whereas traditional histological grading reports the mitotic count. The mitotic activity of invasive breast carcinomas may be undervalued; therefore, an evaluation of the prognostic s...

journal_title：Annals of surgical oncology

authors： Chang JM,McCullough AE,Dueck AC,Kosiorek HE,Ocal IT,Lidner TK,Gray RJ,Wasif N,Northfelt DW,Anderson KS,Pockaj BA

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Cytoreductive therapy for metastatic carcinoid provides symptomatic relief and improvement in overall survival. We evaluated whether CgA and 5HIAA could predict symptomatic relief and control of disease progression after cytoreductive surgery. METHODS:We retrospectively reviewed 70 patients who underwent cy...

journal_title：Annals of surgical oncology

authors： Jensen EH,Kvols L,McLoughlin JM,Lewis JM,Alvarado MD,Yeatman T,Malafa M,Shibata D

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Despite decreasing rates of subsequent contralateral breast cancer after diagnosis of unilateral primary breast cancer, the proportion of patients electing contralateral prophylactic mastectomy (CPM) is increasing. Our aim was to identify risk factors associated with the identification of occult malignancy (...

journal_title：Annals of surgical oncology

authors： Erdahl LM,Boughey JC,Hoskin TL,Degnim AC,Hieken TJ

更新日期：2016-01-01 00:00:00