Sarcopenia and Short-Term Outcomes After Esophagectomy: A Meta-analysis.


BACKGROUND:This meta-analysis aimed to investigate the value of preoperative sarcopenia in predicting complications after esophagectomy. Clinicopathologic characteristics of sarcopenia patients, which may support sarcopenia management, also were studied. METHODS:This study searched for articles describing an association between sarcopenia and short-term outcomes after esophagectomy using PubMed, EMBASE, and the Cochrane Library. Mantel-Haenszel and inverse variance models were used for the meta-analyses of end points. RESULTS:The meta-analysis included 14 studies comprising a total of 2387 patients. Sarcopenia was significantly associated with advanced age (weighted mean difference [WMD], 3.48; 95% confidence interval [CI], 2.22-4.74), lower body mass index (WMD - 2.22; 95% CI - 2.65 to - 1.79), squamous cell carcinoma (odds ratio [OR], 2.78; 95% CI 1.72-4.47), advanced clinical tumor stage (OR 1.65; 95% CI 1.28-2.15), and neoadjuvant therapy (OR 1.87; 95% CI 1.38-2.53). The sarcopenia patients showed lower preoperative albumin levels (WMD - 0.11; 95% CI - 0.19 to - 0.04) than the nonsarcopenia patients. Sarcopenia was significantly predictive of pneumonia (OR 2.58; 95% CI 1.75-3.81) and overall complications (OR 1.52; 95% CI 1.07-2.15) after esophagectomy. The sarcopenia patients also showed nonsignificant increases in the risks of anastomotic leakage (OR 1.29; 95% CI 0.99-1.67), vocal cord palsy (OR 2.03; 95% CI 0.89-4.64), and major complications (≥ Clavien-Dindo grade III; OR 1.30; 95% CI 0.95-1.79) but not increased operation time, blood loss, or mortality. CONCLUSIONS:Preoperative sarcopenia assessment showed considerable potential for predicting postoperative complications for esophageal cancer patients. To realize this potential, more effective diagnostic criteria and severity classifications for sarcopenia are warranted.


Ann Surg Oncol


Wang PY,Xu LD,Chen XK,Xu L,Yu YK,Zhang RX,Sun HB,Wu HL,Li Y




Has Abstract


2020-08-01 00:00:00














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    abstract:PURPOSE:Our aim was to investigate the detrusor muscle sampling rate after monopolar versus bipolar transurethral resection of bladder tumor (TURBT). METHODS:This was a single-center, prospective, randomized, phase III trial on monopolar versus bipolar TURBT. Baseline patient characteristics, disease characteristics a...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,随机对照试验


    authors: Teoh JY,Chan ES,Yip SY,Tam HM,Chiu PK,Yee CH,Wong HM,Chan CK,Hou SS,Ng CF

    更新日期:2017-05-01 00:00:00

  • A comparison of clinical and pathologic assessments for the prediction of occult nipple involvement in nipple-sparing mastectomies.

    abstract:BACKGROUND:Nipple-sparing mastectomy (NSM) for both risk reduction and cancer is increasing. In the cancer setting, most studies suggest the use of both clinical and intraoperative biopsy criteria in patient selection. This study examines the use of both biopsy and clinical criteria in women undergoing total nipple-rem...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章


    authors: Stolier A,Stone JC,Moroz K,Hanemann CW,McNabb L,Jones SD,Lacey M

    更新日期:2013-01-01 00:00:00

  • Modified Appleby Procedure, Distal Splenopancreatectomy with Celiac Axis Resection.

    abstract:BACKGROUND:Modified Appleby procedure could be indicated in stage III locally advanced body pancreatic ductal adenocarcinoma (PDAC) involving the celiac axis after neoadjuvant treatment. PATIENTS AND METHODS:We report the case of a 38-year-old woman presenting a tumor arising from the body of the pancreas, involving t...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章


    authors: Triki H,Bergeat D,Bougard M,Robin F,Sulpice L

    更新日期:2020-10-21 00:00:00

  • Morbidity associated with colostomy reversal after cytoreductive surgery and HIPEC.

    abstract:BACKGROUND:Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has improved the survival in selected colorectal cancer patients with peritoneal metastases. In these patients, the risk of a low anastomosis is sometimes diminished through the creation of a colostomy. Currently, the morbidity...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章


    authors: de Cuba EM,Verwaal VJ,de Hingh IH,van Mens LJ,Nienhuijs SW,Aalbers AG,Bonjer HJ,te Velde EA

    更新日期:2014-03-01 00:00:00

  • Size of Sentinel Node Metastasis Predicts Non-sentinel Node Involvement in Endometrial Cancer.

    abstract:PURPOSE:To analyze the relationship between the size of metastatic sentinel lymph nodes (SLNs) and the risk of non-sentinel lymph node (non-SLN) metastasis in endometrial cancer. PATIENTS AND METHODS:From a total of 328 patients with endometrial cancer who underwent SLN mapping from January 2013 to April 2019, 142 pat...

    journal_title:Annals of surgical oncology

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    更新日期:2020-05-01 00:00:00

  • Laparoscopic detection of sentinel lymph nodes in gastrointestinal cancer: a novel and minimally invasive approach.

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    journal_title:Annals of surgical oncology

    pub_type: 杂志文章


    authors: Kitagawa Y,Ohgami M,Fujii H,Mukai M,Kubota T,Ando N,Watanabe M,Otani Y,Ozawa S,Hasegawa H,Furukawa T,Matsuda J,Kumai K,Ikeda T,Kubo A,Kitajima M

    更新日期:2001-10-01 00:00:00

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    abstract:BACKGROUND:Laparoscopy-assisted distal gastrectomy (LADG) for gastric cancer may prevent the development of an impaired nutritional status due to reduced surgical stress compared with open distal gastrectomy (ODG). METHODS:This study was performed as an exploratory analysis of a phase III trial comparing LADG and ODG ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,随机对照试验


    authors: Aoyama T,Yoshikawa T,Hayashi T,Hasegawa S,Tsuchida K,Yamada T,Cho H,Ogata T,Fujikawa H,Yukawa N,Oshima T,Rino Y,Masuda M

    更新日期:2014-06-01 00:00:00

  • Strategies to Increase the Resectability of Patients with Colorectal Liver Metastases: A Multi-center Case-Match Analysis of ALPPS and Conventional Two-Stage Hepatectomy.

    abstract:BACKGROUND:Two-stage hepatectomy (TSH) is well established for the treatment of patients who have colorectal cancer liver metastases (CRLM) with a small liver remnant. The technique of associating liver partitioning and portal vein occlusion for staged hepatectomy (ALPPS) has been advocated as a novel tool to increase ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,多中心研究


    authors: Ratti F,Schadde E,Masetti M,Massani M,Zanello M,Serenari M,Cipriani F,Bonariol L,Bassi N,Aldrighetti L,Jovine E

    更新日期:2015-01-01 00:00:00

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    abstract:: ...

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    pub_type: 社论


    authors: Yasui W

    更新日期:2019-04-01 00:00:00

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    更新日期:2016-09-01 00:00:00

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    authors: Patterson SG,Teller P,Iyengar R,Carlson GW,Gabram-Mendola SG,Losken A,Styblo T,Torres M,Wood WC,Perez SD,Mosunjac M,Rizzo M

    更新日期:2012-08-01 00:00:00

  • Surgical resection of primary tumors in patients who present with stage IV colorectal cancer: an analysis of surveillance, epidemiology, and end results data, 1988 to 2000.

    abstract:BACKGROUND:Surgical resection of the primary tumor for patients who present with incurable stage IV colorectal cancer is controversial. National practice patterns have not been described. We evaluated the use of primary tumor resection in patients presenting with stage IV colorectal cancer. METHODS:Patients with stage...

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    pub_type: 杂志文章


    authors: Cook AD,Single R,McCahill LE

    更新日期:2005-08-01 00:00:00

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    authors: Ceelen WP,Van Nieuwenhove Y,Van Belle S,Denys H,Pattyn P

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    authors: Weber RS,Jabbour N,Martin RC 2nd

    更新日期:2008-01-01 00:00:00

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    authors: Akamine T,Tagawa T,Ijichi K,Toyokawa G,Takamori S,Hirai F,Okamoto T,Oda Y,Maehara Y

    更新日期:2019-05-01 00:00:00

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    authors: Medina-Franco H,Heslin MJ,Cortes-Gonzalez R

    更新日期:2000-08-01 00:00:00

  • Identification of Patients for Adjuvant Therapy After Resection of Carcinoma of the Extrahepatic Bile Ducts: A Propensity Score-Matched Analysis.

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    authors: Ecker BL,Vining CC,Roses RE,Maggino L,Lee MK,Drebin JA,Fraker DL,Vollmer CM Jr,Datta J

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  • Aesthetics in breast conserving therapy: do objectively measured results match patients' evaluations?

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    authors: Heil J,Dahlkamp J,Golatta M,Rom J,Domschke C,Rauch G,Cardoso MJ,Sohn C

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  • Adjuvant brachytherapy for primary high-grade soft tissue sarcoma of the extremity.

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    journal_title:Annals of surgical oncology

    pub_type: 杂志文章


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  • Patterns of Local Recurrence and Oncologic Outcomes in T3 Low Rectal Cancer (≤5 cm from the Anal Verge) Treated With Short-Course Radiotherapy With Delayed Surgery : Outcomes in T3 Low Rectal Cancer Treated With Short-Course Radiotherapy With Delayed Surg

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    journal_title:Annals of surgical oncology

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    authors: Beppu N,Kimura F,Aihara T,Doi H,Tomita N,Yanagi H,Yamanaka N

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  • Using Multilevel Models to Explain Variation in Clinical Practice: Surgeon Volume and the Surgical Treatment of Breast Cancer.

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    pub_type: 杂志文章


    authors: Fisher S,Yasui Y,Dabbs K,Winget M

    更新日期:2016-06-01 00:00:00

  • The Chicago Consensus on Peritoneal Surface Malignancies: Management of Colorectal Metastases.

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    journal_title:Annals of surgical oncology

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    authors: Chicago Consensus Working Group.

    更新日期:2020-06-01 00:00:00

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    pub_type: 杂志文章


    authors: Kobayashi H,Kikuchi A,Okazaki S,Ishiguro M,Ishikawa T,Iida S,Uetake H,Sugihara K

    更新日期:2015-01-01 00:00:00

  • Changing the Default: A Prospective Study of Reducing Discharge Opioid Prescription after Lumpectomy and Sentinel Node Biopsy.

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    pub_type: 杂志文章


    authors: Moo TA,Pawloski KR,Sevilimedu V,Charyn J,Simon BA,Sclafani LM,Plitas G,Barrio AV,Kirstein LJ,Van Zee KJ,Morrow M

    更新日期:2020-11-01 00:00:00

  • Predictors for locoregional recurrence for clinical stage III-N2 non-small cell lung cancer with nodal downstaging after induction chemotherapy and surgery.

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    journal_title:Annals of surgical oncology

    pub_type: 杂志文章


    authors: Amini A,Lou F,Correa AM,Baldassarre R,Rimner A,Huang J,Roth JA,Swisher SG,Vaporciyan AA,Lin SH

    更新日期:2013-06-01 00:00:00

  • Liver resection for colorectal metastases in presence of extrahepatic disease: results from an international multi-institutional analysis.

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    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,多中心研究


    authors: Pulitanò C,Bodingbauer M,Aldrighetti L,de Jong MC,Castillo F,Schulick RD,Parks RW,Choti MA,Wigmore SJ,Gruenberger T,Pawlik TM

    更新日期:2011-05-01 00:00:00

  • Verification of musculoskeletal FDG-PET-CT findings performed for melanoma staging.

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    journal_title:Annals of surgical oncology

    pub_type: 临床试验,杂志文章


    authors: Mansour AA 3rd,Kelley MC,Hatmaker AR,Holt GE,Schwartz HS

    更新日期:2010-04-01 00:00:00

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    journal_title:Annals of surgical oncology

    pub_type: 杂志文章


    authors: Wasif N,Ko CY,Farrell J,Wainberg Z,Hines OJ,Reber H,Tomlinson JS

    更新日期:2010-09-01 00:00:00

  • Impact of the Interval Between Neoadjuvant Chemotherapy and Gastrectomy on Short- and Long-Term Outcomes for Patients with Advanced Gastric Cancer.

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    journal_title:Annals of surgical oncology

    pub_type: 杂志文章


    authors: Bausys A,Ümarik T,Luksta M,Reinsoo A,Rackauskas R,Anglickiene G,Kryzauskas M,Tõnismäe K,Senina V,Seinin D,Bausys R,Strupas K

    更新日期:2021-01-08 00:00:00

  • Basal subtype, as approximated by triple-negative phenotype, is associated with locoregional recurrence in a case-control study of women with 0-3 positive lymph nodes after mastectomy.

    abstract:PURPOSE:Basal subtype, as approximated by the triple-negative phenotype (ER-PR-Her2-), has correlated with higher LRR in recent studies. Indications for postmastectomy RT (PMRT) in women with 0-3 positive lymph nodes remain unclear. We evaluated the importance of biologic subtype in a cohort of women with LRR after mas...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章


    authors: Khan AJ,Milgrom SA,Barnard N,Higgins SA,Moran M,Shahzad H,Kim S,Goyal S,Al-Faraj F,Kirstein L,Kearney T,Haffty BG

    更新日期:2014-06-01 00:00:00